Quiz: Life Sciences CSIR NET:J-16

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These are the questions from the recently conducted CSIR NET Exam in June 2016.

Name *

Questions from Life Sciences, Part 'B'

Q3. Which of the following is NOT true for cholesterol mechanism? *

1 point

HMG-CoA reductase is the key regulator of cholesterol biosynthesis

Biosynthesis takes place in cytoplasms

Reduction reactions use NADH as cofactor

Cholesterol is transported by LDL in plasma

Q1. The solubility of gases in water depends on their interaction with water molecules. Four gases, i.e. carbon dioxide, oxygen, sulphur dioxide and ammonia are dissolved in water. In terms of their solubility which of the following statements is correct? *

1 point

Ammonia > Sulphur dioxide > Carbon dioxide > Oxygen

Sulphur dioxide > Oxygeh > Ammonia > Carbon dioxide

Ammonia > Oxygen > Sulphur dioxide > Carbon dioxide

Oxygen > Carbon dioxide > Sulphur dioxide > Ammonia

Q13. Following are some of the characteristics of MHC class I and Class II molecules except one which is applicable only for MHC class I. Identify the appropriate statement *

1 point

They are expressed constitutively an all nucleated cells.

They are glycosylated polypeptides with domain structure.

They are involved in presentation of antigen fragments to cells.

They are expressed on surface membrane of B cells.

Q15. Which one of the following best defines an oncogene? *

1 point

An oncogene never codes for a cell cycle protein, which promotes cell proliferation.

Oncogenes are always involved in inherited forms of cancer.

An oncogene codes for a protein that prevents a cell from undergoing apoptosis.

An oncogene is a dominantly expressed mutated gene that renders a cell advantageous towards survival.

Q10. Error-free repair of double strand breaks in DNA is accomplished by *

1 point

non-homologous end- joining

base excision repair

homologous recombination

mismatch repair

Q5. Entry of enveloped viruses into its host cells is mediated by: *

1 point

only endocytosis

both endocytosis and phagocystosis

both endocytosis and membrane fusion

only pinocytosis

Q12. RNA interference is mediated by both siRNA and miRNA. Which one of the following statement about them is NOT true. *

1 point

Both siRNA and miRNA are processed by DICER.

Both siRNA and miRNA usually guide silencing of the same genetic loci from which they originate.

miRNA is a natural molecule while siRNA is either natural or a synthetic one

miRNA, but not siRNA is processed by Drosha.

Q4. Predominant interactions between phospholipids that stabilize a biological membrane include *

1 point

hydrogen bonds and covalent interactions..

van der waal and ionic interactions.

hydrophobic interactions and hydrogen bonding.

covalent and hydrophobic interactions.

Q16. Which one of the following statements about receptor-enzyme is FALSE? *

1 point

A receptor-enzyme has an extracellular ligand binding domain, a trans membrane domain and an intracellular catalytic (enzyme) domain.

Many types of receptor enzymes are found in animals.

The signal transduction pathways of receptor-enzyme involve phosphorylation cascades.

Receptor-enzymes interact directly with intracellular G-proteins.

Q2. Penicillin acts as a suicide substrate. Which one of the following steps of catalysis does a suicide inhibitor effect? *

1 point

Q11. The -COOH group of cellular amino acids can form which of the following bonds inside the cell? *

1 point

Ether and ester bonds

Ester and amide bonds

Amide and ether bonds

Amide and carboxylic anhydride bonds

Q20. Sperm cell behavior during double fertilization in 'Arabidopsis' can be stated as follows. Identify the INCORRECT statement: *

0 points

Pollen tube bursts and discharges sperm cells.

Sperm cells produce pollen tubes and enter into female gametophyte.

One sperm nucleus fuses with the egg cell and the other fuses with the central cells.

All of the Above

Q9. E. Coli is being grown in a medium containing both glucose and lactose. On depletion of glucose, expression of beta-galactoside will *

1 point

remain unchanged

increase

decrease

initially decrease and then increase

Q19. The initial dorsal-ventral axis in amphibian embryos is determined by *

1 point

The point of sperm entry.

gravity.

the point of contact with the uterus.

genetic differences in the cells.

Q14. Which of the following bacteria has subcellular localization in lysosomes? *

1 point

Salmonella typhi

Streptococus pneumoniae

Vibrio cholarae

Mycobacterium tuberculosis

Q7. Histone decaetylase (HDAC) catalyses the removal of acetyl group from N-terminal of histones. Which amino acid of histone is involved in this process? *

1 point

Lysine

Arginine

Asparagine

Histidine

Q18. During development, if a cell has committed to a particular fate, it is said to be *

1 point

pluripotent

totiotent

determined

diffrentiated

Q8. Labelling of membrane spanning domain of any integral membrane protein in a given plasma membrane vesicle (without disrupting its structure) is successfully carried out by *

1 point

immunochemical methods.

metabolic labelling with radioisotopes.

hydrophobic photoaffinity labelling.

limited proteolysis followed by metabolic labelling.

Q17. Bones of vertebrates are derived from embryonic *

1 point

ectoderm

epiderm

mesoderm

endoderm

Q6. Lateral diffusion of proteins in membranes can be followed and diffusion rate calculated by *

1 point

Atomic force microscopy

Scanning electron microscopy

Transmission electron microscopy

FRAP

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