1. Medial Patella Luxation 2. Are all Generics Created Equal?

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1. Medial Patella Luxation 2. Are all Generics Created Equal?

AC/1694/17

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SAVC Registration Number *

1. Which one of the following statements regarding bioequivalence is CORRECT? *

1 point

Bioequivalence means the medications has the same active ingredient

Bioequivalence is the comparison between the plasma profile of the test product and reference product

Bioequivalence means the medications have the same pharmacodynamics

Bioequivalence is the maintained for a medication between species

Bioequivalence mechanisms are independent of pharmocokinetics

2. Which statement below is the most CORRECT definition of pharmacokinetics? *

1 point

Pharmacokinetics is the study of the drug in vivo

Pharmacokinetics is the study of the movement of drug through the body

Pharmacokinetics is the study of the effect of the drug within the body

Phamacokintetics is evaluated by measuring the peak level of the drug in the plasma

Pharmacockinetics evaluates the chemical change occurring in the drug within the plasma

3. Which one of the factors below does NOT affect absorption of a drug? *

1 point

The site of administration

The amount administered

The drugs chemical profile

The ability of the body to remove the drug

The rate of drug administration

4. Which one of the statements below is CORRECT? *

1 point

If two drugs achieve the same concentration in the plasma, they are not necessarily equally as effective.

The formulation controls the time to a drug’s first effect, the degree of effect but does not affect the degree of side effects

The chemical forms of the active ingredient are all equally effective

Efficacy can be presumed if a formulation has the same active as another product

In pharmacokinetics the key controlling aspect is the drug formulation which controls absorption and elimination.

5. Which of the one of the factors listed below is INCORRECT with regard to generic medications? *

1 point

A generic drug is a formulation that contains the same active ingredient as the innovator

A generic drug is registered through an abbreviated process known as bioequivalence

Generic compounds are generally simple formulations and don’t need to comply with GMP requirements

For bioequivalence, each profile has to be compared for each route for which the drug is registeredv

For bioequivalence each profile has to be compared to each species for which the drug is registered.

6. Which one of the following statements regarding patella luxation is CORRECT? *

1 point

Medial patella luxation (MPL) is a common traumatic orthopaedic condition of the canine patient.

Small breed dogs are more commonly affected by MPL than large breed dogs.

Lateral patella luxation is more common than medial patella luxation in large breed dogs

MPL can also be seen in cats, the surgical management is more complex than in dogs.

Tibial deformity consistently underlies the development of MPL in dogs

7. Which one of the following statements regarding the diagnosis of MPL is CORRECT? *

1 point

Radiographs are generally not required to diagnose MPL - it is a clinical diagnosis

MPLis a significant cause of middle age onset of lameness in small breed dogs

Concurrent conditions such as cranial cruciate rupture may often cause the clinical lameness in small breed dogs with MPL

These patients may also have distal femoral valgus and hypoplasia of the lateral femoral condyle

The grading system for MPL is helpful to plan a surgical strategy

8. Which one of the statements regarding the surgical repair of patella luxation listed below is most CORRECT? *

1 point

Surgical repair of patella luxation should be performed on any small breed patient showing greater than a grade 2 luxation.

Surgery should be performed in young animals to prevent the long-term complications later on in life from the patella luxation.

It has been shown that soft tissue procedures performed without correction of the bone deformities is an acceptable approach as a sole method.

Complications using the TCT in combination with soft tissue repair techniques are low

Surgical repair most often utilizes one or the other of either soft tissue repair or bone repair to reposition the patella

9. Which of the following statements regarding the RidgeStop™ are INCORRECT? *

1 point

It is a high-density polyurethane implant placed on the medial trochlear ridge requiring 3 bone screws to accurately secure the implant

It should only be used alone in cases of mild patella luxations with no marked bone deformity of the leg.

It can be used together with the bone corrective techniques to augment repair.

The RidgeStop™ method is combined with the trochlearplasty to give best repositioning of the patella

It adds significantly to the cost of the surgical procedure

10. A tibial crest transplant has been the standard operation used for re-alignment of the bony structures. Which of the statements below is INCORRECT? *

1 point

This technique is simple to perform but can have catastrophic complications.

The complication rate varies from 9-50% for a tibial crest transplant.

Of the cases which develop recurrent patella luxation, all will show clinical signs of lameness

Complications seen are tibial crest fracture , tibial crest infection and tibial fracture

Implant migration will not affect outcome after clinical union has occurred.

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