GPAT (19) Pharmaceutical Chemistry Test-1

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Retention hyperbilirubenamia is caused due to

1 point

Choleric jaundice

Non clearance of bilirubin

Reflux of bilirubin into blood stream

Over production of bilirubin

Clear selection

What will be the Heat of vaporisation of 1 mole of water, when it has the entropy change (∆S) of cal/mole.deg (at 25°C) ?

1 point

1.408 cal/mole

10489 cal/mole

8465 cal/mole

880 cal/mole

Clear selection

1 point

Esmolol

Betaxolol

Metoprolol

Bisaprolol

Clear selection

The following ACE inhibitor used in treating cardiovascular disorder is synthesized from the natural amino acids L-alanine and L-proline :

1 point

Ramipril

Enalapril

Insmopril

Captopril

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The infra-red absorption peaks of Nujol is due to vibrations involving

1 point

S-hstr and S-hdef

S-hstr and O-hdef

C - hstr and C-hdef

N-hstr and N-hdef

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Permitted tolerance limit for a 100mL class B volumetric flask and 1000 mL class B volumetric flask according to BS 1792 specifications respectively are…………………mL

1 point

0.15 and 0.80

0.80 and 0.30

1.00 and 10.00

0.15 and 1.5

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1 point

237 nm

215 nm

241 nm

240 nm

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One of the following is a most commonly used protecting group for amines :

1 point

Para Methyl benzyl (PMB)

t-Butyloxy carbonyl (t-BOC)

Methoxy methylene (MOM)

Tetra hydro pyranyl oxy (THP)

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Choose the correct sequence of process during Atomization in atomic absorption spectroscopy

1 point

Desolvation → Nebulization → Dissociation → Volatilization → Ionization

Nebulization → Desolvation → Volatilization → Dissociation → Ionization

Desolvation → Nebulization → Volatilization → Dissociation → Ionization

Nebulization Volatilization → Desolvation → Dissociation → Ionization

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Which among the following carrier gases has the highest thermal conductivity?

1 point

Nitrogen

Oxygen

Helium

Compressed Air

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Phase solubility Analysis curve is not a good tool for :

1 point

Complex formation

Bioavailability determination

Polymorph detection

Impurity detection

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1 point

Curtius Rearrangement

Clemmensen reduction

Wolf-Kishner reduction

Wolf-Rearrangement

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Which of the following inactive clotting factor is activated by the vitamin-K as a co-enzyme?

1 point

I, II, III, IV

II, V, IX, X

II, V, VI, VIII

II, VII, IX, X

Clear selection

Identify the molecule which will not exhibit Dipole moment?

1 point

Carbon dioxide

Carbon monoxide

Chloroform

Ammonia

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The following combination of drugs are used in treating severe travelers diarrhoea :

1 point

Pyrimethamine and sulfadiazine

Trimethoprim and sulfadiazine

Pyrimethamine and sulfamethoxazole

Trimethoprim and sulfamethoxazole

Clear selection

1 point

Willgerodt rearrangement

Bamford steven reaction

Darzen's glycidic synthesis

Bayer villiger rearrangement

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Amylopectin, a component of starch gives…………colour with iodine

1 point

No colour

Green

Blue

Red-purple

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Anti addition of bromine to trans-2-butene yields :

1 point

Enantiomer and racemic mixture

Only racemic mixture

Only enantiomers

Only meso compounds

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Conversion of aryldiamnium chloride to arylchloride can be achieved in the presence of:

1 point

Copper (II) chloride

Copper (I) chloride

Sodium chloride

Calcium chloride

Clear selection

Von Gierke's glycogen storage disease is due to defect of which enzyme :

1 point

Phosphofructokinase

Glucosyl 4 - 6 transferase

Glycogen phosphorylase

Glucose-6-phosphatase

Clear selection

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