Living with FeLV-infected Cats: a Guide for Veterinarians and their Clients

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AC/1992/18

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1. Which one of the statements listed does NOT apply to the regressive (latent) infection of FeLV? *

1 point

occurs when a cat clears the infection

causes a cat to become temporarily viraemic

becomes ill from FeLV-associated diseases

it does have viral DNA integrated into its genome

shed virus in their saliva, ocular and nasal secretions, urine, faeces and milk and are thus infectious to other cats

2. Which one of the statements listed does NOT apply to the progressive stage (persistently viraemic) stage of FELV? *

1 point

Progressively infected cats can survive months to years

Progressively infected cats shed virus in their saliva, ocular and nasal secretions, urine, faeces and milk

and are thus infectious to other cats.

Approximately two-thirds of cats exposed to FeLV will experience the progressive stage of infection

and may die of FeLV-associated diseases

3. Which one of the disease listed below is NOT typical of cats infected with FeLV? *

1 point

lymphoma

leukaemia

anaemia

infectious diseases

Neutropenia

4. Which one of the statements below is CORRECT concerning confirmatory testing for FeLV? *

1 point

a bone marrow sample is required for a confirmatory test for integrated viral DNA

Recommended confirmatory tests are either indirect fluorescent antibody (IFA) tests that pro-virus in infected leukocytes or platelets

Screening tests are usually ELISA-based tests and most cats will test positive within 2 weeks of exposure

Confirmatory polymerase chain reaction (PCR)-based tests detect p27 FeLV antigen

Confirmatory IFA tests don’t usually yield positive results until 45 – 60 days after initial infection when secondary viremia has occurred after infection of bone marrow.

5. Which one statement below is INCORRECT? *

1 point

Any new cats or kittens should be screened for FeLV infection before being introduced into a household

Household cats that go outdoors or share a house with cats that go outdoors should be FeLV-tested at least yearly

any cat that becomes clinically ill should be tested for FeLV immediately if it shares a household with an FeLV-infected cat

Healthy cats which tests positive on the ELISA test should be euthanased

Household cats that may have been exposed to other cats with unknown FeLV infection status should be immediately tested for FeLV and retested six weeks after exposure

6. Which criteria listed below is NOT an indicator to vaccinate an individual cat against FeLV? *

1 point

Kittens, because younger animals are more susceptible

Strictly indoor cats

Cats that have contact with cats with access to outdoors

Cats that live with FeLV-infected cats

Cats that may encounter other cats with unknown FeLV status

7. Which one of the statements below regarding treatment of FeLV ill cats is INCORRECT? *

1 point

Early therapeutic intervention is key to a successful treatment outcome in FeLV-infected cats that display clinical signs

First, the clinician should determine whether the illness is directly associated with FeLV infection or secondary due to immune dysfunction

Intensive diagnostic testing should occur earlier during a diagnostic workup as opposed to a “wait-and-see” approach

Most FeLV-infected cats respond well to appropriate medications and treatment strategies, but they may require a longer or more aggressive course of treatment and need to be more closely monitored during recovery.

Antiviral drugs and immunomodulators are the cornerstone to managing cats with FeLV

8. Separation of FeLV-infected cats from uninfected cats is ideal . If an owner is not prepared to separate cats which one of the factors listed below is UNTRUE? *

1 point

If an owner is unwilling to separate the FeLV-infected cat from non-infected cats then the non-infected cats should be adequately FeLV-vaccinated

Vaccination of non-infected cats does guarantee 100% protection, even in high-exposure environments

No new cats should be added to the household because this would disrupt the social structure and possibly increase the risk of cat fights and bites

However, providing separate feeding stations for infected and non-infected cats may help decrease the degree of exposure

FeLV is also labile outside of the host, remains infectious for only minutes in the environment and FeLV is readily inactivated with soap and disinfectants

9. Which one of the following statements is most correct? *

1 point

A positive ELISA in a cat without clinical signs consistent with FeLV is less reliable in sick cats

A positive result in a healthy cat should always be confirmed

As the prevalence of FeLV decreases so does the percentage of false positive ELISA test results

Cats with an antigen confirmed positive test cannot overcome the viraemia

Six weeks is the cut-off time for a cat to develop a regressive infection - ie for those with transient viraemia to overcome infection

10. Which one of the following statements is correct regarding a multi-cat household? *

1 point

30- 40% of the cats will develop persistent viraemia (progressive infection)

30 – 40% of the cats will show transient viraemia (regressive infection)

20 – 30% of the cats will show antibodies without being viraemic (abortive infection)

Regressively affected cats are not at risk for developing clinical disease

All of the above

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