Research Grants

Completed

1.The role of STAT-1 targeted miRNA in endometrial cancer (Geran Penyelidik Muda). RM50,000.

UKM-GGPM-TKP-027-2011-2. Principle investigator

2.The role of miRNA involved in survival of lung cancer patients (FRGS). RM182,000. FRGS/1/2011/SKK/UKM/03/16. Principle investigator

3.Serum miRNA profiling in Malay Early Onset-Parkinson’s Disease. RM95,000

GUP-2015-040. Principle investigator

4.Mechanism of LDLR and PCSK9 gene mutations in hypercholesterolemia using CRISPR-Cas9 System. RM190,700. FRGS/1/2015/SKK08/UKM/03/3. Principle investigator.

5.Exploring The Relationship between Micrornas and Their Targeted mRNA in Metastatic Epithelial Ovarian Cancer Genes. RM142,000.  ERGS/1/2012/SKK01/UKM/02/4. Co-investigator.

6.Roles of MicroRNAs in Regulation the Cell Adhesion Associated Genes (VCL and CX3CL1) in the Development of Prostate Cancer and Bone Metastases Prostate Cancer. RM20,000. FF-256-2011. Co-investigator.

7.The Role of MicroRNA in Regulating SCL16A1, TBX3 and AXIN2 Genes in Endometrial Cancer. RM20,000. FF-293-2011. Co-investigator.

8.Characterisation of Common Transcription Factor Binding Sites for Colorectal Cancer-Related Genes. RM63,775.  JJ-002-2011. Co-investigator.

9.Identification of Genes That Sensitise Glioblastoma Multiforme Cell Lines to Chemotherapy. RM 36,600. JJ-008-2011. Co-investigator.

10.Exploring the relationship between microRNAS and their targeted mRNA in common metastatic cancer genes. RM30,000. UKM-GUP-2011-286. Co-investigator.

11.Genetic modifiers of HbF and phenotypic severity in Malaysian beta-thalassaemia patients. RM100,000. FRGS/2/2014/SKK09/UKM/01/1. Co-investigator.

12.The role of BDNF biomarkers in the management of suicidal ideation with ketamine versus electroconvulsive therapy in treatment resistant depression. RM97,000.  FRGS/2/2014/SKK09/02/1. Co-investigator.

13.The expression of oxidative stress biomarkers as the predictive measures for suicide attempts among bipolar disorder patients: interaction with cognitive impulsivity and clinical factors.

RM 70,000.  GUP-2014-048. Co-investigator.

14.Genome wide association study in diabetic. RM 1,200,000. UKM FPR.4/244/FF-205-207. Co-investigator.

15.Whole exome sequencing in Malays with hypercholesterolemia. RM 1,200,000. UKM FPR.4/244/FF-205-207. Co-investigator.

16. RNA interference mediated silencing effects of genes involved in longetivity, DNA repair and locomotion of C.elegans exposed to microgravity and orbital forces. RM528,000. SA1212011. Co-investigator.

17. A study on genotype-phenotype correlation and response to pamidronate treatment among patients with osteogenesis imperfecta in PPUKM. RM163,000. FRGS/1/2015/SKK08/UKM/02/1. Co-investigator.

18. Development of the mobile detection unit consisted of a portable computer controlled high resolution melt (HRM)-realtime PCR system for detection of HLAB-1502 and HLAB-5801. RM142,800. KK-2015-011. Co-investigator.

Ongoing

1.Pre-symptomatic germline gene mutations as biomarkers for cancer prediction. RM100,000. DPP-2018-005. Co-investigator.

2.Candidate Single Nucleotide Polymorphisms (SNPs) and Predictors for Development of Chronic Kidney Disease (CKD) in Type 2 Diabetic Malaysian. RM20,000. FF-2015-389.Co-investigator.

3. Status of combined immunodeficiency in Malaysia: Exploring expression and correlation of clinical phenotypes, genotypes and immunological phenotypes focusing on not yet described entity. RM126,400. FRGS/1/2017/SKK02/UKM/02/3.Co-investigator.

4.Urinary lncRNAs in diabetic nephropathy patients as potential early biomarkers. RM70,000. GUP-2017-020.Co-investigator.

5. Circulating Long Noncoding RNAs As Early Biomarkers For Cardiovascular Progression Among Type II Diabetes Mellitus Patients. RM80,000. GUP-2018-069.Co-investigator.

6. Associations of the common susceptibility risk loci of Systemic Lupus Erythematosus (SLE) with

disease manifestations and treatment response. RM172,500.  FRGS/1/2018/SKK02/UKM/03/1. Co-investigator.

7.Elucidating the methylation and functional changes resulting from hyperglycemic induced pluripotent stem cells (iPSC) reprogramming. RM70,000. GUP-2017-037. Principle investigator

Postgraduate Supervision

Ongoing:

Main supervisor:

  1. Khoo Tze Sean. PhD (Supplementary: Molecular Medicine). UKM.

Co-supervisor:

  1. Associate Prof Dr Fazilah Ahmad. PhD (Molecular Medicine). UKM.
  2. Tamil Selvi Loganathan. Master of Science (Supplementary: Molecular Medicine). UKM

Graduated:

  1. Siti Aisyah Razak. Master of Science (Molecular Medicine). 2018. UKM
  2. Nadiah Mohd Nawawi. Master of Science (Molecular Medicine). 2018. UKM
  3. Nur Fadhlina Mohamad Pakarul Razy. Master of Science (Molecular Medicine). 2017. UKM
  4.  Dr Soon Bee Hong. PhD (Molecular Medicine).2017. UKM.
  5. Dr Kamariah Ibrahim. PhD (Molecular Medicine).2017. UKM.
  6. Mohd Firdaus Che Mat. Master of Science (Molecular Medicine). 2016. UKM
  7. Nor Idayu A. Rahman. Master of Science (Molecular Medicine). 2016. UKM