Whole Genome Sequencing of the World's Oldest People
Supercentenarians (110 years or older) are the world’s oldest people. Seventy four are alive worldwide, with twenty two in the United States. We performed whole-genome sequencing on 17 supercentenarians to explore the genetic basis underlying extreme human longevity. The DNA sequence of all 17 supercentenarian genomes is available as a resource to assist the discovery of the genetic basis of extreme longevity in future studies. This study was a collaboration between Stanford University (Dr. Stuart K. Kim), the Institute of Systems Biology (Dr. Leroy Hood), and the Supercentenarian Research Foundation (Dr. L. Stephen Coles).
After we have reviewed your information, you will be emailed the details (in ~1 week) for how to access the Complete Genomics files from the bucket gs://sc_genomes/mastervar using gsutil.
DATA USE AGREEMENT
I request access to supercentenarian genome sequence data for the purpose of scientific research, and agree to the following terms:
1. I will receive access to de-identified data and will not attempt to establish the identity of, or attempt to contact any supercentenarian subjects or their families.
2. I will not attempt to make direct contact with study investigators or other staff concerning the specific results of individual subjects.
3. I will not further disclose these data beyond the uses outlined in this agreement, and understand that redistribution of data in any manner is prohibited.
4. I will require anyone on my team who utilizes these data, or anyone with whom I share these data to comply with this data use agreement.
5. I will accurately provide the requested information for persons who will use these data.
6. If I publish abstracts or papers using these genome data, I will cite the source of data (Gierman et al. 2014, Whole Genome Sequencing of the World's Oldest People, PLoS ONE).