501 Massachusetts Avenue
Cambridge MA 02139
Research Associate
Job Description
The Company
Cellino is an innovation- and value-driven, venture capital-backed biotechnology company that is pioneering a transformative platform to manufacture cell-based therapies. The company was founded by a team of interdisciplinary, entrepreneurial scientists and engineers with expertise in laser physics, biology, software development, optics, precision instrumentation, and business.
The Role
Cellino is seeking a research associate with significant experience in human-induced pluripotent stem cell (hiPSC) and mammalian stem cell culture techniques. This position will report to the Senior Stem Cell Scientist and requires proficient technical experience in hiPSC reprogramming, expansion, and differentiation techniques. You will work very closely as part of our growing biology team and will actively participate in optimizing culture conditions and validation assays. Successful candidates should be scientifically motivated self-starters, comfortable working in a fast-paced entrepreneurial environment, excellent at rapid problem solving, and adept at communicating across disciplinary boundaries.
Responsibilities
● Independently maintain and provide hiPSC cultures for team use
● Optimize culture conditions as needed with Sr. Scientists (e.g. cell media, extracellular matrices, passaging methods for hiPSCs)
● Generate hiPSCs from multiple somatic cell types
● Optimize reprogramming protocols with Sr. Scientist(s)
● Differentiate hiPSCs to appropriate therapeutic cell types using appropriate differentiation techniques
● Use established SOPs to characterize hiPSCs and differentiated cells ● Clearly present and discuss results in team meetings
● Communicate well with other team members about all aspects of the project
Requirements
● BSc/MSc Degree in Biological sciences with 2+ years of experience in a biology lab ● Experience with mammalian cell culture and techniques including introduction of reagents into primary cells via viral vectors or electroporation and cationic lipid transfection
● Very strong technical experience in human iPSC culture
● Working knowledge of data analysis tools (e.g. Excel, GraphPad Prism) ● Ability to work well independently and as part of a cohesive team
● Ability to thrive in a fast-paced cross functional team environment
● Strong oral and written communication skills
● Strong collaborative software platform-based communication skills
● Must have work authorization for the United States
Nice-to-Have Skills and Background
● Experience in reprogramming somatic cells to hiPSCs
● Hands-on experience with basic molecular biology techniques such as Western blotting, qPCR, plasmid preparation, bacterial culture, flow cytometry, and cellular reporter assays
● Experience in isolation of DNA and RNA preferred
● Previous experience with CRISPR technologies
Benefits
● Competitive salaries
● Stock options
● 401(k)
● Employer-paid medical, dental, vision, and life insurance
● Flexible work schedule
● Generous paid time off and sick leave + 12 company holidays
● Parental leave
● Professional development assistance
It is the policy of Cellino Biotech, Inc. to provide equal employment opportunity for all applicants and employees. The Company does not unlawfully discriminate on the basis of race, religion, creed, color, national origin, ancestry, physical and/or mental disability, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, transgender status, pregnancy, marital status, age, sexual orientation, and military or veteran status, or any other basis protected by law. It also prohibits unlawful discrimination and harassment based on the perception that anyone has any of those characteristics or is associated with a person who has or is perceived as having any of those characteristics.