Unit 15: Genes and Genomes (final)
“This final Knowledge Audit will gauge your understanding of the material for the "Genes and Genomes" unit after instruction has ended. Your teacher will use the information to see where you have grown and what you still feel you need to improve on. Please answer each question accurately and honestly."
Last Name *
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First Name *
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What period do you take IB Biology? *
Syllabus Statements
For each statement below, indicate your level of confidence and knowledge about the statement using the following scale:
1. Very poor: you've never heard of this topic or idea.
2. Poor: you've heard this, but couldn't tell share any detailed information about it.
3. Fair: you remember the basic information about this topic or idea.
4. Good: you remember details and examples about this topic or idea.
5. Very good: you could teach others about this topic or idea.
3.1.U1: A gene is a heritable factor that consists of a length of DNA and influences a specific characteristic *
Define gene.
Very Poor
Very Good
3.1.U2: A gene occupies a specific position on a chromosomes *
Define gene locus.
Very Poor
Very Good
3.2.S1: Use of databases to identify the focus of a human gene and its polypeptide product *
Search NCBI or OMIM for a given gene. Determine the gene locus, abbreviated gene name, and description of the gene.
Very Poor
Very Good
3.1.A2: Comparison of the number of genes in humans with other species *
State the number of genes in the human genome. Describe the relationship between the number of genes in a species and the species complexity in structure, physiology and behavior.
Very Poor
Very Good
3.1.S1: Use of a database to determine differences in the base sequence of a gene in two species *
Explain why cytochrome oxidase 1 is often used to assess the differences in the base sequences of a gene between two species. Use NCBI to BLAST search for COX1 sequences for different species. Use a computer software tool to create an alignment of the gene sequences between different species. Outline information that can be determined given gene sequence alignment data.
Very Poor
Very Good
7.3.NOS: Developments in scientific research follow improvements in computing- the use of commuters has enabled scientists to make advances in bioinformatics applications such as locating genes within genomes and identifying conserved sequences *
Define bioinformatics. Outline why computers are necessary for genome analysis. List seven species for which the entire genome has been sequenced.
Very Poor
Very Good
3.1.U3: The various specific forms of a gene are alleles *
Define allele. List two examples of genes with multiple alleles. State a similarity between alleles of the same gene
Very Poor
Very Good
3.1.U4: Alleles differ from each other by one or only a few bases *
State the difference between alleles of the same gene.
Very Poor
Very Good
3.1.U5: New alleles are formed by mutation *
State the source of new alleles of a gene. Describe a base substitution mutation.
Very Poor
Very Good
3.4.U10: Radiation and mutagenic chemicals increase the mutation rate and can cause genetic diseases and cancer *
State two factors that can increase the mutation rate. Outline the effects of gene mutations in body cells and gamete cells.
Very Poor
Very Good
3.4.A4: Consequences of radiation after nuclear bombing of Hiroshima and accident at Chernobyl *
Outline the effects of radiation exposure after nuclear exposure at Hiroshima and Chernobyl.
Very Poor
Very Good
3.1.U6: The genome is the whole of the genetic information of an organism *
Define genome. State the size in base pairs of the human genome.
Very Poor
Very Good
3.2.A2: Comparison of genome size in T2 phage, Escherichia coli, Drosophila melanogaster, Homo sapiens, Paris japonica *
Describe the relationship between the genome size of a species and the species complexity in structure, physiology and behavior.
Very Poor
Very Good
3.1.U7: The entire base sequence of human genes was sequenced in the Human Genome Project *
Define “sequence” in relation to genes and/or genomes. State the aim of the Human Genome Project. Outline two outcomes of the Human Genome Project.
Very Poor
Very Good
3.1.NOS: Developments in scientific research follow improvements in technology-gene sequencers are used for the sequencing of genes *
Outline the technological improvements that have sped the DNA sequencing process. Determine a DNA sequence from an electropherogram.
Very Poor
Very Good
7.1.A3: Use of nucleotides containing dideoxyrubonucleic acid to stop DNA replication in preparation of samples for base sequencing *
Outline the process of DNA sequencing, including the role of chain terminator nucleotides, fluorescence, and electrophoresis.
Very Poor
Very Good
Any questions you want to ask before tomorrow's quiz?
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April is almost over- so it is time for April compliments! Give someone in class a shout-out for being awesome. All compliments will be anonymous.
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