Lesson 1.1 Teacher’s Guide

Biochemistry: Homeostasis, Feedback Mechanisms, and Diabetes

Standards:

• 9.1.1.1 Science is a way of knowing about the natural world and is characterized by empirical criteria, logical argument and skeptical review.
• 9.1.3.1 Natural and designed systems are made up of components that act within a system and interact with other systems.
• 9.4.1.1 Organisms use the interaction of cellular processes as well as tissues and organ systems to maintain homeostasis.
• 9.4.4.2 Personal and community health can be affected by the environment, body functions, and human behavior.

Benchmarks:

• 9.1.1.1.2 Understand that scientists conduct investigations for a variety of reasons, including: to discover new aspects of the natural world, to explain observed phenomena, to test the conclusions of prior investigations, or to test the predictions of current theories.
• 9.1.3.1.3 Describe how positive and/or negative feedback occur in systems.
• 9.4.1.1.1 Explain how cell processes are influenced by internal and external factors, such as pH and temperature, and how cells and organisms respond to changes in their environment to maintain homeostasis.
• 9.4.4.2.3 Describe how the immune system sometimes attacks some of the body’s own cells and how some allergic reactions are caused by the body's immune responses to usually harmless environmental substances.
• 9.4.4.2.4 Explain how environmental factors and personal decisions, such as water quality, air quality and smoking affect personal and community health.

Tentative Timeline:

1.1a. Homeostasis

• 1.1.1. Introduction (Day 1): quote/image quick write, pre-assessment of learning targets (fill out table), individual pre-assessment of, vocabulary (fill out table), pre-assessment of vocabulary terms (partner brainstorming bubble maps), class discussion of vocabulary terms
• 1.1.2. Homeostasis Overview (Day 2): prior knowledge quick write, read and mark the text, comprehension quick write, video clip from Bozeman Science, summary “text,” vocabulary check
• 1.1.3. Glucose (Day 3): prior knowledge quick write, read and mark the text, fill-in-in-the blank
• 1.1.4. Homeostasis Case Study (Day 4): homeostasis case study from University of Wisconsin, mini formative assessment on homeostasis

1.1b. Diabetes

• 1.1.5. Introduction to Diabetes (Day 5): comprehension quick write, vocabulary check, prior knowledge quick write, prior knowledge quick write, read and mark the text, practice t-chart
• 1.1.6. Complications of Diabetes (Day 6): common complications of diabetes questions, video clip, comprehension/application quick write, vocabulary reflection
• 1.1.7. Diabetes Case Study (Day 7): diabetes case study from the University of Wisconsin
• 1.1.8. Diabetes Article (Day 8): primary source research article assignment and summary, mini formative assessment on diabetes

1.1c. Tying it all together

• 1.1.9. Philosophical Chairs Class Activity (Day 9)
• 1.1.10. and 1.1.11. In-Class Lab Experiment (including teacher's guide) (Days 10-11): “A Scientific Investigation - What Types of Food Contain Starch and Protein?” from the University of Pennsylvania
• 1.1.12. Formative Assessment Unit 1 - Lesson #1 (Day 12)

Additional Activities, Resources and Tips:

• As an extension activity, students can learn about the discovery of insulin by watching the video titled: Milestones in Science & Engineering - Frederick Banting, Charles Best, James Collip, John McLeod - Insulin 

• Another option for encouraging in-class discussion is to allow students to hear the perspectives and experiences from teenagers living with diabetes by having students watch some of the video diaries from the PBS series Living with my type 2. teenage video diaries.

• A non-primary source article can be included for differentiation. Students can read and mark the text for the article titled “Insurance should pay for exercise programs to cut health costs, UF expert says.” 

• Please click here to go to the Google Doc of the teacher prep handout for the experiment titled: “A Scientific Investigation - What Types of Food Contain Starch and Protein?” (by Dr. Ingrid Waldron, Department of Biology, University of Pennsylvania).

• As an extension activity, some students might enjoy playing the interactive “Diabetic Dog” Game.
  
• Content information on Glucose Regulation:
  Norman, James. “Normal Regulation of Blood Glucose.” endocrineweb. Vertical Health LLC, 27 May 2014. Web. 5 August 2014.