Unit 07: Cell Membrane (initial)
“This Knowledge Audit will gauge your understanding of the material for the "Cell Membrane" unit before instruction begins. Your teacher will use the information to modify, change and improve instruction as suggested by the results. Please answer each question accurately and honestly. You are scored for on time completion of the assignment, not how much you already know.”
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First Name *
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What period do you take IB Biology? *
Syllabus Statements
For each statement below, indicate your level of confidence and knowledge about the statement using the following scale:
1. Very poor: you've never heard of this topic or idea.
2. Poor: you've heard this, but couldn't tell share any detailed information about it.
3. Fair: you remember the basic information about this topic or idea.
4. Good: you remember details and examples about this topic or idea.
5. Very good: you could teach others about this topic or idea.
1.3.U1: Phospholipids form bilayers in water due to the amphipathic properties of phospholipid molecules *
Draw a simplified diagram of the structure of the phospholipid, including a phosphate-glycerol head and two fatty acid tails. Define hydrophilic and hydrophobic. Define amphipathic and outline the amphipathic properties of phospholipids. Explain why phospholipids form bilayers in water, with reference to hydrophilic phosphate heads and two hydrophobic hydrocarbon tails.
Very Poor
Very Good
1.3.NOS1: Using models as representations of the real world-there are alternative models of membrane structures *
Explain what models are and their purposes in science. Describe the observations and conclusions drawn by Gorter and Grendel in discovering the structure of cell membranes.
Very Poor
Very Good
1.3.S2: Analysis of evidence from electron microscopy that led to the proposal of the Davson-Danielli model *
Describe the observations and conclusions drawn by Davson and Danielli in discovering the structure of cell membranes.
Very Poor
Very Good
1.3.S3: Analysis of the falsification of the Davson-Danielli model that led to the Singer-Nicolson model *
Describe conclusions about cell membrane structure drawn from freeze-etched electron micrograph images of the cell membrane. Describe conclusions about cell membrane structure drawn from cell fusion experiments. Describe conclusions about cell membrane structure drawn from improvements in techniques for determining the structure of membrane proteins.. Compare the Davson-Danielli model of membrane structure with the Singer-Nicolson model.
Very Poor
Very Good
1.3.NOS2: Falsification of theories with one theory being superseded by another-evidence falsified the Davison-Danielli model *
Describe why the understanding of cell membrane structure has changed over time.
Very Poor
Very Good
1.3.S1: Drawing of the fluid mosaic mode *
Draw and label the structure of membranes. Include: Phospholipid bilayer. Integral proteins shown spanning the membrane. Peripheral proteins on membrane surface. Protein channels with a pore. Glycoproteins with a carbohydrate side chain. Cholesterol between phospholipids in the hydrophobic region. An indication of thickness (10nm)
Very Poor
Very Good
1.3.U2: Membrane proteins are diverse in terms of structure, position in the membranes and function *
State the primary function of the cell membrane. Contrast the structure of integral and peripheral proteins. List at least four functions (with example) of membrane bound proteins. Contrast the two types of transport proteins: pumps and channels.
Very Poor
Very Good
1.3.U3: Cholesterol is a component of animal cell membranes *
Identify the structure of cholesterol in molecular diagrams. Describe the structural placement of cholesterol within the cell membrane.
Very Poor
Very Good
1.3.A1: Cholesterol in mammalian membranes reduces membrane fluidity and permeability to some solutes *
Describe the function of cholesterol molecules in the cell membrane.
Very Poor
Very Good
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