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Maximising Histopathology in Oncology Patients
AC/1986/18
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1. In oncology which of the following cannot be achieved with a surgical biopsy?
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1 point
Confirming a diagnosis.
Assessing the progress of therapy.
Grading of the tumor.
Determining the completeness of excision.
Determining the cause of death.
2. Which of the following features is considered the upside of surgical pathology?
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1 point
The pathologist does not see the gross lesion.
They is usually minimal or no autolysis.
There is time for reflection on the pathology
Minimal history is required.
Clinical data is not needed.
3. What does not constitute a diagnostic biopsy?
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1 point
An adequate amount of tissue.
Is representative of the neoplastic process.
Artifacts are not an issue.
Signalment, history and description of the lesion.
Differential diagnoses for the lesion.
4. What is the advantage of Tru-cut biopsies?
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1 point
They permit some evaluation of architecture and all minimally invasive.
Significant conclusions can be drawn from histopathology in 100% of cases.
Surgical margins can be deceased.
Metastatic spread can be evaluated.
Mitotic index can be considered reliable.
5. What is the disadvantage of endoscopic/laparoscopic biopsies?
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1 point
It is an invasive procedure.
Tissues cannot be observed for sampling.
Corrective surgery cannot be performed at the same time.
General anesthesia is required.
Open laparotomy, thoracotomy or cystectomy is required.
6. Which of the following are critical to obtaining a biopsy representative of the neoplastic process?
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1 point
Collecting biopsies from the center of the lesion.
Necrotic areas provide highly diagnostic information.
Always use techniques which allow for direct visualization of the lesion being sampled.
Areas with hemorrhage and/all inflammation provide diagnostic information.
Conflict biopsies from the age of the lesion.
7. What is the ideal thickness of tissue slices to ensure that adequate formalin fixation?
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1 point
0.5 – 1 cm.
1.5 – 2 cm.
2.5 – 3 cm.
3.5 – 4 cm.
4.5 – 5 cm.
8. Which of the following biopsies would be the most susceptible to crush artifacts?
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1 point
Incisional biopsies of solid masses.
Punch biopsies of skin masses.
Incisional biopsies of skin masses.
Tru cut biopsies.
Excision will biopsies.
9. Which of the following is not essential in the clinicians gross description of the tumour?
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1 point
Size.
Color.
Location
Distribution.
Smell.
10. Which of the following actions by clinicians is most likely to result in misdiagnosis?
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1 point
Describe what you see at gross examination.
Explain what treatment you employed.
Tell the pathologist nothing to avoid bias.
Provide the pathologist with your clinical differential diagnoses.
Tell the pathologist what you want him/her to look for.
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