Unit 4: Proteins Biology - Goldenrod

6 classes

Date

Day

IB Topic

Activities

Objectives

Homework

10/31 & 11/1

19

2.4

  • Introduction to Proteins
  • Yogurt Lab
  • Protein Function Group Notes
  • Model Building Lab: Proteins

  • Living organisms synthesize many different proteins with a wide range of functions
  • Application: Denaturation of proteins by heat or by deviation of pH from the optimum.

11/7 & 11/8

20

2.4

  • Quiz: 2.4 Proteins
  • Protein Function Group Notes Sharing
  • Lactose Enzyme Lab
  • Data Analysis Practice 2

  • Amino acids are linked together by condensation to form polypeptides
  • There are 20 different amino acids in polypeptides synthesized on ribosomes
  • Amino acids can be linked together in any sequence giving a huge range of possible polypeptides
  • The amino acid sequence of polypeptides is coded for by genes
  • A protein may consist of a single polypeptide of more than one polypeptide linked together
  • The amino acid sequence determines the three dimensional conformation of a protein
  • Every individual has a unique proteome
  • Application: Rubisco, insulin, immunoglobulins, rhodopsin, collagen and spider silk as examples of the range of protein functions.
  • Skill: Drawing molecular diagrams to show the formation of a peptide bond.
  • 2.5 Enzyme Notes
  • Pg 152-157

11/9 & 11/13

21

2.5

  • Enzymes have an active site to which specific substrates bind
  • Enzyme catalysis involves molecular motion and the collision of substrates with the active site
  • Temperature, pH, and substrate concentration affect the rate of activity of enzymes
  • Enzymes can be denatured
  • Enzymes lower the activation energy of the chemical reactions that they catalyse.
  • Skill: Experimental investigation of a factor affecting enzyme activity (Practical 3)  
  • 8.1 Metabolism Notes
  • Pg. 158-160

11/14 & 11/15

22

2.5

  • Quiz: 8.1
  • Drawing peptide bonds
  • Competitive, non-competitive, end-product inhibition
  • Lab Standard Evaluation Explanation & Practice
  • Enzyme Lab
  • Analysis & Evaluation checklist handouts
  • Immobilized enzymes are widely used in industry
  • Application: Methods of production of lactose-free milk and its advantages.
  • Metabolic pathways consist of chains and cycles of enzyme-catalysed reactions.
  • Enzyme inhibitors can be competitive or non-competitive.
  • Metabolic pathways can be controlled by end-product inhibition.
  • Application: End-product inhibition of the pathway that converts threonine to isoleucine.
  • Skill: Design of experiments to test the effect of temperature, pH and substrate concentration of the activity of enzymes.
  • Data Analysis Practice 2 (Due beginning of class)

11/16 & 11/19

23

8.1

  • Review: End product inhibition
  • Grade Data Analysis 2
  • Anti-Material drugs databases
  • Distinguish types of inhibition from graphs
  • Analysis of enzyme graphs and data
  • Enzyme Lab write up
  • Hypotheses
  • Calculate reaction rates
  • Evaluation
  • Application: Use of databases to identify potential new anti-material drugs.
  • Skill: Calculating and plotting rates of reaction from raw experimental results.
  • Skill: Distinguishing different types of inhibition from graphs at specified substrate.

Study for Assessment

Molecular Biology Assessment Retakes Due 11/20

11/20 & 11/21

24

8.1

  • Review
  • Proteins Assessment
  • Complete Lab

Enzyme Lab