Precision Diagnosis and Tolerance Induction in Children with Immediate-Type Wheat Allergy
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香港中文大學醫學院兒科學系正進行一項有關「兒童即時小麥過敏的精準診斷和耐受性誘導研究」的臨床試驗。
研究將分為兩個階段:
第一階段 精準診斷小麥過敏(診斷)
針對 1-17 歲,並有攝入小麥/麩質後四小時內出現過敏反應史
** 受試者需到訪沙田威爾斯親王醫院進行過敏測試,包括抽取血液進行過敏血液測試、皮膚點刺測試、雙盲對照口服激發測試 DBPCFC(需分兩天進行)
第二階段 小麥口服免疫治療(脫敏)
經小麥口服激發測試證實對小麥過敏的 3-17 歲受試者
** 受試者將被安排進行為期12個月的小麥口服脫敏治療(低劑量或標準劑量),並在治療結束後進行兩次跟進到診
有意參加的人士請填妥以下資料,我們會盡快聯絡您。 ** 注意:完成此問卷並不代表您/您的孩子已完成招募程序。研究人員將稍後聯絡您作跟進。
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CUHK Paediatrics is now conducting a clinical trial study of "Precision Diagnosis and Tolerance Induction in Children with Immediate-Type Wheat Allergy".
The research will be conducted in two stages:
STAGE 1 Precision Diagnosis of Wheat Allergy (Diagnosis)
For individuals aged 1-17 with a history of allergic reactions within four hours after consuming wheat/gluten
**Subjects are required to visit Prince of Wales Hospital for allergy diagnostic tests, including blood sampling for allergy blood test, skin prick test, and double-blind placebo-controlled oral food challenge (DBPCFC)(to be conducted over two days)
Phase 2 Wheat Oral Immunotherapy (OIT)
For 3-17 year-old subjects who are confirmed to be allergic to wheat through wheat DBPCFC
**The subjects will be scheduled to receive wheat oral immunotherapy for a period of 12 months (low dose or standard dose), and will undergo two follow-up visits after the treatment is completed
Please complete the form below if you are interested. You will be contacted soon. ** Completing this questionnaire does not mean that you / your child has completed the recruitment process. The research staff will contact you later for follow-up.