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IMAG/MSM Working Group on Multiscale Modeling and Viral Pandemics Mini Seminars

Jan 27, 2022

Welcome - The meeting will start at 3PM ET

 

NOTE: THE MEETING WILL BE RECORDED, STREAMED AND PUBLICLY AVAILABLE�FOR THOSE MEMBERS UNABLE TO ATTEND

Agenda

  1. Welcome
  2. Links, people, other info
  3. Social media links
  4. Quick Announcements
  5. Upcoming Mini-Seminars and Request for Future Speakers
  6. Stacey Smith?, University of Ottawa. Title: Is a COVID-19 Vaccine Likely to Make Things Worse?
  7. Vivek Kapur, Pennsylvania State University.
  8. Request for Further Business

 

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People

Co-Lead: Reinhard Laubenbacher, PhD

Department of Medicine

Laboratory for Systems Medicine

University of Florida

reinhard.laubenbacher@medicine.ufl.edu

Co-Lead: James A. Glazier, PhD

Dept. of Intelligent Systems Engineering and Biocomplexity Institute

Indiana University, Bloomington

jaglazier@gmail.com

Web Administration, Slack: James P. Sluka, PhD

Dept. of Intelligent Systems Engineering and Biocomplexity Institute

Indiana University, Bloomington

jsluka@indiana.edu

Activities Coordination: Lorenzo Veschini, PhD

King’s College London

lorenzo.veschini@gmail.com

 

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Please follow the�group on Twitter!

https://twitter.com/MsmViral

If you could re-tweet the weekly announcements �(there are usually two, one for each speaker) �that would help boost attendance and community awareness.

 

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Announcements

Any short (~1 minute) items such as;

  • announcements
  • meetings
  • funding
  • publications
  • requests for help
  • ???

 

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Schedule for Upcoming Meetings and mini-Seminars

Feb 3:

  1. Hana Dubrovolny, Texas Christian University. Title: Modeling viral coinfections of the respiratory tract.
  2. TBD

Feb 10:

  1. Kevin Janes, University of Virginia. TItle: Stress testing complete kinetic models of individualized enteroviral infection
  2. William Waites, University of Edinburgh, U.K. (tentative)

Feb 17:

  1. Juliano Gianlupi, Indiana University, Title: Coupled PK model of an antiviral and agent-based model reveal the importance of inter-cellular metabolism heterogeneity on treatment outcomes
  2. TBD

Feb 24:

  1. Hayriye Gulbudak, University of Louisiana at Lafayette. Title: Coupled systems that have in-host and between-host components for various infectious diseases.

Request for future speakers (Feb 3, …)

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Rules of the Meeting

Please mute your microphone and hold questions until after the presentations

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Mini-SeminarIs a COVID-19 Vaccine Likely to Make Things Worse?

Stacey Smith?University of Ottawa

In order to limit the disease burden and economic costs associated with the COVID-19 pandemic, it is important to understand how effective and widely distributed a vaccine must be in order to have a beneficial impact on public health. To evaluate the potential effect of a vaccine, we developed risk equations for the daily risk of COVID-19 infection both currently and after a vaccine becomes available. Our risk equations account for the basic transmission probability of COVID-19 (β) and the lowered risk due to various protection options: physical distancing; face coverings such as masks, goggles, face shields or other medical equipment; handwashing; and vaccination. We found that the outcome depends significantly on the degree of vaccine uptake: if uptake is higher than 80%, then the daily risk can be cut by 50% or more. However, if less than 40% of people get vaccinated and other protection options are abandoned—as may well happen in the wake of a COVID-19 vaccine—then introducing even an excellent vaccine will produce a worse outcome than our current situation. It is thus critical that effective education strategies are employed in tandem with vaccine rollout.

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Mini-Seminar

Vivek Kapur,Pennsylvania State University

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Requests for Input/Suggestions

  

 

We would like the subgroup leads to prepare brief presentations for the Thursday meetings, please let us know when you would like to present

Ideas/help for publicising our Thursday mini-seminars more effectively and for speakers to invite

Suggestions for agenda items and approaches to organizing the Steering Committee Meetings more effectively

There have also been a number of requests for more explicit statements of goals and tasks from the WG leadership, we would appreciate your suggestions

Please contact Reinhard Laubenbacher, James Glazier, James Sluka or Bruce Shapiro with your ideas on all of these issues

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