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* Indicates required question
Email
*
Your email
First Name
*
Your answer
Last Name
*
Your answer
Company or Institution
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Your answer
Does your company or lab have an area of focus in DNA damage and/or genomic instability?
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Yes, we study mechanisms related to DNA damage and/or genomic instability
Not really, but we are heading in that direction
No, our work is not related to DNA damage or genomic instability
If you are a drug-developing company, how many drug candidates do you currently have in different phases of your drug developmental pipeline - including discovery, pre-clinical, clinical, and post-approval stages.Â
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0
1
2
3
4
5
5+
Discovery
Pre-clinical
Clinical - Phase 1
Clinical - Phase 2
Clinical - Phase 3
Post-approval
Entering discovery phase in the incoming quarter
0
1
2
3
4
5
5+
Discovery
Pre-clinical
Clinical - Phase 1
Clinical - Phase 2
Clinical - Phase 3
Post-approval
Entering discovery phase in the incoming quarter
How many do you anticipate will enter your pipeline in the next quarter?
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0
1
2
3
4
5
5+
Discovery
Pre-clinical
Clinical - Phase 1
Clinical - Phase 2
Clinical - Phase 3
Post-approval
Entering discovery phase in the incoming quarter
0
1
2
3
4
5
5+
Discovery
Pre-clinical
Clinical - Phase 1
Clinical - Phase 2
Clinical - Phase 3
Post-approval
Entering discovery phase in the incoming quarter
Does your company or lab frequently perform Gentoxicity assays (such as the Ames test, the Mouse Micronucleus test, or the Chromosomal Aberration test)?
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Yes
No
Required
If you answered "Yes" in the previous question, would a deeper probe into the genome-wide mapping of sequences that undergo DNA double-stranded breakage from treatment of cells with your drug candidates or compounds provide additional valuable information? Please explain or provide details.Â
Your answer
BreakSight’s services map and identify genomic sequences that undergo frequent DNA double-strand breakage in cells exposed to treatment(s) that
induces acute DNA damage. Would this technology add value to your company or research to advance drug characterization and gain unique mechanistic insights, or is it similar to existing assays or screens that your company or lab employs? If so, which assay(s) or screen(s)?
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Your answer
What does your bioinformatics team search for in NGS data? What applications do your company or lab utilize this data for?
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Your answer
What more would you like to see done to characterize your drug(s) or compounds? (i.e. more in vitro or in vivo studies, greater basic or mechanistic research, expanded biomarker identification, etc.)
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Your answer
Are there any analytical tools you use that characterize or probe into the role of simple or complex DNA repeats in your research? If not, would such tools be of interest?
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ExpansionHunter
RepeatMasker
Tandem Repeats Finder
Other:
Required
Are there any particular genomic elements or patterns that you are interested inÂ
your research?
*
Your answer
Other comments or questions:
Your answer
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