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SHRI CHHATRAPATI SHIVAJI COLLEGE, OMERGA
Msc Chemistry , Medicinal chemistry Sem. IV
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1. Medicinal chemistry is interdisciplinary science of .....
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1 point
Physics and chemistry
Math & biology
Chemistry & Biology
Chemistry & Physical chemistry
2. In medicinal chemistry ....
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1 point
discovery of compound
development of compound
synthesis & identification of compound
All of above
3. Drug words meaning is .....
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1 point
Dry herb
compound
Cocane
None
4. Drug define as ....
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1 point
Increase health
Decrease health
Prevention & Cure disease
None of above
5. What is long form of WHO?
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1 point
work home office
world health organisation
what how our
none
6. Drug should be have
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1 point
toxic
non toxic
side effects
more toxic
7. Drug having following characteristics.
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1 point
not injured cells
act as a effective & safety
Non toxic
All above
8. What is prodrugs?
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1 point
Derivatives of bioactive molecules
chemical compound
Acetic acid
Phenol
9. What types of drugs observed?
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1 point
acid & base drug
hard & soft Drug
Phenolic drug
none
10. The drug is non metabolizable are called ......
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1 point
acid drug
soft drug
hard base
hard drug
11. The drug is metabolizable are called ......
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1 point
soft base
soft drug
hard phenol
none
12. what advantage of soft drug ?
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1 point
avoid pharmacological active compound
elimination interaction
increases potency
All above
13. What is metabolite?
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1 point
Compd formed in Or necessary for metabolism
Acid compd
Base compd
none of above
14. Which compds are called Antagonists?
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1 point
inhibits essential metabolite action
biological action
chemical compd
acid phenol compd
15. Potency of drug means ...
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1 point
nature
effect
M.pt.
biological activity
16. What is Isosterism?
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1 point
same
m.pt
.
diff. boiling pt.
same nature
same number & arrangement of electron
17. Pharmacophore means ......
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1 point
Functional group responsible for medicinal activity
Functional group decreases activity
Losses biological activity
Both 1 & 2
18. Bioisosterism means .....
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1 point
same property
diff. property
same biological activity
none
19. What is Lead compound?
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1 point
chemical compd
starting point compd
last compd
none
20. Sources of lead compound?
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1 point
Flora & Fanna
micro organisms
marine chemistry
all above
21. LD50 means .....
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1 point
minimum dose to death 50% animals
more dose for live 50% animal
lost drug 50
none
22. ED50 means ......
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1 point
Early drug 50
Desired effect in 50% animal
Both 1 & 2
none
23. Which factors affects bioactivity?
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1 point
lipophilicity
ionisation
partition
coefficient
all above
24. Steric effect role in bioactivity of drug.
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1 point
Affects bioactivity
not affects
low affects
none
25. Occupancy theory based on
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1 point
Drug
compd
receptor
drug-receptor
26. Rate theory based on
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1 point
drug
receptor
Association & dissociation of receptor
bacteria
27. Induced fit theory based on
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1 point
drug
receptor
protein
activation & deactivation of enzames
28. SAR means .....
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1 point
simple analysis relation
some animal relation
structure activity and relationship
none of above
29. Hanch equation related to .....
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1 point
physicochemical properties
odour & color properties
physical properties
chemical properties
30. Pharmacokinetics means ......
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1 point
study of drug
kinetic process
Drug study of action & metabolism
None
31. Which steps are observed in Pharmacokinetics.
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1 point
absorption, distribution
distribution, elimination
absorption, distribution, elimination
elimination, distribution
32. Pharmacodynamics defined as
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1 point
study of drug effects & complete action effects
drug absorption study
drug receptor concept
All above
33. Drugs which inhibits growth of any micro organisms are called .....
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1 point
compd
antipyretics
antimetabolites
tranquilizers
34. Who first scientist states about malaria?
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1 point
Ronald Ross
Albert Einstein
Newton
C V Ramman
35. Malaria disease causes due to .....
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1 point
Dogs
Cats
Rats
Mosquito
36. What is Antibiotics?
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1 point
stimulate bacteria
destroy micro-organisms
decreases activity
none of above
37. Which is Anti-inflammatory drug?
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1 point
Ibuprofen
cis platin
Troglitazone
Verapamil
38. Antidiabetics drugs means
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1 point
drug used for decreases sugar level
drug used for brain treatment
drug used for heart disease
drug used for increase sugar level
39. Anesthetic drugs means ....
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1 point
used for pain increase
used for blood
liver disease
Insensitivity to pain
40. Anti hypertensive drugs means ......
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1 point
used against heart
used against brain
used against lungs
used against liver
41. COVID-19 means
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1 point
corona virous disease 2019
common virous drug 2019
crown various dieses 2019
none
42. COVID-19 is ........ infected diesease
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1 point
bacteria
micro-organisms
virus
fungi
43. Atenolol drug used for
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1 point
Anti-malaria
antibiotic
anti-hypertensive
antiviral
44. Chloramphenicol is ...... drug.
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1 point
antibacterial
antiviral
anesthetic
antibiotic
45. Cis- platin is ..... drug
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1 point
anti biotic
anticancer
antiviral
antibiotic
46. Ketamine used for .......
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1 point
antimalari
anti HIV
anesthecia
antibiotic
47. Which is the different class drug in following
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1 point
ketamine
lidocaine
procaine
acyclovir
48. Paracetamol is used as .....
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1 point
antipyretics
antihypertensive
antibiotic
antidiabetics
49. Sulfamethoxazole is used as ....
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1 point
antibiotics
anesthetics
antiviral
none
50. Diclofenac sodium used for .....
1 point
antihistamine
anti-inflammatory
antipyretics
antidiabetics
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