Discovered at Western General Hospital of Edinburgh, Scotland by Dr. Patricia A. Jacobs
Found in an abnormally tall woman (5 feet 9 inches) at the age of 35. She had lost use of her ovaries before she turned 40(premature ovarian failure)
The parents of the woman were 40 and 41 when she was conceived.
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Cause
Disorder is not inherited and happens during reproduction of female reproductive cells.
An error known as nondisjunction results in an extra X chromosome.
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Chromosome Issue
A normal person has 46 chromosomes. Two of the 46 chromosomes are sex chromosomes (X and Y).
A female usually has two X chromosomes but a female with Triple X Syndrome has an extra X (3 X’s) causing 47 total chromosomes.
Sometimes women have three X chromosomes in some cells, this is known as a mosaic.
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Symptoms
Usually causes no strange physical or mental problems. Varies by patient.
Have an increased chance of learning disabilities and delayed speech.
Some patients experience an early onset of menstruation but for the most part are still fertile.
Females with Triple X are known to be abnormally tall.
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Variation in People
It has been shown that the syndrome varies greatly from person to person.
Most commonly, Triple X patients are abnormally tall.
Although these symptoms are not as common, women with Triple X syndrome can have wide set eyes, infertility, small hands, small head, lower IQ, and many more.
Randomness of symptoms is one things scientists are working to figure out.
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Triple X Syndrome in Pictures
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Diagnosis
Most common form is blood testing after birth.
Disorder is most common when the parents of the baby are of older age (usually over 40).
Can be detected during pregnancy
Use of prenatal testing can detect disorder before birth.
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Treatment
There is no single treatment
Little is known about the disorder so it is very difficult to treat.
Certain symptoms can have a cure or can be treated
For example: A girl that has developed late motor skills can work with speech therapists.
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Commonality
It is believed that Triple X Syndrome occurs in 1 out of 1,000 newborn girls
Between 5-10 babies are born with the disorder each day in the United States
Very common disorder but it is not noticeable to the average person.
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Bibliography
"Chromosomal Abnormalities | Baby | March of Dimes." Pregnancy, Baby, Prematurity, Birth Defects | March of Dimes. Dec. 2009. Web. 20 Nov. 2011. <http://www.marchofdimes.com/baby/birthdefects_chromosomal.html>.
"Triple X Syndrome - Genetics Home Reference." Genetics Home Reference - Your Guide to Understanding Genetic Conditions. Jan. 2009. Web. 20 Nov. 2011. <http://ghr.nlm.nih.gov/condition/triple-x-syndrome>.
"Triple X (XXX) Syndrome: Your Child." University of Michigan Health System. July 2010. Web. 20 Nov. 2011. <http://www.med.umich.edu/yourchild/topics/xxxsyn.htm>