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Animal Subjects Certification Exam
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As a member of a lab, what is the required minimum amount of times you have to observe animals on your protocol?
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1 point
3 times weekly
4 times weekly
That is dependent upon what is specifically described in my approved protocol
5 times weekly
Any serious or continuing non-compliance with your protocol could result in the following (please select all that apply):
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1 point
Revocation of animal use privileges
Suspension of the protocol
Retraining
Reporting to The Office of Laboratory Welfare (OLAW) and the USDA
Loss of funding
Loss of NYU’s Animal Welfare Assurance
Required
If a procedure is deemed to be painful in humans, it should be assumed that:
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1 point
Animals experience pain differently and may not require the same degree of pain-relief as humans typically do
The procedure will be painful to animals unless scientifically proven otherwise
The procedure should therefore not be conducted with animals
The procedure will not be approved by the IACUC
Understanding that all substances administered to an animal must be approved by the IACUC and non-expired, the appropriate way to handle expired controlled substances in the lab would be to:
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1 point
Dispose of the expired drug and let the lab manager know that more of that drug is needed
Discontinue use of the expired drug once the lab obtains more of the drug
Contact OVR
Discontinue use of the expired drug, appropriately log the units or volume remaining, label the vial or box as expired, place on a separate shelf in the drug locker, and contact RLS for drug surrender
There are certain animals used in research that are considered “USDA-covered species.” This means:
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1 point
That under the Animal Welfare Act, those animals require oversight by the USDA
That under the Animal Welfare Act, those animals require covered animal housing areas
That under the Animal Welfare Act, those animals require additional oversight by NYU
That if you have those animals at your institution, they are cared for by the USDA
In order to avoid research animals experiencing any undue stress, it is important to:
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1 point
Practice appropriate handling techniques
Be mindful of one’s own conduct within each animal housing and testing area, including speaking volume
Avoid use of any non-approved cleaning materials
All of the above
You are at work after hours (after 5pm weekdays or on the weekend) and discover one of your animals is unwell. What action do you take?
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1 point
Wait until next business day to report it
Try to treat it yourself and if unsuccessful, notify OVR
Send an email to OVR
Call the Veterinarian on-call directly
By law, an inspector has the right to enter animal housing areas, but not laboratories where animal studies are conducted because of the disruption it could cause.
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1 point
True
False
Humane death for a research animal by an approved method that induces rapid loss of consciousness and death with minimum pain, discomfort or distress is known as:
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1 point
Animal termination
Merciful goodbye
Euthanasia
Sacrificial ending
When inspecting your lab, the IACUC members will expect to see (please select all that apply):
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1 point
Non-perishable food given to animals is stored in sanitizable containers that are labeled with the date food was opened and date of expiration
Spaces where procedures are performed are clean and organized
Training records are complete, up to date and readily available
PI or their designee(s) can answer protocol-related questions
Lab fridges where perishable food and drugs are stored are clean and contents are appropriately labeled
Drugs and materials administered to animals are not expired
Required
A scientist may begin their research before receiving IACUC protocol approval if they have conducted similar research in the past.
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1 point
True
False
I should have full access to protocols that I am listed as having animal-related responsibilities on.
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1 point
True
False
You wish to obtain a new mouse line from another lab to breed with the mice that your lab is currently approved for. What is needed?
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1 point
Protocol approval for the use of breeding
Protocol approval for the transfer of animals
Protocol approval for using the new line
All of the above
Which of the following changes in animal use procedures could affect animal welfare and therefore must be considered a significant protocol change?
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1 point
Changing or adding analgesia or anesthetic on veterinary recommendation
Change in sex of animal to be used
Addition of survival surgery
Additional noninvasive sampling
Based on requirements from NIH and the USDA, all animal use areas must be reviewed _______ by the IACUC.
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1 point
Each year
Twice per year
Every 3 months
Every 2 years
A surgery that does not penetrate or expose a body cavity, and does not have the potential to induce permanent impairment of physical or physiologic function is considered:
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1 point
Major surgery
Minor surgery
Personal safety risks can result from cross-contamination and ingestion. Therefore, when in an animal use area, I must:
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1 point
Avoid eating and drinking
Ensure that any beverage I bring into the space has a lid
Ensure I only place my food containers on sanitized surfaces
Ensure I only use clean utensils and sanitize my hands upon leaving
What methods are available to scavenge Isoflurane gas?
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1 point
A. Room air exhaust
B. Fume hood
C. Activated charcoal canister
D. PPE
E. Hepa-filtered changing station
F. Both A and C
G. Both C and D
H. Both B and C
I. Both D and E
Water restriction protocols have the potential for causing distress to research animals and therefore, the least restriction that will achieve the scientific objectives of the study should be used.
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1 point
True
False
If you see something in your lab or the facility that causes you concern regarding animal welfare, you should:
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1 point
Tell your PI
Contact a member of the Institutional Animal Care and Use Committee or make a report online
Tell the Chair of your department
Tell a member of your lab
Your lab decides you want your animal to be fed a different diet and receive different enrichment to that provided by OVR. How do you implement those changes?
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1 point
A. No special steps are needed; simply make the change
B. Ask permission from OVR
C. First submit a protocol amendment to describe and justify the changes
D. Label the cage to indicate the special husbandry required
E. B, C, and D
F. C and D
PPE stands for Personnel Protective Equipment, which must be worn when entering animal rooms in the facilities. PPE includes (please select all that apply):
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1 point
Hair cap
Goggles
Face mask
Gown
Rubber gloves
Booties
Sandals
Required
What is the difference between an experimental endpoint and a humane endpoint?
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1 point
An experimental endpoint is when the scientific aims and study objectives have been met, whereas a humane endpoint is one that is necessary based on an unexpected or adverse event to prevent pain or distress in an experimental animal
An experimental endpoint is one that is necessary based on an unexpected or adverse event to prevent pain or distress in an experimental animal whereas a humane endpoint is when the scientific aims and study objective have been met
An experimental endpoint is the endpoint described to the IACUC and the humane endpoint is what the lab does in case of emergency
An experimental endpoint is everything described by the PI on a particular study whereas a humane endpoint is the piece that relates specifically to animals
As a regulatory requirement, how often do research animals need to be observed?
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1 point
No less than weekly
Daily
Five days a week not counting weekends
Twice a week
When transporting research animals from the vivarium to your lab, it is essential that only the freight elevators and approved routes of transportation be used.
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1 point
True
False
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