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Animesh

Sharma

Born on 14th Jan 1977

Mobile:

+47-46771250

Residence:

Jørunds gate 1,

Trondheim 7030,

Norway

Office:

http://www.ntnu.edu/employees/animesh.sharma 

Email:

sharma.animesh@gmail.com 

animesh.sharma@ntnu.no 

LinkedIn:

https://www.linkedin.com/in/animeshsharma1977/ 

animesh (Ani) · GitHub 

β.Log [ Computational Biology News ]

EDUCATION

  • Aug 2001 - May 2002, School of Information Technology, Jawaharlal Nehru University, India, A.P.G.D. Bioinformatics (Advanced Post Graduate Diploma in Bioinformatics).
  • Aug 1995 - Feb 2001, Maulana Azad Medical College, Delhi University, India, M.B.B.S. (Bachelor of Medicine and Surgery).

EXPERIENCE

  • Sep 2012 - Current: Senior Engineer, St. Olav Hospital, Norwegian University of Science and Technology, NO-7491 Trondheim Norway
  • Mass spectrometry based high throughput Protein sequencing
  • Dec 2011 - March 2012: Research fellow, Bergen fMRI group (http://fmri.uib.no/), Department of Biological and Medical Psychology, University of Bergen.
  • Functional magnetic resonance imaging & neuroinformatics
  • 454 high throughput Genome sequencing and assembly
  • Assisting in programming paradigms course
  • Machine learning based speech analysis & health informatics
  • Gene expression data classification, Promoter Prediction, and Protein Folding analysis.
  • April 2003 - June 2004, Associate Consultant, Infosys Technologies Limited, Bangalore, India, http://www.infosys.com 
  • Consultation over Oracle Clinical ver. 4.5 for major Pharmaceutical and Clinical trial management companies; Installed and maintained 8 nodes Dell Cluster running Red Hat Linux 9.0 with MPI based namd-charmm++ and ClustalW; Design and implementation of 'Doctors database' streamlining process of doctor's enrolment in clinical trials; Data Integration & Knowledge Management for Life Sciences, GPCR as case study; ECG dashboard for a client which gives easy access to critical information such as status of the clinical trial pertaining to ECG of subjects enrolled in trial
  • Member of designing and testing team for windows based application EXOME to do basic sequence analysis (DNA and protein) and OncoMaster, an Integrated Information Suite of Cancer Gene, designed to demonstrate the capability of Integrated Databases for Cancer Research and Development.

AWARDS

National

  • Scholarship from Department of Biotechnology, India [2001-2002]
  • Mascon fellowship, India [2002]
  • Rank 13 in medical entrance examination (Delhi, overall India 114) [1995]
  • State Level (U.P.) Mathematics Olympiad, India [1993].

International

  • Norwegian language certification from Municipal Corporation of Bergen, Norway [2012]
  • Travel allowance from J. Craig Venter Institute, Rockville, MD, U.S.A. [2010]
  • Molecular and Computational Biology Fellowship, University of Bergen, Norway [2010]
  • Graduate research assistance-ship from University of Missouri - Kansas City, U.S.A. [2005]

SKILLS

Computational

  • Programming/scripting in PERL, Matlab, R, and Python
  • Linux based high performance computing administration

Domain-specific

  • High throughput genome and proteome sequencing and  assembly
  • Gene/Protein sequence, structure and expression analysis
  • fMRI and EEG data analysis,
  • Machine Learning
  • Medical diagnoses
  • Registered medical practitioner, Delhi Medical Council (DMC/R/00534), India

PATENT

Pat1092/DEL/2007-Indian Patent- Insecticidal XnGroEL protein of Xenorhabdus nematophila

PUBLICATIONS & ACADEMIC ACTIVITIES

Complete list at https://www.researchgate.net/profile/Animesh-Sharma-3/research

Specificaly this year, co-authoring following 6 articles indexed in PubMED, published in high impact (IF>4) journals:

1. ALKBH3 partner ASCC3 mediates P-body formation and selective clearance of MMS-induced 1-methyladenosine and 3-methylcytosine from mRNA. Wollen KL, Hagen L, Vågbø CB, Rabe R, Iveland TS, Aas PA, Sharma A, Sporsheim B, Erlandsen HO, Palibrk V, Bjørås M, Fonseca DM, Mosammaparast N, Slupphaug G. J Transl Med. 2021 Jul 3;19(1):287. doi: 10.1186/s12967-021-02948-6. PMID: 34217309.

2. Cancer-induced muscle atrophy is determined by intrinsic muscle oxidative capacity. Alves CRR, Eichelberger EJ, das Neves W, Ribeiro MAC, Bechara LRG, Voltarelli VA, de Almeida NR, Hagen L, Sharma A, Ferreira JCB, Swoboda KJ, Slupphaug G, Brum PC.FASEB J. 2021 Jul;35(7):e21714. doi: 10.1096/fj.202100263R. PMID: 34118107

3. Nucleoside Analogues Are Potent Inducers of Pol V-mediated Mutagenesis. Sumabe BK, Ræder SB, Røst LM, Sharma A, Donkor ES, Mosi L, Duodu S, Bruheim P, Otterlei M. Biomolecules. 2021 Jun 5;11(6):843. doi: 10.3390/biom11060843. PMID: 34198819.

4. HDACi mediate UNG2 depletion, dysregulated genomic uracil and altered expression of oncoproteins and tumor suppressors in B- and T-cell lines. Iveland TS, Hagen L, Sharma A, Sousa MML, Sarno A, Wollen KL, Liabakk NB, Slupphaug G. J Transl Med. 2021 Jun 4;19(1):243. doi: 10.1186/s12967-021-02896-1. PMID: 34088330.

5. Long-Term Exposure to Nanosized TiO2 Triggers Stress Responses and Cell Death Pathways in Pulmonary Epithelial Cells. Alswady-Hoff M, Erdem JS, Phuyal S, Knittelfelder O, Sharma A, Fonseca DM, Skare Ø, Slupphaug G, Zienolddiny S. Int J Mol Sci. 2021 May 19;22(10):5349. doi: 10.3390/ijms22105349. PMID: 34069552.

6. Functional studies of CpSRP54 in diatoms show that the mechanism of thylakoid protein insertion differs from that in plants and green algae. Nymark M, Grønbech Hafskjold MC, Volpe C, Fonseca DM, Sharma A, Tsirvouli E, Serif M, Winge P, Finazzi G, Bones AM. Plant J. 2021 Apr;106(1):113-132. doi: 10.1111/tpj.15149. Epub 2021 Feb 16.PMID: 33372269

 

Further I have been delivering and assisting MOL3007 and MOL3021/3022 in some of their lectures and training respectively to Master/PhD students and assisting them in their thesis/manuscripts within Norwegian University of Science and Technology.

 

I have also taken/contributed to several initiative even outside my stated job, like being part of the local organizing committee of "International NTNU Symposium on Clinical Biomarkers of Cancer" https://cancerbiomarkerstrondheim.org/faculty. I have also been active member of social events organized by the department.