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The OpenOx Collaborative Community

June 4, 2024

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Fiffi Negussie, MPH

Program Manager

Center for Health Equity in Surgery and Anesthesia

University of California San Francisco

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HYPOXIA LAB

hypoxialab.org

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CHESA

HYPOXIA LAB

hypoxialab.org

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Collaborative Community Overview

  • Convene 220 diverse, global experts and stakeholders from over 18 countries
    • Identify challenges through clinical and laboratory research
    • Facilitate data sharing
    • Advocate to improve best practices and standards
    • Advance innovation, safety, and equity

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openoximetry.org/community

CHESA

HYPOXIA LAB

hypoxialab.org

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Collaborative Community Overview

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openoximetry.org/community

CHESA

HYPOXIA LAB

hypoxialab.org

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Collaborative Community Subgroups

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openoximetry.org/community

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Clinical Trials

Harmonizing & expanding data collection protocols

Skin Color Diversity

Developing best practices for diversity in oximeter studies

Education & Comms

Communicating best practices for safe oximeter use

Data Sharing

Scaling and harmonizing available oximeter data for R&D

CHESA

HYPOXIA LAB

hypoxialab.org

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Clinical Trials Subgroup

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openoximetry.org/community

  • Objectives
    • Harmonize and expanding data collection protocols
    • Collaborate with studies across 8 sites
    • 6 study protocols developed and shared publicly

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CHESA

HYPOXIA LAB

hypoxialab.org

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Clinical Trials Subgroup

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openoximetry.org/community

  • Next steps
    • Awaiting trials to be completed
    • Analyses and raw data to be shared subsequently

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CHESA

HYPOXIA LAB

hypoxialab.org

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Education & Comms Subgroup

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openoximetry.org/community

  • Objectives
    • Communicate best practices for safe oximeter use through locally-relevant materials that are easy to understand

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CHESA

HYPOXIA LAB

hypoxialab.org

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Education & Comms Subgroup

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openoximetry.org/community

  • Next steps
    • Develop and disseminate a living infographic focusing on optimal use of pulse oximeters
    • Publish v1 in June

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CHESA

HYPOXIA LAB

hypoxialab.org

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Build your own infographic

Homecare

Neonates

Inpatient

General Overview

CHESA

HYPOXIA LAB

hypoxialab.org

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Skin Color Diversity Subgroup

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openoximetry.org/community

  • Objectives
    • Develop best practices for skin color diversity and measurement
    • Harmonize relationship between subjective and objective measures to inform standards

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CHESA

HYPOXIA LAB

hypoxialab.org

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Skin Color Diversity Subgroup

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openoximetry.org/community

  • Next steps
    • Develop Diversity Toolkit for medical device researchers on appropriate use use of race, ethnicity and skin color and conducting equitable research
    • Publish v1 by July

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CHESA

HYPOXIA LAB

hypoxialab.org

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Diversity Toolkit

CHESA

HYPOXIA LAB

hypoxialab.org

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Diversity Toolkit

CHESA

HYPOXIA LAB

hypoxialab.org

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Skin Color Diversity Subgroup

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openoximetry.org/community

  • Next steps
    • Conduct study to characterize range of skin color across Africa
      • using subjective and objective measures of skin color
      • high cost and low cost devices for comparison

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CHESA

HYPOXIA LAB

hypoxialab.org

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Data Sharing Objectives

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openoximetry.org/community

  • Objectives
    • Accelerate progress by creating large datasets to answer complex questions
    • Publicly available raw oximeter data
      • With standardize definitions and data structures
      • Leveraging standardized study protocols

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CHESA

HYPOXIA LAB

hypoxialab.org

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Open Ox Data Repository

openoximetry.org/data-repository

CHESA

HYPOXIA LAB

hypoxialab.org

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Data Sharing Objectives

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openoximetry.org/community

  • Next steps
    • Collaborate with study teams to gather and publish more raw data
    • Share manuscript on methodology

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CHESA

HYPOXIA LAB

hypoxialab.org

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Next Steps for Collaborative Community

  • Build medical device testing capacity in Uganda for more diverse data collection and equity in device manufacturing
  • OpenOx CC meeting August 2024
  • Subgroups will continue to convene on a quarterly basis

CHESA

HYPOXIA LAB

hypoxialab.org

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Getting involved

Join the OpenOx CC

CHESA

HYPOXIA LAB

hypoxialab.org

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Thank you

CHESA

HYPOXIA LAB

hypoxialab.org