H3: Choose only one answer

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For topic Myeloproliferative disorders
By Dr Tamer Soliman

1. Repeated phlebotomy in patients with polycythemia vera (PV) may lead to the development of: *

1 point

A. Folic acid deficiency

B. Sideroblastic anemia

C. Iron deficiency anemia

D. Hemolytic anemia

2. In essential thrombocythemia, the platelets are: *

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A. Increased in number and functionally abnormal

B. Normal in number and functionally abnormal

C. Decreased in number and functional

D. Decreased in number and functionally abnormal

3. In myelofibrosis, the characteristic abnormal red blood cell morphology is that of: *

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A. Target cells

B. Schistocytes

C. Teardrop cells

D. Ovalocytes

4. PV is characterized by: *

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A. Increased plasma volume

B. Pancytopenia

C. Decreased oxygen saturation

D. Absolute increase in total red cell mass

5. Features of secondary polycythemia include all of the following except: *

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A. Splenomegaly

B. Decreased oxygen saturation

C. Increased red cell mass

D. Increased erythropoietin

6. The erythrocytosis seen in relative polycythemia occurs because of: *

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A. Decreased arterial oxygen saturation

B. Decreased plasma volume of circulating blood

C. Increased erythropoietin levels

D. Increased erythropoiesis in the bone marrow

7. In PV, what is characteristically seen in the peripheral blood? *

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A. Panmyelosis

B. Pancytosis

C. Pancytopenia

D. Panhyperplasia

8. 9. The leukocyte alkaline phosphatase (LAP) stain on a patient gives the following results: 10(0) 48(1+) 38(2+) 3(3+) 1(4+) : Calculate the LAP score. *

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A. 100

B. 117

C. 137

D. 252

9. CML is distinguished from leukemoid reaction by which of the following? *

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A. CML: low LAP; leukemoid: high LAP

B. CML: high LAP; leukemoid: low LAP

C. CML: high WBC; leukemoid: normal WBC

D. CML: high WBC; leukemoid: higher WBC

10. Which of the following occurs in idiopathic myelofibrosis (IMF)? *

1 point

A. Myeloid metaplasia

B. Leukoerythroblastosis

C. Fibrosis of the bone marrow

D. All of these options

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