Miscellaneous Notes 6

by

Jur Plesman

Web

 Alcoholism may run in families, Alzheimer’s Disease & Brain shrinkage, Combination AD Medications,  Antidepressant drugs & heart disease,  Anti-inflammatory Drugs & AD Medications, Anti-Vaccination movement, B-Vitamins and brain shrinkage, Brain works,  Breast Cancer, Iron, Aluminium, Alcohol & elder abuse, Auckland District Health &Vit C Cancer,  Bipolar under-diagnosed, Birds & Viatmin D,  Breast Cancer & Omega-3 Fatty acids,  CAM use among the elderly, Codeine morbidity,  CT Radiation & cancer,   Combined AD Medications, Cognitive Decline, Complementary Medicine in Switzerland, Dark chocolate, Creatine & glucose tolerance, Dementia & Sarcasm,  Depressed mothers, Depression boosts pain,  Diabetes & Parkinson’s Disease, Diabetes & Vit D,  Diabetes rising in US, Diabetic Drugs & CV risks, Doctors to be trained, Drug Addiction & Crime, Drug use,  Ecstasy, Ecstacy & Brain Damage, Factory farming and bacteria,  Fatty Liver & Vitamin E, Gambling Treatement, Genetics can be beaten, Ginger for Pain relief, Ginkgo Biloba & Migraine, Hemp oil & cancer,  Herbal remedies by Mediherb, High Blood Pressure and Kidney Cancer,  Lead poisoning & amulet, Leucine in Whey Protein, Light at night & obesity, Low Vitamin D & Parkinson’s Disease, Macular Degeneration & Vit D,  Metabolic Syndrome & Mental Illness, Metformin & heart Disease, Mold exposure in the home,  Mood disorders & Osteoporosis, Multivitamins & Cancer, Prostate, Omega-3 & Schizophrenia, Prostate Cancer & Supplements, Prostatectomy & Cancer,  PTSD soldiers, PUFAs & ADHD,  Romantic Rejection, Sage extract & memory,  Salt intake & CVD, Smoking & Cancer, Smoking & Children, Statins & Peripheral Neuropathy,  Stress & Immune system, Stress & disablity, Sunscreen Products,  Sunshine & Monocleosis,  Trans-fatty acids & CVD mortality, Trans-palmitoleic acid, Turmeric & Osteoarthritis,  Sugar & Obesity, Urinary Incontinence & caffeine,  Vitamin D & Colorectal Cancer, Vitamin D & Asthma, Vitamin D & lung infections, Vitamin D & Teen Obesity, Vitamin D & Parkinson’s Disease,


Breast Cancer and Iron and aluminium. A compelling number of studies, though not all, have shown that free iron concentrations in breast tissue, especially the ductal tissue, is playing a major role in stimulating cancer development and eventual progression to aggressive, deadly cancers.1,2 A number of studies have found that extracting nipple fluid by a breast pump (in both premenopausal and postmenopausal women) is a simple way to study the microenvironment of the ductal tissue, the site of development of most breast cancers.5 Examining this ductal fluid is an excellent way to measure such things as iron levels, ferritin (an iron-binding protein), CRP (a measure of breast inflammation) and aluminum. Russle L. Blaylock MD, CCN at Dr Mercola

Breast Cancer and Omega-3 fatty acids. Our results provide experimental support to the hypothesis that omega-3 PUFAs can be used as modulators of tumor cell chemosensitivity and provide the rationale for in vivo preclinical investigation. In addition, this is the first study demonstrating that omega-3 PUFA DHA downregulates Her-2/neu oncogene expression in human breast cancer cells. PMID: 15901996

Vitamin D & Colorectal Cancer. Vitamin D can be derived from the diet but in most populations it is mainly produced endogenously from sun exposure.1 The primary role of vitamin D is the maintenance of calcium homoeostasis and bone metabolism. Vitamin D might also play an important part in cancer control by modulating cellular growth and apoptosis and by reducing angiogenesis.2 The results of this large observational study indicate a strong inverse association between levels of pre-diagnostic 25-(OH)D concentration and risk of colorectal cancer in western European populations. Further randomised trials are needed to assess whether increases in circulating 25-(OH)D concentration can effectively decrease the risk of colorectal cancer. BMJ 2010; 340o; b5500

Doctors must be trained in Nutritional Medicine. Nutrition is a core element in the first year of a junior doctor course, but it is not a mandatory part of medical school curriculums or many specialist training courses in the latter part of the junior doctor training programme.

Dr Neild said as a gastroenterologist she had to deal with the consequences of severe malnutrition which requires tube-feeding to be introduced.

"The problem is that doctors do not recognise it and if it is not picked up the patients cannot be passed on to dieticians to address the problem.

"Doctors are taught a lot about medical interventions, but not how to assess and manage poor nutrition." BBC News 18 march2010

Comments: Patients interested in receiving holistic medical treatment have an option to choose a medical or health practitioner with post graduate qualifications in nutritional medicine obtained from such institutions as ACNEM or International Academy of Clinical Nutrition or AANMC

Depressed mother and their children*

FRIDAY, March 25 (HealthDay News) -- Even very young children can get stressed by depressed parents who display negative emotions toward them, researchers confirm.

The new study included 3-year-old children who were subjected to different harmless, but stress-inducing, situations, such as causing them to become slightly nervous or frustrated. After each stressful event, saliva samples were taken from the children to measure levels of the stress hormone cortisol. The largest stress responses were seen in children whose mothers had been depressed at some point in the child's life and whose mothers also displayed hostility -- frustration, anger, annoyance or critical comments -- when playing with their children. Medline Plus 25/3/11

Stress affects gut bacteria  and immunity

FRIDAY, March 25, 2011 (HealthDay News) -- Researchers have found that stress can alter the balance of bacteria that live in the intestine, leading to immune system problems. MedlinePlus

Stress and disability

THURSDAY, March 24 (HealthDay News) -- Even mild stress can cause long-term disability that prevents people from working, new research suggests.

While it has long been known that mental disorders can be a cause of disability, the new findings indicate that the effects of milder forms of stress should be taken more seriously, according to Dheeraj Rai, of the University of Bristol in the United Kingdom, and colleagues. MedlinePlus 24/3/2011

Bipolar Disorder no always diagnosed. Nearly 40 percent of people with major depression may also have subthreshold hypomania, a form of mania that does not fully meet current diagnostic criteria for bipolar disorder (go to page 7), according to a new NIMH-funded study. The study was published online ahead of print August 15, 2010, in the American Journal of Psychiatry. NIMH August 2010  

Depression boosts arthritis pain

"The results of this study indicate that depression can play a major role in the way patients experience the symptoms of knee arthritis, and that even when X-rays show the arthritis is not severe, patients with depression may report significant pain," said Dr. Tae Kyun Kim. MedlinePlus March 22, 2011

Sugar and body weight

THURSDAY, March 24 (HealthDay News) -- As Americans' intake of sugars added to processed and home-cooked foods rises, so, too, does body weight, according to a study that followed Minnesota residents for 27 years. MedlinePlus 24 March 2011

Dark Chocolate and diabetes, blood pressure. THURSDAY, March 24, 2011 (HealthDay News) -- If you can handle the fat and calories, there may be a health benefit to enjoying dark chocolate on occasion. New research suggests that the cocoa ingredient may lower blood pressure and cholesterol levels while preventing diabetes and improving the health of blood vessels. MedlinePlus

Romantic Rejection

MONDAY, March 28, 2011 (HealthDay News) -- Memories of devastating heartbreaks appear to trigger activity in the brain that's similar to when people suffer physical pain, new research suggests.

"This tells us how serious rejection can be sometimes," said study author Edward E. Smith, director of cognitive neuroscience at Columbia University. "When people are saying 'I really feel in pain about this breakup,' you don't want to trivialize it and dismiss it by saying 'It's all in your mind.'"

The finding could lead to more than a better understanding of the link between emotional and physical pain, Smith said. "Our ultimate goal is to see what kind of therapeutic approach might be useful in relieving the pain of rejection." MedlinePlus  Also read: Romantic Rejection: Trigger fro Depression

Alcohol and elder abuse: The analysis revealed that 29 percent of abuse victims tested positive for alcohol, compared to 13 percent of the control group. "Past studies have shown that alcohol abuse by the perpetrator plays a substantial role and is strongly associated with physical abuse," lead study author Lee Friedman, assistant professor of environmental and occupational health sciences at the University of Illinois at Chicago, said in a university news release. "Our findings indicate that alcohol abuse among the victims may be an important contributing factor as well." MedlinePLus March25,2011

Multivitamins does not protect against cancer

Wednesday, March 23, 2011

By Leigh Krietsch Boerner

NEW YORK (Reuters Health) - Will taking multivitamins protect you from dying of cancer or heart disease? The answer is no, according to new research.

In a study of more than 180,000 people, scientists saw the same number of deaths from cancer and heart disease among multivitamin-takers and those who did not take the supplements.

"People need to understand that just taking these multivitamins is not sufficient to prevent disease," said Jennifer Hsiang-Ling Lin, assistant professor of medicine at Brigham and Women's Hospital in Boston, who did not work on the study.

Multiple past studies have shown no link between multivitamins and reduced risk of cancer or heart disease. Other recent research couldn't prove that multivitamins protect against diabetes, either. MedlinePlus  But see contradictory information at Cancer & Nutrition

Ecstacy, The dangers

Tuesday, March 29, 2011

By Kerry Grens

NEW YORK (Reuters Health) - For a glimpse into real-world drug use, Australian researchers went to parties where people were using a drug known as ecstasy - and discovered that users' brains were at far more risk from the drug than anyone had suspected.

The researchers also found that ecstasy pills often contain a variety of other drugs.

"What's concerning is that most studies looking at toxicity in people or animals look at a single drug," said Dr. Thomas Newton, a professor at Baylor College of Medicine, who was not involved in this study.

"We have no idea what happens when you start mixing like this." MedlinePLus

Drug addiction & crime: Addiction is recognized as a chronic, relapsing disease, offenders are still not getting the treatment they need. In recent decades, the number of adults involved in the criminal justice system has soared from about 1.8 million in 1980 to 7.3 million in 2007, due largely to prosecutions of drug-related crimes and drug-addicted offenders. Criminal offenders have rates of substance abuse and dependence that are more than four times that of the general population. As in the general population, co-occurring substance use and other mental disorders are common, with about 45% of inmates in local jails and State prisons having both. In addition, about 75% of inmates with a mental illness also meet criteria for substance abuse, and vice-versa. This high rate of co-occurrence underscores the need for offenders, both adults and juveniles, suffering from one disorder to be screened for the other and, where appropriate, treated for both, necessitating an integrated treatment approach. US Department of Health & Human Services

Diabetes and Parkinson's disease

NEW YORK (Reuters Health) - People with diabetes may have a slightly increased risk of developing Parkinson's disease, a new study suggests -- though the reasons for the link, researchers say, are far from clear.

The study, of nearly 289,000 older U.S. adults, found that those with diabetes at the outset were more likely to be diagnosed with Parkinson's over the next 15 years.

Of 21,600 participants with diabetes, 172 (0.8 percent) were eventually diagnosed with Parkinson's. That compared with 1,393 cases (0.5 percent) among the 267,000 men and women who were diabetes-free at the study's start. MedlinePlus March 30, 2011

Comments: If 0.8 Percents of a total population of diabetics were eventually diagnosed with Parkinson's Disease, compared to 0.5 percent of non-diabetic population, then the ultimate probability of people with or without diabetes of falling victim to Parkinson's Disease is only 0.5 - 0.8 percent, hardly sufficient to implicate diabetes as an important factor.

Smoking and Throat & Stomach Cancer

NEW YORK (Reuters Health) - Smokers face an increased risk of certain types of throat and stomach cancers, even years after they quit, a new study finds.

Combining the results of 33 past studies, Italian researchers found that current smokers were more than twice as likely as nonsmokers to develop cancer, either in their esophagus or in a part of the stomach called the gastric cardia. March,29, 2011

Prostate: Benign Prostatic Hyperplasia

Testosterone is metabolized in your body to dihydrotestosterone by the enzyme 5 alpha reductase.

Excess DHT is thought to be the major factor in Benign Prostatic Hyperplasia (BPH). But this is denied here, where it is argued that DHT (not testosterone) is responsible for prostate enlargement.

The fatty acids (lauric acid, oleic acid, myristic acid and palmitic acid) in Saw Palmetto, Serenoa repens, are thought to prevent testosterone from converting into dihydrotestosterone (DHT), which causes prostate cells to multiply.

Supplements for a healthy prostate:

Also see: Studies that show that excess testosterone is not the culprit in the enlargement of the prostate gland here.

Drug use increases among teenagers: The study, sponsored by MetLife Foundation and the 22nd in an annual series, found that between 2008 and 2010 teens who said they had used marijuana in the past year climbed to 39 percent from 32 percent.

Between 2008 and 2010, teens who said they had used the "party" drug ecstasy in the past year increased to 10 percent from six percent. MelinPlus 6 April 2011

See also  MedlinePlus 8 Sept 2011 reporting that 22.6 million Americans or 8.9 percent are using illegal drugs.

How birds obtain their vitamin D

Your pet bird has an uropygial (rump of bird) or “preen” gland above the base of the tail. This gland secretes oil. As your bird grooms, it spreads this

oil over its feathers. This oil contains a compound that produces vitamin D when exposed to the sun’s ultraviolet rays. So as your bird grooms under an

ultraviolet light source, it’s actually mixing up a healthy batch of vitamin D on its feathers. As your bird re-grooms his feathers coated in oil, he ingests the vitamin D. The vitamin D in his system will then be converted by his kidneys and liver to active vitamin D3 (cholecalciferol). MedKB 27 Jan 2010

VITAMIN D DEFICIENCY & PARKINSON'S DISEASE

Researchers report that there is a correlation between insufficient levels of vitamin D and the development of early Parkinson's disease.

A study of more than 150 Parkinson's patients found that a high percentage of subjects had vitamin D insufficiency or deficiency. Almost 70 percent had vitamin D insufficiency (defined as levels of less than 30 nanograms per milliliter) at the beginning of the study, while about 26 percent were classified as deficient (levels of less than 20 nanograms per milliliter.)

The prevalence of insufficiency at the final visit was over 51 percent, and deficiency occurred in 7 percent.

Life Extension Magazine reports:

"Previous studies ... [suggested] that long-term effects of Parkinson's disease may contribute to the development of insufficient vitamin D concentrations ... Contrary to [the] expectation that vitamin D levels might decrease over time because of disease-related inactivity and reduced sun exposure, vitamin D levels increased over the study period.

These findings are consistent with the possibility that long-term insufficiency is present before the clinical manifestations of Parkinson's disease and may play a role in the pathogenesis of PD." Mercola April 2011 Archives of neurology 2011;68(3):314-319

Secondhand smoke and children 

The study adds to evidence suggesting that kids of mothers who smoked while pregnant may be more likely to have behavioral problems. Secondhand smoke exposure has also been linked to heart and breathing problems in kids. MedlinePlus 7 April 2011

Metabolic Syndrome and mental illness

Ecstacy users and brain damage

WEDNESDAY, April 6 (HealthDay News) -- Long-term users of the illegal drug ecstasy are at risk for brain damage, warns a new study.

Brain scans showed an approximate 10 percent shrinkage in the volume of the hippocampus and a lower proportion of overall gray matter among long-term ecstasy users, the researchers found. MedlinePlus

Omega-3 Supplements & Schizophrenia

Antipsychotic medication has been used as a method of prevention and has proved effective. However, utilizing antipsychotics remains controversial because between 70 and 80 percent who are considered high-risk do not develop a psychotic disorder within a year. Because antipsychotics have been shown to have a variety of adverse side effects, many believe they should not be administered unless necessary (i.e., after a psychotic disorder has been diagnosed). Consequently, researchers have searched for a method that would not expose individuals to the side-effects of antipsychotics if possible. In a recent study, researchers found that long-chain ?-3 (omega 3) polyunsaturated fatty acids (PUFAs) could be administering as a preventive measure to reduce the risk of a psychotic disorder from emerging. While 27.5 percent of individuals given a placebo experienced further development of their psychosis only 4.9 percent of participants who were given Omega-3 supplements saw their condition worsen. NamiAdvocate

Urinary incontinence & caffeine

NEW YORK (Reuters Health) - Despite international guidelines that suggest cutting caffeine to counter urinary incontinence, a new study finds that coffee or tea may not have much effect on the condition.

In a study of more than 14,000 Swedish twins, researchers found that drinking tea did not significantly increase the odds of having a leaky bladder. When age was taken into account, coffee drinkers had a somewhat decreased risk of the urinary disorder.

There have been plenty of studies about incontinence and caffeine, but the results have been inconsistent, according to lead author Giorgio Tettamanti, a doctoral student in epidemiology at the Karolinska Institutet in Stockholm, Sweden. MedlinePlus

Metformin and heart disease

THURSDAY, April 7 (HealthDay News) -- The commonly used oral diabetes drug metformin not only helps stabilize blood sugar levels, it also may offer protection against heart disease, researchers say.

In a study that included more than 100,000 residents of Denmark taking metformin or another group of oral diabetes medications called insulin secretagogues (ISs), researchers found that metformin and the IS drugs gliclazide and repaglinide had the lowest risk of cardiovascular disease and death. MedlinePLus

Fatty Liver Disease and Vitamin E

The concept of using antioxidants in children with nonalcoholic steatohepatitis (NASH) was stimulated by studies demonstrating that vitamin E (800 IU/day) was beneficial in adults with NASH.[2] Liver enzyme levels improved in 43% of patients in the vitamin E treatment group compared with 19% in the placebo-treated group. The rationale for the administration of agents with strong antioxidant activity to patients with NASH is a good one, given the presumed pathophysiology of disease progression in patients with fatty liver disease.[3,4] Medscape

Gambling treatment

Work by an Israeli researcher into gambling addiction suggests the most effective treatment for the disorder should include medication and psychotherapy — for at least two years.

Psychiatrist Dr. Pinhas Dannon of Tel Aviv University’s Sackler Faculty of Medicine said the extended treatment regimen would utilize Naltrexone, a drug used to treat alcoholism, and be complemented with other treatments, including group therapy. PsychCentral

Comments: It should be realized that most gamblers are hypoglycemic and should be treated for this as part of overall treatment.

Prevention of cognitive decline, dementia

The body can produce some phosphatidylserine (PS) but needs additional sources from

Cow Brain        713 mg/100g

Mackerel        480

Herring        360

Organ Meat         305

Chicken        134

Beans        107

Beef        85                

Whole Milk        1

Vegetarian diet tend to supply less than 50 mg of phosphatidylserine. About 30 years ago when the daily intake was about 260 mg.

Bioactive Choline  is another essential nutrients to prevent cognitive decline. It is rich in eggs (raw), beef liver, chicken liver, cottage cheese, whole milk, red cabbage, sweet potatoes, raspberries

Mercola  See also article By Dr Chris Reading Alzheimers disease

Genetics can be beaten by nutrition.

Research findings demonstrating how genetic expression can be modified with natural substances to prevent chronic illness was the topic of an address by Jeffrey Bland, Ph.D., FACN, FACB, at the 8th Annual Scripps Center for Integrative Medicine 2011 conference in San Diego, California, January 13 – 16. Chronic illness is a major threat to health care in America. Currently, 75 percent of the almost $2.5 trillion spent on health care in the U.S. each year is used to treat chronic diseases, many of which are related to lifestyle factors. An estimated one out of every three American adults suffer from metabolic syndrome, which more than doubles their risk for diabetes, heart attack, and stroke. Metagenics’ approach and its products are distinguished by the rigorous research behind them to document their scientific validity. For example, preliminary findings from clinical trials conducted by the University of Connecticut, University of Florida, and the University of California at Irvine demonstrated that the addition of a Metagenics’ medical food, UltraMeal ® PLUS 360° to a low-glycemic Mediterranean diet, outperformed diet alone in reducing risk factors for cardiovascular disease. Metagenics Jan 2011.

Complementary Medicine in Switzerland

In Switzerland, health insurance, which is backed by the state, will now cover five types of complementary medicine until 2017 after the government issued a new ruling. There will however be an independent investigation of whether or not they work.

In 2009 there was a referendum in the country and 67 per cent of the electorate balloted in favour for complementary medicine to be covered by health insurance . The five therapies to be offered are homeopathy, herbal and traditional Chinese treatments, anthroposophic medicine, which among other techniques uses mistletoe to treat cancer and neural therapy, which is based on injecting local anaesthetics near nerve centres.

However in December, according to a scientific panel, acting on behalf of the Swiss government, the methods used did not meet objective measures of efficiency. This is considered to be unlawful, as health insurance is required by law to pay only for such treatments. Ignazio Cassis, national vice-chairman of the Swiss Medical Association said the only legal solution was to pay for the five methods temporarily, but they all must prove their "efficacy, cost-effectiveness and suitability" by 2017.

Insurances.co.UK

Comments: It is strange that Nutritional Medicine is not considered!

Diabetes rising in US

An estimated 25.8 million Americans, or 8.3% of the population, have diabetes and almost a third of those don't know it, the CDC said.

Another 79 million people have prediabetes, with high fasting glucose or hemoglobin A1c levels but not quite at the frank diabetes level, the agency said in its National Diabetes Fact Sheet for 2011. Medpage Jan 2011

Trans-palmitoleic acid (in dairy fat) may reduce risk type 2 diabetes

Scientists at the Harvard School of Public Health (HSPH) and collaborators from other institutions have identified a natural substance in dairy fat that may substantially reduce the risk of type 2 diabetes. The compound, trans-palmitoleic acid, is a fatty acid found in milk, cheese, yogurt, and butter. It is not produced by the body and so only comes from the diet.Researchers explain that trans-palmitoleic acid may underlie evidence in recent years that diets rich in dairy foods are linked to lower risk of type 2 diabetes and related metabolic abnormalities. Health experts generally advise reducing full-fat dairy products, but trans-palmitoleic acid is found in dairy fat. AFN Thought for Food December 2010 and The Heart.org

"Trans-palmitoleic acid is a fatty acid relatively unique to dairy foods. We don't make it in our bodies, so consuming it is the only way for it to enter the bloodstream. This study provides evidence that people who have higher levels of blood trans-palmitoleic acid have a significantly lower risk of diabetes mellitus, as well as other metabolic risk markers." "Circulating palmitoleic acid, which is derived from endogenous fat synthesis, might regulate and protect against insulin resistance. In the present study, the researchers wanted to determine whether an exogenous source of palmitoleate would also have a beneficial effect on metabolic risk factors, and to do so they measured circulating levels of trans-palmitoleic acid, a fatty acid derived from dairy sources that has not been linked with increased cardiovascular risk." "Another study published in the American Journal of Clinical Nutrition tackled the dairy question, with investigators, led by Dr Sabita Soedamah-Muthu (Wageningen University, the Netherlands), performing a meta-analysis of 17 prospective studies evaluating the association between milk and dairy consumption and risk of cardiovascular disease, stroke, and total mortality [2].

Overall, investigators observed a modest inverse association between milk intake and the risk of overall cardiovascular disease, with milk consumption associated with a 6% lower risk of cardiovascular disease. Milk intake was not associated with the risk of coronary heart disease or total mortality.

"Milk and dairy products cannot be recommended to benefit cardiovascular disease health outcomes on the basis of this dose-response meta-analysis," conclude the authors. "[The] intake of milk and dairy products does not seem to be harmful, but whether the association is truly inverse cannot be firmly concluded."

Trials of dairy consumption, although limited in number, also failed to show an association with coronary heart disease." PreventionThe Heart.org December 2010

High levels of dietary trans-palmitoleic acid (a fatty acid naturally occurring in milk and other dairy products) were found strongly correlated with reduced risk of type 2 diabetes and reduced cardiovascular risk markers.[11] Overall milk consumption may have a beneficial effect.[12]

There are numerous studies which suggest connections between some aspects of type 2 diabetes with ingestion of certain foods or with some drugs. Breastfeeding may also be associated with the prevention of type 2 diabetes in mothers.[13] Wikipedia

Herbal Remedies for digestive system for a healthy gut by Mediherb

Herbs & Nutrients to Assist Healthy Gastrointestinal Function:

Components

Title

File

Phellodendron, Andrographis, Anise essential oil, Oregano essential oil

Essential Oils & Herbs: Treatment of Intestinal Dysbiosis

Click Here

Garlic

Major Oral Applications of Standardised Garlic Extract & Whole Garlic

Click Here

Slippery Elm

The Numerous Healing Properties of Slippery Elm

Click Here

Grape Seed extract, Green Tea, Turmeric, Rosemary

Antioxidant Herbs to Support Health & Vitality

Click Here

Golden Seal

Golden Seal: Quality Issues

Click Here

Lactobacillus acidophilus LA-5, Bifidobacterium animalis lactis BB-12

Probiotics for Good Health

Click Here

Clinical Articles

Title

Summary

File

Bowel Flora

A Bowel Flora Protocol for Dysbiosis Management

The bowel flora protocol explained in detail. Includes case study (chronic digestive issues).

Published: 2004

Click Here

Effect of apple intake on fecal microbiota and metabolites in humans

Summary of clinical study results: Consumption of apples supported healthy bowel flora in volunteers.

Published: 2011

Click Here

Whole-grain wheat breakfast cereal has a prebiotic effect on the human gut microbiota: a double-blind, placebo-controlled, crossover study

Summary of clinical study results: A prebiotic effect was observed in volunteers receiving whole grain wheat.

Published: 2008

Click Here

Conditions involving Bowel Flora

Case Report: Ulcerative Colitis

Case study: Kerry Bone outlines successful treatment of a particularly challenging case of ulcerative colitis, featuring the use of the bowel flora protocol.

Published: 2006

Click Here

Phytotherapy for Crohn’s Disease

Case study of Crohn’s disease – part of a discussion of autoimmune disorders. One of the first occasions of Kerry Bone’s writing of the bowel flora protocol, as proposed by Hein Zeylstra.

Published: 1995

Click Here

Rheumatoid Arthritis, Bowel Flora and Diet

Short discussion of the improvement in symptoms of rheumatoid arthritis observed by application of a vegan diet, possibly due to a favourable change in bowel flora profile.

Published: 1998

Click Here

Low Vitamin D may be the precursor to Parkinson's disease

People with a recent diagnosis of Parkinson’s disease (PD) were found to have low blood levels of vitamin D in a study published in the March 2011 issue of Neurology.  The study authors suggest that people with PD may not have been getting enough vitamin D for a long time before Parkinson’s symptoms developed, and that vitamin D deficiency may play a role in causing the disease. Parkinson's Disease Foundation April 2011

Vitamin D3 supplementation may stabilize PD for a short period in patients with FokI TT or CT genotypes without triggering hypercalcemia, although this effect may be nonspecific for PD. This trial was registered at UMIN Clinical Trials Registry as UMIN000001841. PMID:23485413

CAM Use and the elderly

Use of CAM is widespread. The 2007 National Health Interview Survey, a nationwide Government survey, found that 38 percent of U.S. adults reported using CAM in the previous 12 months, with the highest rates among people aged 50–59 (44 percent)1. The NHIS data also revealed that approximately 42 percent of adults who used CAM in the past 12 months disclosed their use of CAM to a physician (M.D.) or osteopathic physician (D.O.)2. Because many adults also use over-the-counter medications, prescription drugs, or other conventional medical approaches to manage their health, communication between patients and health care providers about CAM and conventional therapies is vital to ensuring safe, integrated use of all health care approaches. NCAM

Dementia and ability to recognise sarcasm or lies

FRIDAY, April 15 (HealthDay News) -- People who no longer recognize sarcasm or lies may be showing early signs of dementia, researchers from the University of California, San Francisco report. MedlinePlus     Comments: Elderly people with signs of dementia may fall victim to commercial scams.

Brain shrinks in Alzheimer's Disease

WEDNESDAY, April 13, 2011 (HealthDay News) -- The brains of people diagnosed with Alzheimer's disease start shrinking up to a decade before symptoms appear, a new study finds. MedlinePLus 

Diabetic Drugs and CV risk:

Copenhagen, Denmark - Most sulfonylureas used by a cohort of diabetic adults across Denmark raised clinical risk compared with metformin, regardless of MI history, according to an analysis published online April 6, 2011 in the European Heart Journal [1].

In general, the risk of death from any cause and a composite CV-event end point went up significantly in association with glimepiride, glibenclamide, glipizide, and tolbutamide use, compared with metformin, while gliclazide and repaglinide were on a par with metformin for those risks, among the >107 000 patients who started on the drugs as monotherapy between 1997 and 2006. www.theheart.org

Trans-fatty acids linked to higher CVD mortality. Geneva, Switzerland - Trans-fatty acids (TFAs) that occur naturally in ruminant fat and those from partially hydrogenated fish oils (PHFOs) both contribute to increased cardiovascular and coronary heart disease mortality, a new prospective study reported at the EuroPRevent 2011 meeting this past weekend shows [1]. www.the heart.org

Alcoholism may run in families SATURDAY, April 16 (HealthDay News) -- Children of parents with an alcohol use disorder (AUD) are at increased risk for the same type of problem, says a new study from Denmark.

The risk of an alcohol use disorder, which includes alcoholism and alcohol abuse, was higher among those whose parents had an AUD. The increased risk was independent of other major predictors, such as gender, parents' social status and the psychiatric hospitalization of parents, the researchers noted. MedlinePlus See also Diabetic Gene

Sunshine deficiency and infectious Monocleosis. MONDAY, April 18, 2011 (HealthDay News) -- Infection with Monocleosis -- the easily spread virus that's the bane of many college students -- and little exposure to sunlight may combine to boost a person's risk for developing multiple sclerosis, a new study suggests.

"MS is more common at higher latitudes, farther away from the equator," the study's lead researcher, Dr. George C. Ebers, of the University of Oxford in England, said in a statement provided by the American Academy of Neurology. "Since the disease has been linked to environmental factors such as low levels of sun exposure and a history of infectious mononucleosis, we wanted to see whether the two together would help explain the variance in the disease across the United Kingdom."  MedlinePlus

Sunscreen products may increase cancer. Researchers at the Environmental Working Group, a Washington-based nonprofit, released their annual report claiming nearly half of the 500 most popular sunscreen products may actually increase the speed at which malignant cells develop and spread skin cancer because they contain vitamin A and its derivatives, retinol and retinyl palmitate.

Furthermore, the FDA has known about the dangers of vitamin A in sunscreens since ordering a study 10 years ago, but has done nothing to alert the public of the dangers.

"Retinyl palmitate was selected by (FDA's) Center for Food Safety and Applied Nutrition for photo-toxicity and photocarcinogenicity testing based on the increasingly widespread use of this compound in cosmetic retail products for use on sun-exposed skin," said an October 2000 report by the National Toxicology Program. Dr Mercola

Lead poisoning due to Cambodian Amulet.

This report describes a case of lead poisoning in a child aged 1 year that was investigated by the New York City Department of Health and Mental Hygiene's (NYC DOHMH) Lead Poisoning Prevention Program in 2009. The likely source of exposure was an amulet made in Cambodia with leaded beads that was worn by the child. Health-care providers and public health workers should consider traditional customs when seeking sources of lead exposure in Southeast Asian populations. CDC 28 Jan 2011

Leucine in Whey Protein

Leucine is a branched chain amino acid found in certain foods.

It causes protein to be created and builds your muscle by its signaling of the mTOR (Mammalian Target of Rapamycin) mechanism.*

However, you need FAR more leucine than the Recommended Daily Allowance (RDA) to reap this muscle-building benefit.* In fact, you need massive amounts…

So where can you find leucine?

You'll find the highest concentrations of leucine and other branched chain amino acids (BCAA) in dairy products – especially quality cheeses and whey protein.

Even when getting leucine from your natural food supply, it's often wasted or used as a building block instead of an anabolic agent. So to create the correct anabolic environment, you need to boost leucine consumption way beyond mere maintenance levels.

Unfortunately, to get far and away your most competitive edge by exceeding maintenance levels is challenging. Here's why…

Based on nitrogen-balance measurements, the requirement for leucine that maintains your current body protein is 1-3 grams daily.

But to optimize its anabolic pathway, you need 8g - 16g daily.

This means that to reach 8 grams for anabolic purposes, you need the following humungous amounts of food:

But remarkably, you only need about 3oz of high-quality whey.

Clearly, supplementing with whey protein can effectively allow you to get that 8 g or more of leucine to build strong competitive muscle, without consuming freaky amounts of food and calories. For more information see   Mercola See also Branched Chain Amino Acids

Anti-inflammatory Meds can reduce effects of antidepressant drugs

Paul Greengard, Ph.D., and Jennifer Warner-Schmidt, Ph.D., discovered commonly used medications such as ibuprofen, aspirin and naproxen reduce the benefits of selective serotonin reuptake inhibitors (SSRIs) including fluoxetine (Prozac), sertraline (Zoloft), paroxetine (Paxil), fluvoxamine (Luvox) and citalopram (Celexa). According to the researchers, this discovery may explain why so many depressed patients taking SSRIs do not respond to treatment and that this lack of effectiveness may be preventable. PsychCentral 26.4.11

Macular Degeneration & vitamin D

Conclusions  High serum 25(OH)D concentrations may protect against early AMD in women younger than 75 years. Archives of Opthalmology Vol.129. No. 4, April 2011

Diabetes & Vitamin D

CONCLUSIONS Higher serum 25OHD levels, but not higher dietary calcium, were associated with a significantly reduced risk of diabetes in Australian adult men and women. PMID: 21430082

Antidepressant drugs increase risk of heart disease.

Taking antidepressants may raise the risk of heart disease in men by producing a thickening of artery walls, researchers said Saturday. Although a potential mechanism for the action is not obvious, the drugs appear to accelerate atherosclerosis by increasing the thickness of what is known as the intima media, the inner and middle layers of the arteries, particularly the carotid arteries that feed blood to the brain, researchers from Emory University in Atlanta reported at a New Orleans meeting of the American College of Cardiology.  ...the intima-media thickness of men taking antidepressants was 37 microns (about 5%) thicker than that of men not taking the drugs. When the team looked at 59 twin pairs in which one twin was taking the drugs and the second was not, the artery was 41 microns thicker in the twin taking the drugs. Los Angelos Time April 2, 2011

Women with  mood disorders have higher risk of osteoporosis

Women who suffer from major mood disorders and those who experience both psychosis and a substance use disorder (SUD) have a significantly increased risk for osteoporosis, research shows. PsychCentral 4/5/2011

Combination AD medication no better than one.

Depressed patients who take two medications fare no better than those who only taken one, according to researchers at the University of Texas Southwestern Medical Center.

“Clinicians should not rush to prescribe combinations of antidepressant medications as first-line treatment for patients with major depressive disorder,” said lead study investigator Dr. Madhukar H. Trivedi, professor of psychiatry and chief of the division of mood disorders at UT Southwestern. PsychCentral 3/5/2011

PTSD more likely among soldier with previous history of mental illness

Posttraumatic stress disorder (PTSD) is up to five times more likely to be developed by soldiers who had previous mental health issues, or had been previously injured during deployment, according to new research. PsychCentral 2/5/2011

Statins may be responsible for peripheral neuropathy

A 50-year-old man presented with clinical features of peripheral neuropathy with numbness in both feet. He had been prescribed statin therapy for a mixed hyperlipidaemia following a myocardial infarction at 40 years of age. Medscape 25/4/2011

CT Radiation and Cancer Risk

A Medscape Video 9 Minutes.

The Danger of Anti-vaccination Movement

Partinen, director of the Helsinki Sleep Clinic and Research Centre, had raised the alarm about a GlaxoSmithKline vaccine called Pandemrix. He had discovered the drug, used to protect people from H1N1 swine flu, may be linked to a jump in cases of narcolepsy, a rare sleep disorder, in children and young people. This sparked off a new debate about the use of vaccines.

Offitt, an American pediatrician quoting: "All those children's parents had chosen not to vaccinate them, and all of them said, 'I can't believe this happened to me,'" he told Reuters. "Vaccines are medical products. They have a benefit and - like any product that has a benefit - they could also have a risk. But from the public's standpoint it's difficult. For them, any risk is a bad thing."  Read the full story about the continuing vaccine debate at Medscape 21 March 2013

Medscape Video 21 minutes

The Auckland District Health Board Condemns High Dose Vitamin C Therapy

18-Sep-2010 10:46

But:

Auckland Health Board lies over Vitamin C

By Keith Stewart

Earlier this week the Chief Medical Officer of the Auckland District Health Board, Dr Margaret Wilsher issued a statement saying, "no evidence exists to confidently say that high-dosage Vitamin C therapy is either safe or effective."

She lied. High dose intravenous vitamin C branded as Astor L 500 was gazetted as a fully registered medicine by Medsafe in January this year. To satisfy Medsafe Astor L 500 is required by law to have a safety record that indicates no risk or harm to health. Put simply, Dr Wilsher, it is safe. If you have a problem with that, take it up with Medsafe. Dr Wilsher and the entire membership of the Auckland City Hospital Clinical Practice Committee, who advised her, should be prosecuted by the Ministry of Health for their failure to act in the best interests of the public they serve.

According to the Medical Council of New Zealand, "Good doctors are...honest and trustworthy and act with integrity."

Neither Dr Wilsher nor Dr David Geller, a member of her Clinical Practice Committee, have shown themselves to be either honest or trustworthy, and in the case of Dr Geller, has failed "...to keep [their] knowledge and skills up to date."

Source: RadioLive 18 Sept 2010

Dr. Monti Talks About Vitamin C Trials For Cancer Patients In Nbc 10 Video

An ongoing clinical trial being conducted at Jefferson is testing whether high doses of vitamin C given through an IV can stop cancer cells from growing in patients who have advanced pancreatic cancer or non-Hodgkin's lymphoma. Dr. Monti of the Jefferson-Myrna Brind Center of Integrative Medicine who is behind the study, talks about the treatment to NBC 10.

"Some people are doing exceedingly well. They're feeling better, they're feeling more energized, and their disease is doing better."

Learn more about the Integrative Cancer Care Program and open clinical trials at Jefferson.

Jefferson Univeristy Hospital 14 July 2010

See also: http://www.youtube.com/watch?v=QM94wa-VO_o

http://www.youtube.com/watch?v=EtjvbE9w58A&feature=related

http://www.youtube.com/watch?v=Y3x-Uj4yAMY&feature=related

B-Vitamins halve brain shrinkage in elderly

Daily tablets of large doses of B vitamins can halve the rate of brain shrinkage in elderly people with memory problems and may slow their progression toward dementia, data from a British trial showed on Wednesday, Reuters Sep 2010

But also see for negative results PMID: 20861451 and more positive results PMID: 20838622 Negative results for myocardial infarction: PMID: 20861174

Codeine phosphate drugs serious morbidity

Although codeine can be considered a relatively weak opioid analgesic, it is nevertheless addictive, and the significant morbidity and specific patient characteristics associated with overuse of codeine–ibuprofen analgesics support further awareness, investigation and monitoring of OTC codeine–ibuprofen analgesic use. MJA 2010; 193 (5): 294-296

Extracts of Salvia (sage) improves memory

Species of Salvia (sage) have a long-standing reputation in European medical herbalism, including for memory enhancement. In recent controlled trials, administration of sage extracts with established cholinergic properties improved cognitive function in young adults. Compared with the placebo condition (which exhibited the characteristic performance decline over the day), the 333-mg dose was associated with significant enhancement of secondary memory performance at all testing times. The same measure benefited to a lesser extent from other doses. There also were significant improvements to accuracy of attention following the 333-mg dose. In vitro analysis confirmed cholinesterase inhibiting properties for the extract. PMID: 18350281

Special Turmeric extracts benefits Osteoarthritis Patients

The characteristic yellow color of turmeric, which is found in many yellow mustards and yellow curry preparations, derives from compounds known collectively as curcuminoids, whose most abundant member is curcumin. Curcumin is difficult to absorb into the human bloodstream from the gastrointestinal tract when consumed orally. [4] Researchers in Italy selected 50 patients with X-ray diagnosed osteoarthritis in either one or both knees to evaluate if the special turmeric formulation called Meriva® could provide more benefits to their standard medical therapy. In this trial, the patients were split into two groups: the first one received standard medical treatment as determined by patients' physicians, while patients in the second group added the special curcumin extract to their standard medical treatment.

After 90 days, the following benefits were observed: Compared to the controls, patients in the Meriva group experienced a 58 percent decrease in their overall pain, stiffness and physical functionality as measured by the widely used medical scoring method developed by Western Ontario and McMaster Universities (WOMAC). Medical News Today 

Ginger for Pain Relief

Daily doses of raw or heat-treated ginger are effective for relieving muscle pain following strenuous exercise, according to research reported in The Journal of Pain, published by the American Pain Society. In one study, four to 36 weeks of daily ginger doses (30 to 500 mg.) achieved reductions in knee pain from osteoarthritis. Medical News Today, Sept 2010

Creatine improves glucose tolerance in Diabetes II

Creatine supplementation combined with an exercise program improves glycemic control in type 2 diabetic patients. The underlying mechanism seems to be related to an increase in GLUT-4 recruitment to the sarcolemma. PMID: 20881878 

Lower Vitamin D levels found among asthmatic children

Our results indicate that hypovitaminosis D is frequent in children with asthma living in a Mediterranean country. In those children, lower levels of vitamin D are associated with reduced asthma control. PMID: 20870246

A study linking light at night and obesity at PMID: 20937863

Supplementation of PUFA's benefit ADHD children

Our results suggest a beneficial effect of a combination of omega-3 and omega-6 fatty acids as well as magnesium and zinc consumption on attentional, behavioural, and emotional problems of children and adolescents. Thus, considering the behavioural benefit in combination with the low risk due to a good safety profile, the dietary supplementation with PUFA in combination with zinc and magnesium can be recommended. Lipids in health and Disease 2010, 9:109

Ginkgo Biloba Extract may help in MIgraine headaches among children.

In our sample after 3 months of treatment with association of Ginkgolide B/Coenzyme Q10/Riboflavin/Magnesium complex, the mean frequency per month of migraine was significantly decreased (9.71 ± 4.33 vs. 4.53 ± 3.96 attacks; p < 0.001). Our findings suggest that in childhood headache management, the use of alternative treatments must be considered not to evoke a placebo effect, but as soft therapy without adverse reactions. PMID: 20872034 

Hemp Oil a potential anti-cancer herb

"...perfectly balanced 1:3 ratio of naturally-occurring omega-3 and omega-6 essential fatty acids...unlike other seeds and nutritional oils, such as flax and fish fish oil, hemp seeds also contain super omega-3 stearidonic acid and super omega-6-gamma-linolenic acid in nutritionally relevant amounts that help to reduce inflammation and improve mental functioning, as well as make up for potentially impaired fatty acid metabolism." Mercola

Mold Exposure and health hazards in the home.

Mercola video, 1 hr 38 minutes

Factory farming an d bacteria in meat.

“For the study, researchers looked at 136 samples involving 80 brands of beef, chicken, pork and turkey from 26 grocery stores ... According to the findings ... industrial farms, where food animals are steadily fed low doses of antibiotics, ‘are ideal breeding grounds for drug-resistant bacteria that move from animals to humans.’”  Clinical Infectious Disease May 2011; 52(10):1227-30

Bronchiolitis in infants & Vitamin D Deficiency

Background:Respiratory syncytial virus (RSV) is the most important pathogen causing severe lower respiratory tract infection (LRTI) in infants. Epidemiologic and basic studies suggest that vitamin D may protect against RSV LRTI. Pediatrics, Los Anegelos Time May 9,2011

Obese Teens lack Vitamin D

WEDNESDAY, May 4, 2011 (HealthDay News) -- Low levels of vitamin D are common in obese adolescents, a new study finds.

Researchers screened 68 obese adolescents and found low vitamin D levels in all of the girls (72 percent were deemed deficient and 28 percent insufficient) and in 91 percent of the boys (69 percent deficient and 22 percent insufficient).

After treatment, 43 of the youths had their vitamin D levels measured again and, although levels generally increased, normal levels were achieved in just 28 percent of the participants. In the others, repeated bouts of vitamin D treatment did not bring the teens' vitamin D levels to normal, which the researchers described as "concerning."

The adolescents' lack of response to treatment may be due to the fact that vitamin D is sequestered in body fat, the researchers said. MedlinePLus

How the brain works

Here is a NIMH video as to how the brain works and how it can affect mental illness. This is a fairly old-fashioned explanation of mood disorders based on the outdated model of treatment with pharamceutical drugs and talk therapy, that by studies have been shown to have a fairly poor success rate. It completely ignores the fact that serotonin - the feel good neurotransmitter - is produced from nutrients in our food and that mood disorders may be simply a sign of a nutritional disorder.  NIMH Brain Basics

Salt intake not related to cardiovascular risks.

TUESDAY, May 3, 2011 (HealthDay News) -- The prevailing wisdom that high salt intake raises cardiovascular risks is being challenged by a new European study that suggests the opposite. The Polish and Belgian researchers acknowledge that all of the study volunteers were younger and white, and that may have skewed the results. Analyzing urine sodium tests from 3,681 participants with no previous cardiovascular disease, the scientists found that lower sodium excretion was associated with an increased risk of heart-related deaths and higher sodium excretion was not linked to increased risks for high blood pressure or complications from heart disease. MedlinePlus

Supplements don't prevent prostate cancer

by Kerry Grens

NEW YORK (Reuters Health) - A new study deflates hopes that certain nutritional supplements could stave off prostate cancer, the second most common cancer in men. Canadian researchers found that vitamin E, selenium and soy, taken daily for three years, provided no benefit to men who were at a higher risk of developing the disease. The findings come three years after a larger study of men, who were at no increased risk of prostate cancer, also found no benefit of selenium or vitamin E supplementation (see Reuters Health report, October 28, 2008). MedlinePLus May 4, 2011

High Blood Pressure may prevent Kidney Cancer.

The finding comes from a study of 544 people being treated with the drug sunitinib (Sutent) for advanced kidney cancer. The researchers found that those whose maximum systolic blood pressure reached 140 mmHg or higher survived nearly four times longer than those who had a lower maximum systolic blood pressure -- 30.5 months vs. 7.8 months. MedlinePlus

Combination AD Medications no improvements

A combination of two antidepressants may not be any more effective in treating chronic major depression than a single antidepressant, according to an NIMH-funded study published online ahead of print May 2, 2011, in the American Journal of Psychiatry. MedlienePlus 3 May 2011

Prostatectomy may prevent cancer

May 5, 2011 — Radical prostatectomy appears to be a wise choice for men with early-stage prostate cancer who are younger than 65 years, according to new data from a Swedish randomized clinical trial that compares surgery with "watchful waiting."

The study shows that, at 15 years, the cumulative incidence of death from prostate cancer was 14.6% among 347 men randomized to prostatectomy and 20.7% among 348 men being observed without treatment. Medscape May,5,2011