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Lê Vĩnh Nghi, MD

Internal Medicine Resident

VinUniversity GME Program

Update on acute headache diagnosis in Emergency Department

The 24th National Scientific Congress of Vietnam Association of Critical Care Medicine, Emergency and Clinical Toxicology

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Background

  • 96%: Experience any type headache in lifetime

  • 3 – 4%: ED chief complaints
  • 96%: benign
  • Less common: Emergencies

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04/04/2024

Burch R. The Prevalence and Impact of Migraine and Severe Headache in the United States. Headache. 2018

Tabatabai RR. Headache in the Emergency Department: Avoiding Misdiagnosis of Dangerous Secondary Causes. 2016

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Pathophysiology

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Osmosis: Headaches: Pathology review: Video & Anatomy

Gaul C. Pathophysiology of Headaches. Dtsch Med Wochenschr. 2017

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The problem

ED doctors triage

  • History and physical examination: most important
  • Immediate further testing (2nd headaches)
  • Treating common primary headaches

Early assessing danger signs: important to prevent consequence

Response to analgesics: not reliable in DDx and exclusion

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International Classification of Headache Disorders (ICHD-3)

Tabatabai RR. Headache in the Emergency Department: Avoiding Misdiagnosis of Dangerous Secondary Causes. 2016

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History taking & Physical examination

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Uptodate: Evaluation of the adult with nontraumatic headache in the emergency department

History taking

First time / Sudden onset

Worst headache

No similar headache

Change in pattern

SOCRATES

Past history

Medications, toxin�Social history

Family history

Physical examination

Level of consciousness

Vital signs

Neurologic abnormalities

Meningismus

Toxic appearance ?

Vascular: Carotid bruit

Eye: Vision, redness, pupil

Sinus: Tenderness

Dental: Infection

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The headache approach pathway

From Secondary causes to Primary causes

Tension-type

Migraine

Trigeminal autonomic

Other primary headache

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International Classification of Headache Disorders (ICHD-3)

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Important cannot-miss secondary causes

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Chinthapalli K et al. Assessment of acute headache in adults - what the general physician needs to know. Clin Med (Lond). 2018

Tabatabai RR. Headache in the Emergency Department: Avoiding Misdiagnosis of Dangerous Secondary Causes. 2016

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RED FLAGS – SNNOOP10

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Do TP et al. Red and orange flags for secondary headaches in clinical practice: SNNOOP10 list. Neurology. 2019

M S, Lamont AC. Red flags in patients presenting with headache: clinical indications for neuroimaging. Br J Radiol. 2003

or > 50 years old

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First disclaimer: Secondary headache

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New; Sudden; Progressive; Infection; ≥ 50 y.o

Neurologic sign; Cancer; Immunosuppression

→ Look for secondary headache

You are not wasting the money

Tabatabai RR. Headache in the Emergency Department: Avoiding Misdiagnosis of Dangerous Secondary Causes. 2016

Consider emergent neuroimaging

Other lab tests: CBC, CRP, LP

Check other organs too!

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Second disclaimer: Primary headache

After excluding life-threatening 2nd causes

Consult; Treat primary headache; Discharge

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Tabatabai RR. Headache in the Emergency Department: Avoiding Misdiagnosis of Dangerous Secondary Causes. 2016

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ACEP 2019 Headache Guideline

Risk-stratification strategies: Ottawa SAH Rule (B)

SAH Imaging:

Normal noncontrast head CT + normal neurologic exam w/n 6 hrs can be used to rule out SAH (B)

If still at risk for SAH and normal CT, then LP or CTA (C)

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ACEP 2019: Critical Issues in the Evaluation and Management of Adult Patients

Presenting to the Emergency Department With Acute Headache

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Case scenarios

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Case scenario

CC: 51 y.o female, no PMH, presents to ED with acute headache

HPI: Started at 5 a.m. maximal after 30 minutes, occipital area, constant, VAS 10/10, associated with nausea

  • No (fever, weakness, blurred vision, chest pain, SOB, abd pain)
  • No history of prolonged headache before, no trauma

PE: A&O x 4, HR 80, BP 140/90, T 37, SpO2 96, distress because of headache, neck stiffness (+), no weakness or sensory deficits or other abnormalities

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Lê Vĩnh Nghi – 108 Military Central Hospital

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Case scenario

  • Labs: Normal CBC, CMP, coagulation

  • Imaging: Brain CT

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Lê Vĩnh Nghi – 108 Military Central Hospital

Subarachnoid hemorrhage

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Take home messages

  • Headache in ED is a challenge
  • History of Present Illness + Past Medical History: important
  • PE: mental status, cranial nerve, motor, coordination, sensory

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Emergent imaging, lab tests for secondary causes

Maximize recognition – Minimize dangerous exclusion

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