Denosumab Usage Profile Study
Denosumab (common trade names Prolia and Xgeva) is a human monoclonal antibody for the treatment of osteoporosis, treatment-induced bone loss, bone metastases, and giant cell tumor of bone.Denosumab is a RANKL inhibitor, which works by preventing the development of osteoclasts.The use of Denosumab has seen extensive application in definitive and adjunctive roles in the musculoskeletal oncology arena. There have however been no good trials on recommended duration of therapy and dosage in the given situations posed for treatment. It is timely that the APMSTS provides a position statement and I thank you for your valuable contribution to this survey. This should not take more than 5 minutes of your valuable time. It is an independent undertaking by the APMSTS and is not aligned with any commercial entity.
Saminathan Suresh Nathan
Asia Pacific Musculoskeletal Tumor Society