Principles of Systemic Treatment of Cancer Quiz

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Created by Harman Toor
Edited by Dr. Paris Ingledew

A 47 year old female is being treated for breast cancer. The tumour was found to be 4 cm and locally advanced. The plan is to treat with chemotherapy before breast conserving surgery. This is an example of?

1 point

Maintenance chemotherapy

Palliative chemotherapy

Adjuvant chemotherapy

Neo-adjuvant chemotherapy

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Which of the following is true regarding the management of chemotherapy induced nausea and vomiting?

1 point

Eating large meals a few times a day is recommended

Neurokinin-1 receptor antagonists and glucocorticoids can be effective

Vestibular stimulation is commonly recommended to reduce nausea

Behavioural therapies are not helpful for anticipatory emesis

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A 67 year old male is being treated for prostate cancer with a medication which is causing a side effect of hot flashes but no scalp alopecia. The medication likely belongs to which therapeutic class?

1 point

Immunotherapy

Hormonal Therapy

Traditional Chemotherapy

Targeted Therapy

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A 47 year old male is receiving a second cycle of chemotherapy for pancreatic cancer. He is feeling fatigued, lethargic, and is experiencing chills. His oral temperature is 38.1 °C for the last hour. What lab test would confirm your suspected diagnosis?

1 point

C Reactive Protein

CBC with differential

Creatinine

Absolute Eosinophil Count

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Which class of cancer therapy is peripheral neuropathy commonly associated with?

1 point

Microtubule Inhibitors

Immunotherapy

Hormone Therapy

Targeted Therapy

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The dosing for most traditional systemic chemotherapies is based on:

1 point

Actual Body Weight

Body Surface Area

Ideal Body Weight

Empiric Dosing

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Which class of chemotherapy is M phase specific?

1 point

Vinca Alkaloids

Antimetabolites

Topoisomerase Inhibitors

Alkylating Agents

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72 year old female is found to have estrogen receptor negative, progesterone receptor negative, human epidermal growth factor 2 (HER-2) receptor positive breast cancer. Which of the following is a possible targeted or hormonal treatment?

1 point

Tamoxifen

Leuprolide

Trastuzumab

Imatinib

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Which of the following chemotherapies is known to be associated with pulmonary toxicity?

1 point

Bleomycin

Vincristine

Paclitaxel

Capecitabine

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Hemorrhagic cystitis and bladder fibrosis is associated with which of the following?

1 point

Methotrexate

Cyclophospamide

Doxorubicin

Tamoxifen

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