The FIP Jigsaw-Puzzle

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AC/1504/16

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1. Which one of the following statements about FIP is INCORRECT? *

1 point

FIP is caused by the intestinal corona virus FCoV.

FIP is caused by a virulent mutation of the corona virus.

FIP is caused by an aberrant response of the host to the mutated corona virus.

FIP is caused by the mutated virus FIPV.

FIP virus is present in 90% of the feline population.

2. Which one of the following statements regarding the prevalence of FIP is INCORRECT? *

1 point

The prevalence of enteric corona virus can reach 90% in breeding catteries.

Less than 5% of cats infected with FCoV will go on to develop FIP.

50 - 70% of FIP occurs in cats older than one year of age.

Pure breed cats appear more susceptible.

High density population in rescue kennels is a risk.

3. Which one of the following statements regarding effusions in FIP is INCORRECT? *

1 point

Less than half of the effusions occurring in cats are due to FIP

Ascites and pleural effusion characterise the wet form of FIP

The effusion due to FIP has a characteristic appearance

Tests performed on the effusion may be more diagnostic than those performed on blood.

Effusions in a young cat are almost diagnostic for FIP

4. Which one of the following clinical signs is NOT typical of the dry form of FIP? *

1 point

Intraocular changes such as uveitis

Refractory pyrexia

Dyspnoea

Enlarged abdominal lymphnodes

Neurological signs

5. Which of the following statements regarding FIP effusions is INCORRECT? *

1 point

The cell count of the effusion is generally low (<2x109/L).

The fluid is generally clear and straw coloured.

The fluid had a high protein content making it quite viscous.

The major contribution to the protein content is albumin from vascular leakage

The Rivalta test is a simple test to show high protein content of fluid.

6. Which of the patterns of effusion characteristics listed below is MOST UNLIKELY to be FIP *

1 point

An effusion with a high cell count, a predominance of macrophages, low protein concentration , AG ratio >0.8 and negative Rivalta test

An effusion with a low cell count, predominance of cells other than neutrophils and macrophages , a low protein concentration and a A/G ratio of >0.8 and a positive Rivalta test

An effusion with a low cell count, a predominance of cells other than neutrophils and macrophages, a high protein concentration , and A/G ratio of >0.8 and a positive Rivalta test

An effusion with a low cell count, a predominance of cells other than neutrophils and macrophages, a high protein concentration , and A/G ratio of >0.6 and a positive Rivalta test

An effusion with a high cell count , predominance of cells other than neutrophils and macrophages, low protein concentration (<30 g/L), A/G ratio >0.8 and negative Rivalta test is

7. Which one of the following statements regarding immunohistochemical staining for FIP is INCORRECT? *

1 point

Immunohistochemical staining demonstrates presence of virus in the plasma

Immunohistochemical staining demonstrates presence of virus in the macrophages in the effusion

Immunohistochemical staining demonstrates presence of virus in the macrophages in tiisue biopsies

Immunohistochemnistry is 100% predictive and specific for FIP

Immunohistochemistry is not 100% sensitive - false negatives can occur

8. Which of the following statements regarding FeCoV titres is INCORRECT? *

1 point

You can get false negative titres in the terminal phase of the disease

Serum corona titres are a good screen test for FIP infection

Serum corona titres test for feline corona virus not FIPV

Serum titres are only significant if titres are very high (1: 1600) with a classical clinical presentation

Titres can be tested in blood and effusion fluid.

9. Which one of the following statements is INCORRECT? *

1 point

False negatives occur frequently with PCR in blood

Routine PCR can distinguish between FCoV and FIPV

Serum electrophoresis generally shows a polyclonal or even a monoclonal gammopathy , but is not specific for FIP

Acute phase proteins are elevated in cats with FIP – but are also once again , non specific.

AGP( alpha1 –acid-glycoprotein is elevated in cats with FIP versus cats with other causes of systemic inflammation

10. A problem with FIP in a cattery can be managed by doing which one of the following? *

1 point

Tested the blood of all the cats for FCoV titres

Doing PCR of blood of all the cats

Doing PCR of the faeces of all the cats to detect shedders

Euthanasing cats who are positive shedders

Doing electrophoresis to check for acute phase proteins in all the cats

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