Published using Google Docs
Autosomal Polycystic Kidney Disease
Updated automatically every 5 minutes

Taken from Reference Medscape 2011: Autosomal Polycystic Kidney Disease

Medical Care

Ensure that a patient with ADPKD who is nonhypertensive and has normal renal function undergoes blood testing and ultrasonographic scanning once a year.

Schedule more frequent follow-up studies for patients with high blood pressure. Hypertension is common, occurring in as many as 50-70% of patients before the onset of renal failure.

Patients with renal failure require more frequent monitoring, based on the severity of their condition.

A study by Torres et al identified serum high-density lipoprotein (HDL) cholesterol, urine sodium excretion (UNa V), and 24-hour osmolality as having a likely effect on ADPKD progression.[11] Whether modification of these components influences the clinical course of ADPKD remains unclear.

Medical therapy is necessary to accomplish the following:

Surgical Care

Infected renal or hepatic cysts

Large cysts causing abdominal pain

Massive polycystic liver diseases (See the image below.)



Although a low-salt diet is recommended when hypertension or renal failure is present, no other special diet reportedly is of benefit.


Patients should avoid contact sports in which direct trauma to the back or abdomen is likely. This is especially important with larger, palpable kidneys in order to minimize the risk of rupture