Unit 17: Genetic Inheritance (final)
“This final Knowledge Audit will gauge your understanding of the material for the "Genetic Inheritance" unit after instruction has ended. Your teacher will use the information to see where you have grown and what you still feel you need to improve on. Please answer each question accurately and honestly."
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Syllabus Statements
For each statement below, indicate your level of confidence and knowledge about the statement using the following scale:
1. Very poor: you've never heard of this topic or idea.
2. Poor: you've heard this, but couldn't tell share any detailed information about it.
3. Fair: you remember the basic information about this topic or idea.
4. Good: you remember details and examples about this topic or idea.
5. Very good: you could teach others about this topic or idea.
3.4.U1: Mendel discovered the principles of inheritance with experiments in which large numbers of pea plants were crossed *
Describe Mendel’s pea plant experiments.
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Very Good
3.4.NOS: Making quantitative measurements with replicates to ensure reliability, Mendel’s genetic crosses with peas plants generated numerical data *
Outline why Mendel’s success is attributed to his use of pea plants. List three biological research methods pioneered by Mendel.
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3.4.U2: Gametes are haploid so contain only one allele of each gene *
Define gamete and zygote. State two similarities and two differences between male and female gametes
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3.4.U4: Fusion of gametes results in diploid zygotes with two alleles of each gene that may be the same allele or different alleles *
Outline the possible combination of alleles in a diploid zygote for a gene with two alleles. Outline the possible combination of alleles in a diploid zygote for a gene with three alleles.
Very Poor
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3.4.S1: Construction of Punnett grids for predicting the outcomes of monohybrid genetic crosses *
Define monohybrid, true breeding, P and F1. Determine possible alleles present in gametes given parent genotypes. Construct Punnett grids for single gene crosses to predict the offspring genotype and phenotype ratios.
Very Poor
Very Good
3.4.U5: Dominant alleles mask the effect of recessive alleles but codominant alleles have joint effects *
Define dominant allele and recessive allele. State an example of a dominant and recessive allele found in pea plants. State the usual cause of one allele being dominant over another. Define codominant alleles. Using the correct notation, outline an example of codominant alleles.
Very Poor
Very Good
3.4.U9: Many genetic diseases have been identified in humans but most are very rare *
List five example genetic diseases. Explain why most genetic diseases are rare in a population.
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3.4.U6: Many genetic diseases in human are due to recessive alleles of autosomal genes *
Define “carrier” as related to genetic diseases. Explain why genetic diseases usually appear unexpectedly in a population.
Very Poor
Very Good
D.1.A2: Cause and treatment of phenylketonuria *
Outline the genetic cause of phenylketonuria. List consequences of phenylketonuria if untreated.
Very Poor
Very Good
3.4.U7: Some genetic diseases are sex-linked and some are due to dominant or codominant alleles *
Describe why it is not possible to be a carrier of a disease caused by a dominant allele. Outline inheritance patterns of genetic diseases caused by dominant alleles. Explain sickle cell anemia as an example of a genetic disease caused by codominant alleles. Define sex linkage.
Very Poor
Very Good
3.4.A3: Inheritance of cystic fibrosis and Huntington’s disease *
Describe the relationship between the genetic cause of cystic fibrosis and the symptoms of the disease. Outline the inheritance pattern of cystic fibrosis. Outline the inheritance pattern of Huntington’s disease. List effects of Huntington’s disease on an affected individual.
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Very Good
3.4.A1: Inheritance of ABO blood groups *
Describe ABO blood groups as an example of complete dominance and codominance. Outline the differences in glycoproteins present in people with different blood types.
Very Poor
Very Good
3.4.U8: The pattern of inheritance is different with sex-linked genes due to to their location on sex chromosomes *
Outline Thomas Morgan’s elucidation of sex linked genes with Drosophila. Use correct notation for sex linked genes. Describe the pattern of inheritance for sex linked genes. Construct Punnet grids for sex linked crosses to predict the offspring genotype and phenotype ratios.
Very Poor
Very Good
3.4.A2: Red-green color blindness and hemophilia as examples of sex-linked inheritance *
Describe the cause and effect of red-green color blindness. Explain inheritance patterns of red-green color blindness. Describe the cause and effect of hemophilia. Explain inheritance patterns of hemophilia.
Very Poor
Very Good
3.4.S3: Analysis of pedigree charts to deduce the pattern of inheritance of genetic diseases *
Outline the conventions for constructing pedigree charts. Deduce inheritance patterns given a pedigree chart.
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Very Good
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