YPIC Challenge II registration
The first edition of our YPIC challenge was a big success and the winning team was announced at HUPO 2017: Axl Rose (Alexander Hogrebe and Rosa R. Jersie-Christensen) with their manuscript: "Sweet Google O’ Mine - The Importance of Online Search Engines for MS-facilitated, Database-independent Identification of Peptide-encoded Book Prefaces" (Jesper V. Olsen’s group at the Novo Nordisk Foundation Center for Protein Research). Make sure to go and check out some of the submitted manuscripts at http://eupa.org/ypic/the-challenge. They are all amazing!

You say what now?! Well, the YPIC challenge is a scientific game compiling team work, project management skills and requiring some clever experimental insights. Your team decides on how you go about, when you nail it and how to report your final findings! But there is one unifying concept: only proteomics scientists can crack the code, no matter how hard someone else would try...

Before you register below, make sure you are a YPIC member by filling out this form: https://tinyurl.com/YPICRegistration
It is free of charge and it gives access to a survey where you can tell us what we need to do: https://tinyurl.com/YPICsurvey2

But above all, go and have a look on Facebook to feel the Buzz: https://www.facebook.com/EuYPIC

And what is that challenge exactly? It is actually quite easy! First, you team up with a maximum of 2 other, complementary colleagues (mass spectrometrists, bioinformaticians, wet lab scientist,...). When registered with your team of 3 below, we will send you a protein, which you can analyze as you see fit (no restrictions here). This protein was expressed in E. coli by PolyQuant, a company that usually expresses QConCAT proteins (www.polyquant.com). This time however, it is something they never tried before: the sentence actually encodes an English sentence! Indeed, it turns out that English grammar and biology match surprisingly well :).

Because proteomics field is broad and versatile this time we offer several Challenge categories:

1. Answer E.coli.‘s question.
2. Three-dimensional Grammar (find out how this sentence folds)
3. Bioinformazing (develop the coolest bioinformatics approach to decipher the sentence)
4. Protein Punctuation (Look for the biological equivalent of punctuation: PTMs left behind by E. coli)
5. #Bioreactivity (can you generate and describe bioreactivity in this Twitter-sized message?)

Make sure to pick the one category that suits your expertise best.
As for any scientific challenge, we want you to present your methodologies and results in a short manuscript, according to the rules of publication (details will be shipped with the product sheet). And the more manuscripts we receive, the bigger our chance become of making this into a special issue of an peer-reviewed journal and thus a fully valid extra line on your CV!

At the end of the ride, you will have gone through a scientific challenge just like in every day life. This way, we can use your experiences to not only debrief on the outcome of the game but equally use it as a stepping stone for a discussion/workshop on real life in science at EuPA 2018, in June in Santiago De Compostella, Spain (http://www.eupa2018.com). Then, at the EuBIC Winter School 2019 (https://www.proteomics-academy.org/eubic-winter-school-2019), we will announce the category winners at our special Award Ceremony. Just to be clear: you do not have to be present at the Winter School because we will broadcast the ceremony live.

All category winners will be invited to present their YPIC Challenge results at EUPA Congress 2019 in Potsdam https://www.eupa2019.org/. The final winner of the YPIC Challenge #2 (best manuscript and presentation) will be announced during the YPIC Challenge award ceremony in Potsdam. They will go home with a timeless cup and a free registration to any of the future EuPA supported congresses or workshops.

You want to take part in this great adventure!? Well, you just have to fill in this registration form before November 25th and we will send you the protein sentence shortly! You have until December 15th 2018 to submit the manuscript.

If you have any question, do not hesitate to contact us via e-mail: ypic16@gmail.com or send us a facebook message: www.facebook.com/EuYPIC

The Young Proteomics Investigators Club

PS: PLEASE SEND US A CONFIRMATION E_MAIL WHEN THE SENTENCE HAS ARRIVED!

Important dates
Deadline for registration: November 25th 2018.

The challenge ends at December 15th 2018

Category winners anounced at the EuBIC Winter School 2019

YPIC Challenge #2 winner awarded at the EUPA Congress 2019

Team name *
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Last name, first name of all the teammates (max 3 persons per group) *
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Addressee first and last name (for peptide shipment) *
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Institute and Department *
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Street address + number (and box/floor) *
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Team coordinator e-mail address *
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