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Aggressive Versus Palliative Treatment in Pet Cancer and Histology and immunophenotyping on lymphnode and spleen samples
AC/2069/19
SMS code: a21039
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1. Which one of the tumours listed below is most amenable to excisional biopsy?
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1 point
slow growing mass
rapidly growing mass
ulcerated mass
mass on the distal limb
Client willing to go for curative therapy
2. Which one of the following is the MOST CORRECT definition of the term palliative treatment in veterinary oncology?
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1 point
Supportive symptomatic care for the terminal patient
The use of chemotherapy, surgery and radiation therapy with curative intent
Pain control in the pet with cancer
Lower dose chemotherapy or radiation to extend and improve quality of life
The use of alternative medications as a treatment option for the pet with cancer
3. Which one of the factors listed below is not a true risk factor for the development of lymphoma in dogs?
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1 point
Breed susceptibility
Environmental toxins and pollutants
Dysfunctional immune system
Frequent vaccination
Electromagnetic fields
4. Which one of the following statements regarding canine lymphoma is INCORRECT?
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1 point
Multicentric lymphoma occurs in about 75% of dogs
Middle-aged to older and medium-sized to larger dog breeds are more affected
Canine lymphoma mimics non-hodgkins lymphoma in humans
Sub-staging has little to no prognostic significance
WHO classifies canine lymphoma in five stages
5. The most recent literature classifies 5 most common lymphoma histiotypes. Which one of the 5 listed below is INCORRECT?
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1 point
Indolent marginal zone B cell lymphoma
Peripheral T cell lymphoma
Lymphoblastic T cell lymphoma
FeLV-induced T cell lymphoma
Diffuse large B cell lymphoma
6. Which one of the methods listed below is most helpful in getting the best out of your lymph node biopsy?
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1 point
The sample must be allowed to stand for at least 30 minutes before placing into formalin
The mandibular lymph nodes are most reactive so are the best ones to biopsy in generalised lymphadenomegaly
Tru cut needle biopsies are advantageous as they provide multiple areas of tissue to evaluate
Excise at least a third, but preferably remove the whole lymph node for histopathology
The lymph node sample must be cut in with a scissors to allow proper penetration of the formalin
7. Which one of the following statements regarding newer diagnostic methods for canine and feline lymphoma is CORRECT?
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1 point
PARR is used when histopathology cannot reliably differentiate between lymphoid hyperplasia and lymphoma
Flow cytometry analyses different cell populations based solely on phenotype and differences in cell size and granularity
Immunocytology retains superior cell morphology and is therefore more reliable than immunohistochemistry
Immunohistochemistry will usually differentiate between a clonal and non-clonal population of lymphocytes.
Cytology and immunocytochemistry is sufficient to diagnose the most common histiotypes
8. Which one of the following statements regarding histological subtyping of lymphoma is INCORRECT?
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1 point
Histological subtyping affects prognosis
Histological subtyping facilitates selection of the best treatment protocols
Histological subtyping allows for targeted research into specific tumour types
Histological subtyping can be made using an incisional biopsy of a lymph node
Histological subtyping cannot be made using cytology alone
9. Which one of the following statements regarding feline lymphoma is INCORRECT?
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1 point
T-cell lymphomas predominate in cats
Alimentary lymphoma is a common anatomic form in cats
Peripheral and/or visceral lymph node involvement is common in cats
Young cats < 2years old with generalised lymph node involvement often have lymphoid hyperplasia secondary to FeLV
Mediastinal lymphoma in FeLV negative Siamese cats can often be totally cured
10. Which one of the statements regarding the different histiotypes of lymphoma is INCORRECT?
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1 point
Feline epitheliotropic small cell intestinal lymphoma is low grade and responds well to chemotherapy
Feline large cell transmural lymphoma is high grade and respond poorly to chemotherapy
Endoscopic biopsies are sufficient to differentiate IBD from intestinal lymphoma in cats
High grade nodal diffuse large B cell lymphomas are aggressive, requiring CHOP therapy
Nodal marginal zone lymphomas in dogs respond well to prednisolone and chlorambucil
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