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CO2 Transport in Blood – 20 MCQ Quiz
NEET-PG / Medical Physiology Quiz
Topic: Transport of CO2 from tissues to lungs
Total Questions: 20
Each question carries 1 mark.
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1. Approximately what percentage of CO2 is transported in blood as carbamino compounds, mainly carbaminohemoglobin?
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5%
10%
20%
70%
2. CO2 binds to which portion of hemoglobin to form carbaminohemoglobin?
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Heme iron
Globin portion
Porphyrin ring
2,3-BPG binding site
3. Deoxygenated hemoglobin can carry more CO2 than oxygenated hemoglobin. This phenomenon is called:
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Bohr effect
Haldane effect
Hamburger phenomenon
Root effect
4. What happens to carbaminohemoglobin when hemoglobin becomes oxygenated in the lungs?
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It binds more CO2
It releases CO2
It converts CO2 into bicarbonate
It binds chloride ions
5. Approximately what percentage of CO2 is transported in blood mainly as bicarbonate (HCO3−)?
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10%
20%
50%
70%
6. The enzyme that rapidly catalyzes the reaction between CO2 and water is:
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Carbonic anhydrase
Arginase
Catalase
Carboxylase
7. Carbonic anhydrase catalyzes the formation of which intermediate from CO2 and water?
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Carbonic acid
Lactic acid
Pyruvic acid
Nitric acid
8. Carbonic acid in red blood cells dissociates primarily into:
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Na+ and Cl−
H+ and HCO3−
H+ and CO3−
OH− and CO2
9. The H+ generated during CO2 transport in red blood cells is mainly buffered by:
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Plasma albumin only
Hemoglobin
Sodium chloride
Bicarbonate only
10. During bicarbonate formation in systemic capillaries, HCO3− leaves the RBC while which ion enters the RBC?
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Na+
K+
Cl−
Ca2+
11. The exchange of bicarbonate leaving the RBC for chloride entering the RBC is called:
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Bohr effect
Haldane effect
Chloride shift
Root effect
12. Another name for the chloride shift is:
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Hamburger phenomenon
Haldane phenomenon
Bohr phenomenon
Donnan effect
13. Where does the chloride shift occur prominently during systemic CO2 transport?
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In systemic tissues
Only in the kidneys
Only in the alveoli
Only in the pulmonary artery
14. In the lungs, oxygenation of hemoglobin facilitates the release of:
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More CO2
More O2
More chloride into plasma only
More glucose
15. In the pulmonary capillaries, bicarbonate re-enters the RBC and is converted ultimately into:
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O2
CO2
Nitrogen
Ammonia
16. Approximately what percentage of total CO2 is transported simply dissolved in plasma?
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2%
10%
30%
70%
17. Which combination represents the three major forms of CO2 transport in blood?
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Dissolved CO2, carbamino compounds, bicarbonate
Oxyhemoglobin, dissolved O2, bicarbonate
Carboxyhemoglobin, bicarbonate, chloride
Carbonic acid, oxygen, nitrogen
18. The ability of deoxygenated hemoglobin to bind CO2 and H+ more effectively helps explain which effect?
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Haldane effect
Bohr effect only
Frank-Starling effect
Fick principle
19. In respiratory failure with CO2 retention, the primary abnormality is:
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Hypocapnia
Hypercapnia
Hyperoxia
Metabolic alkalosis only
20. Which respiratory pattern may occur in severe respiratory failure with progressive CO2 retention and hypoxia?
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Only normal eupnea
Cheyne-Stokes breathing and eventually respiratory arrest
Only voluntary apnea
Only sighing respiration
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