In silico pharmacokinetics involves using computer simulations and modeling techniques to predict the absorption, distribution, metabolism, excretion and toxicity (ADMET) of drugs within the human body. This approach helps in understanding how a drug behaves in the system, aiding in the optimization of drug design and development. By simulating pharmacokinetic profiles, researchers can make informed decisions about drug dosing, efficacy, and safety, ultimately streamlining the drug development process and reducing the need for extensive in vivo testing.