VEERABHADRAN (VEERA) BALADANDAYUTHAPANI, PH.D.
CONTACT INFORMATION |
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Department of Biostatistics Room 4208, 1415 Washington Heights Ann Arbor, Michigan 48109 | 734-764-5702 [phone] 734-763-2215 [fax] veerab@umich.edu Website: bayesrx.com GitHub: bayesrx |
PROFESSIONAL APPOINTMENTS AND ACADEMIC EXPERIENCE
2025+ Jeremy M.G. Taylor Collegiate Professor
2024+ Chair
Department of Biostatistics, School of Public Health
2018+ Professor (tenured)
Department of Biostatistics, School of Public Health (primary)
Gilbert S. Omenn Department of Computational Medicine and Bioinformatics (joint)
2024+ Associate Director, Quantitative Data Sciences
2020+ Director, Cancer Data Science Shared Resource
Rogel Cancer Center
University of Michigan Medical School | Rogel Cancer Center
2017 – 2018 Professor (tenured)
2012 – 2017 Associate Professor (tenured) and Institute Faculty Scholar (2014-2017)
2005 – 2012 Assistant Professor (tenure-track)
Department of Biostatistics
The University of Texas M. D. Anderson Cancer Center, Houston, TX
2005 – 2018 Assistant/Associate/Full Professor (adjunct)
Department of Statistics, Texas A&M and Rice University, TX
Department of Biostatistics, UT School of Public Health, Houston, TX
2000 – 2005 Instructor, Graduate Research Assistant and Predoctoral trainee,
Training Program in Bioinformatics, Dept. of Statistics, Texas A&M University
EDUCATION
2005 Ph.D., Statistics, Dept. of Statistics, Texas A&M University
- Dissertation Topic: Bayesian Methods in Bioinformatics
- Major Advisors: Raymond J. Carroll & Bani K. Mallick
- Dean’s Graduate Merit Scholarship; Graduate Endowment Fellowship
2000 M.A., Statistics, Dept. of Biostatistics, University of Rochester, Rochester, NY
1999 B.Sc. (Honors), Mathematics, Indian Institute of Technology (IIT), Kharagpur, India
VISITING/OTHER APPOINTMENTS
2010 Visiting Assistant Professor
School of Mathematics, Statistics & Actuarial Science University of Kent, Canterbury, UK
Department of Statistics and Oxford Centre for Gene Function University of Oxford, Oxford, UK
RESEARCH INTERESTS
THEORY AND METHODS: Bayes; big data, health data science, functional data, graphical models, integrative modeling, machine learning, nonlinear/nonparametric models, spatial data, statistical computing
APPLICATIONS: Cancer, spatial biology, high-throughput genomics, epigenomics, transcriptomics and proteomics, high-resolution neuro- and cancer- imaging, clinical trials, precision medicine
HONORS AND AWARDS
Jeremy M. G. Taylor Collegiate Professorship, University of Michigan, 2025
Andrei Yakovlev Colloquium Speaker, University of Rochester, 2025
Fellow, American Association for Advancement in Science, 2022
Young Alumni Achiever Award, Indian Institute of Technology, Kharagpur, 2020
Myrto Lefkopoulou Distinguished Lectureship, Harvard School of Public Health, 2019
H. O. Hartley Award, Dept. of Statistics, Texas A&M University, 2018
Annual Theodore G. Ostrom Lecturer, Washington State University, 2018
Fellow, American Statistical Association, 2016
Elected Member, International Statistical Institute, 2016
Faculty Scholar Award, UT MD Anderson Cancer Center, 2014
Keynote Speaker, Genome Engineering for Cancer Treatment, Canberra, Australia, 2017
Young Researcher Award, International Indian Statistical Association, 2015
Highlighted newsworthy oral presentation at the Radiological Society of North America Annual Meetings, 2015
Selected participant, SAMSI Innovations Lab in Big Data and Precision Medicine, 2015
Biometrics Editor’s Invited Paper, Joint Statistical Meetings, 2007
New Researchers Presentation, Ninth Case Studies in Bayesian Analysis Meeting, 2007
Best Graduate Student Presentation, Student Research Week, Texas A&M University, 2004
AUF Graduate Endowment Fellowship, Texas A&M University, 2003
Emanuel Parzen Graduate Research Fellowship Award, Texas A&M University, 2003.
R. L. Anderson Best Student Paper Award, SRCOS, 2003
Best Student Poster, Conference of Texas Statisticians, Texas A&M University, 2003
SPES Student Scholarship, Joint Statistical Meetings, Atlanta, 2001
Dean’s Graduate Merit Scholarship, Texas A&M University, 2000
Mobile Aggie Merit Fellowship, Texas A&M University, 2000
Graduate Fellowship, University of Rochester, 1999
PROFESSIONAL MEMBERSHIPS
Fellow, American Association for the Advancement of Science (AAAS)
Fellow, American Statistical Association (ASA)
Elected Member, International Statistical Institute (ISI)
Institute of Mathematical Statistics (IMS)
International Biometric Society Eastern North American Region (ENAR) International Society for Bayesian Analysis (ISBA)
International Indian Statistical Association (IISA)
BOOKS
- Mallick, B. K., Gold, D. L. and Baladandayuthapani, V. (2009). Bayesian Methods for Gene Expression Data. Wiley, U.K.
PUBLICATIONS
* = student/postdoctoral trainee
- Baladandayuthapani, V., Mallick, B. K., and Carroll, R.J. (2005). Spatially adaptive Bayesian penalized regression splines (p-splines). Journal of Computational and Graphical Statistics, 14, 378-394. https://doi.org/10.1198/106186005X47345
- Phadke, A. P., de la Concha-Bermejillo, A., Wolf, A. M., Andersen, P. R., Baladandayuthapani, V., and Collison, E. W. (2006). Pathogenesis of a Texas feline immunodeficiency virus isolate: an emerging subtype of clade b, Veterinary Microbiology, 115, 64-76. https://doi.org/10.1016/j.vetmic.2006.02.012
- Nehete, P. N., Nehete, B. P., Hill, L., Manuri, P. R., Baladandayuthapani, V. , Feng, L., Simmons, J., and Sastry, K. J. (2007) Selective induction of cell-mediated immunity by prophylactic vaccination with a conserved HIV-1 envelope peptide-cocktail for protection of rhesus macaques from chronic SHIVKU2 infection. Virology, 370(1):130-41. https://doi.org/10.1016/j.virol.2007.08.022
- Aggrawal, B. B., Sethi, G., Baladandayuthapani, V., Krishnan, S., and Sishodia, S. Targeting cell signaling pathways for drug discovery: an old lock needs a new key (2007). Journal of Cellular Biochemistry, 102(3):580-92. https://doi.org/10.1002/jcb.21500
- Baladandayuthapani, V., Mallick, B. K., Hong, M. Y., Lupton, J. R., Turner, N. D. and Carroll, R. J. (2008). Bayesian hierarchical spatially correlated functional data analysis with application to colon carcinogenesis. Biometrics. 64, 64-73 [Biometrics Editor’s Invited Paper for JSM 2007]. https://doi.org/10.1111/j.1541-0420.2007.00846.x
- Hong, M. Y., Baladandayuthapani, V., Li, Y., Carroll, R. J., Turner, N. D., and Lupton, J. R. (2008) Coordinated p27 Kip1 expression as a function of distance between crypts - potential inter-crypt signaling. The FASEB Journal, 22:865.4.
- Zhang, N., Ge, G., Meye, R., Sethi, S., Basu, D., Pradhan, S., Zhao, Y.J., Li, X.N., Cai, W. W., El-Naggar, K. A., Baladandayuthapani, V., Kittrell, F. S., Rao, P. H., Medina, D., and Pati, D. (2008). Overexpression of Separase induces aneuploidy and mammary tumorigenesis. Proceedings of National Academy of Sciences, USA 105(35):13033-8. https://doi.org/10.1073/pnas.080161010
- Nanda, U., Eisen, S. J., and Baladandayuthapani, V. (2008) Undertaking an art-survey to compare patient vs. student art preferences. Journal of Environment Behavior, 40, 269-301. https://doi.org/10.1177/0013916507311
- Wang J., Xu, J., and Baladandayuthapani, V. (2009) Contrast sensitivity of digital imaging display systems: contrast threshold dependency on object type and implications for monitor quality assurance and quality control in PACS. Medical Physics, 36(8) 3682-3292. https://doi.org/10.1118/1.3173816
- Zhou L., Huang J. Z., Martinez J. G., Maity A., Baladandayuthapani, V. and Carroll R. J. (2010) Reduced rank mixed effects models for spatially correlated hierarchical functional data. Journal of the American Statistical Association, 105 (49) 390-400. https://doi.org/10.1198/jasa.2010.tm08737
- Baladandayuthapani, V., Ji. Y., Talluri, R., Nieto-Barajas, L. E. and Morris J. S. (2010) Bayesian Random Segmentation Models to Identify Shared Copy Number Aberrations for Array CGH Data. Journal of American Statistical Association 105(492): 1358-1375. https://doi.org/10.1198/jasa.2010.ap09250
- Morris J. S., Baladandayuthapani, V., Herrick R. C. and Gutstein H. Automated functional mixed models and isomorphic basis-space modeling, with application to proteomics data. Annals of Applied Statistics 5(2A):894-923. https://doi.org/10.1214/10-AOAS407
- Lin, Y.X., Baladandayuthapani, V., Bonato, V., and Do, K.A. (2010) Estimating shared copy number aberrations for array CGH data: the linear-median method. Cancer Informatics, 9 229-249. https://doi.org/10.4137/CIN.S5614
- Navas, M.*, Ordonez C., and Baladandayuthapani, V.. (2010) On the computation of stochastic search variable selection in linear regression with UDFs. Proc. IEEE ICDM Conference, p. 941-946, 2010. 941-946. https://doi.org/10.1109/ICDM.2010.79
- Navas, M.*, Ordonez C. and Baladandayuthapani, V. (2011) Fast PCA and Bayesian variable selection for large data sets based on SQL and UDFs. Proc. ACM KDD Workshop on Large-scale Data Mining: Theory and Applications (LDMTA, KDD Conference Workshop)
- Bonato V.*, Baladandayuthapani, V., Broom, B. M., Sulman E. P., Aldape K. D and Do, K.A. (2010)
Bayesian ensemble methods for survival prediction in gene expression data. Bioinformatics, 27(3):359-67. https://doi.org/10.1093/bioinformatics/btq660
- Jones, R. J., Baladandayuthapani, V., Neelapu, S., Sharma, R. ,Fayad, L., Romaguera, J. E., Wang, M., Yang, D. and Orlowski, R. Z. (2011) HDM-2 inhibition suppresses expression of ribonucleotide reductase subunit M2, and synergistically enhances gemcitabine-induced cytotoxicity in mantle cell lymphoma. Blood, 118(15): 4140-9. https://doi.org/10.1182/blood-2011-03-340323
- Thompson, P. A., Brewster A., Broom B., Do, K. A., Baladandayuthapani, V., Edgerton, M., Hahn, K., Murray, J., Sahin, A., Tsavachidis, S., Wang, Y., Zhang, L., Hortobagyi, G., Mills, G. and Bondy, M. (2011) Selective genomic copy number imbalances and probability of recurrence in early- stage breast cancer. PLos One, 6(8): e23543. https://doi.org/10.1371/journal.pone.0023543
- Zheng, Y., Yang, J., Qian, J., Zhang, L., Lu, Y., Li, H., Lan, Y., Liu, Z., He, J., Hong, S., Thomas, S., Shah, J., Baladandayuthapani, V., Kwak, L. W., and Yi. Q. (2012) Novel phosphatidylinositol 3-kinase inhibitor NVP-BKM120 induces apoptosis in myeloma cells and shows synergistic anti-myeloma activity with dexamethasone. Journal of Molecular Medicine, 90(6): 695-706. https://doi.org/10.1007/s00109-011-0849-9
- Hrafnkelsson, B., Morris J. S., and Baladandayuthapani, V.. Spatial modeling of annual minimum and maximum temparture in Iceland. Meteorology and Atmospheric Physics, 116: 43-61.
- Garrett, C. R., Hassabo, M. H., Bhadkamkar, N. A., Wen, S., Baladandayuthapani, V., Kee, K. K., and Hassan, M. H. (2012) Survival advantage observed with the use of metformin in patients with type II diabetes and colorectal cancer. British Journal of Cancer, 106(8): 1374-1378. https://doi.org/10.1038/bjc.2012.71
- Garrett, C.R., George, B., Viswanathan, C., Bhadkamkar, N.A., Wen, S., Baladandayuthapani, V., You, Y.N., Kopetz, E.S., Overman, M.J., Kee, B.K., and Eng, C. (2012) Survival benefit associated with surgical oophorectomy in patients with colorectal cancer metastatic to the ovary. Clinical Colorectal Cancer, 11(3) 191-4. https://doi.org/10.1016/j.clcc.2011.12.003
- Prasad, S., Yadav, V.R., Sung, B., Reuter, S., Kannappan, R., Deorukhkar, A., Diagaradjane, P., Wei, C., Baladandayuthapani, V., Krishnan, S., Guha, S., and Aggarwal, B.B. (2012) Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine. Clinical Cancer Research, 18(18): 4942-53. https://doi.org/10.1158/1078-0432.ccr-11-2805
- Jones, R.J., Bjorklund, C.C., Baladandayuthapani, V., Kuhn, D.J. and Orlowski, R.Z. (2012) Drug resistance to inhibitors of the human double minute-2 E3 ligase is mediated by point mutations of p53, but can be overcome with the p53 targeting agent RITA. Molecular Cancer Therapy, 11(10): 2243-53. https://doi.org/10.1158/1535-7163.mct-12-0135
- Kuhn, D.J., Berkova, Z., Jones, R.J., Woessner, R., Bjorklund, C.C., Ma, W., Davis, R.E., Lin, P., Wang, H., Madden, T.L., Wei, C., Baladandayuthapani, V., Wang, M., Thomas, S.K., Shah, J.J., Weber, D.M. and Orlowski, R.Z. (2012) Targeting the insulin-like growth factor-1 receptor to overcome bortezomib resistance in preclinical models of multiple myeloma. Blood, 120(16): 3260-3270. https://doi.org/10.1182/blood-2011-10-386789
- Garcia-Alvarado, C.*, Ordonez, C., and Baladandayuthapani, V. (2012) Querying external source code files of programs connecting to a relational database. Proc. ACM Ph.D. Workshop on Information and Knowledge Management (PIKM, CIKM Conference Workshop).
- Jennings, E.*, Morris, J.S., Carroll, R., Manyam G, and Baladandayuthapani, V. (2012) Hierarchical Bayesian methods for integration of various types of genomics data. IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS. https://doi.org/10.1109/GENSIPS.2012.6507713
- Gregory, K.*, Coombes, K.R.C, Momin, A, Girard, L., Byers, L., Lin, S., Peyton, M., Heymach, J., Minna, J., and Baladandayuthapani, V. (2012) Latent feature decompositions for integrative analysis of diverse high- throughput genomic data. IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS.
- Srivastava, S.*, Wang, W., Zinn, P., Colen R., and Baladandayuthapani, V.. (2012) Multi-platform genomic data using hierarchical Bayesian relevance vector machines IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS.
- Lu, C., Stewart, D.J., Lee, J.J., Ji, L., Ramesh, R., Jayachandran, G., Nunez, M.I., Wistuba, I.I., Erasmus, J.J., Hicks, M.E., Grimm, E.A., Reuben, J.M., Baladandayuthapani, V., Templeton, N.S., McMannis, J.D., and Roth, J.A. (2012) Phase I clinical trial of systemically administered TUSC2(FUS1)-nanoparticles mediating functional gene transfer in humans. PLoS One, 7(4): e34833. https://doi.org/10.1371/journal.pone.0034833
- Wang, W.*, Baladandayuthapani, V.**, Morris, J.S., Broom, B.M., Manyam, G., and Do, K.A. (2012) iBAG: integrative Bayesian analysis of high-dimensional multiplatform genomics data. Bioinformatics, 29(2): 149-159. https://doi.org/10.1093/bioinformatics/bts655
- Rawal, S., Chu, F., Zhang, M., Park, H.J., Nattamai, D., Kannan, S., Sharma, R., Delgado, D., Chou, T., Lin, H.Y., Baladandayuthapani, V... Luong, A., Vega, F., Fowler, N, Dong C., Davis, R.E. and Neelapu, S.S. (2013) Cross talk between follicular Th cells and tumor cells in human follicular lymphoma promotes immune evasion in the tumor microenvironment. Journal of Immunology, 190(12): 6681-93. https://doi.org/10.4049/jimmunol.1201363
- Ordonez, C., Garcia, J., Garcia-Alvarado, C., Cabrera, W., Baladandayuthapani, V., and Quraishi, Q. (2013) Data mining algorithms as a service in the cloud exploiting relational database systems Proc. ACM SIGMOD Conference.
- Pemmaraju, N., Tanaka, M.F., Ravandi, F., Lin, H., Baladandayuthapani, V., Rondon, G., Giralt, S.A., Chen, J., Pierce, S., Cortes, J., Kantarjian, H., Champlin, R.E., De Lima, M., and Qazilbash, M.H. (2013) Outcomes in patients with relapsed or refractory acute promyelocytic leukemia treated with or without autologous or allogeneic hematopoietic stem cell transplantation. Clinical Lymphoma, Myeloma and Leukemia 13(4):485-92. https://doi.org/10.1016/j.clml.2013.02.023
- Matusevich, D.*, Ordonez, C., and Baladandayuthapani, V.. (2013) A fast convergence clustering algorithm merging MCMC and EM methods. Proc. ACM CIKM Conference.
- Cabrera, W.*, Ordonez, C., Matusevich, D. S., and Baladandayuthapani, V. (2013) Bayesian variable selection for linear regression in high dimensional microarray data. Proc. ACM DTMBIO Workshop (CIKM Conference Workshop).
- Olivares, R.*, Rao, A,, Rao, G., Morris, J. S. and Baladandayuthapani, V. (2013) Integrative analysis of multi-modal correlated imaging-genomics data in glioblastoma. IEEE Genomic Signal Processing and Statistics (GENSIPS). https://doi.org/10.1109/GENSIPS.2013.6735914
- Bhadra, A. and Baladandayuthapani, V. (2013) Integrative sparse Bayesian analysis of high-dimensional multi-platform genomic data in glioblastoma. IEEE Genomic Signal Processing and Statistics. https://doi.org/10.1109/GENSIPS.2013.6735913
- Jennings, E.M.*, Morris, J.S., Carroll, R.J., Manyam ,G.C., and Baladandayuthapani, V. (2013) Bayesian methods for expression-based integration of various types of genomics data. EURASIP Journal on Bioinformatics and Systems Biology, 2013(1): 13. https://doi.org/10.1186/1687-4153-2013-13
- Srivastava, S.*, Wang, W., Manyam, G., Ordonez, C., and Baladandayuthapani, V. (2013) Integrating multi- platform genomic data using hierarchical Bayesian relevance vector machines. EURASIP Journal on Bioinformatics and Systems Biology, 2013(1): 9. https://doi.org/10.1186/1687-4153-2013-9
- Wang, W.*, Baladandayuthapani, V.**, Holmes, C.C., and Do, K.A. (2013) Integrative network-based Bayesian analysis of diverse genomics data. BMC Bioinformatics, 14 Suppl 13:S8. https://doi.org/10.1186/1471-2105-14-s13-s8
- Phillip, C.J., Zaman, S., Shentu, S., Balakrishnan, K., Zhang, J., Baladandayuthapani, V., Taverna, P., Redkar, S., Wang, M., Stellrecht, C.M., and Gandhi, V. (2013) Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines. Journal of Hematology and Oncology, Dec 10, 6:92. https://doi.org/10.1186/1756-8722-6-92
- Talluri, R.*, Baladandayuthapani, V., and Mallick, B.K. (2014) Bayesian sparse graphical models and their mixtures. STAT, 3(1): 109-125. https://doi.org/10.1002/sta4.49
- Bailey, A.M., Zhan, L., Maru, D., Shureiqi, I., Pickering, C.R., Kiriakova, G., Izzo, J., He, N., Wei, C., Baladandayuthapani, V., Liang, H., Kopetz, S., Powis, G., and Guo, G.L. (2014) FXR silencing in human colon cancer by DNA methylation and KRAS signaling. American Journal of Physiology, Gastrointestinal and Liver Physiology, 306(1): G48-58. https://doi.org/10.1152/ajpgi.00234.2013
- Westin, J.R., Chu, F., Zhang, M., Fayad, L.E., Kwak L.W., Fowler, N., Romaguera, J., Hagemeister, F., Fanale, M., Samaniego, F., Feng, L., Baladandayuthapani, V., Wang, Z., Ma, W., Gao, Y., Wallace, M., Vence, L.M., Radvanyi, L., Muzzafar, T., Rotem-Yehudar, R., Davis, R.E., and Neelapu, S.S. (2014) Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: a single group, open-label, phase 2 trial. Lancet Oncology, 15(1): 69-77. https://doi.org/10.1016/s1470-2045(13)70551-5
- Ajani, J.A., Wang, X., Song, S., Suzuki, A., Taketa, T., Sudo, K., Wadhwa, R., Hofstetter, W.L., Komaki, R., Maru, D.M., Lee, J.H., Bhutani, M.S., Weston, B., Baladandayuthapani, V., Yao, Y., Honjo, S., Scott, A.W., Skinner, H.D., Johnson, R.L., and Berry, D. (2013) ALDH-1 expression levels predict response or resistance to preoperative chemoradiation in resectable esophageal cancer patients. Molecular Oncology, 8(1): 142-9. https://doi.org/10.1016/j.molonc.2013.10.007
- Bjorklund C.C., Baladandayuthapani, V., Lin, H.Y., Jones, R.J., Kuiatse, I., Wang, H., Yang, J., Shah, J.J., Thomas, S.K., Wang, M., Weber, D.M., and Orlowski, R.Z. (2013) Evidence of a role for CD44 and cell adhesion in mediating resistance to lenalidomide in multiple myeloma: therapeutic implications. Leukemia, 28: 373-383. https://doi.org/10.1038/leu.2013.174
- Zhang, L.*, Baladandayuthapani, V.**, Mallick, B. K., Thompson, P. A., Bond, M. L., and Do, K. A. (2014) Bayesian hierarchical structured variable selection methods with application to MIP studies in breast cancer. Journal of Royal Statistical Society, Series C, 63(4): 595-620. https://doi.org/10.1111/rssc.12053 [Winner of SBSS best student paper award]
- Gregory, K.*, Coombes, K.R.C, Momin, A. and Baladandayuthapani, V.(2014) Latent feature decompositions for integrative analysis of diverse high-throughput genomic data. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 11(6):984-94. https://doi.org/10.1109/GENSIPS.2012.6507746
- El-Mabhouh, A.A., Ayres, M.L., Shpall, E.J., Baladandayuthapani, V., Keating, M.J., Wierda,W.G., Gandhi, V. (2014) Evaluation of bendamustine in combination with fludarabine in primary chronic lymphocytic leukemia cells. Blood, 123(23): 3780-9. https://doi.org/10.1182/blood-2013-12-541433
- Pemmaraju, N., Shah, D., Kantarjian, H., Orlowski R.Z., Nogueras Gonzlez G.M., Baladandayuthapani, V., Jain, N., Wagner, V., Garcia-Manero, G., Shah, J., Ravandi, F., Pierce, S., Takahashi, K., Daver. N., Nazha, A., Verstovsek, S., Jabbour, E., De Lima, M., Champlin, R., Cortes, J. and Qazilbash, M.H. (2014) Characteristics and outcomes of patients with multiple myeloma who develop therapy-related myelodysplastic syndrome, chronic myelomonocytic leukemia, or acute myeloid leukemia. Clinical Lymphoma, Myeloma and Leukemia, 15(2): 110-4. https://doi.org/10.1016/j.clml.2014.07.001
- Wu, W., Merriman, K., Nabaah, A., Seval, N., Seval, D., Lin, H., Wang, M., Qazilbash, M.H., Baladandayuthapani, V., Berry, D., Orlowski, R.Z., Lee, M.H. and Yeung, S.C. (2014) The association of diabetes and anti-diabetic medications with clinical outcomes in multiple myeloma. British Journal of Cancer, 111(3): 628-36. https://doi.org/10.1038/bjc.2014.307
- Nute, J.L., Le Roux, L., Chandler, A.G., Baladandayuthapani, V., Schellingerhout, D., and Cody, D.D. (2014) Differentiation of low-attenuation intracranial hemorrhage and calcification using dual-energy computed tomography in a phantom system. Investigative Radiology, 50(1): 9-16. https://doi.org/10.1097/rli.0000000000000089
- Fowler, N.H., Davis, R.E., Rawal, S., Nastoupil, L., Hagemeister, F.B., McLaughlin, P., Kwak, L.W., Romaguera, J.E., Fanale, M.A., Fayad, L.E., Westin, J.R., Shah, J., Orlowski, R.Z., Wang, M., Turturro, F., Oki, Y., Claret, L.C., Feng, L., Baladandayuthapani, V., Muzzafar, T., Tsai, K.Y., Samaniego, F., and Neelapu, S.S. (2014). Safety and activity of lenalidomide and rituximab in untreated indolent lymphoma: an open-label, phase 2 trial. Lancet Oncology, 15(12): 1311-8. https://doi.org/10.1016/s1470-2045(14)70455-3
- Voo, K.S., Foglietta, M., Percivalle, E., Chu, F., Nattamai, D., Harline, M., Lee, S.T., Bover, L., Lin, H.Y., Baladandayuthapani, V., Delgado, D., Luong, A., Davis, R.E., Kwak, L.W., Liu, Y.J., and Neelapu, S.S. (2014) Selective targeting of Toll-like receptors and OX40 inhibit regulatory T-cell function in follicular lymphoma. International Journal of Cancer, 135(12): 2834-46. https://doi.org/10.1002/ijc.28937
- Guha S., Ji, Y., and Baladandayuthapani, V. (2014) Bayesian disease classification using copy number data.
Cancer Informatics, 13(Suppl 2): 83-91. https://doi.org/10.4137/cin.s13785
- Ni, Y.*, Stingo, F.C., and Baladandayuthapani, V. (2014) Integrative Bayesian network analysis of genomic data. Cancer Informatics, 13 (Suppl 2): 39-48. https://doi.org/10.4137/cin.s13786
- Gregory, K.B., Carroll, R.J., Baladandayuthapani, V., and Lahiri, S. (2014) A two-sample test for equality of means in high dimension. Journal of the American Statistical Association Theory and Methods, 110(510): 837-849. https://doi.org/10.1080/01621459.2014.934826
- Zhang, L.*, Morris, J.S., Zhang, J., Orlowski, R. and Baladandayuthapani, V. (2014) Bayesian joint selection of genes and pathways: applications in multiple myeloma genomics. Cancer Informatics, 13(Suppl 2): 113-23. https://doi.org/10.4137/cin.s13787
- Kuiatse, I., Baladandayuthapani, V., Lin, H.Y., Thomas, S.K., Bjorklund, C.C., Weber, D.M., Wang, M., Shah, J.J., Zhang, X., Jones, R.J., Ansell, S.M., Yang, G., Treon, S.P., and Orlowski, R.Z. (2015) Targeting the spleen tyrosine kinase with fostamatinib as a strategy against Waldenstroms macroglobulinemia. Clinical Cancer Research, 21(11): 2538-45. https://doi.org/10.1158/1078-0432.ccr-14-1462
- Baladandayuthapani, V., Talluri, R., Ji, Y., Coombes, K., Hennessy, B., Davies, M., and Mallick B. K. (2015) Bayesian sparse graphical models for classification with application to protein expression data. Annals of Applied Statistics, 8(3): 1443-1468. https://doi.org/10.1214/14-aoas722
- Ordonez, C., Garcia-Alvarado, C., and Baladandayuthapani, V. (2015) Bayesian variable selection in linear regression in one pass for large data sets. ACM Transactions on Knowledge Discovery from Data (TKDD), 9(1): 1-14.
- Ha, M.J.*, Baladandayuthapani, V. and Do, K.A. (2015) Prognostic gene signature identification using causal structural learning: applications in kidney cancer. Cancer Informatics, 14 (Suppl 1): 23-35. https://doi.org/10.4137/cin.s14873
- Ni, Y.*, Stingo, S. and Baladandayuthapani, V. (2015) Bayesian non-linear directed acyclic graphical models for gene regulatory networks. Biometrics, 71(3): 585-595. [Winner of Laplace award for best Bayesian paper, JSM 2014]
- Nieto-Barajas, L.E., Ji, Y., and Baladandayuthapani, V. (2016) A semiparametric Bayesian model for comparing DNA copy numbers. Brazilian Journal of Probability and Statistics, 30(3): 345-365. http://doi.org/10.1214/15-BJPS283
- Ha, M.J.*, Baladandayuthapani, V.** and Do, K.A. (2015) DINGO: Differential Network Analysis in Genomics. Bioinformatics, 31(21): 3413-20. https://doi.org/10.1093/bioinformatics/btv406
- Wait, J.M., Cody, D., Jones, A.K., Rong, J., Baladandayuthapani, V., and Kappadath, S.C. (2015) Performance evaluation of material decomposition with rapid-kilovoltage-switching dual-energy CT and implications for assessing bone mineral density. American Journal of Roentgenology, 204(6):1234-41. https://doi.org/10.2214/ajr.14.13093
- Zhang, S., Lu, Z., Mao, W., Ahmed, A.A., Yang, H., Zhou, J., Jennings, N., Rodriguez-Aguayo, C., Lopez-Berestein, G., Miranda, R., Qiao, W., Baladandayuthapani, V,, Li, Z., Sood, A.K., Liu, J., Le, X.F., and Bast, R.C., (2015) CDK5 regulates paclitaxel sensitivity in ovarian cancer cells by modulating AKT activation, p21Cip1- and p27Kip1-mediated G1 cell cycle arrest and apoptosis. PLoS One, 10(7): e0131833. https://doi.org/10.1371/journal.pone.0131833
- Dai, B., Yan, S., Lara-Guerra, H., Kawashima, H., Sakai, R., Jayachandran, G., Majidi, M., Mehran, R., Wang, J., Bekele, B.N., Baladandayuthapani, V., Yoo, S.Y., Wang, Y., Ying, J., Meng, F., Ji, L., and Roth, J.A. (2015) Exogenous restoration of TUSC2 expression induces responsiveness to erlotinib in wildtype epidermal growth factor receptor (EGFR) lung cancer cells through context specific pathways resulting in enhanced therapeutic efficacy. PLoS One, 10(6): e0123967. https://doi.org/10.1371/journal.pone.0123967
- Sathyan, P., Zinn, P., Marisetty, A., Liu, B,, Kamal, M, Singh, S., Bady, P., Baladandayuthapani. V., and Hegi,, M., and Majumder, S. (2015) Mir-21-sox2 axis delineates glioblastoma subtypes with prognostic impact. Journal of Neuroscience, 35(45): 15097-112. https://doi.org/10.1523/jneurosci.1265-15.2015
- Azadeh, S.*, Hobbs, B., Moeller, F., Nielsen, D., and Baladandayuthapani, V.**. (2015) Integrative Bayesian analysis of neuroimaging-genetic data with application to cocaine dependence. Neuroimage,,125: 813-824. https://doi.org/10.1016/j.neuroimage.2015.10.033
- Roszik, J., Haydu, L., Joon, A., Siroy, A.E., Stingo, F.C., Baladandayuthapani, V., Hess, K.R., Tetzlaff, M., Wargo, J., Chen, K., Forget, M., Haymaker, C.L., Chen, J.Q., Meric-Bernstam, F., Eterovic, A.K., Mills Shaw, K., Mills, G., Gershenwald, J., Hwu, P., Futreal, A.P., Bernatchez, C., Radvanyi, L.G., Lazar, A., Davies, M.A. and Woodman, S.E. (2015). A novel algorithm determines tumor mutation load and predicts immune-therapy clinical outcome using a small set of gene mutations. BMC Medicine, 14(1):168. https://doi.org/10.1186/s12916-016-0705-4
- Azadeh, S.*, Hobbs, B., Moeller, F., Nielsen, D., and Baladandayuthapani, V. (2016) Integrative Bayesian analysis of neuroimaging-genetic data through hierarchical dimension reduction. IEEE International Symposium on Biomedical Imaging, 2016: 824-828. https://doi.org/10.1109/isbi.2016.7493393
- Zhang, X., Baladandayuthapani, V., Lin, H., Mulligan, G., Barlogie, B., Davis, R. E., Ma. W. C., Wang, Z., Yang, L., and Orlowski, R. Z. (2016) Tight junction protein 1 modulates proteasome capacity and proteasome inhibitor sensitivity in multiple myeloma through EGFR/JAK1/STAT3 signaling. Cancer Cell, 29(5): 639-652. https://doi.org/10.1016/j.ccell.2016.03.026
- Wang, H., Baladandayuthapani, V., Wang Z., Lin, H., Berkova, Z., Davis R. E., Yang, L. and Orlowski R. Z. (2016) Truncated protein tyrosine phosphatase receptor type O suppresses AKT signaling through IQ motif containing GTPase activating protein 1 and confers sensitivity to bortezomib in multiple myeloma. British Journal of Hematology, 8(69): 113858-11387. https://doi.org/10.18632/oncotarget.23017
- Lee, H.C., Wang, H., Baladandayuthapani, V., Lin, H., He, J., Jones, R. J., Kuiatse, I., Gu, D., Wang, Z., Brien, S. O., Keats, J., Yang, J., Davis,R. E., and Orlowski, R. Z. (2016) RNA polymerase I inhibition with CX-5461 as a novel therapeutic strategy to target c-MYC in multiple myeloma. British Journal of Hematology, 177(1): 80-94. https://doi.org/10.1111/bjh.14525
- Zoh, R, Mallick, B, K, Ivanov, I, Baladandayuthapani, V, Manyam, G., Chapkin, R., Lampe, J., and Carroll, R. J. (2016) PCAN: Probabilistic correlation analysis of two non-normal data sets. Biometrics, 72(4): 1348-1368. https://doi.org/10.1111/biom.12516
- Kim, S.*, Baladandayuthapani, V., and Lee, J. J. (2016) Prediction oriented marker selection (PROMISE)
with application to high dimensional regression. Statistics in Biosciences, 9(1): 217-245. https://doi.org/10.1007/s12561-016-9169-5
- Saha, A.*, Banerjee, S., Narang, S., Rao, G., Martinez, J., Rao, A.U.K., and Baladandayuthapani, V. (2016) DEMARCATE: Density-based magnetic resonance image clustering for assessing tumor heterogeneity in cancer. Neuroimage: Clinical, 12: 132-43. https://doi.org/10.1016/j.nicl.2016.05.012
- Mikell, J.K., Mahvash, A., Siman, W., Baladandayuthapani, V., Mourtada, F., and Kappadath, S.C. Selective internal radiation therapy with yttrium-90 glass microspheres: biases and uncertainties in absorbed dose calculations between clinical dosimetry models (2016). International Journal of Radiation Oncology, Biology and Physics, 96(4): 888-896. https://doi.org/10.1016/j.ijrobp.2016.07.021
- Xiaobo, C., Majidi, M., Feng, M., Shao, R., Wang, J., Zhao, Y., Baladandayuthapani, V., Song, J., Fang, B., Ji, L., Mehran, R., and Roth. J.A. (2016) TUSC2(FUS1)-erlotinib induced vulnerabilities in epidermal growth factor receptor(EGFR) wildtype non-small cell lung cancer(NSCLC) targeted by the repurposed drug auranofin. Scientific Reports, 15(6): 35741. https://doi.org/10.1038/srep35741
- Noren, D., Long, B., Norel, R., Rhissorrakrai, K., Hess, K., Hu, C., Bisberg, A., Schultz, ., Engquist, A., Liu, L., Lin, X., Chen, G., and Xie, H., Hunter, G., Boutros, P., Stepanov, O., DREAM 9 AML-OPC Consortium (includes Baladandayuthapani, V.. ), Norman, T., Friend, S., Stolovitzky, G., Kornblau, S., and Qutub, A. A. (2016) A crowdsourcing approach to developing and assessing prediction algorithms for AML prognosis. PLOS Computational Biology, 12(6): e1004890. https://doi.org/10.1371/journal.pcbi.1004890
- Guha, S. and Baladandayuthapani, V. (2016) Nonparametric variable selection, clustering and prediction for high-dimensional regression. Electronic Journal of Statistics, (10) 3374-3424. https://doi.org/10.48550/arXiv.1407.5472
- Zhang, L.*, Baladandayuthapani, V., Zhu, H., Baggerly, K. A., Majewski, T., Czerniak, B. A., and Morris, J. S. (2016) Functional CAR models for large spatially correlated functional datasets. Journal of the American Statistical Association – Theory and Methods, 111(514) 772-786. https://doi.org/10.1080/01621459.2015.1042581
- Bock, F., Lu, G., Srour, S.A., Gaballa, S., Lin, H.Y., Baladandayuthapani, V., Honhar, M., Stich, M., Shah, N.D., Bashir, Q., Patel, K., Popat, U., Hosing, C., Korbling, M., Delgado, R., Rondon, G., Shah, J.J., Thomas, S.K., Manasanch, E.E., Isermann, B., Orlowski, R.Z., Champlin, R.E., and Qazilbash, M.H. (2016) Outcome of patients with multiple myeloma and CKS1B gene amplification after autologous hematopoietic stem cell transplantation. Biology of Blood and Marrow Transplantation, 22(12): 2159-2164. https://doi.org/10.1016/j.bbmt.2016.09.003
- Baljevic, M, Baladandayuthapani. V Lin, H.Y, Partovi, C.M, Berkova,, Zaman, S, and Gandhi, V. V. and Orlowski, R.Z, (2017) Phase II study of the c-MET inhibitor ARQ 197 (Tivantinib) in patients with relapsed or relapsed/refractory multiple myeloma. Annals of Hematology, 96(6): 977-985. https://doi.org/10.1007/s00277-017-2980-3
- Lin, J.S., Fuentes, D., Chandler, A., Prabhu,, S., Weinberg., J., Baladandayuthapani. V ., Hazle, JD, and Schellingerhout, D. (2017) Performance assessment for brain magnetic resonance imaging registration methods. Investigative Radiology, 38(5) 973-980. https://doi.org/10.3174/ajnr.a5122
- Gentile, E., Xiaobo, C., Majidi, M., Feng, M., Shao, R., Wang, J., Zhao, Y., Baladandayuthapani. V., Song. J., Fang, B., Mehran, R., Roth, J.A., and Ji, L. (2017) Cationic liquid crystalline nanoparticles for the delivery of synthetic RNAi-based therapeutics. Oncotarget, 8(29):48222-4823. https://doi.org/10.18632/oncotarget.18421
- Wadhwa, R., Wang, X., Baladandayuthapani, V., Liu, B., Shiozaki, H., Shimodaira, Y., Lin, Q., Elimova, E., Hofstetter, W.L., Swisher, S.G., Rice, D.C., Maru, D.M., Kalhor, N., …., Berry, D., Song, S., and Ajani, J.A. (2017) Nuclear expression of Gli-1 is predictive of pathologic complete response to chemoradiation in trimodality treated oesophageal cancer patients. British Journal of Cancer, 117(5): 648-655. https://doi.org/10.1038/bjc.2017.225
- Zhang, Y., Linder, M., Shojaie, A., Ouyang, Z., Shen, R., Baggerly, K. A., Baladandayuthapani, V., and Zhao H. (2017) Dissecting pathway disturbances using network topology and multi-platform genomics data. Statistics in Biosciences, (10): 86-106. http://dx.doi.org/10.1007/s12561-017-9193-0
- Yu, K., Zhang, Y., Yuc, Y., Huang, C., Liu, R., Li, T., Yang, T., Morris, J.S., Baladandayuthapani, V.,
and Zhu, H. (2017) Radiomic analysis in prediction of human papilloma virus status. Clinical and Translational Radiation Oncology, (7): 49-54. https://doi.org/10.1016/j.ctro.2017.10.001
- Ye, X., Wang, R., Bhattacharya, R., Boulbes, D., Fan, F., Xia, L., Adoni, H., Ajami, N., Wong, M., Smith, D., Petrosino, J., Venable, S., Qiao, W., Baladandayuthapani. V., Maru, D., and Ellis, L.M. (2017) Fusobacterium nucleatum subspecies animalis influences pro-inflammatory cytokine expression and monocyte activation in human colorectal tumors. Cancer Prevention Research, 10(7): 398-409. https://doi.org/10.1158/1940-6207.capr-16-0178
- Morris, J. S., and Baladandayuthapani, V. (2017) Statistical modeling, structured learning, and integration in bioinformatics. Statistical Modeling, 17(4-5): 245-289. https://doi.org/10.1177/1471082x17698255 Discussion Paper with Rejoinder
- Ni, Y.*, Stingo, S., and Baladandayuthapani, V. Sparse multi-dimensional graphical models: a Bayesian unified framework. (2017) Journal of the American Statistical Association – Theory & Methods, 112(518): 779-793. https://doi.org/10.1080/01621459.2016.1167694
- Zhu, B., Song, N., Shen, R., Arora, A., Machiela M., Song, L., Landi, M., Ghosh, D., Chatterjee, N., Baladandayuthapani, V., and Zhao, H. (2017) Integrating clinical and multiple omics data for prognostic assessment across human cancers. Scientific Reports, 7(1): 16954. https://doi.org/10.1038/s41598-017-17031-8
- Bharath K, Kambadur, P., Dey D., Rao. A, and Baladandayuthapani, V.. Statistical tests for large tree-structured data (2017). Journal of the American Statistical Association – Theory & Methods, 112(520): 1733-1743. https://doi.org/10.1080/01621459.2016.1240081
- Shoemaker, K., Hobbs, B.P., Bharath, K., Ng, C.S., and Baladandayuthapani, V. (2018) Tree-based methods for characterizing tumor density heterogeneity. Pacific Symposium of Biocomputing, 23: 216-227.
- Class, C.A, Ha, M.J., Baladandayuthapani, V., and Do, K.A. (2018) iDINGO - Integrative differential network analysis in genomics with shiny application. Bioinformatics, 34(7): 1243-1245. https://doi.org/10.1093/bioinformatics/btx750
- Kundu, S.*, Cheng, Y., Shin, M., Manyam G., Mallick, B., and Baladandayuthapani, V. (2018) Bayesian variable selection with structure learning: applications in integrative genomics. Plos One, 13(7). https://doi.org/10.1371/journal.pone.0195070
- Bhadra, A., Rao A., and Baladandayuthapani, V. (2018) Inferring network structure in non-normal and mixed discrete-continuous genomic data. Biometrics, 74(1): 185-195. https://doi.org/10.1111/biom.12711
- Lee, W., Miranda, M., Rauch, P., Baladandayuthapani, V., Fazio, M., Downs, C., and Morris, J. S. (2018) Semipara- metric functional mixed models for longitudinal functional data with application to glaucoma data. Journal of the American Statistical Association – Applications & Case Studies, 114(526): 495-513. https://doi.org/10.1080/01621459.2018.1476242
- Kappadath, S. C., Mikell, J., Balagopal, A., Baladandayuthapani, V., and Mahvash, A. (2018). Hepato- cellular carcinoma tumor dose response after 90Y-radioembolization with glass microspheres using 90Y-SPECT/CT-based voxel dosimetry. International Journal of Radiation Oncology Biology Physics, 102(2): 451-461. https://doi.org/10.1016/j.ijrobp.2018.05.062
- Zhang, X., Lee, H. C., Shirazi, F., Baladandayuthapani, V., and Orlowski, R. Z. (2018). Protein targeting chimeric molecules specific for bromodomain and extra-terminal motif family proteins are active against pre-clinical models of multiple myeloma. Leukemia, 32:2224-2. https://doi.org/10.1038/s41375-018-0044-x
- Ruder, D., Papadimitrakopoulou, V., Shien, K., Behrens, C., Baladandayuthapani, V., and Izzo, J. G. (2018). Concomitant targeting of the mTOR/MAPK pathways: novel therapeutic strategy in subsets of RICTOR/KRAS-altered non-small cell lung cancer. Oncotarget, 9(74): 33995-34008. https://doi.org/10.18632/oncotarget.26129
- Zinn, P. O., Singh, S. K., Kotrotsou, A., Hassan, I., Baladandayuthapani, V., and Colen, R. R. (2018). 100 toward the co-clinical glioblastoma treatment paradigm radiomic machine learning identifies glioblastoma gene expression in patients and corresponding xenograft tumor models. Neurosurgery, 65(Suppl 1): 80. https://doi.org/10.1093/neuros/nyy303.100
- Elhalawani, H., Lin, T. A., Volpe, S., Mohamed, A.S.R., White, A.L., Zafereo, J., Wong, A.J., Berends, J.E., AboHashem, S., Williams, B., Aymard, J.M., … Zhang, Y., Zhu, H., Morris, J.S., Baladandayuthapani, V., Shumway, J.W., Ghosh, A., Pohlman, A., Phoulady, H.A., Goyal, V., Canahuate, G., Marai, G.E., Vock, D., Lai, S.Y., Mackin, D.S., Court, L.E., Freymann, J., Farahani, K., Kaplathy-Cramer, J., and Fuller, C. D. (2018). Machine learning applications in head and neck radiation oncology: lessons from open-source radiomics challenges. Frontiers in Oncology, 8:294. https://doi.org/10.3389/fonc.2018.00294
- Meraz, I. M., Majidi, M., Cao, X., Lin, H., Baladandayuthapani, V., and Roth, J. A. (2018). TUSC2 immunogene therapy synergizes with anti-PD-1 through enhanced proliferation and infiltration of natural killer cells in syngeneic kras-mutant mouse lung cancer models. Cancer Immunology Research, 6(2): 163-177. https://doi.org/10.1158/2326-6066.cir-17-0273
- Davenport, C. A., Maity, A., and Baladandayuthapani, V. (2018). Functional interaction–based nonlinear models with application to multiplatform genomics data. Statistics in Medicine, 37(18): 2715-2733. https://doi.org/10.1002/sim.7671
- Ni, Y.*, Stingo, S. and Baladandayuthapani, V. (2018) Bayesian graphical regression. Journal of the American Statistical Association – Theory & Methods, 114(525): 184-197. https://doi.org/10.1080/01621459.2017.1389739
- Ha, M., Banerjee, S., Akbani, R., Liang, H., Mills, G., Do, K.A., and Baladandayuthapani, V. (2018) Personalized integrated network modeling of the cancer proteome atlas. Nature Scientific Reports, 8(1): 14924. https://doi.org/10.1038/s41598-018-32682-x
- Zinn, P. O., Singh, S., Kotrotsou, A., Hassan, I., Baladandayuthapani, V., and Colen, R. R. (2018). A coclinical radiogenomic validation study: conserved magnetic resonance radiomic appearance of periostin-expressing glioblastoma in patients and xenograft models. Clinical cancer research: an official journal of the American Association for Cancer Research, 24(24): 6288-6299. https://doi.org/10.1158/1078-0432.ccr-17-3420
- Ni, H., Shirazi, F., Baladandayuthapani, V., Lin, H., and Orlowski, R. Z. (2018). Targeting myddosome signaling in Waldenstrom’s macroglobulinemia with the interleukin-1 receptor- associated kinase 1/4 inhibitor R191. Clinical cancer research: an official journal of the American Association for Cancer Research, 24(24): 6408-6420. https://doi.org/10.1158/1078-0432.ccr-17-3265
- Bharath, K., Kurtek, S., Rao, A., and Baladandayuthapani, V. (2018). Radiologic image-based statistical shape analysis of brain tumours. Journal of the Royal Statistical Society. Series C: Applied Statistics, 67(5): 1357-1378. https://doi.org/10.1111/rssc.12272
- Kundu, S.*, Baladandayuthapani, V., and Mallick, B. K. (2019) Bayes regularized graphical model estimation in high dimensions, Bayesian Analyses, arXiv preprint arXiv:1308.3915. https://doi.org/10.1093/biostatistics/kxj008
- Marisetty, A. L., Lu, L., Veo, B. L., Liu, B, Baladandayuthapani, V., and Majumder, S. (2019). REST-DRD2 mechanism impacts glioblastoma stem cell-mediated tumorigenesis. Neuro-oncology, 21(6): 775-785. https://doi.org/10.1093/neuonc/noz030
- Ye, J. C., Chen, L., Chen, J., Parkin, B., Polk, A., Kandarpa, M., Cole, C. E., Campagnaro, E. L., Robinson, D., Wu, Y.-M., Talpaz M., Yesil J., Leif, P., Chinnaiyan, A., Baladandayuthapani V. (2019) Aneuploidy is associated with inferior survival in relapsed refractory multiple myeloma patients. Blood, 134(1):4360. https://doi.org/10.1182/blood-2019-124135
- Banerjee, S.*, Akbani, R., and Baladandayuthapani, V. (2019). Spectral clustering via sparse graph structure learning with application to proteomic signaling networks in cancer. Computational Statistics and Data Analysis, 132:46-69. https://doi.org/10.1016/j.csda.2018.08.009
- Gates, E.D.H., Lin, J. S., Weinberg, J. S., Hamilton, J., Baladandayuthapani, V., and Schellingerhout,
D. (2019). Guiding the first biopsy in glioma patients using estimated Ki-67 maps derived from MRI:
conventional versus advanced imaging. Neuro-oncology, 21(4): 527-536. https://doi.org/10.1093/neuonc/noz004
- Ni, Y.*, Stingo, S., and Baladandayuthapani, V. Bayesian hierarchical varying-sparsity model with application to cancer proteogenomics. (2019) Journal of American Statistical Association – Applications & Case Studies, 114(525): 48-60. https://doi.org/10.1080/01621459.2018.1434529
- Manasanch,E.E., Han, G., Mathur, R., Qing, Y., Zhang, Z., Lee, H., Weber, D.M., Amini, B., Berkova, Z., Eterovic, K., Zhang, S., Zhang, J., Song, X., Mao, X., Morgan, M., Feng, L., Baladandayuthapani, V., Futreal, A., Wang, L., Neelapu, S.S., and Orlowski, R.Z. (2019). A pilot study of pembrolizumab in smoldering myeloma: report of the clinical, immune, and genomic analysis. Blood Advances, 3(18): 2712. https://doi.org/10.1182/bloodadvances.2019000881
- Gates, E.D.H., Lin, J.S., Weinberg, J.S., Prabhu, S.S., Hamilton, J., Hazle, J.D., Fuller, G.N., Baladandayuthapani, V., Fuentes, D.T., and Schellingerhout, D. (2020). Imaging-based algorithm for the local grading of glioma. American Journal of Neuroradiology, 41(3): 400-407. https://doi.org/10.3174/ajnr.a6405
- Reuben, A., Zhang, J., Chiou, S.H., Gittelman, R.M., Li, J., Lee, W.C., Fujimoto, J., Behrens, C., Liu, X., Wang, F., Quek, K., Wang, C., Kheradmand, F., Chen, R., Chow, C.W., Lin, H., Bernatchez, C., Jalali, A., Hu, X., Wu, C.J., Eterovic, A.K., Parra, E.R., Yusko, E., Emerson, R., Benzeno, S., Vignali, M., Wu, X., Ye, Y., Little, L.D., Gumbs, C., Mao, X., Song, X., Tippen, S., Thornton, R.L., Cascone, T., Snyder, A., Wargo, J.A., Herbst, R., Swisher, S., Kadara, H., Moran, C., Kalhor, N., Zhang, J., Scheet, P., Vaporviyan, A.A., Sepesi, B., Gibbons, D.L., Robins, H., Hwu, P., Heymach, J.V., Sharma, P., Allison, J.P., Baladandayuthapani, V., Lee, J.J., Davis, M.M., Wistuba. I.I., Futreal, P.A., and Zhang, J. (2020). Comprehensive T cell repertoire characterization of non-small cell lung cancer. Nature Communications, 11(1):603. https://doi.org/10.1038/s41467-019-14273-0
- Maity, A.K.*, Bhattacharya, A., Mallick, B., and Baladandayuthapani, V (2020). Bayesian data integration and variable selection for pan-cancer survival prediction using protein expression data. Biometrics, 76(1): 316-325. https://doi.org/10.1111/biom.13132
- Yang, H*, Baladandayuthapani. V, Rao. A. and Morris, J.S (2020). Quantile Function on Scalar Regression Analysis for Distributional Data. Journal of American Statistical Association – Applications & Case Studies. 115 (529): 90-106. https://doi.org/10.1080/01621459.2019.1609969
- Liu, Q.*, Ha, M. J., Bhattacharya, R., Garmire, L., and Baladandayuthapani, V (2020). Network-based matching of patients and targeted therapies for precision oncology. Pacific Symposium of Biocomputing 25:623-634
- Guha, N., Baladandayuthapani, V. and Mallick, B. K. (2020). Quantile graphical models: Bayesian approaches. Journal of Machine Learning Research 21(79):1−47, 2020.
- Das, P.*, Peterson, C., Do, K., Akbani, R. and Baladandayuthapani, V. (2020) NExUS: Bayesian simultaneous network estimation across unequal sample sizes. Bioinformatics, 3 (36), 798-804. https://doi.org/10.1093/bioinformatics/btz636
- Zhang, Y.*, Morris, J. S., Rao, A., and Baladandayuthapani, V. (2020) Radio-iBAG: Radiogenomics - integrative Bayesian analysis of high dimensional multiplatform genomics data. Annals of Applied Statistics, 3(13), 1957-1988. [link]
- Ha, M. J.*, Stingo F. C., and Baladandayuthapani, V. (2020) Bayesian structure learning in multilayered genomic networks. Journal of American Statistical Association – Applications & Case Studies, https://doi.org/10.1080/01621459.2020.1775611
- Bhattacharyya, R., Ha, M. J., Liu, Q., Akbani, R., Liang, H., Baladandayuthapani, V. (2020) Personalized network modeling of the pan-cancer patient and cell line interactome. Journal of Clinical Oncology - Clinical Cancer Informatics, 4, 399-411. https://doi.org/10.1200/cci.19.00140
- Ray D., Salvatore M., Bhattacharyya R., Wang L., Du J., Mohammed S., Purkayastha S., Halder A., Rix A., Barker D., Kleinsasser M., Zhou Y., Bose D., Song P., Banerjee M., Baladandayuthapani V., Ghosh P., Mukherjee B. (2020) Predictions, role of interventions and effects of a historic national lockdown in India's response to the COVID-19 pandemic: data science call to arms. Harvard Data Science Review. https://doi.org/10.1200/cci.19.00140
- Gates E. D. H., Weinberg J. S., Prabhu S. S, Lin J. S., Hamilton J., Hazle J. D., Fuller G. N., Baladandayuthapani V., Fuentes D. T., Schellingerhout D. (2021) Estimating local cellular density in glioma using MR imaging data. American Journal of Neuroradiology, 42(1):102-108. https://doi.org/10.3174/ajnr.a6884
- Tanaka I, Dayde D, Tai MC, Mori H, Solis LM, Tripathi SC, Fahrmann JF, Unver N, Parhy G, Jain R, Parra ER, Murakami Y, Aguilar-Bonavides C, Mino B, Celiktas M, Dhillon D, Casabar JP, Nakatochi M, Stingo F, Baladandayuthapani V, Wang H, Katayama H, Dennison JB, Lorenzi PL, Do KA, Fujimoto J, Behrens C, Ostrin EJ, Rodriguez-Canales J, Hase T, Fukui T, Kajino T, Kato S, Yatabe Y, Hosoda W, Kawaguchi K, Yokoi K, Chen-Yoshikawa TF, Hasegawa Y, Gazdar AF, Wistuba II, Hanash S, Taguchi A (2022) SRGN-triggered aggressive and immunosuppressive phenotype in a subset of TTF-1-negative lung adenocarcinomas. Journal of National Cancer Institute. https://doi.org/10.1093/jnci/djab183
- Qazilbash MH, Saini NY, Soung-Chul C, Wang Z, Stadtmauer E, Baladandayuthapani V, Lin H, Tross B, Honhar M, Rao SS, Kim K, Popescu M, Szymura SJ, Zhang T, Anderson AJ, Bashir Q, Shpall EJ, Orlowski RZ, Levine BL, Kerr N, Garfall A, Cohen AD, Vogl DT, Dengel K, June CH, Champlin RE, Kwak LW (2022). A randomized phase II trial of idiotype vaccination and adoptive autologous t-cell transfer in multiple myeloma patients. Blood. https://doi.org/10.1182/blood.2020008493
- Mohammed, S.*, Bharath, K., Kurtek, S, Rao, A, and Baladandayuthapani, V. (2021) RADIOHEAD: radiogenomic analysis incorporating tumor heterogeneity in imaging through densities. Annals of Applied Statistics.
- Wang, Z., Baladandayuthapani, V, Kaseb, A., Hassan, M. M., Wang, W., Morris J. S. (2022) Bayesian edge regression in undirected graphical models to characterize interpatient heterogeneity in cancer. JASA– Applications & Case Studies doi.org/10.1080/01621459.2021.2000866
- Saha, A.*, Ha, M., Baladandayuthapani, V. (2022). A Bayesian framework for calibrating individualized therapeutic index in pharmacogenomic studies. Annals of Applied Statistics 16(4): 2055-2082 . https://doi.org/10.1214/21-AOAS1550
- Ni, Y., Baladandayuthapani, V., Vannucci, M. and Stingo F. C. (2021). Bayesian graphical models for modern biological applications (with discussion). Statistical Methods & Applications. https://link.springer.com/article/10.1007/s10260-021-00572-8
- Ni, Y., Baladandayuthapani, V., Vannucci, M. and Stingo F. C. (2022). Rejoinder to the discussion of “Bayesian graphical models for modern biological applications” Statistical Methods & Applications. https://link.springer.com/article/10.1007/s10260-022-00634-5
- Bhattacharyya, R., Banerjee S., Mohammed S. and Baladandayuthapani, V. (2022+). Spatial network-based modeling of COVID-19 dynamics: early pandemic spread in India. Journal of Indian Statistical Association (in press)
- Das, P.**, Peterson, C., Ni. Y., Rueben. A., Zhang. J., Do, K., and Baladandayuthapani, V.(2022+) Bayesian hierarchical quantile regression with application to characterizing the immune architecture of lung cancer. Biometrics. (in press) https://doi.org/10.1111/biom.13774
- Panigrahi, S., Mohammed, S.**, Rao, A. and Baladandayuthapani, V. (2022+) Integrative Bayesian models using post-selective inference: a case study in radiogenomics. Biometrics (in press). https://doi.org/10.1111/biom.13740
- Yao, T-H*, Wu Z., Bharath, K., Li, J. and Baladandayuthapani, V. (2022+). Probabilistic learning of treatment trees in cancer. Annals of Applied Statistics. (in press)
- Acharyya, S.**, Zhou X., and Baladandayuthapani, V. (2022). SpaceX: gene co-expression network estimation for spatial transcriptomics. Bioinformatics (in press) [Winner of Early Career Paper Award from Biometrics Section of ASA, JSM 2022] https://doi.org/10.1093/bioinformatics/btac645
- Desai, N.*, Morris, J.S., and Baladandayuthapani, V. (2022). NETCELLMATCH: multiscale network-based matching of cancer cell lines to patients using graphical wavelets. Chemistry & Biodiversity https://doi.org/10.1002/cbdv.202200746
- Bhattacharyya, R.*, Burman, A., Singh, K., Banerjee, S., Maity, S., Auddy, A., Rout, S.K., Lahoti, S., Panda, R and Baladandayuthapani, V. (2022+). Role of multi-resolution vulnerability indices in COVID-19 spread: a case study in India. BMJ Open https://doi.org/10.1101/2021.07.19.21260791
- Bhattacharyya, R.*, Henderson, N., and Baladandayuthapani, V. (2022+). BaySyn: Bayesian evidence synthesis for multi-system multiomic integration. In Pacific Symposium on Biocomputing, Vol. 28, No. 2023. http://dx.doi.org/10.1136/bmjopen-2021-056292
- Ni, Y., Stingo F. C. and Baladandayuthapani, V. (2022). Bayesian covariate-dependent gaussian graphical models with varying structure. Journal of Machine Learning Research. 23(242):1−29 https://www.jmlr.org/papers/v23/21-0102.html
- Morikawa A, Li J, Ulintz P, Cheng X, Apfel A, Robinson D, Hopkins A, Kumar-Sinha C, Wu YM, Serhan H, Verbal K, Thomas D, Hayes DF, Chinnaiyan AM, Baladandayuthapani V, Heth J, Soellner MB, Merajver SD, Merrill N. (2023). Optimizing Precision Medicine for Breast Cancer Brain Metastases with Functional Drug Response Assessment. Cancer Res Commun. 2023 Jun 21;3(6):1093-1103. doi: 10.1158/2767-9764.CRC-22-0492
- Chekuo, T., Stingo, F.C., Mohammed S.*, Rao, A., and Baladandayuthapani, V. (2023). A Bayesian group selection with compositional responses for analysis of radiologic tumor proportions and their genomic determinants. Annals of Applied Statistics. 2023 Dec 17(4): 3013-3034. https://doi.org/10.1214/23-aoas1749
- Mohammed, S.*, Kurtek, S., Bharath, K., Rao, A., Baladandayuthapani, V. (2023). Tumor radio- genomics with Bayesian layered variable selection. IEEE Transactions in Medical Imaging. 2023 Dec 90(102964). https://doi.org/10.1016/j.media.2023.102964
- Osher, N.*, Kang, J., Krishnan, S., Rao, A. and Baladandayuthapani, V. (2023). SPARTIN: a Bayesian Method for the Quantification and Characterization of Cell Type Interactions in Spatial Pathology Data. Frontiers in Genetics. 2023 May 18:14:1175603. https://doi.org/10.3389/fgene.2023.1175603
- Masotti M, Osher N*, Eliason J, Rao A, Baladandayuthapani V. (2023). DIMPLE: An R-Package to Quantify, Visualize and Model spatial cellular interactions from Multiplex Imaging with Distance Matrices. Cell Patterns. 2023 Dec 4(12): 100879. https://doi.org/10.1016/j.patter.2023.100879
- Gu C., Baladandayuthapani V., and Guha S. (2023) Nonparametric Bayes Differential Analysis of Multigroup DNA Methylation Data. Bayesian Analysis DOI: 10.1214/23-BA1407
- Zakharia Y, Singer E, Acharyya S, Garje R, Joshi M, Peace D, Baladandayuthapani V, Lalancette C, Kryczek I, Zou W, Alva A (2024). Durvalumab and guadecitabine in advanced clear cell renal cell carcinoma: results from the phase Ib/II study BTCRC-GU16-04. Nature Communications. 2024 Feb 15(972). https://doi.org/10.1038/s41467-024-45216-z
- Khalatbari S, Baladandayuthapani V, Kaciroti N, Samuels E, Bugden J, Spino C. Developing a Bayesian workshop for full-time staff statisticians. J Clin Transl Sci. 2024 Jun 4;8(1):e105. doi: 10.1017/cts.2024.558. PMID: 39655005; PMCID: PMC11626572.
- Whitehead CE, Ziemke EK, Frankowski-McGregor CL, Mumby RA, Chung J, Li J, Osher N, Coker O, Baladandayuthapani V, Kopetz S, Sebolt-Leopold JS. A first-in-class selective inhibitor of EGFR and PI3K offers a single-molecule approach to targeting adaptive resistance. Nat Cancer. 2024 Aug;5(8):1250-1266. doi: 10.1038/s43018-024-00781-6. Epub 2024 Jul 11. PMID: 38992135; PMCID: PMC11357990.
- Bhattacharyya, R.*, Henderson, N., and Baladandayuthapani, V (2024). Functional Integrative Bayesian Analysis of High-dimensional Multiplatform Genomic Data. Journal of American Statistical Association (under revision) Journal of the American Statistical Association, 119(548), 2533–2547. https://doi.org/10.1080/01621459.2024.2388909
- Chakraborty, M., Baladandayuthapani, V., Bhadra, A. and Ha, M. J. (2024). Bayesian Robust Learning in Chain Graph Models for Integrative Pharmacogenomics. Annals of Applied Statistics 18, 3274–3296. [doi link]
- Choi J*, Baladandayuthapani V, and Kang J (2024) Latent spatial dirichlet allocation, NeurIPS BDU Workshop.
- Mohammed, S., Masotti, M., Osher, N., Acharyya, S., and Baladandayuthapani, V. (2024). Statistical Analysis of Quantitative Cancer Imaging Data. Statistics and Data Science in Imaging, 1(1). https://doi.org/10.1080/29979676.2024.2405348
- Yao TH*, Ni Y, Bhadra A, Kang J, Baladandayuthapani V. (2025) Robust Bayesian graphical regression models for assessing tumor heterogeneity in proteomic networks, Biometrics, In Press.
- Liu Q* , Li G., and Baladandayuthapani V (2025+). Pan-cancer drug response prediction using integrative principal component regression. Statistics in Biosciences, In Press.
- Desai, N*., Baladandayuthapani, V., Shinohara, R. T., & Morris, J. S. (2025). Covariance Assisted Multivariate Penalized Additive Regression (CoMPAdRe). Journal of Computational and Graphical Statistics, 1–10. https://doi.org/10.1080/10618600.2024.2407453
- Desai, N*, Baladandayuthapani V, Shinohara, R; Morris, J. S. (2025+) Connectivity Regression, Biostatistics, In Press
- Chen L* , Acharyya S.*, Luo C., Ni Y. and Baladandayuthapani V (2025+). GraphR: Probabilistic Graphical Modeling under Heterogeneity (accepted in Cell Reports Methods)
INVITED EDITORIALS
- Jiang, H., An, L., Baladandayuthapani, V., and Auer, P.L. Classification, predictive modelling, and statistical analysis of cancer data (a). (2014) Cancer Informatics, 13(Supple 2): 1-3.
BOOK CHAPTERS
- Baladandayuthapani, V., Ray, S., and Mallick, B. K. (2005). Bayesian Methods for DNA Microarray Data Analysis. In Rao C. R. and Dey D. K. (eds.) Handbook in Statistics Bayesian Statistics: Modeling and Computation. Elseiver: Amsterdam.
- Baladandayuthapani, V., Holmes, C. C., Mallick, B. K. and Carroll, R. J. (2006). Modeling Nonlinear Gene Interactions using Bayesian MARS. In Do K. A., Mu¨eller P. and Vannucci M. (eds.) Bayesian Inference for Gene Expression and Proteomics. Cambridge University Press.
- Rossell, D*, Baladandayuthapani. V, and Johnson, V. E. (2008). Bayes Factors Based on Test Statistics under Order Restrictions. In Hoijtink H., Klugkist I. , Boelen P (eds) Bayesian Evaluation of Informative Hypotheses in Psychology. Springer.
- Wang, W*. Baladandayuthapani. V , Holmes, C. C. and Do, K-A. (2013) Bayesian graphical models for integrating multiplatform genomics data. In: Advances in Statistical Bioinformatics: Models and Integrative Inference for High-Throughput Data.
- Baladandayuthapani. V, Wang X, Mallick BK, Do K-A. (2014). Bayesian functional mixed models for survival responses with application to prostate cancer. In: Recent Advances in Applied Statistics: Slected Papers from the 2013 ICSA Applied Statistics Symposium.
- Jennings EM*, Morris JS, Manyam G, Carroll R J., Baladandayuthapani. V (2015) Bayesian models for flexible integrative analysis of multi-platform genomics data. In: Integrating omics data: statistical and computational methods (in press)
- Ni, Y*, Marcetti, G, Baladandayuthapani. V and Stingo, F. C. (2015) Bayesian approaches for large biological networks. In Nonparametric Bayesian Inference in Biostatistics. Editors: Peter Mueller and Riten Mitra
- Guha, S, Banerjee, S*, Gu, C, and Baladandayuthapani. V. (2015) Nonparametric Variable Selection, Clustering and Prediction for Large Biological Datasets In Nonparametric Bayesian Inference in Biostatistics. Editors: Peter Mueller and Riten Mitra
SELECTED PREPRINTS
- Zhang L., Baladandayuthapani, V and Morris, J.S. Bayesian functional graphical models. Journal of American Statistical Association (under second revision)
- Sagar, K., Ni, Y., Baladandayuthapani, V. and Bhadra, A. Individualized Inference using Bayesian Quantile Directed Acyclic Graphical Models. Journal of Machine Learning Research (submitted) arXiv:2210.08096
- Yao, T.*, Wu, Z., Bharath, K., Baladandayuthapani, V.. Geometry-driven Bayesian Inference for Ultrametric Covariance Matrices. https://doi.org/10.48550/arXiv.2401.11515 (under revision in JRSS-B).
- Osher N*, Kang J., and Baladandayuthapani, V. Spatially Structured Regression for Non-conformable Spaces: Integrating Pathology Imaging and Genomics Data in Cancer (submitted to Annals of Applied Statistics)
GRANT SUPPORT (CURRENT/FUNDED)
- Principal Investigator (MPI with J. Morris), Bayesian Network-Based Integrative Genomics Methods for Precision Medicine, National Institutes of Health, R01 CA 244845, 2/1/2021-1/31/2026
- Core Director, Cancer Data Sciences Shared Resource, Cancer Center Support Grant, National Institutes of Health (PI: Eric Fearon) P30 CA 046592, 6/01/2023 - 5/31/2028
- Core Director, Data Analyses Core, Genetics and Genomics of Leiomyosarcoma (LMS): Improved Understanding of Cancer Biology and New Approaches to Diagnosis and Treatment, National Institutes of Health, PI: Laurence Baker, Scott Schuetze, P50 CA 272170, 7/2022-6/2027
- Co-Investigator, ALOX15 Regulation of Colon Cancer Invasiveness via P13P-Linoleic Acid Metabolism, National Institutes of Health (PI: Imad Shureiqi) R01 CA 266223, 9/2021-8/2026
- Co-Investigator, PARTNERSHIP: Developing a Dietary Approach in the Management of Inflammatory Bowel Disease, USDA, PI: Grace Chen, USDA-NIFA-AFRI-007692, 1/2022-12/2024
- Co-Investigator, Michigan Center for Translational Cancer Proteogenomics, National Institutes of Health, PI: Arul Chinnaiyan, Saravana Dhanasekaran, Alexey Nesvizhskii, U24 CA 271037, 4/2022-3/2027
GRANT SUPPORT (COMPLETED IN LAST 3 YEARS)
- Co-Investigator, 2018.050 IMPACT: Immunotherapy in Patients with Metastatic Cancers and CDK12 Mutations, Bristol-Myers Squibb, (PI: Ajjai Alva), CA209-8JJ, 8/2018-7/2023
- Co-Investigator, 2017.053 UM/BTCRC/AZ/Astex, Hoosier Cancer Foundation, (PI: Ajjai Alva) BTCRCGU 16043, 1/2018-1/2023
- Principal Investigator, Collaborative Research: New Bayesian Nonparametric Paradigms of Personalized Medicine for Lung Cancer, National Science Foundation, 13-570, 9/2015-8/2021
- Principal Investigator, (MPI with MJ Ha), Proteomic-based Integrated Subject-Specific Networks in Cancer, National Institutes of Health/National Cancer Institute, R21, 4/2018- 5/2021
- Principal Investigator, (MPI with Bani Mallick) Bayesian Graphical Models for Integration of Omics Data, R01 CA194391-01, National Institutes of Health/National Cancer Institute, 12/2015-11/2021
- Co-Investigator, Bayesian Methods for Complex, High Dimensional Functional Data in Cancer Research, R01 CA 178744, National Institutes of Health/National Cancer Institute, (PI: Jeffrey Morris), 9/2015-8/2020
RESEARCH ADVISING/MENTORING
- Francesco C Stingo, Associate Professor of Statistics, University of Florence
- Brian P Hobbs, Associate Professor of Biostatistics, UT MD Anderson Cancer Center
- Arvind U Rao, Assistant Professor of Bioinformatics and Computational Biology, UT MD Anderson Cancer Center (now at University of Michigan)
- Karthik Bharath, Dept of Statistics, University of Nottingham
- Anindya Bhadra, Dept. of Statistics, Purdue University
- Min Jin Ha, Assistant Professor of Biostatistics, UT MD Anderson Cancer Center
- Christine B Peterson, Assistant Professor of Biostatistics, UT MD Anderson Cancer Center
- Zhenke Wu, Assistant Professor of Biostatistics, University of Michigan
- Maria Masotti, Research Assistant Professor of Biostatistics, University of Michigan
- Nicholas Henderson, Assistant Professor of Biostatistics, University of Michigan
- David Rossell Ribera, 2006-2007, (with V. E. Johnson), Current position: Ramón y Cajal Fellow at Universitat Pompeu Fabra
- Suprateek Kundu, 2012-2014, (with B. K. Mallick), First position: Assistant Professor, Dept. of Biostatistics, Emory University; Current position: Associate Professor, Dept. of Biostatistics, UT MD Anderson Cancer Center
- Wenting Wang, 2010 - 2013 (with K-A. Do), Current position: Biostatistician, Biogen Inc.
- Lin Zhang, 2012-2015 (joint with J.S. Morris), Current position: Associate Professor, Dept. of Bio- statistics, University of Minnesota
- Bruce Bugbee, 2014 – 2015 (with Jeffrey S. Morris) Current position: Computational Statistician, Na- tional Renewable Energy Laboratory, Colorado
- Sayantan Banerjee, 2014 – 2016 Current position: Assistant Professor, Indian Institute of Management, Indore.
- Min Jin Ha, 2013 – 2016 (with K-A. Do) First position: Assistant Professor of Biostatistics, UT MD Anderson Cancer Center; Current position: Associate Professor Graduate School of Public Health, Yonsei University
- Priyam Das, 2017 – 2019 (with C. Peterson and K-A. Do), Current Position: Assistant Professor, Virginia Commonwealth University
- Hojin Yang, 2016 – 2019 (with J. S. Morris) Current Position: Assistant Professor, Pusan National University
- Abhishek Saha 2016 – 2019, Current Position: Research Fellow, National Institutes of Health
- Shariq Mohammed, 2018 – 2021 (with Arvind Rao) UM Precision Health Scholar. Current position: Assistant Professor, Boston University
- Moumita Chakraborty, 2019 – 2022 (with M. J. Ha) Current Position: Assistant Professor, The University of Texas Medical Branch, Galveston
- Satwik Acharyya, 2020 –2024. Winner of Early Career Paper Award, Biometrics Section, 2022. Current Position: Assistant Professor, University of Alabama, Birmingham.
- Junsouk Choi, 2023 – 2025 Current Position: Assistant Professor, Korea University.
- Ph.D. Students (as primary advisor/co-advisor)
- Rajesh Talluri (Ph.D. 2011) Texas A&M University (joint with Bani K. Mallick) Current position: Assistant Professor, Department of Data Science. University of Mississippi Medical Center
- Lin Zhang (Phd 2012) Texas A&M University (joint with Bani K Mallick) winner of SBSS best paper award 2012 Current position: Associate Professor, Dept. of Biostatistics, University of Minnesota
- Yang Ni (Phd 2015), Rice University (joint with Francesco Stingo) Winner of Laplace Award 2014; Boyd Harshbarger Travel Award; Jiann-Ping Hsu Pharmaceutical and Regulatory Sciences Award; Young Investigator Travel Award, G70 Conference; Current position: Associate Professor, Department of Statistics, Texas A&M Univeristy
- Shabnam Azadeh (Phd 2015) UT School of Public Health (with Brian P Hobbs) Current position: FDA; Selected for RSNA Oral Presentation
- Elizabeth Jennings (PhD, 2015) Texas A&M University (with Jeffrey S Morris and Raymond J. Carroll). Current position: Teaching Assistant Professor, Department of Statistics, Rice University
- Soyeon Kim (Phd, 2015), Rice University (with J Jack Lee). Current position: Post-doctoral Fellow, University of Pittsburgh Winner of ASA Statistics and Data Mining Student Paper Competition
- Youyi Zhang (PhD, 2018) GSBS (with J. S. Morris) Current position: Senior Data Scientist, Johnson & Johnson Winner of ASA Statistics in Imaging Student Paper Competition
- Neel Desai, Rice University (PhD 2021; with J.S. Morris). Current position: Postdoctoral Fellow, University of Pennsylvania
- Rupam Bhattacharya (PhD 2023; with N. Henderson), University of Michigan. Current position: Postdoctoral Fellow, University of Michigan Medical School (with Arul Chinnayan)
- Tsung-Hung Yao (PhD 2023; with Z. Wu), University of Michigan. Current position: Postdoctoral Fellow, UT MD Anderson Cancer Center.
- Nathaniel Osher (PhD 2025; with Jian Kang), University of Michigan; Current position: Biostatistician, Servier Pharmaceuticals
- Liying Chen (2020+), University of Michigan. ENAR Distinguished Paper Award
- Qingzhi Liu (2020+), University of Michigan; co-advised with Gen Li. ENAR Distinguished Paper Award
- Jessica Aldous (2023+) University of Michigan; co-advised with Michele Peruzzi
- Grant Carr (2023+) University of Michigan; co-advised with Jian Kang
- Maria Murphy (2024+) University of Michigan; co-advised with Dylan Cable
- Ph.D. Students (as external collaborator)
- Karthik Bharath, 2011-2014, Department of Statistics, University of Connecticut, Currently Assistant Professor, Department of Statistics, Nottingham University.
- Adrian Coles, 2012-2015, Dept. of Statistics, North Carolina State University
- Clemontina A. Davenport, 2013-2014, Dept. of Statistics, North Carolina State University
- Sanvesh Srivastava, 2012-2015, Dept of Statistics, Purdue University; Currently Assistant Professor, University of Iowa
- Karl Gregory, 2012-2015, Dept. of Statistics, Texas A & M University; currently Assistant Professor, University of South Carolina
- Chiyu Gu 2015-2018, Dept. of Statistics, University of Missouri
- Carlos Zanini, 2018-present, Dept. of Statistics and Data Sciences, UT Austin
- Masters Students Supervision
- Vinicius Bonato (M.S. 2010) Graduate School of Biomedical Sciences (joint advisor with Kim-ahn Do)
- Lori Jackson (M.S. 2007) UT Graduate School of Biomedical Sciences
- Sunyi Chi, University of Michigan
- Liying Chen, University of Michigan
- Qingzhi Liu, University of Michigan
- Kirrill Sabitov, University of Michigan
- Justice Akuoko-Frimpong, University of Michigan
- Research/Rotation/Intern Students
- Neel Desai [2017]; Chiyu Gu [2016-17]; Yabo Niu [2017]; Youyi Zhang (PhD) [2014]; Adrian Coles [2013]; Sanvesh Srivastava [2012]; Karl Gregory [2012]; Karthik Bharath [2011]; Yanqing Wang [2011]; Lin Zhang [2010]; Mario Navas [2010]; Rajesh Talluri [2009]; Violeta Henessey [2007]; Chao Gao [2019]; Chinmay Raut [2020-2022]
PROFESSIONAL ACTIVITIES AND ACADEMIC SERVICE
- Study Section and Review Panels
- CSR Special Emphasis Panel ZRG1 BDA-A (58) R, NIH, Ad Hoc Member, Biostatistics reviewer, 2009
- National Science Foundation, Statistical Panel B, National Science Foundation, Member, 2012-2013
- Study section member NIH ZHD1 DRG-H (92) B, NIH, Member, 2013-2014
- Biostatistical Methods and Research Design Study Section [BMRD], NIH, Ad Hoc Member, 2014, 2019
- Genomics, Computational Biology and Technology Study Section [GCAT], NIH, Ad Hoc Member, 2014
- Special Emphasis Review Panel, NIH Global ”Omics” Approaches Targeting Adverse Pregnancy and
- Neonatal Outcomes Utilizing Existing Cohorts, 2015-2016
- Grant reviewer for Florida Department of Health Biomedical Research Programs, 2015,2020,2021
- Grant Reviewer for Cancer Prevention Research Opportunity (CPRO); Alberta Cancer Prevention Legacy Fund 2015
- Grant Reviewer for Research Initiation Awards for Historically Black Colleges and Universities, National Science Foundation, 2015
- NSF/NIGMS Panel, 2016
- Cancer Target Discovery and Development Network (U01s) Study Section, 2017
- Scientific Review panel, NCI Informatics Technologies for Cancer Research and Surveillance, 2019
- External Advisory Board Member, Cambridge University, UK, 2019-2024
- External Advisory Board Member, UT MD Anderson Sarcoma SPORE, 2019
- National Cancer Institute Program Project (P01) Review Panel, 2020, 2021
- American Society of Clinical Oncology, Conquer Cancer’s Grants Selection Committee, 2023-2025
- Co-Chair, Scientific Review panel, NCI Informatics Technologies for Cancer Research, 2023
- Program Committee, Biomedical Engineering and Informatics Conference 2009
- Session organizer, Frontiers of Interface between Statistics and Sciences, 2009
- Session organizer, IISA Conference, 2010; JSM 2010; JSM 2012; ENAR 2011, ENAR 2012, JSM 2014, ISBA 2012, IISA 2017
- Session co-organizer, Eastern North American Region (ENAR) Spring Meeting, Atlanta, GA, 2007 Session Chair - IBS 2006; ENAR 2006,2007; JSM 2006, 2007, 2010, 2012,2013, 2014
- Scientific Committee Member, Conference on Latent Gaussian Models, Reykjavik,Iceland
- Program Committee Member, Integrative Biostatistics Research for Imaging, Genomics & High-throughput Technologies in Precision Medicine (iBRIGHT) conference, MDACC
- Program Committee Member for International Indian Statistical Association (IISA) 2015
- Program Committee Member, IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS), 2012 and 2013
- Co-leader, Statistical Challenges in Omics Data Integration Working group, SAMSI, 2015
- Organizing Committee member, ENAR Junior Researchers Workshop, 2015
- Associate Program Chair, Joint Statistical Meetings, 2016
- Program Chair, ENAR, Atlanta, 2018
- Organizing Committee Member, iBRIGHT, Houston, 2019
- Program Chair, IISA, Mumbai, 2019
- Advisory/Executive/Leadership Committees
- Heart of Leadership program, UT MD Anderson Cancer Center, 2015
- External tenure review member, Memorial Sloan Kettering Cancer Center & Oregon State University
- Executive Board Member, International Indian Statistical Association, 2008-2012
- Treasurer, Houston Chapter of the American Statistical Association, 2006-2008
- Co-leader, TCGA Data Integration working group, Statistical and Applied Mathematical Sciences Insti- tute (SAMSI), 2014-2015
- Chair, Faculty Search Committee, Department of Biostatistics, University of Michigan, 2019-2021.
- Chair, ASA Committee for Funded Research, 2024-2025 (member since 2019)
- Member, Regional Committee (RECOM), ENAR, 2023+
- Member, Professional Conduct Committee, International Society for Bayesian Analyses, 2023+
- Institutional Service at University of Michigan
- Member, Executive Committee for School of Public Health, 2021-2023
- Research Council, School of Public Health, 2020-2021
- Chair & Member, Faculty Search Committee, Department of Biostatistics, 2018-2021
- Member, Curriculum Committee, Department of Biostatistics, 2018-2020
- Grant Reviewer, MICHR Pilot Grant Program – Promoting Progress in Statistics Award, 2018
- Member, Cancer Research Committee, UM Rogel Cancer Center, 2018+
- Institutional Service at UT MD Anderson Cancer Center
- Member of Clinical Research Committee, 2011 –2018
- Member of Faculty Senate, 2010-2014
- Member of Multidisciplinary Research Advisory Committee (MRAC), 6/2011 – 2014
- Member of Data and Safety Monitoring Board, 9/2011 – 2013
- Seminar Coordinator, Department of Biostatistics, 2006 – 2012
- Biostatistics co-leader, Multiple Myeloma and Melanoma Moonshot Programs, 2013-present
- Member Faculty Search committee 2012-2014; mid-tenure review committee for various junior faculty
EDITORIAL ACTIVITIES
Editorial Board(s)
- Associate Editor, International Statistical Review (current)
- Associate Editor, Statistics and Data Science in Imaging (current)
- Associate Editor, Annals of Applied Statistics (2018-2025)
- Associate Editor, Nature Scientific Reports (2018-2022)
- Associate Editor, Biometrics (2012-2018)
- Associate Editor, Journal of American Statistical Association – Applications & Case Studies (2014-2018)
- Associate Editor, Sankhya Series B (2012-2018)
- Guest Editor, Cancer Informatics, Libertas Academica, 2013
Journal Reviewer
Annals of Applied Statistics, Australian and New Zealand Journal of Statistics, Biometrics, Canadian Journal of Statistics , Cancer Informatics, Communications in Statistics – Theory and Methods, Com- putational Statistics and Data Analysis, Human Heredity, Journal of American Statistical Association - Theory & Methods and Applications & Case Studies, Journal of Computational and Graphical Statistics, Journal of Multivariate Analysis, Journal of the Royal Statistical Society - Series B and C, Statistics in Medicine, Genetic Epidemiology, Blood, AISTATS
Book Chapter Reviewer: Elsevier: Amsterdam; Chapman & Hall/CRC
TEACHING
University of Michigan
- Generalized Linear Models, Winter 2019, 2020, 2021, 2022, 2023, 2024
- Bayesian Linear Models, Michigan Institute for Clinical & Health Research (MICHR) Workshop, 2019
- Guest Lecturer, Seminar in Cancer Biostatistics, 2018, 2019
- Guest Lecturer, Big Data Summer Institute 2018,2019, 2021, 2022, 2023, 2024
University of Texas Graduate School of Biomedical Sciences and Rice University
- Bayesian Data Analysis (graduate course) Fall 2008, Fall 2009, Fall 2010, Spring 2012, Fall 2013
- Advanced Statistical Methods for the Analysis of Gene Expression and Proteomics, Spring 2008
Texas A&M University
- Elementary Statistical Inference, Fall 2001
Other
- Workshop on Biomedical Big Data and Biostatistics, West China University, 2019
- Tutorial on Integrative Analyses of High-throughput Multi-platform Genomics Data, ENAR, 2018
- Workshop on Network-based Bayesian Models for High-dimensional Genomics Data, Australia, 2017
- Webinar on Bayesian models for high-dimensional genomics data, Bayesian forum at Ely Lilly, 2011
- Webinar on Bayesian modeling of high-dimensional object data, (SAMSI), 2011
- Short course on Statistical Methods for Genomics Data, University of Puerto Rico, 2006
- TA and tutor for numerous introductory and intermediate statistics courses at University of Rochester and Texas A&M University
ACADEMIC PRESENTATIONS
National or International Conferences and Workshops (invited)
- Keynote Speaker, 13th International Conference on Intelligent Biology and Medicine (forthcoming)
- Summer school on Bayesian modeling, computation and applications, Vietnam 2025 (forthcoming)
- Joint Statistical Meetings, 2025 (forthcoming)
- MiRcore Summer Camp for High School students (2024)
- Eastern North American Region Spring Meetings, 2024
- Joint Statistical Meetings, 2024
- Bayesian Biostatistics Conference, Utrecht, 2023
- International Society for Clinical Biostatistics Conference, Milan, 2023
- Eastern North American Region Spring Meetings, 2023
- Joint Statistical Meetings, 2023
- Statistics Workshop, King Abdullah University Of Science And Technology, Saudi Arabia, 2022
- Big Data Summer Institute, University of Michigan, 2022
- Statistics for Oncology (Stat4Onc), University of Chicago, 2022
- Statistical Methods in Genetic/Genomic Studies Workshop, Singapore, 2022 (virtual)
- Eastern North American Region Spring Meetings, 2022
- Joint Statistical Meetings, American Statistical Association, 2022
- Eastern North American Region Spring Meetings, 2021 (virtual)
- Joint Statistical Meetings, American Statistical Association, 2020 (virtual)
- Eastern North American Region Spring Meetings, 2020 (virtual)
- Computational Medicine Conference, University of Pittsburgh, 2019
- International Conference on Bayesian Nonparametrics, Oxford, UK, 2019
- Workshop on Biomedical Big Data and Biostatistics, Chengdu, China, 2019
- Cells to Society Seminar, University of Michigan, 2019
- Conference Board of the Mathematical Sciences (CBMS) Conference: Elastic Functional and Shape Data Analysis, Columbus, 2018
- Joint Statistical Meetings, American Statistical Association, Vancouver, 2018
- International Conference on Big Data and Information Analytics, Houston, 2018
- Keynote Speaker, Genome Engineering for Cancer Treatment, Canberra, Australia, 2017
- ERCIM/CMS Stats, London, 2017
- IISA Annual Meeting, Hyderabad, 2017
- Workshop on Applications-Driven Geometric Functional Data Analysis, Tallahassee, 2017
- ISI World Statistics Congress, Morocco, 2017
- Southern Regional Council on Statistics, Jekyll Island, 2017
- American Association for the Advancement of Science Annual Meeting, 2017
- 2nd Seattle Symposium on Health Care Data Analytics, 2016
- SIAM Conference on Uncertainty Quantification (UQ16), Lausanne, Switzerland, 2016
- Joint Statistical Meeting, Chicago, 2016
- ISNPS Meeting, Avignon, France, 2016
- ISBA World Meeting, Sardinia, 2016
- ICSA Meeting, Shanghai, 2016
- International Indian Statistical Association Conference, Pune, India, 2015
- Alan Gelfand’s 70th Birthday Conference, 2015
- International Society for Non-Parametric Statistics (ISNPS) meeting, Graz, Austria
- Panel on Big Data, ISNPS Meeting, Austria, 2015
- Joint Statistical Meeting, Seattle, 2015
- Asian Regional Section of the IASC meeting, Singapore, 2015,
- iBRIGHT conference, Houston, 2015
- Institute of Applied Statistics Sri Lanka (IASSL) Conference, Colombo, Sri Lanka, 2014
- Joint Statistical Meetings, Boston, 2014
- International Biometric Society Conference, Florence, Italy, 2014
- Bioinformatics: Opening Workshop, SAMSI, 2014
- International Bayesian Meeting, Cancun, Mexico, 2014
- ISBIS 2014 and SLDM Meeting, Durham, North Carolina, 2014
- Eastern North American Region Spring Meetings, 2014
- Bayesian Biostatistics and Bioinformatics Conference, Houston, Texas, 2014
- STATISTICS 2013, C R Rao Institute, Hyderabad, India, 2013
- ICSA/ISBS Joint Statistical Conference, Washington, DC, 2013
- Joint Statistical Meetings, Montreal, Canada, 2013
- Latent Gaussian Models, Reykjavik, Iceland, 2013
- Bayesian methods in Biostatistics and Bioinformatics, IRB, Barcelona, Spain, 2012
- IEEE International Workshop on Genomic Signal Processing and Statistics, Washington DC, 2012
- Biotechnology and Bioinformatics Symposium, Provo, UT, 2012
- Interface 2012, Houston, Texas, 2012
- International Society for Bayesian Analysis (ISBA) World Meeting, 2012
- Joint Statistical Meetings, San Diego, 2012
- Eastern North American Region Spring Meetings, Washington D.C., 2012
- New Grantee Workshop, National Cancer Institute, 2011
- Joint Statistical Meetings, Miami, 2011
- 8th Workshop on Bayesian Nonparametrics, Veracruz, 2011
- IISA Conference, Raleigh, NC, 2011
- Eastern North American Region Spring Meetings, Miami, 2011
- Eighth ICSA International Conference, Guangzhou, China, 2011
- Eastern North American Region Spring Meetings, New Orleans, 2010
- Frontier of Statistical Decision Making and Bayesian Analysis, San Antonio, 2010
- International Indian Statistical Association (IISA) Conference, Vishakapatnam, 2010
- Frontiers of Interface between Statistics and Sciences, Hyderabad, 2010
- Joint Statistical Meetings, Washington D.C, 2009
- Bayesian Biostatistics Conference, UT MD Anderson Cancer Center, 2009
- 9th World Conference of the International Society for Bayesian Analysis (ISBA), 2008
- Southern Regional Council on Statistics Summer Research Conference (SRCOS), 2008
- International Indian Statistical Association (IISA) Conference, Storrs 2008
- International Conference on Statistical Paradigms, ISI Kolkata, 2008
- Joint Statistical Meetings, Salt Lake City, Utah, 2007
- International Indian Statistical Association (IISA) Conference, Cochin 2007
- Eastern North American Region Spring Meetings, Tampa, 2006
- International Biometric Conference in Montre`al, Que´bec, Canada, 2006
Academic Departments (invited)
- Department of Biostatistics, Brown University, 2025 (forthcoming)
- Andrei Yakovlev Colloquium, Department of Biostatistics, University of Rochester, 2024
- Department of Biostatistics, Virginia Commonwealth University, 2023
- Epidemiology & Biostatistics Cancer Imaging Research Center, WUSTL, 2023
- Division of Biostatistics, University of Pennsylvania, 2022
- Department of Bioinformatics, Tools & Technology Seminar, University of Michigan, 2021 (virtual)
- Michigan Institute for Data Science, 2020 (virtual)
- Department of Statistics, Texas A&M University, 2020 (virtual)
- Myrto Lefkopoulou Distinguished Lectureship, Harvard University, 2019
- Department of Statistics & Probability, Michigan State University, 2019
- Department of Statistics & Data Science, UT Austin, 2019
- University of Michigan Precision Health Seminar, 2019
- Cancer Biology/Cancer Genetics Program Meeting, University of Michigan, 2019
- Department of Computational Medicine and Bioinformatics, University of Michigan, 2018
- Department of Statistics, Virginia Tech University, 2018
- Annual Theodore G. Ostrom Lecture, Washington State University, 2018
- CSIRO Research Group, Brisbane, Australia, 2017
- Department of Biostatistics, University of Michigan, 2017
- Department of Biostatistics, Columbia University, 2017
- Department of Biostatistics, Fred Hutchinson Cancer Center, 2015
- Department of Statistics, Rutgers University, 2015
- UT MD Anderson Grand Rounds, 2015
- Department of Biostatistics, Memorial Sloan Kettering Cancer Center, 2015
- Department of Biostatistics, Columbia University, 2015
- Department of Statistics, Purdue University, 2013
- Department of Statistics & Computer Science, C.R.Rao Institute of Mathematics, Hyderabad, India, 2012
- Public Health Foundation of India, New Delhi, 2012
- Department of Statistics, North Carolina State University, Raleigh, NC, 2012
- Department of Biostatistics, UT School of Public Health, Houston, TX, 2012
- Department of Electrical Engineering, Texas Tech University, Lubbock, TX, 2012
- Department of Statistics, University of Texas at Austin, TX, 2012
- Department of Biostatistics, University of California, Davis, 2012
- Department of Statistics, University of Connecticut, 2011
- Machine learning group, Eli Lilly and Company, 2011 (via web broadcasting)
- School of Mathematics, Statistics & Actuarial Science, University of Kent, UK, 2010
- Department of Statistics, University of Oxford, UK, 2010
- Department of Management Science and Statistics, University of Texas at San Antonio, 2008
- Department of Epidemiology, UT MD Anderson Cancer Center, 2008
- Department of Biostatistics, UT School of Public Health, Houston 2008
- Department of Statistics, Rice University, 2008
- Department of Computer Science, University of Houston, 2008
- Department of Statistics, University of Missouri - Columbia, 2008
- Indian School of Business, Hyderabad, India, 2007
- Department of Statistics, University of Puerto Rico - Mayaguez Campus, 2006
- School of Medicine, University of Puerto Rice - San Juan Campus, 2006
- Richard F. Barry Mathematics & Statistics Colloquium, Old Dominion University, 2005
- Department of Statistics, University of Kentucky, 2005
- Department of Biostatistics, Section on Statistical Genetics, University of Alabama, 2005
- Department of Statistics, Michigan State University, 2005
- Department of Biostatistics, University at Buffalo The State University of New York, 2005
- Division of Biostatistics, University of Minnesota, 2005
- Department of Statistics, University of California, Riverside, 2005
- Department of Biostatistics & Applied Mathematics, M. D. Anderson Cancer Center, 2005
- Department of Integrative Studies , Arizona State University West, 2005
- Statistics and Data Mining Research, Bell Laboratories, 2005
- Department of Statistical Science, Southern Methodist University, 2005
- Department of Statistics, Texas A&M University, 2004
Academic Presentations (contributed)
- Joint Statistical Meetings, Denver, Colorado 2008
- Ninth Case Studies in Bayesian Analysis Meeting, Pittsburgh, 2007
- Joint Statistical Meetings, Seattle, Washington 2006
- Joint Statistical Meetings, Toronto, Canada 2004
- International Workshop on Bayesian Data Analysis, Santa Cruz, 2003
- Joint Statistical Meetings, San Francisco, 2003
- Summer Research Conference in Statistics (SRCOS), Jekyll Island, 2003
- Conference of Texas Statisticians, Texas A&M University, 2003
- Department of Biostatistics, University of Rochester, 2000