Integrative Bioinformatics 2018      #IBUK2018

Rothamsted Research, Harpenden, AL5 2JQ, UK

http://ib2018.eventzilla.net/ 

PROGRAMME

Wednesday June 13

9:30

Registration

Room 104

Room 102 & 103

10:00

11:30

coffee

Workshop 1 - FAIR data management for plant genomics & phenomics

  • Matthias Lange (IPK)
  • Daniel Arend (IPK)
  • Cyril Pommier (INRA URGI)

Workshop 3 - Protein Structure Prediction, Molecular Visualisation and Variant Analysis

  • Lawrence Kelley (ICL)
  • Charles Ofoegbu (ICL)
  • Michael Sternberg (ICL)

13:00

Lunch break

14:00

15:30

coffee

Workshop 2 - Connecting the dots in life science data

  • Keywan Hassani-Pak (RRes)
  • Marco Brandizi (RRes)
  • Mark Needham (Neo4j)
  • Kevin Dialdestoro (Genestack)

Workshop 4 - COPO and Grassroots – a portal for plant scientists to describe, store and retrieve data more easily

  • Toni Etuk (Earlham)
  • Simon Tyrrell (Earlham)

18:00

Pub social in Harpenden Arms

Thursday June 14

9:00

Registration

9:30

Welcome

  • Chris Rawlings (Rothamsted Research)

Session 1: Bioinformatics resources for gene discovery

  • Chair: Keywan Hassani-Pak

9:45

Keynote address: CATH Functional Families to Predict Protein Functions and Track Evolution

  • Christine Orengo (University College London)

10:30

InterMine past, present and future

  • Gos Micklem (Cambridge University)

11:00

Coffee break (30 minutes)

11:30

Phyre and PhyreRisk – Integrating genetic variant data with experimental and predicted protein structures and their complexes

  • Michael Sternberg (Imperial College London)

11:50

KnetMiner - exploratory data mining and gene discovery using genome-scale knowledge networks

  • Ajit Singh (Rothamsted Research)

12:10

Modeling and simulating aerobic carbon metabolism of green microalga using Petri-nets and VANESA

  • Christoph Brinkrolf (Bielefeld University)

12:30

Beyond the one-way ANOVA for 'omics data

  • Kirsty Hassall (Rothamsted Research)

12:45

Pathogen-Host Interactions database

  • Martin Urban (Rothamsted Research)

12:55

How can you show off your data?

  • Philip Dooner (F1000 Research)

13:05

Lunch break (1.5 hours)

Including opportunity for poster presentation and software demos

Session 2: Multi-omics and systems biology

  • Chair: Uwe Scholz

14:30

Keynote address: Computational methods for analyzing large collections of single cell RNA-seq datasets

  • Martin Hemberg (Wellcome Sanger Institute)

15:15

Multi-layered networks – an integrative and system-specific approach to understand complex diseases

  • Tamas Korcsmaros (Earlham Institute)

15:45

Developing approaches for integrative view on regulatory mechanisms involved in molecular interspecies communications

  • Ekaterina Shelest (German Centre for Integrative Biodiversity Research)

16:00

Coffee break (30 min)

16:30

Understanding the organization principles of Rho GTPase Signaling through a systems analysis of RhoGEF/RhoGAP regulators

  • Evangelia Petsalaki (EMBL-EBI)

17:00

Multi-omic dissection and prediction of complex traits in plants

  • Gancho Slavov (Rothamsted Research)

17:20

BioModelKit - An Integrative Framework for Multi-Scale Biomodel-Engineering

  • Mary-Ann Blaetke (IPK Gatersleben)

17:40

Applying computer vision and machine learning to address the pressing challenges of modern plant phenotyping

  • Pouria Sadeghi-Tehran (Rothamsted Research)

18:00

Visit a modern field phenotyping platform and world’s longest running experiment

19:00

Reception and dinner party at Rothamsted Manor

22:00

Taxis depart to Hotels

Friday June 15

Session 3: From FAIR data to knowledge graphs to AI

  • Chair: Chris Rawlings

9:30

Keynote address: From Text to Data to the World – The Future of Knowledge Graphs

  • Paul Groth (Elsevier Labs)

10:15

Deep Learning and Artificial Intelligence platforms, the future is amazing!

  • Lee Rossiter (Novatech)

10:45

Towards FAIRer Biological Knowledge Networks using a hybrid Linked Data and Graph Database approach

  • Marco Brandizi (Rothamsted Research)

11:05

Coffee break (25 minutes)

11:30

Stepping the stones and exploring the paths, lessons from Open PHACTS and WikiPathways

  • Chris Evelo (Maastricht University)

12:00

Semantics as a service

  • Simon Jupp (EMBL-EBI)

12:20

FAIR URIs for Data Integration Platforms

  • Justin Clark-Casey (Cambridge University)

12:35

Machine learning-driven analysis of biological networks for predictive modelling of drug toxicity

  • Artem Lysenko (RIKEN)

12:50

A dive into automating food quality assessment, using cloud computing and machine learning

  • Emma Sims (Cranfield University)

13:00

Lunch break (1 hour)

Session 4: Better software, better research

  • Chair: Ralf Hofestaedt

14:00

Keynote address: Better software, better services, better research: SSI, ELIXIR and you

  • Carole Goble (ELIXIR UK and SSI)

14:45

Galaxy and beyond

  • Björn Gruening (Freiburg University)

15:15

Immersive Analytics in Integrative Bioinformatics

  • Björn Sommer (Konstanz University)

15:30

A User Experience Toolkit for Life Sciences

  • Jennifer Cham (European Bioinformatics Institute)

16:00

Close and Depart


Workshop 1

FAIR Data Management for Plant Genomics & Phenomics: Standards, Tools and Infrastructures

10:00

Standards for distributed plant data integration: challenges and solutions

  • Cyril Pommier (INRA-URGI, France)

10:20

Publish and share primary research data: use case plant phenomics data

  • Matthias Lange (IPK, Germany)

10:40

e!DAL - a Comprehensive Infrastructure to FAIRly Store & Publish Research Data

  • Daniel Arend (IPK, Germany)

11:30

Coffee break (15 minutes)

11:45

WheatIS and ELIXIR plant data discovery

  • Cyril Pommier (INRA-URGI, France)

13:00

Lunch break (one hour)

Workshop 2

Connecting the dots in Life Sciences: data integration, knowledge graphs and the KnetMiner use case

14:00

Setting the scene: introduction to data integration and KnetMiner

  • Keywan Hassani-Pak (Rothamsted Research)

14:30

Behind the scenes of KnetMiner: towards standardised and interoperable knowledge graphs

  • Marco Brandizi (Rothamsted Research)

15:30

Coffee break (15 minutes)

15:45

Neo4j graph database - Introduction to Neo4j, Cypher and latest developments

  • Mark Needham (Neo4j)

16:30

Genestack - Deploying private KnetMiner Servers in the cloud

  • Kevin Dialdestoro (Genestack)

17:00

Open Discussion

18:00

Pub social in Harpenden Arms

Workshop 3

Protein Structure Prediction, Molecular Visualisation and Variant Analysis using Phyre, EzMol and PhyreRisk

10:00

Phyre presentations

  • Lawrence Kelly (Imperial College London)

11:30

Coffee break (15 minutes)

11:45

EzMol presentations

  • Michael Sternberg (Imperial College London)

12:00

PhyreRisk presentations

  • Charles Ofoegbu (Imperial College London)

12:15

Attendees explore tools

13:00

Lunch break (one hour)

Workshop 4

COPO and Grassroots – a portal for plant scientists to describe, store and retrieve data more easily

14:00

COPO and Grassroots presentations

  • Toni Etuk (Earlham)
  • Simon Tyrrell (Earlham)

15:30

Coffee break (20 minutes)

15:45

Attendees explore tools

17:00

Open Discussion

18:00

Pub social in Harpenden Arms