Friday 15th October |
10:00 – 15:00 | Registration – Poster mounting |
11:00 – 14:00 | Workshop IUCr sponsored Bernhard Lohkamp Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Sweden Macromolecular model building and validation Chairperson: George Kontopidis |
15:00 – 15:30 | Opening Session WELCOME & OPENING REMARKS |
1st Session | Structures of Biological Macromolecules/Structure-based design Chaipersons: Spyros Zografos, Vicky Skamnaki |
15:30 – 16:15 | Remote Keynote Lecture Janet Thornton, European Bioinformatics Institute-EBI-EMBL “Using 3D structural data to interpret the impact of variants for health and disease” |
16:15 – 16.45 | Invited Lecture Demetres Leonidas, Dept. of Biochemistry and Biotechnology, University of Thessaly “The structural unraveling of the mysterious function of human angiogenin” |
16:45 – 17:15 | Invited Lecture Nikos Pinotsis, Birkbeck College, University of London, UK “Mitochondrial respiratory super-complexes” |
17:15 – 17:45 | COFFEE BREAK |
2nd Session | Structures of Biological Macromolecules/Structure-based design Chaipersons: Spyros Zografos, George Kontopidis |
17:45 – 18:30 | Keynote - IUCr sponsored Lecture Bernhard Lohkamp, Dept. of Medical Biochemistry and Biophysics, Karolinska Institutet, Sweden “Coot I: Refinement and Ligands in Coot” |
18:30 – 19:00 | Remote Lecture Paul Emsley, MRC Laboratory of Molecular Biology, Cambridge, UK “Coot II: Advanced Coot tools: Carbohydrates and cryo-EM” |
19:00 – 19:30 | Remote Keynote Lecture Martin Caffrey, Laboratory of Membrane Structural & Functional Biology, University of Dublin, Ireland "Lipid Mesophases for Membrane Protein Structure, Function and Drug Design Studies" |
| Saturday 16th October |
3rd Session | Structures of Biological Macromolecules/Structure-based design Chaipersons: Athanasios Papakyriakou, Efstratios Stratikos |
9:30 – 9:45 | Short talk Anastasia Mpakali, National Centre for Scientific Research “Demokritos”, Athens, Greece “Inhibitor-dependent usage of the P1’ specificity pocket of ER aminopeptidase 2” |
9:45 – 10:00 | Short talk Petros Giastas, Biotechnology Dept., Agricultural University of Athens, Greece “Structural determinants for the selective interaction of α-Conotoxins with the α9/α10 nicotinic acetylcholine receptor” |
10:00 – 10:30 | Invited Lecture Marios Zouridakis, Dept. of Neurobiology, Hellenic Pasteur Institute, Athens, Greece “Co-crystal structures of the extracellular domain of human ACE2 receptor with the SARS-CoV2 receptor binding domain of Wuhan and three other variants of concern” |
10:30 – 10:45 | Short talk Eftichia Kritsi, Institute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece "Discovery of novel epigenetic inhibitors: A computational approach" |
10:45 – 11:00 | Short talk Emmanuel Saridakis, Institute of Nanoscience and Nanotechnology, National Center for Scientific Research “Demokritos”, Athens, Greece “A novel, four subunit, “dimer-within-a-dimer” γ-cyclodextrin self-assembly” |
11:00 – 11:15 | Presentation Sponsored by Anelis & RIGAKU Felix Hennersdorf, Rigaku Corporation “The latest range of Rigaku Oxford Diffraction instrument configurations for structural biology - example applications” |
11:15 – 11:45 | COFFEE BREAK – POSTER SESSION I |
4th Session | Characterization of materials (small molecules / inorganics) - structure and properties Chaipersons: Vassilis Psycharis, Catherine Raptopoulou |
11:45 – 12:30 | Keynote Lecture George Christou, Dept. of Chemistry, University of Florida, USA “Molecular Nanoparticles: A Molecular Route to Ultra-small Nanoparticles of Important Metal Oxides” |
12:30 – 13:00 | Invited Lecture Spyros Perlepes, Dept. of Chemistry, University of Patras, Greece “Single-Crystal X-Ray Crystallography of Small Inorganic Molecules: Quo Vadis?” |
13:00 – 13:30 | Invited Lecture Panayotis Kyritsis, Dept. of Chemistry, National and Kapodistrian University of Athens, Greece “Structural basis of chemical properties in certain transition metal complexes” |
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13:30 – 14:30 | LUNCH BREAK – POSTER SESSION II - General Assembly of HeCrA |
5th Session | Characterization of materials (small molecules / inorganics) - structure and properties Chaipersons: Spyros Perlepes, Panayotis Kyritsis |
14:30 – 14:45 | Short talk Dimitris Kalofolias, Institute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece "X-ray analysis of the mycotoxin Isororidin A" |
14:45 – 15:00 | Short talk Theocharis Stamatatos, Chemistry Department, University of Patras, Greece “‘New’ Coordination Chemistry with ‘No’ Organic Chelate Ligands: A Route to Structurally and Magnetically Interesting 3d-Metal Clusters and Coordination Polymers” |
15:00 – 15:30 | Invited Lecture Catherine Raptopoulou, Institute of Nanoscience and Nanotechnology, National Center for Scientific Research Demokritos, Athens, Greece “Iron molecular magnetic materials based on polydentate ligands” |
15:30 – 16:00 | Invited Lecture Sotiris Hadjikakou, Lab. of Biological Inorganic Chemistry, Dept. of Chemistry, University of Ioannina, Greece “Drug activation for the discovery and development of new targeted chemotherapeutic formulations” |
16:00 – 16:15 | Short talk Marianna Danopoulou, Department of Chemistry, National and Kapodistrian University of Athens, Athens, Greece “Structural Characterization of Open-Shell Cr(II) Three-Coordinated Paramagnetic Complexes with N-Heterocyclic Carbenes” |
16:15 – 16:30 | Short talk Vassilis Panagopoulos, Institute of Nanoscience and Nanotechnology, NCSR Demokritos, Athens, Greece “Nanosized phase separation in LiFe5-xMnxO8” |
16:30– 17:00 | COFFEE BREAK – POSTER SESSION III |
6th Session | Other biophysical methods and hybrid approaches Chairpersons: Kostas Bethanis, Vassiliki Iconomidou |
17:00 – 17:45 | Remote Keynote Lecture - EBSA sponsored Lecture Anthony Watts, Department of Biochemistry, University of Oxford “New mechanistic insights into the high efficiency of Archaerhodopsins” |
17:45 – 18:15 | Invited Lecture Maria Katsikini, School of Physics, Aristotle University of Thessaloniki, Greece “EXAFS: study of deviations from perfect crystallinity” |
18:15 – 18:45 | Remote Lecture Achilleas Lazarides, Dept. of Mathematical Sciences, University of Loughborough, UK “Time Crystals: What they are and what they are not” |
18:45 – 19:00 | Short talk Maria Chrysina, Institute of Nanoscience and Nanotechnology, NCSR “Demokritos”, Athens, Greece “HYSCORE spectroscopy as an alternative tool in the study of systems that are not feasible to crystallize: the example of the stable Tyrosyl D radical of Photosystem II” |
19:00 – 19:15 | Short talk Dionysios Neofytos, Institute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece “Biophysical characterization of the synthetic polyelectrolyte QPDMAEMA interactions with the enzyme Glycogen Phosphorylase in aqueous solutions” |
| Sunday 17th October |
7st Session | Other biophysical methods and approaches Chairpersons: Konstantina Yannakopoulou, Maria Zervou |
9:30 – 9:45 | Short talk Eleanna Christodoulou, Institute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece “Investigation of volatile metabolites from marine organisms as potential repellents: Fluorescence and NMR spectroscopy studies of their binding to Odorant Binding Proteins of the mosquito Anopheles gambiae” |
9:45 – 10:00 | Short talk Christina Mountaki, Institute of Biosciences and Applications, National Center for Scientific Research “Demokritos”, Athens, Greece "Natural polar phenols target the structure and functions of apoE4 forms related to Alzheimer’s disease pathogenic processes" |
10:00 – 10:30 | Invited Lecture Panagis Filippakopoulos, Nuffield Department of Medicine, University of Oxford "Control of gene expression via targeting of transcriptional scaffolding" |
10:30 – 11:00 | Invited Lecture Vassiliki Iconomidou, Department of Biology, National and Kapodistrian University of Athens, Greece “Towards Understanding Amyloid structures in Human Diseases” |
11:00 – 11:30 | COFFEE BREAK – POSTER SESSION IV |
8th Session | Other biophysical methods and approaches Chairpersons: Petros Giastas, Emmanuel Saridakis |
11:30 – 12:15 | Keynote Lecture Juha Huiskonen, Helsinki Institute of Life Science HiLIFE, Finland “Towards structures of endogenous complexes by cryo-EM” |
12:15 – 12:45 | Invited Lecture Nicolaos Sgourakis, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA “Dynamics of MHC-I Molecules in the Antigen Processing and Presentation Pathway” |
12:45 – 13:00 | Short talk Marilena Theodoropoulou, Department of Biology, National and Kapodistrian University of Athens, Greece “The immunological factor a2-macroglobulin is involved in Aβ oligomerization process in Alzheimer’s Disease” |
13:00 – 13:15 | Remote Presentation Sponsored by Anelis & Douglas Instruments Patrick Stewart, Douglas Instruments, UK “Introduction to Oryx: rMMS microseeding and charactarising samples for cryoEM” |
13:15 – 13:30 | Evangelia Chrysina, National Hellenic Research Foundation, Greece "Inspired-RIs, The National Research Infrastructures on Integrated Structural Biology, Drug Screening Efforts & Drug Target Functional Characterization" |
13:30 – 14:00 | HeCrA Ceremony in honor of retired members - “Nikos OIKONOMAKOS” award giving - Closing remarks |
