Grant Support


Last Update: March 25, 2018

 Active

09/2017-08/2022        Co-Investigator/UPenn Subcontract PI, Whole genome sequencing in ethnically diverse cohorts for the ADSP Follow-Up Study (FUS), NIH/NIA U01-AG057659, $11,819,206 total. (MPI: Margaret Pericak-Vance/Richard Mayeux/Badri Vardarajan).  Budget for Penn: $2,911,918 total.

04/2016-03/2021        MPI, Coordinating Center for Genetics and Genomics of Alzheimer's Disease (CGAD), NIH/NIA U54-AG052427, $11,579,543 total for the entire project over five years (MPI: Gerard Schellenberg/Li-San Wang).

04/2017-03/2022        PI, The NIA Genetics of Alzheimer’s Disease Data Storage Site, NIH/NIA U24-AG041689, $8,229,087 total for years 6-10 (PI: Li-San Wang).

09/2017-07/2022        MPI, Impact of coding and non-coding variation in progressive supranuclear palsy, NIH/NINDS UG3-NS104095, $5,403,697 total for the entire project over five years (MPI: Giovanni Coppola/Gerard Schellenberg/Li-San Wang/Dennis Dickson/Judith Steen).

06/2014-05/2018        Core C Co-Leader, Consortium for Alzheimers Sequence Analysis (CASA), NIH/NIA UF1-AG047133, $12,638,607 over four years for the entire project (Contact PI: Gerard Schellenberg).

07/2017-06/2022        Co-Investigator, Integrated target discovery in Alzheimer's disease, NIH/NIA RF1-AG055477, $2,945,840 total for the entire project over five years (PI: Christopher Brown)

09/2016-08/2020        Co-Investigator, Pleiotropy GWAS of Alzheimer’s Disease and Multiple Neurodegenerative Diseases, NIH/NIA R01-AG054060, $411,294 total each year (PI: Adam Naj).

09/2016-08/2021        Co-Investigator, Identifying genes and pathways that modulate Tau Toxicity in FTD, NIH/NINDS U54-NS100693, $1,244,334 total each year (PI: Leonard Petrucelli).

04/2015-03/2020        Co-Investigator, Alzheimer's Disease Genetics Consortium, NIH/NIA U01-AG032984, annual amount: $4,296,244 total cost for the entire project (PI: Gerard Schellenberg).

10/2012-09/2017        Co-Investigator, Parkinson’s Disease and Dementia, NIH/NINDS P50-NS053488, $1,233,000 direct cost per year for the entire project (PI: John Trojanowski).

07/2016-06/2021        Co-Investigator, Alzheimer's Disease Core Center, NIH/NIA P30-AG010124, annual amount: $1,771,275 total cost per year for the entire project (PI: John Trojanowski). 

 

09/2013-06/2018        Co-Investigator, Frontotemporal Dementias: Genotypes and Phenotypes, NIH/NIA P01-AG017586 , annual amount: $1,791,874 direct cost for the entire project (PI: Virginia Lee).

 

 Completed

 

09/2012-05/2018        Co-Investigator, Role Of Single Cell mRNA Variation In Systems Associated Electrically Excitable Cells, NIH Common fund/NIMH U01-MH098953, $2,311,889 total per year for the entire project (PI: James Eberwine/Junhyong Kim).  

 

09/2012-10/2017        PI, Computational genome-wide RNA profiling using next-generation sequencing, NIH/NIGMS R01-GM099962, $1,560,000 total for the entire project (PI: Li-San Wang).

09/2013-06/2018        Core B Co-Leader, Epigenetics of Aging and Age-associated Diseases, NIH/NIA P01-AG031862 , annual amount: $1,694,237 direct cost for the entire project (PI: Shelley Berger).

04/2012-03/2018        Co-Investigator, Epigenetic Changes Associated with Neurodegenerative Diseases, NIH/NINDS R01-NS078283, $594,745 direct cost per year for the entire project (MPI: Shelley Berger/Brad Johnson/Nancy Bonini).  No cost extension.

04/2012-03/2017        Co-Investigator, 3/3-Sequencing Autism Spectrum Disorder Extended Pedigrees, NIH/NIMH R01-MH094382, $100,000 direct cost per year for the entire project (PI: Gerard-Schellenberg).

04/2012-03/2017        PI, The NIA Genetics of Alzheimer’s Disease Data Storage Site, NIH/NIA U24-AG041689, $6,402,241 total for the entire project over five years (PI: Li-San Wang).

04/2011-03/2016        Co-Investigator, Targeted Proteomics Of Resilient Cognition In Aging, NIH/NIA R01-AG039478, annual amount: $342,941 per year direct cost for the entire project (PI: Steven Arnold).

 

 

03/2011-02/2016        Co-Investigator, Frontotemporal Dementias: Genotypes and Phenotypes, NIH/NIA P01-AG017586, annual amount: $218,236 direct cost per year for the entire project (PI: Virginia Lee, Project PI: Gerard Schellenberg).

04/2009-03/2015        Co-Investigator, Alzheimer's Disease Genetics Consortium, NIH/NIA U01-AG032984, total amount: $18,723,531 total cost for the entire project (PI: Gerard Schellenberg).

09/2011-06/2015        Co-Investigator, Genomic analysis of bipolar disorder in a genetic isolate, NIH/NIMH R01-MH093415, $1,016,386 direct cost per year for the entire project (MPI: MajaBucan/Steven Paul).

02/2011-01/2014        PI, Penn CNDR/Johnson & Johnson Joint Integrative Informatics Research, Program, Johnson & Johnson Pharmaceutical Research and Development, $1,168,104 for the entire project (PI: Li-San Wang).

 

10/2011-09/2013        Co-Investigator, Whole-exome sequencing of Progressive supranuclear palsy, CurePSP, $250,000 per year for the entire project (PI: Gerard Schellenberg).

09/2009-09/2012        Co-PI, Genome wide associate analysis of Alzheimer's Disease, NIH/NIA RC2-AG036528, $3,439,720 direct cost per year for the entire project (PI: Gerard Schellenberg).  

01/2011-12/2011        Co-Investigator, Plasma And Cerebrospinal Fluid (CSF) Parkinson's Disease (PD) Biomarkers For Differential Diagnosis, Disease Progression And Predicting Cognitive Impairment (CI), Penn/Pfizer Alliance, $563,008 direct cost per year for the entire project (PI: John Trojanowski).

 

09/2009-09/2012        Co-Investigator, 4/5 - Elucidating the genetic architecture of autism by deep genomic sequencing, NIH/NIMH 1-R01-MH089004-01, $507,936 direct cost per year for the entire project (PI: Gerard Schellenberg).

 

01/2007-12/2012        Collaborator, Specialized Center of Research in Targeted Therapy for Infant Leukemia, Leukemia & Lymphoma Society, $1,250,000 direct cost per year for the entire project (PI: Carolyn Felix).

 

07/2010-06/2011        PI, Transcriptomic changes in neurodegenerative brain using RNA sequencing, Penn Institute on Aging Pilot Grant, total amount: $50,000 for the entire project (PI: Li-San Wang).

 

01/2010-12/2010        Co-Investigator, Plasma and CSF Biomarkers As Diagnostics For Alzheimer's Disease II: Validation, Disease Specificity, and Prediction of Cognitive Decline, Penn/Pfizer Alliance, $563,008 for the entire project (PI: Steven Arnold).

 

01/2009-12/2010        Co-PI, Genome-wide Analysis of the Double-Stranded RNA Component of Eukaryotic Transcriptomes, Penn Genome Frontiers Institute (PGFI) Pilot Grant, $120,000 for the entire project (PI: Brian Gregory).

 

01/2008-12/2008        PI, Novel Bioinformatic Approaches for Modeling Age-Correlated Gene Expression Progression, University of Pennsylvania Research Foundation Pilot Grant, $24,378 for the entire project (PI: Li-San Wang)

 

07/2007-06/2008        PI, The role of G-quadruplexes in senescence through RecQ-dependent pathways, University of Pennsylvania Institute on Aging Pilot Grant, $50,000 for the entire project (PI: Li-San Wang).

 

01/2007-05/2009        Co-Investigator, The University of Pennsylvania Center of Excellence for Research on Neurodegenerative Diseases, University of National Tobacco Master Settlement Agreement, $1,067,837 per year for the entire project (PI: Chris Clark).