Chapter 12: The Cell Cycle Practice MCQ's (Campbell's Biology, 9e)
Multiple Choice

Identify the letter of the choice that best completes the statement or answers the question.
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Campbell's Biology, 9e - Chapter 12: The Cell Cycle Practice MCQ's
The centromere is a region in which: *
2 points
Starting with a fertilized egg (zygote), a series of five cell divisions would produce an early embryo with how many cells? *
2 points
If there are 20 chromatids in a cell, how many centromeres are there? *
2 points
For a newly evolving protist, what would be the advantage of using eukaryote-like cell division rather than binary fission? *
2 points
Suppose a biologist can separate one of a dozen pieces of chromatin from a eukaryotic (animal)nucleus. It might consist of which of the following? *
2 points
At which phase are centrioles beginning to move apart in animal cells? *
2 points
If cells in the process of dividing are subjected to colchicine, a drug that interferes with the formation of the spindle apparatus, at which stage will mitosis be arrested? *
2 points
If there are 20 centromeres in a cell at anaphase, how many chromosomes are there in each daughter cell following cytokinesis? *
2 points
Where do the microtubules of the spindle originate during mitosis in both plant and animal cells? *
2 points
Taxol is an anticancer drug extracted from the Pacific yew tree. In animal cells, Taxol disrupts microtubule formation by binding to microtubules and accelerating their assembly from the protein precursor, tubulin. Surprisingly, this stops mitosis. Specifically, Taxol must affect *
2 points
Which of the following are primarily responsible for cytokinesis in plant cells but not in animal cells? *
2 points
In which group of eukaryotic organisms does the nuclear envelope remain intact during mitosis? *
2 points
Movement of the chromosomes during anaphase would be most affected by a drug that: *
2 points
Measurements of the amount of DNA per nucleus were taken on a large number of cells from a growing fungus. The measured DNA levels ranged from 3 to 6 picograms per nucleus. In which stage of the cell cycle did the nucleus contain 6 picograms of DNA? *
2 points
A group of cells is assayed for DNA content immediately following mitosis and is found to have an average of 8 picograms of DNA per nucleus. How many picograms would be found at the end of S and the end of G2? *
2 points
For anaphase to begin, which of the following must occur? *
2 points
Why do chromosomes coil during mitosis? *
2 points
Which of the following best describes how chromosomes move toward the poles of the spindle during mitosis? *
2 points
Which of the following is a function of those spindle microtubules that do not attach to kinetochores? *
2 points
During which phase of mitosis do the chromatids become chromosomes? *
2 points
Which of the following was a discovery that had to be made before human chromosomes could be correctly counted? *
2 points
Which of the following is (are) required for motor proteins to function in the movement of chromosomes toward the poles of the mitotic spindle? *
2 points
What is a cleavage furrow? *
2 points
Which of the following proteins are involved in binary fission as well as eukaryotic mitotic division? *
2 points
Using which of the following techniques would enable your lab group to distinguish between a cell in G2 and a cell from the same organism in G1? *
2 points
You have the technology necessary to measure each of the following in a sample of animal cells: chlorophylls, organelle density, picograms of DNA, cell wall components, and enzymatic activity. Which would you expect to increase significantly from M to G1? *
2 points
A plant-derived protein known as colchicine can be used to poison cells by blocking the formation of the spindle. Which of the following would result if colchicine is added to a sample of cells in G2? *
2 points
What causes the decrease in the amount of cyclin at a specific point in the cell cycle? *
2 points
Which of the following is released by platelets in the vicinity of an injury? *
2 points
Which of the following is a protein synthesized at specific times during the cell cycle that associates with a kinase to form a catalytically active complex? *
2 points
Which of the following is a protein maintained at constant levels throughout the cell cycle that requires cyclin to become catalytically active? *
2 points
The cyclin component of MPF is destroyed toward the end of which phase? *
2 points
Proteins that are involved in the regulation of the cell cycle, and that show fluctuations in concentration during the cell cycle, are called: *
2 points
The MPF protein complex turns itself off by: *
2 points
A mutation results in a cell that no longer produces a normal protein kinase for the M phase checkpoint. Which of the following would likely be the immediate result of this mutation? *
2 points
Density-dependent inhibition is explained by which of the following? *
2 points
Which of the following is true concerning cancer cells? *
2 points
Which of the following describe(s) cyclin-dependent kinase (Cdk)? *
2 points
A particular cyclin called cyclin E forms a complex with Cdk2 (cyclin-dependent kinase 2). This complex is important for the progression of the cell from G1 into the S phase of the cell cycle. Which of the following statements is correct? *
2 points
Cells from an advanced malignant tumor most often have very abnormal chromosomes, and often an abnormal total number of chromosomes. Why might this occur? *
2 points
Besides the ability of some cancer cells to overproliferate, what else could logically result in a tumor? *
2 points
After which checkpoint is the cell first committed to continue the cell cycle through M? *
2 points
Why do neurons and some other specialized cells divide infrequently? *
2 points
Which of the following most accurately describes a cyclin? *
2 points
All cell cycle checkpoints are similar in which way? *
2 points
At the M phase checkpoint, the complex allows for what to occur? *
2 points
What explains anchorage dependence of animal cells in vitro or in vivo? *
2 points
A research team began a study of a cultured cell line. Their preliminary observations showed them that the cell line did not exhibit either density-dependent inhibition or anchorage dependence. What could they conclude right away? *
2 points
For a chemotherapeutic drug to be useful for treating cancer cells, which of the following is most desirable? *
2 points
You have a series of cells, all of which were derived from tumors, and you first need to find out which ones are malignant. What could you do? *
2 points
Use the following information to answer the questions below. The lettered circle in Figure 12.1 shows a diploid nucleus with four chromosomes. There are two pairs of homologous chromosomes, one long and the other short. One haploid set is symbolized as black and the other haploid set is gray. The chromosomes in the unlettered circle have not yet replicated. Choose the correct chromosomal conditions for the following stages.
What is the correct chromosomal condition at the prometaphase of mitosis? *
2 points
What is the correct chromosomal condition for one daughter nucleus at telophase of mitosis? *
2 points
If the cell whose nuclear material is shown in Figure 12.2 continues toward completion of mitosis, which of the following events would occur next? *
2 points
Captionless Image
In the figure above, mitosis is represented by which numbered part(s) of the cycle? *
2 points
G1 is represented by which numbered part(s) of the cycle? *
2 points
Which number represents DNA synthesis? *
2 points
Which number represents the point in the cell cycle during which the chromosomes are replicated? *
2 points
At which of the numbered regions would you expect to find cells at metaphase? *
2 points
MPF reaches its threshold concentration at the end of this stage. *
2 points
Use the data in Table 12.1 to answer the following questions. The data were obtained from a study of the length of time spent in each phase of the cell cycle by cells of three eukaryotic organisms designated beta, delta, and gamma.
Of the following, the best conclusion concerning the difference between the S phases for beta and gamma is that: *
2 points
The best conclusion concerning delta is that the cells: *
2 points
Scenario Questions: The following information applies to the questions below.Several organisms, primarily protists, have what are called intermediate mitotic organization.
These protists are intermediate in what sense? *
2 points
What is the most probable hypothesis about these intermediate forms of cell division? *
2 points
Use the following information to answer the questions below. Nucleotides can be radiolabeled before they are incorporated into newly forming DNA and can therefore be assayed to track their incorporation. In a set of experiments, a student—faculty research team used labeled T nucleotides and introduced these into the culture of dividing human cells at specific times.
Which of the following questions might be answered by such a method? *
2 points
The research team used the setup to study the incorporation of labeled nucleotides into a culture of lymphocytes and found that the lymphocytes incorporated the labeled nucleotide at a significantly higher level after a pathogen was introduced into the culture. They concluded that: *
2 points
Once they had determined which cells were dividing, the team wanted to use a non-radioactive method to track whether various physiological factors (such as food or body temperature) affect the action of the pathogen. Which of the following would be effective, simple, and safe? *
2 points
Use the following information to answer the questions below. The research team established similar lymphocyte cultures from a number of human donors, including healthy teenagers of both genders, patients already suffering from long-term bacterial infections, and elderly volunteers. They found that the increase in lymphocyte incorporation after pathogen introduction was slightly lower in some of the female teenagers and significantly lower in each of the elderly persons. They repeated the study with a larger number of samples but got the same results.
What might be among the research team's conclusions? *
2 points
Which of the following investigations might be most productive to show what the data on the teenagers might indicate? *
2 points
Use the following information to answer the questions below. A student is looking through his light microscope (~450 X) at a squashed and stained onion root tip. Some, but not all, of the cells have clearly visible chromosome strands.
When a cell is in anaphase of mitosis, which of the following will he see? *
2 points
When the cell has just completed telophase, which of the following does he see? *
2 points
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