10/31 & 11/1
- Introduction to Proteins
- Yogurt Lab
- Protein Function Group Notes
- Model Building Lab: Proteins
- Living organisms synthesize many different proteins with a wide range of functions
- Application: Denaturation of proteins by heat or by deviation of pH from the optimum.
11/7 & 11/8
- Quiz: 2.4 Proteins
- Protein Function Group Notes Sharing
- Lactose Enzyme Lab
- Data Analysis Practice 2
- Amino acids are linked together by condensation to form polypeptides
- There are 20 different amino acids in polypeptides synthesized on ribosomes
- Amino acids can be linked together in any sequence giving a huge range of possible polypeptides
- The amino acid sequence of polypeptides is coded for by genes
- A protein may consist of a single polypeptide of more than one polypeptide linked together
- The amino acid sequence determines the three dimensional conformation of a protein
- Every individual has a unique proteome
- Application: Rubisco, insulin, immunoglobulins, rhodopsin, collagen and spider silk as examples of the range of protein functions.
- Skill: Drawing molecular diagrams to show the formation of a peptide bond.
- 2.5 Enzyme Notes
- Pg 152-157
11/9 & 11/13
- Enzymes have an active site to which specific substrates bind
- Enzyme catalysis involves molecular motion and the collision of substrates with the active site
- Temperature, pH, and substrate concentration affect the rate of activity of enzymes
- Enzymes can be denatured
- Enzymes lower the activation energy of the chemical reactions that they catalyse.
- Skill: Experimental investigation of a factor affecting enzyme activity (Practical 3)
- 8.1 Metabolism Notes
- Pg. 158-160
11/14 & 11/15
- Quiz: 8.1
- Drawing peptide bonds
- Competitive, non-competitive, end-product inhibition
- Lab Standard Evaluation Explanation & Practice
- Enzyme Lab
- Analysis & Evaluation checklist handouts
- Immobilized enzymes are widely used in industry
- Application: Methods of production of lactose-free milk and its advantages.
- Metabolic pathways consist of chains and cycles of enzyme-catalysed reactions.
- Enzyme inhibitors can be competitive or non-competitive.
- Metabolic pathways can be controlled by end-product inhibition.
- Application: End-product inhibition of the pathway that converts threonine to isoleucine.
- Skill: Design of experiments to test the effect of temperature, pH and substrate concentration of the activity of enzymes.
- Data Analysis Practice 2 (Due beginning of class)
11/16 & 11/19
- Review: End product inhibition
- Grade Data Analysis 2
- Anti-Material drugs databases
- Distinguish types of inhibition from graphs
- Analysis of enzyme graphs and data
- Enzyme Lab write up
- Calculate reaction rates
- Application: Use of databases to identify potential new anti-material drugs.
- Skill: Calculating and plotting rates of reaction from raw experimental results.
- Skill: Distinguishing different types of inhibition from graphs at specified substrate.
Study for Assessment
Molecular Biology Assessment Retakes Due 11/20
11/20 & 11/21
- Proteins Assessment
- Complete Lab