CADENCE LEPSIG

CML DATA TRACKER

RBC

Red Blood Cell

HB

Hemo

globin

HCT

Hematocrit

MCHC

Mean Cell Hem.

Conc.

RDW

RBC Dist

Width

WBC

White Blood Cell

ANC

Abs. Neut

ALCT

Abs.

Lymph

AMCT

Abs.
Monocytes

PLT

Platelet

MCV

Mean Cell

Vol.

ALP

Alk.

phosphatase

LDH

Lac.

dehydrogenase

BRB

Bilir-

ubin

PCR

%IS

REFERENCE RANGES

3.9-5.6

120-160

0.330-0.470

313-344

11.5-14.8

4.0-11.0

2.0-7.5

1.5-4

0.20-0.80

150-400

80-95

40-150

125-220

<22

DATE

NOTES

01/17/18

Physical abnormalities first detected

*Dynacare (DC)

4.0

111

.36

311*L

18.2*H

59.9*H

40.1*H

2.4

1.8*

H

597*H

90

80

6

01/20/18

ER Visit

 Abdominal Pain

*Lakeridge (LR)

4.27

119*L

0.372

321

17.9*H

66.5*H

573*H

87.2

01/23/18

First Visit

Dr. Kopolovic (LR)

4.24

119*L

.370

322

17.8*H

65.5*H

56.1*H

7.86*H

1.31*H

595*H

87.2

01/30/18

Bone Marrow Biopsy

111*L

61.7*H

33.9*H

7.4*

H

1.85*H

549*H

88.5

02/12/18

DIAGNOSED WITH CML- CP

03/01/18

STARTED TREATMENT WITH SPRYCEL 100MG/DAILY

03/13/18

Follow up (LR)

Two weeks @ Sprycel 100mg/daily

3.6*L

107*

L

0.32*L

332

17.5*H

28.2*H

21.7*H

406*H

88.8

04/05/18

Follow up (LR)

Four weeks @ Sprycel 100/mg/daily

3.4*L

106*

L

.316*L

336

17.4*H

2.8*L

1.1*L

1.6

0.1

*L

102*L

91.9

92

7

>10

        CADENCE LEPSIG        

CML DATA TRACKER

RBC

Red Blood Cell

HB

Hemo

globin

HCT

Hematocrit

MCHC

Mean Cell Hem.

Conc.

RDW

RBC Dist

Width

WBC

White Blood Cell

ANC

Abs. Neut

ALCT

Abs.

Lymph

AMCT

Abs.
Monocytes

PLT

Platelet

MCV

Mean Cell

Vol.

ALP

Alk.

phosphatase

LDH

Lac.

dehydrogenase

BRB

Bilir-

ubin

PCR

%IS

REFERENCE RANGES

3.8-5.6

120-160

0.330-0.470

313-344

11.5-14.8

4.0-11.0

2.0-7.5

1.5-4

0.20-0.80

150-400

80-95

40-150

125-220

<22

DATE

NOTES

04/18/18

Follow up (LR)

Six weeks at Sprycel @100mg

3.52*L

111

*L

0.331

336

17.5

*H

3.6

*L

1.6

*L

1.8

0.1

*L

65

*L

93.9

106

6

TWO WEEK BREAK FROM 100MG/ SPRYCEL

05/02/18

Follow up (LR)

Two weeks off Sprycel @100mg

3.54*L

110

*L

0.335

328

16.3

*H

2.4

*L

1.4

0.1

*L

144

*L

94.6

86

5

BEGIN SPRYCEL AT 50MG/ DAY

05/16/18

Follow up (LR)

Two weeks on

Sprycel @ 50mg

3.68
*L

117

*L

0.344

339

15.2

*H

2.6

*L

0.96*L

1.59

0.05

*L

94

*L

93.5

5

BEGIN SPRYCEL AT 50MG/ EVERY OTHER DAY

05/29/18

Follow up (LR)

Two weeks on
Sprycel @ 50mg Every Other Day

3.87

124

0.359

347

*H

14.7

1.6

*L

0.61

*L

0.99

*L

75

*L

92.8

10

ONE WEEK BREAK FROM 50MG/ SPRYCEL EVERY OTHER DAY - RESUMED AT 20MG/DAILY JUNE 4TH

06/16/18

Follow up (LR)

Nearly Two weeks on Sprycel @20mg/ Day

3.67

*L

119

*L

0.346

343

15.5

*H

3.0

*L

0.72

*L

2.25

0.03

*L

122

*L

94.1

80

11

>10

CADENCE LEPSIG

CML DATA TRACKER

RBC

Red Blood Cell

HB

Hemo

globin

HCT

Hematocrit

MCHC

Mean Cell Hem.

Conc.

RDW

RBC Dist

Width

WBC

White Blood Cell

ANC

Abs. Neut

ALCT

Abs.

Lymph

AMCT

Abs.
Monocytes

PLT

Platelet

MCV

Mean Cell

Vol.

ALP

Alk.

phosphatase

LDH

Lac.

dehydrogenase

BRB

Bilir-

ubin

PCR

%IS

REFERENCE RANGES

3.9-5.6

120-160

0.330-0.470

313-344

11.5-14.8%

4.0-11.0

2.0-7.5

1.5-4

0.20-0.80

150-400

80-95

40-150

125-220

<22

DATE

NOTES

07/03/18

Follow Up (LR)

One Month on Sprycel @ 20mg/ Day

3.54*L

118

*L

0.340

346

*H

16.6

*H

2.6

*L

0.68*L

1.92

0.03

*L

72

*L

96.1*H

76

13

07/27/18

Follow Up (LR)

Two Months on Sprycel @ 20mg/ Day

2.93*L

101

*L

0.289*L

349

*H

19

*H

2.93

*L

0.55

*L

1.80

0.05

*L

41

*L

98.6*H

86

HOLD SPRYCEL AND WAIT FOR PMH REFFERAL

08/01/18

First Visit

Dr. Lipton at

Princess Margaret (PMH)

3.07*L

108

*L

0.3

*L

356

*H

19.5

*H

2.6

*L

0.5

*L

2.0

0.1

*L

38

*L

98.6*H

96

190

13

>10

08/22/18

Follow Up (PMH)

Almost one month off of Sprycel

2.83*L

102

*L

0.3

*L

344

20

*H

2.0

*L

0.6

*L

1.3*L

0.1

*L

97

*L

105

*H

72

218

12

CONTINUE TO HOLD SPRYCEL AND WAIT FOR PLATELET AGGREGATION STUDIES  -  SUPPLEMENT WITH B12

09/05/18

Follow Up (PMH)

Almost Six Weeks Off Sprycel

2.68*L

97

0.28

*L

342

18.3

*H

2.9

*L

1.2

*L

1.5

0.2

*L

111

*L

105.5

*H

CADENCE LEPSIG

CML DATA TRACKER

RBC

Red Blood Cell

HB

Hemo

globin

HCT

Hematocrit

MCHC

Mean Cell Hem.

Conc.

RDW

RBC Dist

Width

WBC

White Blood Cell

ANC

Abs. Neut

ALCT

Abs.

Lymph

AMCT

Abs.
Monocytes

PLT

Platelet

MCV

Mean Cell

Vol.

ALP

Alk.

phosphatase

LDH

Lac.

dehydrogenase

BRB

Bilir-

ubin

PCR

%IS

REFERENCE RANGES

3.9-5.6

120-160

0.330-0.470

313-344

11.5-14.8%

4.0-11.0

2.0-7.5

1.5-4

0.20-0.80

150-400

80-95

40-150

125-220

<22

DATE

NOTES

BEGIN DASATINIB 20MG/ EVERY OTHER DAY STARTING SEPT 12/18

10/03/18

Follow Up (PMH)
8 weeks total off Sprycel. Have now reintroduced Sprycel 20MG/ Every other day for 3 weeks.

3.42*L

124

0.37

337

15

*H

2.9

*L

1.3

*L

1.5

0.2

111

*L

107.2

*H

71

213

11

BEGIN DASATINIB 20MG/ 4 DAYS A WEEK (MON/WED/FRI/SUN)

10/31/18

Follow Up (PMH)

One Month at Sprycel 20MG/ 4 Days a week

3.69*L

127

0.38

331

14.1

2.7

*L

1.0

*L

1.5

0.2

92

*L

104

*H

82

164

8

>10

11/28/18

Follow Up (PMH)

Two Months at 20MG/ 4 days a week

3.75*L

127

0.37

341

14.5

2.3

*L

0.7

*L

1.4

*L

0.1

*L

68

*L

99.3

*H

12/12/18

Follow Up (PMH)
10 weeks at 20/mg/ 4 days a week

3.57

*L

121

.35

343

14.6

3.5

*L

1

*L

2.2

.2

81

*L

98.4*H

83

142

8

BEGIN DASATINIB 20MG/ 5 DAYS A WEEK (SUN/MON/WED/THURS/FRI)

CADENCE LEPSIG

CML DATA TRACKER

RBC

Red Blood Cell

HB

Hemo

globin

HCT

Hematocrit

MCHC

Mean Cell Hem.

Conc.

RDW

RBC Dist

Width

WBC

White Blood Cell

ANC

Abs. Neut

ALCT

Abs.

Lymph

AMCT

Abs.
Monocytes

PLT

Platelet

MCV

Mean Cell

Vol.

ALP

Alk.

phosphatase

LDH

Lac.

dehydrogenase

BRB

Bilir-

ubin

PCR

%IS

REFERENCE RANGES

3.9-5.6

120-160

0.330-0.470

313-344

11.5-14.8%

4.0-11.0

2.0-7.5

1.5-4

0.20-0.80

150-400

80-95

40-150

125-220

<22

DATE

NOTES

12/20/18

CBC Check by another physician  

3.3

*L

111

*L

0.33

339

14.1

2.4

*L

.9

*L

1.3

*L

.1

*L

62

*L

99.1

*H

9/1/19

Follow Up (PMH)
4 weeks at 20/mg/  5 days a week

3.48

*L

118

*L

0.35

342

16.5

*H

3.3
*L

1.2

*L

1.9

.2

68

*L

99.5

*H

82

194

7

PROCEEDING TO TRANSPLANT- CONTINUE SPRYCEL AT 20MG 5/WEEK AND AWAIT TRANSPLANT TEAM CONTACT

22/1/19

Transplant Consult  @ PMH with
Dr. Kumar Rajat 
6 weeks at 20/mg/  5 x week

3.38
*L

115
*L

.34

342

17.3
*H

2.8
*L

1.1
*L

1.6

.1
*L

60

99.8
*H

66

180

13

CONTINUE SPRYCEL AT 20MG 5/WEEK AND AWAIT TRANSPLANT

20/2/19

Follow Up (PMH)
10 weeks at 20/mg/  5 x week

3.13
*L

111
*L

.32
*L

349
*H

16.1
*H

2.4
*L

1
*L

1.3
*L

.1
*L

52

102.2
*H

69

195

11

>10

CONTINUE SPRYCEL AT 20MG 5/WEEK AND AWAIT TRANSPLANT

04/3/19

Transplant Pre-Assessment Bloodwork (PMH)

3.24
*L

115
*L

.34

340

16
*H

2.2
*L

.7
*L

1.4
*L

.1
*L

51

104.4
*H

76

211

7

CADENCE LEPSIG

CML DATA TRACKER

RBC

Red Blood Cell

HB

Hemo

globin

HCT

Hematocrit

MCHC

Mean Cell Hem.

Conc.

RDW

RBC Dist

Width

WBC

White Blood Cell

ANC

Abs. Neut

ALCT

Abs.

Lymph

AMCT

Abs.
Monocytes

PLT

Platelet

MCV

Mean Cell

Vol.

ALP

Alk.

phosphatase

LDH

Lac.

dehydrogenase

BRB

Bilir-

ubin

PCR

%IS

REFERENCE RANGES

3.9-5.6

120-160

0.330-0.470

313-344

11.5-

14.8%

4.0-11.0

2.0-7.5

1.5-4

0.20-0.80

150-400

80-95

40-150

125-220

<22

DATE

NOTES

13/03/19

Emergency Room Visit (LAKERIDGE)

3.01

*L

107

*L

0.314

*L

340

16.1

*H

1.7

*L

1.38

*L

0.20

*L

.12

*L

38

*L

104.3

*H

8

20/03/19

Follow Up (PMH)
14 weeks at 20/mg/  5 x week

3.33

*L

118

*L

0.34

345
*H

15.3

*H

2.7
*L

0.8
*L

1.8

0.1
*L

47
*L

103
*H

70

9