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EP.47 System Down: The Pharmacy Under Siege
Hospital Pharmacy Operations
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What is the primary clinical risk of potassium chloride when administered intravenously in excess?
10 points
a) Respiratory depression
b) Cardiac arrhythmias
c) Renal failure
d) Neurotoxicity
Clear selection
What ECG change is most indicative of hyperkalemia?
10 points
a) Shortened PR interval
b) Flattened T waves
c) Peaked T waves
d) ST-segment depression
Clear selection
Which medication could exacerbate hyperkalemia when administered alongside potassium chloride?
10 points
a) Furosemide
b) Losartan
c) Atorvastatin
d) Hydrochlorothiazide
Clear selection
Which strategy is most effective for preventing unauthorized access to high-alert medications like potassium chloride?
10 points
a) Limiting physical access to supply rooms
b) Increased staffing levels in pharmacies
c) Mandating written inventory logs
d) Reducing staff use of automated systems
Clear selection
What immediate treatment is indicated for potassium chloride overdose with signs of cardiac toxicity?
10 points
a) Naloxone administration
b) Calcium gluconate infusion
c) Sodium bicarbonate bolus
d) Furosemide injection
Clear selection
Which of the following is NOT a contributing factor to the diversion of controlled substances in hospitals?
10 points
a) Manual override options
b) Lack of automated alerts
c) Regular inventory audits
d) Poor staff training
Clear selection
What is the primary role of pharmacists in managing high-alert medications?
10 points
a) Administering medications directly
b) Conducting patient education sessions
c) Monitoring storage and safety protocols
d) Supervising inventory audits
Clear selection
Which of the following is a known antagonist to potassium-induced cardiac arrhythmias?
10 points
a) Calcium chloride
b) Magnesium sulfate
c) Lidocaine
d) Amiodarone
Clear selection
What is the key principle of the "tall man lettering" strategy?
10 points
a) Highlight high-risk patients.
b) Distinguish look-alike, sound-alike drugs.
c) Identify critical-dose medications.
d) Ensure proper refrigeration.
Clear selection
Which scenario best describes a sentinel event?
10 points
a) A routine medication refill error.
b) A patient receiving potassium chloride via IV without monitoring.
c) A patient requiring an extended hospital stay.
d) Misfiled records in a pharmacy database.
Clear selection
What best describes the pharmacological action of potassium chloride in the cardiac system?
10 points
a) Enhances cardiac output.
b) Alters resting membrane potential.
c) Inhibits atrioventricular conduction.
d) Promotes coronary vasodilation.
Clear selection
Which organization provides best-practice guidelines for handling high-alert medications?
10 points
a) FDA
b) CDC
c) ISMP
d) WHO
Clear selection
What is the recommended action when a medication error is identified in real-time?
10 points
a) Notify hospital administration immediately.
b) Correct the error and document it.
c) Continue treatment and assess later.
d) Ignore it if patient harm is not apparent.
Clear selection
Which is the most likely adverse effect of untreated hyperkalemia?
10 points
a) Hypertension
b) Myocardial infarction
c) Seizures
d) Cardiac arrest
Clear selection
What is the most critical step when documenting medication discrepancies?
10 points
a) Assigning blame to staff members.
b) Ensuring tamper-proof storage of evidence.
c) Completing reports in a timely manner.
d) Identifying systemic contributors.
Clear selection
Which type of technology most effectively prevents medication errors related to dosage?
10 points
a) Electronic health records
b) Automated dispensing cabinets
c) Barcode scanning systems
d) Smart infusion pumps
Clear selection
In the case of high potassium levels, which medication can facilitate potassium excretion?
10 points
a) Spironolactone
b) Albuterol
c) Insulin and glucose
d) Sodium bicarbonate
Clear selection
Which protocol best addresses systemic vulnerabilities in hospital pharmacies?
10 points
a) Increasing staff-to-patient ratios.
b) Implementing real-time surveillance systems.
c) Mandating manual overrides for emergencies.
d) Conducting daily team briefings.
Clear selection
What is the most effective way to verify the accuracy of pharmacy inventory logs?
10 points
a) Cross-checking with manual paper logs.
b) Using automated software audits.
c) Conducting surprise inspections.
d) Reviewing staff sign-out records manually.
Clear selection
Which is the most critical safety precaution when administering IV potassium chloride?
10 points
a) Diluting it in normal saline.
b) Using a rapid bolus injection.
c) Administering it in an unmonitored setting.
d) Storing it alongside non-electrolyte medications.
Clear selection
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