Infection Protection For The First 1000 days Of Life: Role of L. reuteri DSM 17938 On Microbial Communication Of Mother To Foetus
L. reuteri one of the most well researched probiotic species
To date 229 clinical trials with BioGaia's human strains of L. reuteri DSM 17938 have been performed in 18,536 individuals of all ages. The intake of L. reuteri DSM 17938 has been safe and not associated with any adverse events.

* L. reuteri DSM 17938 is derived from L. reuteri ATCC 55730. By removal of two plasmids carrying tet (W) tetracycline and lnu (A)lincosamide resistance genes, the new daughter strain is FREE from potentially transferable resistance genes.
Böttcher MF (2008) L. reuteri DSM 17938 increases anti-inflammatory cytokine in mother's colostrum
• The colostrum content of the cytokine TGF-beta 2 was significantly reduced while its content of the anti-inflammatory cytokine IL-10 increased.

• Supplementation with L. reuteri DSM 17938 during late pregnancy reduces breast milk levels of TGF‐β2, and low levels of this cytokine are associated with less sensitization and possibly less IgE‐associated eczema in breast‐fed infants.
Abrahamsson (2007) L. reuteri DSM 17938 reduced the frequency of IgE-associated eczema and sensitisation to food allergens in children
• Primary outcome was allergic disease, with or without positive skin prick test or circulating IgE to food allergens.

• Treated infants had less IgE-associated eczema at 2 years of age, especially those with allergic mothers. The lower incidence of allergic sensitisation in the L. reuteri DSM 17938 group implies that these children possibly run a reduced risk of respiratory allergy later in life.
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BioGaia L. reuteri DSM 17938, The only probiotic with scientific evidence in infantile colic.
Dr. Flavia Indrio (Department of Paediatrics University of Bari, Italy)
"Colic, constipation, and regurgitation can be prevented through early intervention with L. reuteri DSM 17938"

Dr. Flavia Indrio recommend microbial transfer from mom to newborns for at least 1000 days from conception to 2 years after birth for the life-long health of the child.
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