High-performance materials are needed for structural applications, including in the rebuilding of areas ravaged by recent hurricanes, but cement production is responsible for 8% of global CO2 emissions, mainly due to the high temperature calcination of calcium carbonate during production.  The urgency for low carbon, inexpensive, and higher performance structural materials will require an MGI approach.  Efforts will need to connect understanding across time and spatial scales. New tools that can link modeling and analytical approaches to support materials design are needed. The design of these novel materials will need to incorporate a set of performance requirements that are critical for widespread adoption, and include considerations of feedstock supply chains, workability, set times, aesthetics, and cost.