Pharmaceutics 3 || Mid

JavaScript isn't enabled in your browser, so this file can't be opened. Enable and reload.

Pharmaceutics 3 || Mid

Skin permeation may be tested in vitro using *

1 point

a.Drug concentration plasma levels

b.Franz diffusion cell

c.All methods are used for in vitro studies

d.Tape-stripping method or sking biopsis

The face adhesive of patches are called so because they are usually applied to the face *

1 point

a.True

b.False

All of the following arw advantages of using TDDSs, EXCEPT *

1 point

a.Provides controlled plasma levels of very potent drugs

b.Provides an economical formulations

C.Avoids chemically hostile GI environment

d.Allows effective use of drugs with short biological half life

e.Allow administration of drugs with low theraputic window

One of the following consideration is NOT TRUE when using TDDS *

1 point

a.Patches should not be placed at a site where it will not be rubbed off by clothing or movement

b.Patches should be applied to clean , dry skin that is relatively free of hair and not oily, irritant , inflamed , broken or callused

c.A ptient should be advised of the importance of using the recommended application site writtenon the package and rotating locations within the site

d.Patches can be cut into smaller size needed

Drug-in-adhesive patches composed of *

1 point

a.Backing membrane, polymer matrix , adhesive layer and release liner

b.Backing membrane Drug reservoir , rate controlling membrane , adhesive

c.Backing membrane ,drug reservoir , adhesive liner and release liner

d.Backing membrane , adhesive layer and release liner

Which of the skin modifications work as a penetration enhancer *

1 point

a.Water which causing disruption phospholipids

b.laser ablation

c.Ethanol causing disruption of phospholipids

d.Localized heating

e.Ethanol causing hydration of skin

One of the following preperations is not intented for topical use

1 point

a.Ointment

b.Insulin pen

c.Cream

d.Gel

Clear selection

The followimg dressing is used to facilitate autolyticdebridment in necrotic wounds and to maintain moist healing environment on clean granulating wounds *

1 point

a.Alginate dressings

b.Hydrocolloid dressing

c.Foam dressings

d.Hydrogel dressing

Polybase is a *

1 point

a.Absorption base

b.water soluble ointment base

c.Hydrocabon base

The ointment base that is emollient and endure longest on the skin for hours is *

1 point

a.Oleaginous bases

b.Water removable bases

c.Water miscible base

Creams are less suscetable than ointments to microbial contamination *

1 point

a.True

b.False

Paste is easily spread on application area attributed to its high content of fine powders *

1 point

a.True

d.False

One of the following is NOT TRUE regarding Drug in matrix patches *

1 point

a.Drug is embedded in a polymer matrix to control and prolong its release

b.Drug release is controlled by a rate controlling membrane

c.More drug may be incorporated compared to drug in adhesive patches

d.Typically produced as largw sheets that are later cut into smaller patches

e.All choices are true

The most suitable way to incorporate a course insoluble powder into a molten base is by *

1 point

a.Fusion

b.Trituration

c.Levigation

A suitable discaed data for an extemporaneously prepared ointment would be

1 point

a.2 weeks

b.3 months

c.21 days

d.14 days

Clear selection

Creams are always water-in-oil emulsion *

1 point

a.True

b.False

Keloid and other scars may result from excess collagen production during *

1 point

a.Migration

b.Proliferation of new tissue

c.Remodeling

d.Inflammation

Before you use a transdermal patches you should apply lotion at the application site to increase dryness and absorbtion *

1 point

a True

b.False

On of the followimg based is non-washable ointment base *

1 point

a.Water removable base

b.Polybase

c.Hydrocarbon base

Semisoild preparations must be medicated only *

1 point

a.True

b.False

The surfactant in creams allows better skin penetration than in ointments *

1 point

a.True

b.False

The proper primary package for ointment is *

1 point

a.Card box

b.Collapsible glass tube

c.Glass bottles

d.Wide mouth jars

Which of thr following ointment bases has the highest occlusive properties *

1 point

a.Water-in-oil emulsion bases

b.Oil-in-water emulsion bases

c.Oleaginous bases

d.Water-soluble bases

Regarding transdermal demivery system *

1 point

a.They are intended for drug delivery to the epidermis

b.They are intended for drug delivery to the dermis

c.They are intended for intramuscular drug delivery

d.They are intended for systemic drug delivery

Which of the following ointment bases can be most easily removed with water *

1 point

a.Water-in-oil emulsion bases

b.Oleaginous bases

c.Anhydrous absorption bases

d.Oil-in-water emulsion bases

Which of thr following factors will enhabce drug permeation through the skin *

1 point

a.Occlusion

b.Log P more than 4

c.Reducing drug concentration in the vehicle

d.High affininty between the drug and the vehicle

Absorption of a drug from a suppository base might not avoid hepatic first pass metabolism if *

1 point

a.Absorption occurs near the superior rectal vien

b.Non of the above

c.Absorption occurs near the middle rectal vein

d.Asorption occure near the inferior rectal vein

Advantages of the transdermal delivery system include *

1 point

a.Better patient compliance

b.Extended drug release

c.All the options are true

d.Avoid first pass effect

Penetration enhancer such propylene glycol work by *

1 point

a.Increase drug concentration in the skin (act as solvent)

b.All options are true

c.Increasing skin permeability irreversibly

d.Increasing fluidity of membrane lipids

The easiest patches to manufacture are *

1 point

a.Drug-in-adhesive patches

b.Drug-in-matrix patches

c.Reservoir patches

d.All of the options are true

The principle barrier against transdermal permeation is *

1 point

a.The stratum corneum

b.The subcutaneous fat

c.The dermis

d.The epidermis

Ideal properties fatty suppository base include *

1 point

a.High iodine value

b.High acid value

c.Non toxic and Non irritating

d.Large difference between meltimg and solidification points

Submit

Clear form

Forms

This content is neither created nor endorsed by Google.