DeSci[a][b][c][d] Wiki
Disclaimer
This wiki is not investment advice, nor does it guarantee the credibility of any of the people mentioned within. In light of the aberrance of scams/scammers in the crypto community, we recommend that you always do your own research. Never share your seed phrase. Always verify before trusting someone you are in contact with.
Updates and General Info
- Last updated 1/19/2024: Added some requested changes/additions, archived some projects, and cleaned out all the miscellaneous spaces and weird edits people have been throwing in here. Please stop doing that. - Jocelynn
- REQUEST: If you scroll by any groups that you know have been shut down or are inactive, please leave a comment. We try to keep track of the status of groups (and check in occasionally), but as this is also community-driven, we would appreciate your help! We will always place them in the Archive section so that we maintain a record of the DeSci evolution ♥
- We made our Figma prep for this image public for viewing, so if you would like to add comments or suggestions, you are welcome to drop them at this link.
- Please comment with missing projects and they will be integrated ~once per week.
- Curated by Jocelynn Pearl
- Decentralized Science Landscape figure is by the UltraRare Bio team including Dani Bergey and Katie Koczera (graphic design)
- Subscribe to UltraRare The Podcast to learn more about DeSci
- Video Explainer from @CoinMarketCap of Decentralized Science - highly recommend listening/watching this!
- Decentralized Science Explainer on Ethereum.org
If reproducing aspects of the wiki, please cite those who contributed. Thank you.
To see the document outline in Google Docs:
- Click the View tab -> Click “show document outline”
- This allows you to jump to a specific section.
- You can also click on any of the links in the Table of Contents below.
Decentralized Science Landscape Image
View the latest version or request logo updates here: UltraRare_DeSci_Landscape
UltraRare Bio curated and updated this DeSci landscape snapshot on August 27, 2023 with helpful feedback from many in the community. There are many projects being built in this space, so we recognize we could have missed some incredibl[j]e projects that deserve to be showcased here. Please add those to the Wiki so we include them in future iterations.
A note on the Communities & Chats category: In an attempt to avoid a NA- & Euro-centric community section in the landscape graphic, we have opted to include geographic DeSci communities of countries or larger. Please see the Community section below to look for DeSci communities in your area.
Table of Contents
Do not directly edit this section; it will auto-update once the added project is accepted. Please enter information about projects into the body of the document - you can get to the appropriate category by using the linked text in the Table of Contents below.
Decentralized Science Landscape Image
Cerebrum DAO (previously CherubsDAO)
Decentralized Science Ecosystems
Articles & Podcasts on Scientific Publishing
UltraRare Podcast: Scientific Publishing is Broken. Can Web3 Fix It?
Tokenized Thought by @0xboodle:
OpenAccessDAO’s Knowledge Resources
Decentralized Biotech / Biopharma
A Guide to Decentralized Biotech
Virtual Drug Development or Clinical Trial Platforms: coming soon
Decentralized Space Exploration projects
Focused Research Organizations & Institutes
Decentralized Financing of Science and/or Philanthropy
Crowd Funded Cures (see above)
GainForest / LabDAO Rainforest Monitoring Lab
Data Storage & Blockchain Protocols
Data Management & Valorisation
With cryptocurrency and NFTs, ‘decentralized science’ seeks to upend drug industry financing.
Molecule Fundraising Announcement
Retroactive Public Goods Funding
How to DAO with People, not just Protocols
Non fungible tokens (NFTs) for academic publications?
How scientists are embracing NFTs
IBFS (Blockchain for Science) First Announcement
Epoch 16 - Decentralized Science - DeSci
DeSci: Can Crypto Improve Scientific Research?
DeSci: How Can DAOs Facilitate Collaboration And Push The Open Science Movement Forward
The New Web 3 Movement to Revolutionize Scientific Research and Funding
How do Decentralized Science Organizations Work
The Rise of DeSci Blockchain and the Future of Research
Why Science? Why Blockchain? Why DAO Now?
Working in Public by Nadia Eghbal
Reinventing Discovery by Michael Nielsen
Reinventing Organizations by Frederic Laloux
Impact Networks by David Ehrlichman
DeSci DAOs
Decentralized autonomous orgs are popping up with various goals within the scientific sphere that range from funding science, disrupting the scientific publishing industry, upholding open science, and pursuing specific research goals like longevity.
AsteriskDAO
AsteriskDAO is addressing the wide knowledge and resource gap in women’s non-reproductive health through worldwide research and IP funding.
AthenaDAO
AthenaDAO is a decentralized community of researchers, funders, and advocates working to advance women’s health research, education, and funding. AthenaDAO primarily funds translational R&D. We are particularly interested in transformational contributions to women’s health. We will also fund more ‘basic’ research that will be critical to moving the needle for science.
Check the Reproductive Health Report
VitaDAO
VitaDAO is a DAO collective for funding longevity research. Our core mission is the acceleration of research and development (R&D) in the longevity space and the extension of human life and healthspan. To achieve this, VitaDAO collectively funds early-stage research projects and spins out startups to commercialize them. It also aims to improve longevity awareness through both scientific and general audience publishing initiatives.
- Website with funded projects, explainers etc. https://www.vitadao.com/
- All links: https://vitadao.com/links
- Governance Proposals: https://gov.vitadao.com/
- Video Podcasts etc. https://www.youtube.com/c/vitadao
- Audio Podcasts: https://anchor.fm/vitadao
- Articles: https://vitadao.medium.com/
- Monthly summary: http://newsletters.vitadao.com/
- Paid on-demand peer review services: The Longevity Decentralized Review (TLDR) and Proof of Peer Review (PoP Review) for longevity research and general biomedical research, respectively.
- The Longevity Journal (link TBD)
Open Science DAO
We're a community-owned open science ecosystem that unlocks data silos, revolutionizes collaboration, and democratizes funding.
Twitter: @OpScientia
News: https://pulse.opsci.io/
Resources:
Shady El Damaty DeSci Stack at MR Hack-a-thon
Shady El Damaty Opscientia at OceanDAO Sailor’s Lounge
Background: Sarah Hamburg Unstoppable Podcast (note - no longer with OpScientia, but this podcast interview was great IMHO)
Opsciverse Project from the Opscientia DAO: "Portal to the world of decentralised laboratories. Powered by the Open Science Framework and running on smart contracts for autonomous research workflows"
Jocelynn’s notes: some of the better conversations around open science and scientific publishing happen on this server. A lot of good chatter around articles related to open science. Focus seems to be decentralized file storage.
The Science DAO
From their whitepaper: A decentralized think tank to foster growth and incubate scientific ideas. DeFi community/DAO to fund scientific research, primarily biomedical.
Currently seeking projects for funding
Twitter: https://twitter.com/TheScienceDAO
Deck: https://thesciencedao.io/files/deck.pdf
Discord: https://discord.gg/4pByE4Ft7r
GenomesDAO
GenomesDAO strives to meet the increasing expectations of research organizations, institutions as well as customers for the security of genomic data and the quality of research workflow. In order to increase the democratization and decentralization of genomic studies, they focus on combining cutting-edge technologies such as AMD’s SEV, blockchain and decentralized finance.
DAO docs: https://genomes.gitbook.io/genomes.io-docs/
Twitter: https://twitter.com/GenomesDAO
Discord - https://discord.com/invite/3DaD2na4XJ
Jocelynn’s notes: I haven’t been in their discord yet, but have heard them speak about the project. Seems DeFi focused.
Note from Alan Hyndman: I am involved in the GenomesDAO project, feel free to drop into the Discord to ask any questions.
LabDAO
The future of biomedical science is an open, community-run network of laboratories. CRO/Marketplace focus.
Twitter: https://twitter.com/lab_dao
Resources:
Arye & Niklas–Building a labDAO for web3 Biotech
Niklas Rindtorff–Graph Based Protocols
UltraRare podcast episode featuring LabDAO; also here.
Monthly updates: summary of what happened
PsyDAO
PsyDAO is a decentralised organisation with the goal of funding research at the intersection of psychedelics and mental health.
PsyDAO video
DeSciWorldDAO
DeSciWorld aims to connect the decentralised and scientific communities to help further the mission of Decentralising Science. The DAO coordinates treasury expenditure and future development goals. Working on a peer-to-peer marketplace for scientific bounties. Social hub that runs Friday Twitter Space called DeSci Rising.
Twitter: https://twitter.com/DeSciWorld
Discord: https://discord.gg/jnEUqVH8xv
Cerebrum DAO (previously CherubsDAO)
NFT funded, DAO governed collective investing in accelerating solutions & cures to Alzheimer’s disease and advancing brain wellness and longevity. 80% of funding dedicated to investments for ROI and impact, and 20% to fund primary research grants.
Twitter: https://twitter.com/Cerebrum_DAO
Discord: https://discord.com/invite/pSAbaHf7Rf
FrontierDAO
FrontierDAO is a Research and Development DAO for science and engineering that looks to incubate promising innovation in their focus areas of fusion energy, space exploration, and climate solutions. The end goal is to catalyze commercialization of the most promising technologies. They raise funds through membership and their NFT collection, available on OpenSea. Their NFT collections include IP-NFTs which are foundational to their scientific publishing platform, FrontierRegistry, which is an open publishing platform for scientists, academia, engineers and researchers who can opt to self-publish and choose to mint their research papers as NFTs. FrontierRegistry is a user-owned platform.
Discord: https://discord.com/invite/UQVVw8QWrV
Twitter: https://twitter.com/FrontierDAO
Research Collective
The Research Collective is a 501c(3) / DAO performing decentralized trials and ‘adversarial research’, often going against the status quo. It acts as a bridge between the ‘biohackers’ and crypto community.
Telegram: https://t.me/+hDgQ1cZ_jZQ3MDgx
ValleyDAO
Our vision is to support the transition to a sustainable bioeconomy by funding democratically elected academic research and collectively govern the generated IP.
Announcement article: valleydao.medium.com/5bc470a58482
Discord: discord.gg/APD46yZD7E
Twitter: twitter.com/valley_dao
HairDAO
HairDAO, a decentralized autonomous organization in search of a cure for hair loss. Hair loss remains one of the most pervasive medical conditions globally: 80% of men and 50% of women will experience noticeable hair loss in their lifetimes, with over 95% of cases caused by androgenic alopecia (male and female pattern baldness).
Website: https://www.hairdao.xyz/
Discord: https://discord.com/invite/nEKD4qBPSU
Twitter: https://twitter.com/HairDAO_
CureDAO
CureDAO is an alliance of digital health innovators working to minimize suffering in the universe by accelerating clinical discovery. This is done through a community-owned rewards collaboration over competition. The end result is the discovery of how millions of factors like foods, drugs, and supplements affect human health.
Website | Whitepaper | App | Studies | GitHub | Twitter | Discord
Antidote DAO
AntidoteDAO is an altruistic Web3 DAO Dedicated to Funding Various Cancer Initiatives started by Niko
Reputable DAO
Reputable DAO is a biohacking and personalized wellness community that allows members to sell their data to third parties over places like the Ocean marketplace.
Whitepaper: https://docs.reputable.health/product-docs/
Website: https://www.reputable.health/
Twitter: https://twitter.com/intent/follow?screen_name=reputabledao
Discord: https://discord.com/invite/bXaBCt4ueb
Future Foods DAO
Future Foods DAO is a community-owned collective funding early-stage alternative protein open-source research. We identify and fund the most promising foundational alternative protein research. We support early stage research and facilitate commercialization. Members can join Future Foods DAO by purchasing tokens or earning them through contributions of work or Intellectual Property.
Immortality
Immortality is a cryptocurrency designed to bring scientifically proven, peer reviewed age prevention and reversal into reality. Envisioning the treatment of aging in a world-class clinic using proven and novel therapies such as working with TensorFlow machine learning for prediction, improved diagnostics and imaging analysis, in vivo gene therapy, stem cells and in vivo partial reprogramming. Immortality's development team researches and works on three essential areas of longevity; lifestyle, pharmacology, and clinical. Contributing to peer-review and improve existing therapies and brainstorming novel therapies.
Homepage: https://imt.cx
Whitepaper: https://imt.cx/assets/pdf/whitepaper.pdf
Love Health
The Love DAO and Love Token represent the first decentralized approach to People-Powered Pharma™. Through the Love DAO, members of the community can submit clinical trial proposals, and share in the upside when treatments are launched. Our expert blockchain team has experience building unicorn startups and launching world-changing DAOs.
Documentation: https://trylove.wpengine.com/wp-content/uploads/2022/09/litepaper.pdf
Discord: https://discord.gg/love-dao
CrunchDAO is a Decentralized Autonomous Organization of scientists making use of collective intelligence to solve complex problems. Focusing on quantitative finance, it makes use of DeSci as a tool to coordinate its members.
DeSci domain: https://desci.crunchdao.com/
DeSci repository: https://github.com/crunchdao/desci-framework
Twitter: https://twitter.com/CrunchDAO
GenomicDAO is an AI-Powered DeSci platform using patent-pending technology to advance Precision Medicine for under-representative populations, such as Asians. We use AI technology to automate the process of analyzing peta-bytes of genomic data. At GenomicDAO, billions of individuals are entitled to more equitable and personalized healthcare solutions. Built by Genetica® - the Leading AI Biotech company in Asia, GenomicDAO can inherit from the three key pillars of technology, including AI Technology, Gene decoding Chip & Blockchain, to accelerate clinical studies comprehensively and ultimately develop precision medicine drugs.
Official Twitter: https://twitter.com/genomicdao
Whitepaper: https://docs.genomicdao.com/genomicdao-whitepaper/
Jocelyn DAO [l]
Jocelyn is the GOSH squared Open Science Collaborative for Scientists at Risk. Jocelyn DAO addresses some significant problems of modern science, offering free tools for research code reproducibility and safety, assessment of study design, improvement of research methodology, and recognition of commitments.
Website: https://jocelyn.gosh.sh/
Twitter: https://twitter.com/phs_dao
LinkedIn: https://www.linkedin.com/company/91598780
Telegram: https://t.me/desci_gosh
CannabisDAO
CANNABIS DAO is a decentralized autonomous organization that aims to support and develop the cannabis industry using decentralized science (DeSci) and blockchain technology. The project aims to fund and promote innovative cannabis research, build partnerships with key industry players, and create a transparent ecosystem where stakeholders can collaborate and share knowledge.
Website: https://cannabis-dao.xyz/
Docs: https://docs.cannabis-dao.xyz/
X (Twitter): https://twitter.com/CANN_DAO
Discord: https://discord.gg/qfrd2wtmmB
Telegram: https://t.me/+hYHJpANjigI4NWVl
Medium: https://medium.com/@cann_dao
Decentralized Science Ecosystems
We wanted to create a category for projects that are tackling multiple problems at once, such as decentralized financing of science and scientific publishing tools. These projects include multiple sectors but are not necessarily operating as DAOs.
Bio.xyz
A Molecule initiative funding decentralized science and biotech projects, and providing hands-on support from legal to tech. Funded VitaDAO, LabDAO, ValleyDAO, PsyDAO and more soon. Apply here for up to $100k: https://www.bio.xyz/.
QURE XR
QURE is an Extended Reality (XR) Scientist Content Creation Platform for DeSci Applications. QUREs tooling gamifies the standardization of research techniques & protocols - effectively enhancing scientist training & performance, attenuating the reproducibility crisis and enabling Decentralized Peer Review, at scale.
Core Team: Shar J. Qureshi, Eric Stone
Twitter: https://twitter.com/QURE_VR
DM for a demo!
Psi Combinator
A community that funds and accelerates the development of decentralized science projects.
Halogen
A platform/set of protocols aiming to replace the journal monopoly with a self-organizing network of self-sufficient scientific communities. Publishing, review, documentation, funding is all done at the community level. This model will solve the epistemic issues endemic to journal science and restructure the scientific epistemic engine to produce an accurate, representative, and usable knowledge base.
Whitepaper: Halogen- theoretical background
Website: https://halogen.cloud/
Point of contact: natashaaasmi@gmail.com or Twitter DM @AsmiNatasha
SCINET
SCINET is a decentralized life sciences ("DeSci") research and investment platform that revolutionizes the way people do and support science. Powered by blockchain technologies, SCINET allows retail and institutional investors to invest directly in life sciences research and technology with security and authenticity.
Core team: Jordan Smith, Hank Brigham
Linkedin: https://www.linkedin.com/company/scinet-us/ Tw: https://twitter.com/SCINET_INC
DeSci Foundation
We are an independent think tank of leading scientists and web3 pioneers, dedicated to exploring the potential of applying web3 technologies to the scientific ecosystem. Our mission is to support high-quality science by:
- Thinking carefully about the potential opportunities and risks of applying web3 technologies to the scientific ecosystem.
- Bringing scientists & web3 pioneers together.
- Supporting initiatives that have the potential to improve scientific progress.
- Creating new ways to finance and incentivize high-quality, replicable science.
Core team: Christopher Hill, Sina Iman, Philipp Koellinger, Erik Van Winkle
Twitter: https://twitter.com/DesciFoundation
Gridcoin
Gridcoin is a science-focused blockchain which uses minting protocols and fee-based mechanisms to incentivize computational contribution to distributed computing projects (on the BOINC network) working on various areas of scientific research, raise funds for research, and verify publication ownership.
Twitter: https://twitter.com/GridcoinNetwork
Discord: https://discord.gg/7EnbsJCWXD
The DeSci Academy
Onboarding non-technical users into science to create the next generation of scientists.
We find and train passionate, driven and curious individuals who want to contribute to science but lack the credentials.
Twitter: https://twitter.com/TheDesciAcademy
The Innovation Game
The golden era of hardware speedups is coming to an end. This has profound ramifications for our scientific & technological progress, as we are operating on a paradigm of solving increasingly complex computational problems. We predict the coming era will be one where there is immense value in improving the efficiency of foundational scientific algorithms, as they will determine which new scientific and technological advancements are tractable. Pre-empting this future, we are applying a framework of crypto-economics to address the market failure related to funding and transparency around the innovation of such algorithms. We call this framework The Innovation Game.
Litepaper: Link
Discord: https://discord.gg/YTJGVpZD
LabPredict
LabPredict is a prediction market designed to make longevity research interesting, collaborative, and reproducible.
deScier
deScier and The DeSci Journal aim to establish a decentralized scientific publication channel, challenging the current industry. The envisioned platform empowers scientists, scholars and entire communities to retain copyright, share knowledge, and benefit financially. We aim to change the way science is published.
Co-Led by: Maria Goreti Freitas (@goreti__freitas on Twitter) and Danilo Melo (@drdanilogestao on Twitter).
Websites: https://platform.desci.reviews
Twitter: https://twitter.com/@desciers
Discord: https://discord.gg/Z6U9P28YtV
Instagram: https://instagram.com/sci.dao?igshid=YmMyMTA2M2Y=
Telegram group: https://t.me/+KMddKMNNRwY0YTMx
IberoAm
IberoAm is a non-profit and three-fold initiative aiming to identify, promote and then support iberoamerican blockchain/web3 projects with a clear social and/or financial impact for the region and prioritizing minorities. By organizing Conferences, Hackathons and NFT Exhibitions as means to onboard then support the most impacting and innovative iberoamerican projects with a clear social/financial impact for the region and always prioritizing minorities.
Core team: Alberto Dávila, Rodrigo Jardim
Linktree: https://linktr.ee/iberoam
Telegram: https://t.me/+1OQV2dYwNAxjYTc5
Twitter: https://twitter.com/iberoam_xyz
Linkedin: https://www.linkedin.com/company/iberoam/
Instagram: https://instagram.com/iberoam.xyz
DeSci Africa
DeSci Africa is a non-profit aimed at supporting scientists in Africa through Decentralized Science. Through specialized meetups, travel grants, and events, among other things, the DeSci Africa community will raise awareness of decentralized science on the African continent. We aim to reroute funds toward research conducted by African scientists and laboratories while also creating channels of outreach and knowledge for those who are new to web3.
Core team: Daniel Anomfueme, Philip Ifeanyi, Nancy Amadi, Samuel Olamide.
Twitter: https://twitter.com/DeSciAfrica
Discord: https://discord.gg/4QyGdzknP8
Telegram: https://t.me/DeSciAfrica
LinkedIn: https://www.linkedin.com/company/desci-africa/
Website: https://desciafrica.xyz
AuraSci
AuraSci is committed to driving the decentralized science (DeSci) movement, merging humanistic spirit with scientific innovation. Our mission is to transform scientific research through blockchain technology, ensuring transparency, resistance to censorship, and collaborative exploration. As a self-governed collective, we unite scientists, thought leaders, and enthusiasts in advancing interdisciplinary collaborations and trust-minimized technology. Our long-term goal is to revolutionize scientific collaboration and creation by establishing a public network for DeSci, ensuring data integrity and accessibility. AuraSci aims to be a nexus between individuals and science, fostering an environment of openness and inclusivity. Join us in shaping a future where decentralized science bridges diverse perspectives and catalyzes innovation.
Twitter: https://twitter.com/Aura_Sci
Telegram: https://t.me/AuraSci1
Website: https://aurasci.xyz/
Resources for DAOs
Scientific Publishing
Teams, projects and companies trying to make improvements to how and where science gets published. Some of the themes include: incentivized peer review, micro-publications, and platforms where scientists can receive donations for their contributions.
ResearchHub
Our mission is to accelerate the pace of scientific research. ResearchHub provides an open forum where users can port in scientific publications, upload preprints through our notebook feature, generate scientific bounties and discuss science (like Reddit) incentivised by ResearchCoin. As an alternative to scientific journals, ResearchHub contains hubs of all genres of scientific research.
Discord: https://discord.gg/researchhub
ResearchHub Platform: https://www.researchhub.com/
Twitter: https://twitter.com/ResearchHub
Youtube: https://www.youtube.com/channel/UCU4kRS13JPo1hIPNV6eONmg
NobleBlocks
NobleBlocks is a blockchain-based platform that aims to address the challenges in academic publishing. It provides a decentralized space for researchers and scientists to collaborate, publish, and be equitably rewarded. With tokenized rewards and international scientific partnerships, NobleBlocks aims to make research more accessible and empower authors by focusing on the merit and impact of their work.
Twitter: https://twitter.com/nobleblocks
Telegram: https://t.me/nobleblocks
ScieNFT
ScieNFT is a platform that merges blockchain technology with scientific research, allowing researchers to transform their work into NFTs, fostering transparent ownership and enabling knowledge sharing.
Twitter: https://twitter.com/ScieNFT
Linkedin: https://www.linkedin.com/company/79413609/admin/feed/posts/
GitHub: https://github.com/ScieNFT/contracts
Longevity Review by VitaDAO
A platform that provides funding for researchers to review each other's work. It addresses critical issues with academic journals:
Website: https://longevity.review/about
Longevist by VitaDAO
Curating the world’s top longevity research. Preprints have revolutionized scientific publishing, allowing immediate sharing of discoveries. However, the overwhelming volume of preprints makes it difficult to keep up. The Longevist addresses this by spotlighting groundbreaking longevity studies each quarter. Using social listening, AI, and an expert network, they curate a shortlist. Longevist Curators vote to establish the top studies. The Longevist also provides a collaborative peer review platform, The Longevity Decentralised Review, integrating expert insights with user-friendly technology. Join the vibrant community, explore longevity science, and shape the future of the field.
Website: longevist.xyz
Atoms.org
Smart Contracts - https://atoms.org/scientiae#smart-research-contracts
Led by Darren. Many good essays here
Twitter: https://twitter.com/atoms_org/status/1409574011244204032
Ants Review
Incentivized peer reviews w/ @AntsReview (since April 2020)
Led by Bianca Trovò: https://twitter.com/bianca_troveaux
MVP: https://ants-review.on.fleek.co
Paper: https://link.springer.com/chapter/10.1007%2F978-3-030-71593-9_2
Abstract from paper linked above by Trovo and Massari
Discourse Graph
Flashpub.io
A platform for micro publications and articles
Led by Nate Jacobs - also active in the Blockchain for Science Telegram group
Link to Medium article
From the flashpub.io website - example of two kinds of publications
TalentDAO
sci2sci
sci2sci develops a “scientist-to-scientist” platform to conveniently store, share and search for research data. An electronic lab notebook conveniently paired with a publishing platform allows to easily release research data into open access - whenever it’s ready - in one click. Additionally, the search engine tailored specifically for datasets allows for advanced search options, such as finding datasets that contain the same information using search by structural similarity. It indexes data found both on the sci2sci platform and on external services such as Zenodo and FigShare.
LinkedIn: https://www.linkedin.com/company/sci2sci/
Twitter: https://twitter.com/sci2science
SciDex
Research Portfolio
Research Portfolio builds tools for researchers to mint and trade tokens representing their research output. We are creating a new funding model for scientists, journalists, historians, and anyone else adding to the collective search for truth. This model augments existing approaches. Used by $250k Amaranth Prize - rewarding the most impactful research in longevity.
Website: https://www.researchportfolio.co/
Publed is a decentralized scientific publishing platform that aims to address the challenges of the traditional and centralized publishing system by empowering researchers, liberating them from traditional gatekeepers, protecting their ownership, and enabling the monetization of their genuine work through crypto-economic incentives.
Twitter: https://twitter.com/publed_official
LinkedIn: https://www.linkedin.com/company/publ3d/
Landing Page: https://www.publed.io/
Articles & Podcasts on Scientific Publishing
UltraRare Podcast: Scientific Publishing is Broken. Can Web3 Fix It?
Episode featuring authors from two of the linked articles below (Ben Hills - Tokenized Thought, and Darren Zhu from Atoms.org): https://rss.com/podcasts/ultrarare/392814/
Tokenized Thought by @0xboodle:
Thread https://twitter.com/0xboodle/status/1457140825465364480
And full article
OpenAccessDAO’s Knowledge Resources
A collection of projects, articles, and media with links on scientific publishing https://docs.google.com/document/d/1nGX8Cc6xSWGZZa-SSNfRSel-b7z8qcgkqSStWsavsjE/edit
IP-NFTs
What exactly are IP-NFTs? I recommend watching the following video and reading Tyler Golato’s article linked below as a primer:
Video presentation: https://twitter.com/Molecule_to/status/1458455154382946306
IP-NFTs for Researchers: A New Biomedical Funding Paradigm by Tyler Golato
Molecule’s Biopharma IP-NFTs - A Technical Description by Clemens Ortlepp
IP/NFT Possibilities by Tristan Roberts
IP-Tokens
IP tokens (IPTs) are created from a parent IP-NFT. They are the natural next step in decentralizing drug development, allowing individuals to directly interact with, and govern the IP produced by world-class scientists.
https://www.molecule.to/products/iptokens
https://www.molecule.to/blog/molecule-launches-intellectual-property-tokens-ipts
https://www.molecule.to/blog/ipts-a-gain-of-function
Decentralized Biotech / Biopharma
A Guide to Decentralized Biotech
By Jocelynn Pearl, published in Future (a16z) 4-20-2022
Perlara PBC
Led by Ethan Perlstein
Perlara employs consultants that write work plans and perform project management for the development of therapies for families and nonprofit foundations seeking cures for rare diseases. It is a distributed biotech in the sense that it employs scientists around the world to work together to build ‘cure roadmaps’ for identifying new treatments for patients and foundations.
Vibe Bio
Led by Alok Tayi
Every patient with a life-altering disease — no matter how rare — should have a community and the power to pursue their cure. But too many patients with rare diseases feel abandoned because the treatments they need are considered too costly and too risky. Vibe Bio is building a DAO of patients, scientists, and partners to invent and invest in promising treatments for new medicines through alternative funding models. Our vision is for patients — not profits or politics — to drive drug discovery so that nobody will have to forge the path to a treatment alone.
Molecule
Led by Tyler Golato & Paul Kohlhaas
Molecule was inspired by the open science movement and open drug development that was happening in certain patient communities. The idea was to utilize blockchain tools to help advance and fund early stage drug development. To that end, the company has made several savvy decisions that have advanced the DeSci space, including ideating IP-NFTs, NFTs tied to intellectual property (think, a drug or research-based IP), and launching the VitaDAO community to fund longevity research. They continue to seed new DAOs and help advance the funding of early stage drug development. Their marketplace currently boasts around 60 research projects available for funding.
Visit the Molecule Discovery dapp
From https://discover.molecule.to/discover
Phage Directory
Learn more about Phage Directory in this UltraRare Podcast episode with the founders: https://rss.com/podcasts/ultrarare/452751/
Led by Jessica Sacher and Jan Zheng. Phage Directory was started from the observation that clinicians and scientists were seeking cures to antibiotic-resistant infections. Phage Directory was formed with a simple solution: building out a more concrete network of the people who might have the tools to help (in this case, phages). To date, the group has helped with three different cures. They continue to grow. Great model and simple template for decentralized cure discovery.
From the Phage Directory website.
Recerca - Tokenizing Research
Led by David Hunt, Dr. Sean Young, & Tyler Ruben. Recerca first got momentum after the team won 2nd prize in the Hedera X Filecoin Grant, for an application centered around solving data integrity problems, crowdfunding research, and NFT based participant rewards. So far the team has made great strides with its premier study completed in November 2021, and the user facing application that distributes participant NFT rewards is currently in closed alpha.
Crowd Funded Cures
Could a pay-for-success model bring certain off-patent treatments and repurposed generic drugs to the forefront and into patient hands without patents? That is the dream of Crowd Funded Cures, led by a team including Savva Kerdemelidis, Amir Amraie, Andrew Horton, Nick Fiorenza, Ariella Coler-Reilly, Zack West, & Spyridon Antonopoulos, Kash Nouroozi, Zan Lowe-Skilern, Dominic Nutt, Daniel Dohne.
Article explainer of the model
Blog: https://crowdfundedcures.org/blog/
Twitter: https://twitter.com/CrowdFundedCure
Facebook: https://www.facebook.com/crowdfundedcures/
Discord: https://discord.gg/6tFG8RDygW
LabDAO
The future of biomedical science is an open, community-run network of laboratories. CRO/Marketplace focus. LabDAO hopes to build an on-chain marketplace for wet and dry lab services to enable scientific progress. Prior to token launch, the team has already been hard at work on a command line interface for lab transactions that will have a test launch in early Q2 2022. Team is led by Niklas Rindtorff.
Twitter: https://twitter.com/lab_dao
Website: https://www.labdao.com/
Resources:
Arye & Niklas–Building a labDAO for web3 Biotech
Niklas Rindtorff–Graph Based Protocols
UltraRare podcast episode featuring LabDAO; also here.
CRO Directory Resource
Virtual Drug Development or Clinical Trial Platforms: coming soon
mRNA Swap for offsetting risk in clinical trial efficacy studies
Decentralized Space Exploration projects
LunCo
Permissionless collaborative space missions design tool powered by web3. With the help of LunCo it’s possible to run complex projects like planning civic CO2 tracking constellations, Lunar colony etc. Our mission is to make humanity multiplanetary species by providing a collaborative tool to plan missions together
Twitter: https://twitter.com/LunCoSim
Discord: https://discord.gg/p4KvvvG6
Gitcoin: https://gitcoin.co/grants/5939/lunco-full-cycle-space-operations-sim-tool
Giveth: https://giveth.io/project/lunco-a-full-cycle-space-operations-sim-tool
Github: https://github.com/LunCoSim/lunco-sim
Focused Research Organizations & Institutes
Foresight Institute
Convergent Research
Astera Institute
Arcadia Institute
New Science
Science NFTs
DNAverse
DNAverse is an NFT project collection customized with real DNA data. The long term mission is the geneticizing of avatars in the metaverse and the replication of life in the digital world with a self-sustainable decentralized model.
Twitter: https://twitter.com/Dnaverse_io
Discord: https://discord.gg/jxHBUghdnT
GeneNFT
GeneNFT is an experiment at the intersection of art, science, and technology.
UltraRare
UltraRare is a web3 collective exploring the intersection of art and science. Our team includes scientists, developers, and artists. We care about communicating science through audio and visual means, and we produce the UltraRare The Podcast to help onboard people to the web3 space.
AtomicHeartNFT
AtomicHeartNFT is a web3 collective showcasing images produced using electron microscopy and other advanced microscopy techniques.
Twitter: @atomicheartNFT
SameYou
SameYou is a charity raising money for treatments for brain injury or stroke. They auctioned an NFT as part of their campaign.
FrontierDAO
FrontierDAO is a science investment DAO with an art gallery as well - opensea.io/frontierdao
PLANT GANG
PLANT GANG is a community building the herbarium of the metaverse, producing scientific 3D model NFT plant specimens, with associated metadata and physical counterparts.
Twitter @PLANTGANGxyz
Discord: https://discord.gg/hfQhrFFnD4
Future Folklore
Decentralized Financing of Science and/or Philanthropy
BeakerDAO
BeakerDAO is a DAO, co-initiated by Tribute Labs that supports the expansion of decentralized science. Through research funding and IP management, the DAO aims to promote open accessibility & create decentralized market liquidity across the DeSci space.
Twitter: https://twitter.com/beakerdao
Medical.watch
We're building a medical knowledge base for the world. Imagine a medical version of Wikipedia + UpToDate, updated by doctors in real-time. With Medical.watch, doctors will have the latest medical knowledge to treat patients.
Twitter Spaces with DeSciWorld
Gitcoin
Gitcoin is a funding mechanism for web3 focused on public goods. Many of the DeSci projects in this Wiki are available for funding through Gitcoin, where your ‘dollars’ will be matched significantly (sometimes 4-60x!)
Gitcoin had its first DeSci funding round from 9/7-9/22, 2022.
“The GR15 Cause Rounds showcase projects using web3 to build & fund solutions related to 4 key social and environmental causes: Climate Solutions, Crypto Advocacy, DEI (Diversity Equity & Inclusion), and DeSci (Decentralized Science). Over $900k of matching funds is available for Cause Rounds so far!” -Gitcoin
Etica
Etica (Etica Protocol) is a blockchain whose goal is to finance Open Source medical research without intellectual property. Etica is a community driven project, there is no company nor private entity behind it. There are 2 cryptocurrencies on the Etica blockchain, ETI and EGAZ. ETI is what makes the Etica open source research system work and rewards researchers. EGAZ secures the Etica blockchain, it is the equivalent of ETC and ETH on Ethereum blockchain.
- Github: https://www.github.com/etica
- Presentation website: https://www.eticaprotocol.org
- Explorer: https://www.eticascan.org
- Network Metrics: https://www.eticanomics.net
- ETI mining pools: https://www.eticapool.com/pools
- EGAZ mining pools: https://miningpoolstats.stream/etica
- Tutorials: https://www.eticaprotocol.org/eticadocs
- A Web3 app running on top of Etica example: https://www.etica.io/
- Discord: https://discord.gg/CrTKpETKXc
- Twitter: https://twitter.com/eticaprotocol
- Telegram: https://t.me/eticaprotocol
Experiment
The first crowdfunding platform for science.
Launched in 2012 by Cindy Wu and Denny Luan.
UltraRare’s Podcast episode with David Lang covers crowdfunding platforms for science (and DeSci): https://rss.com/podcasts/ultrarare/476700/
Experiment Patron NFTs: https://opensea.io/collection/experimentpatrons
Crowd Funded Cures (see above)
@CrowdFundedCure
Giveth.io
Science Fund
An initiative to create funding pools for Science through NFTs
Sesame Foundation
For science enthusiasts and philanthropists who want to support research in computational mathematics, the Sesame Foundation provides a platform for creating and contributing to decentralized prizes. Unlike other research funding platforms, Sesame Prizes use smart contracts to ensure that prizes are awarded only once a given problem is actually solved.
GainForest / LabDAO Rainforest Monitoring Lab
The rainforest monitoring lab is bringing together young engineers, students and scientists to contribute to an open and reproducible machine learning repository for rainforest monitoring. The models will then be used to transparently analyze carbon offset projects around the world and assess nature’s contribution for ReFi. We encourage applicants from traditionally underrepresented communities to apply. LabDAO and GainForest team members will guide all stipend recipients during their research journey. Recipients will receive impact certificates as POAP. Additionally, developed machine learning models have a chance to contribute to GainForest’s $10M XPRIZE Rainforest participation.
Science program: https://beta.gainforest.app/science
Main website: http://gainforest.earth/
ViralCure
We are an impact-first Decentralized Science platform that helps fund healthcare-oriented research and development in alternative ways. Part of the Sthorm Web3 project ecosystem with a long trajectory working with alt-funding for scientific projects.
Twitter: https://mobile.twitter.com/viral_cure
Discord: https://discord.gg/Wv4EQHPuT7
Atom
Atom aims to accelerate scientific research by revolutionizing today’s funding mechanisms for basic research. The current system of funding research is often biased, opaque, and inefficient with regards to allocating funds. Atom is building the financial infrastructure for science starting with a platform utilizing quadratic funding and other blockchain powered models to identify and fund the most impactful early stage research projects.
Data Storage & Blockchain Protocols
DeSci Labs
DeSci Labs is building the infrastructure for Decentralized Science. DeSci Nodes, the first product from DeSci Labs enables a radically transparent ledger of scientific record that is secure, permanent, interoperable and resistant to cross-national censorship.
Watch the product demo or join the discord to learn more
Twitter: https://twitter.com/DeSciLabs
Fleming Protocol
A data economy where patients capture the value of their data. Through incentivization & innovative data monetization mechanisms, we enable patients & biomedical innovators to collaborate & create value in a privacy preserving way.
OceanProtocol
Tools for the web3 data economy
Data owners and consumers use Ocean Market app to publish, discover, and consume data in a secure, privacy-preserving fashion. OCEAN holders stake liquidity to data pools. Developers use Ocean libraries to build their own data wallets, data marketplaces, and more. Ocean datatokens wrap data services as industry-standard ERC20 tokens. This enables data wallets, data exchanges, and data co-ops by leveraging crypto wallets, exchanges, and other decentralized finance (DeFi) tools.
Bacalhau
The goal of our project is to give researchers and data engineers the ability to publicly reproduce data pipelines, thereby making their research more transparent and reusable. Please see our project page here for more detail:
https://github.com/filecoin-project/bacalhau
Weavechain
Weavechain offers a solution for both public and private datasets, with immutable blockchain properties guaranteeing data lineage and advanced role-based permissioning to the table level guaranteeing security. Researchers can share and access secure and tamper-proof data instantly, without any need to download updates, since additions are reflected in real-time.
Ceramic
Ceramic is a decentralized network where people can collaborate on open data sets while being in control over their data. ComposeDB is a graph database built on top of Ceramic that enables developers to create public knowledge graphs, social applications, DAO coordination tooling, etc. Ceramic works with most existing web3 wallets and enables a seamless experience for users interacting with data in the system.
Kamu
Kamu is a decentralized data supply network created to address the ongoing reproducibility crisis in science. Think of it as "Git for Data" that lets you easily share both static and highly dynamic data without losing ownership, collaborate with others on building data processing pipelines that continuously clean, combine, and enrich data from other sources, and effortlessly maintain 100% reproducibility, verifiability, and detailed provenance of data for your analysis and ML projects.
To learn more: https://docs.kamu.dev/cli/
Join our Discord and visit our Github!
DB DAO
DB DAO is a drop-in replacement for Postgres/Mongo for web3 apps. Open source. Every database is managed by DAO/multisig/Gnosis Safe. All rows in a database are NFTs. If configured by the DAO, rows are eligible for rewards if they are accepted into the database. Queries to the database will soon be verified with ZK proofs. White label app available on GitHub to fork and get started building your app. Focused on the DeSci and open source space.
Twitter: https://twitter.com/db_dao
Abakhus
Abakhus is a set of decentralized and interconnected privacy-preserving Health and Life Sciences data and services that leverage the full capabilities of Private Smart Contracts on Secret Network and IBC from the Cosmos Ecosystem. By making extensive use of private metadata, Abakhus is the world's first protocol to bring together in one place (a) clinical/veterinary laboratory specialists, (b) multi-omics, bioinformatics and systems biology
specialists, (c) software developers in the health and life sciences space, (d) physicians
and veterinarians and (e) end-users in need of clinical/veterinary/multiomics/systems biology services. Abakhus offers privacy-preserving services to clinical/veterinary laboratories, data analysis companies and end-users wishing to (i) tokenize medical/veterinary records, (ii) tokenize clinical/veterinary laboratory services, (iii) offer tokenized multi-omics or systems
biology data analysis, (iv) offer tokenized code/software and (v) offer tokenized curated databases.
Core team: Alberto Dávila, Rodrigo Jardim
Linktree: https://linktr.ee/abakhus
Twitter: https://twitter.com/abakhus
Data Lake
Data Lake is an EU-funded start-up creating a global medical data donation system, based on web3 technologies. Just like donating blood, people can donate their medical records to researchers around the globe who need medical data to cure diseases, develop new treatments, and improve diagnostics and patient outcomes. Consents are recorded on the Polygon blockchain, which ensures researchers have a guarantee that they have a legal right to access the donor’s data. The entire process respects patient privacy, and consent can be revoked at any time. To incentivize stakeholder participation, the project is tokenized and uses the $LAKE token to reward data donors, as well as other market participants.
To learn more: https://data-lake.co
Social channels: https://data-lake.co/social/
Press & Collaborations: dinidh.obrien@data-lake.co
Data Management & Valorisation
DataUnion[m]
Articles / Misc. Resources
Feel free to suggest new categories as trends appear.
With cryptocurrency and NFTs, ‘decentralized science’ seeks to upend drug industry financing.
Stat News article by Allison DeAngelis - June 23, 2022
Molecule Fundraising Announcement
Decentralized science platform Molecule raises $13 million in seed funding
By Tom Matsuda - June 13, 2022
A Guide to DeSci
By Sarah Hamburg published in Future (a16z)
Retroactive Public Goods Funding
How to DAO with People, not just Protocols
By Mike McCoy
How to organize, make decisions, structure and allocate wealth in DAOs
Science and Web3: Do non-fungible tokens (NFTs) provide a way to democratise and increase scientific funding?[n]
By Adrian Stencel
Article on democratizing science through web3
Non fungible tokens (NFTs) for academic publications?
By David Greshan
How scientists are embracing NFTs
Nature Article
IBFS (Blockchain for Science) First Announcement
Epoch 16 - Decentralized Science - DeSci
By BowTiedBiotech
DeSci: Can Crypto Improve Scientific Research?
By Max Parasol
A DeSci Origin Story
by Dr. David Koepsell
DeSci: How Can DAOs Facilitate Collaboration And Push The Open Science Movement Forward
By Eliot Couvat (Coinvise)
The New Web 3 Movement to Revolutionize Scientific Research and Funding
By Sergey Baloyan - May 3, 2022
How do Decentralized Science Organizations Work
By Maria Isabella - Feb 25 2022
The Rise of DeSci Blockchain and the Future of Research
By AIBC - May 30, 2022
Why Science? Why Blockchain? Why DAO Now?
By Paige Donner - Dec 26, 2021
Trustless Science
By Jonathan Starr - May 9 2022
DeSci-Web3 Twitter List
By Jocelynn Pearl
DeSci-Web3 Twitter List
DeSci Social Communities
IRL communities
- New York: http://desci.nyc
Discord communities
- VitaDAO discord: https://discord.gg/invite/vitadao
- LabDAO discord https://discord.com/invite/labdao
- Molecule discord: https://discord.com/invite/uAGW7K4hQU
- Crowd Funded Cures discord: https://discord.gg/6tFG8RDygW
- DeSciAlliance: https://discord.com/invite/D2DxBpkfWZ
- DeSci Labs discord: https://discord.gg/s5tJFwCYvK
- DeSciWorld discord: https://discord.gg/KchqF35uKm
- Web3 Women in Science discord: https://discord.gg/X3cx5zer
- DeSci Africa: https://discord.gg/4QyGdzknP8
Telegram communities
- Blockchain for Science: https://t.me/BlockchainForScience
- Open Science Ecosystem: https://t.me/osftw
- Research Collective: https://t.me/joinchat/PDmTa9ByTy44MDIx
- Design Thinking / UX in DeSci (reach out to @danielyse_ on Twitter)
- DeSci Africa: https://t.me/DeSciAfrica
- Bankless DeSci: https://t.me/BanklessDeSci
- DeSci Asia: https://t.me/DeSciAsia
- AuraSci: https://t.me/AuraSci1
- DeSci Youths (needs more info - Dani reached out to Victor)
Book Recommendations
Working in Public by Nadia Eghbal
Reinventing Discovery by Michael Nielsen
Reinventing Organizations by Frederic Laloux
Impact Networks by David Ehrlichman
Archived Projects
OpenAccessDAO
Making science open access for all.
Twitter: https://twitter.com/OpenAccessDAO
Discord: https://discord.gg/qQWeRAXg
Jocelynn notes: server now dead.
Agora Labs
A platform where scientific publications and their researchers can be ‘invested in’. Actually building out the platform - expected to release ~ September 1
Website: https://www.agora-labs.com/
LinkedIn: https://www.linkedin.com/company/agoralabscom/about/
Framework Bio
Founder: Patrick Thayer
Twitter: https://twitter.com/frameworkbio
Dani notes: Project on hold while team is focused on continuing education
Impact Finance
Impact Finance builds web3 tools with the aim of increasing the impact that citizen scientists can have on the scientific research process and the development of new technologies. We’re building a community-governed platform that enables science-based digital asset creators to cultivate their professional networks, track reputation, fund research, and unlock new opportunities for collaboration and cooperation.
BioDAO
BioDAO aims to be a collective funding DAO for biotech startups and drug discovery. Led by Rushi Trivedi and Alex Pustov. Discord community is still somewhat small. Project has been going on for 7+ months and the team has chosen to build mostly with core team and not community involvement. Similar to Molecule, the goal is to own biotech assets developed by DAO-funded projects.
Twitter: https://twitter.com/biodaoxyz
Discord: https://discord.com/invite/7yMtZwp7Rq
From https://www.biodao.xyz/#solution
CRISPR DAO
CRISPR DAO is building a decentralized organization to fund cutting edge CRISPR research to advance potential therapies and Ag-tech solutions.
Join the Discord: https://discord.com/invite/NWGqnU6Zjt
Led by Nat Harooni: https://twitter.com/NatHarooni
Dani notes: Twitter and Discord has been inactive for >1year
DeSci Nerdery
Discord: https://discord.gg/R3pjhntRDj (not company affiliated)
DeBio Network
DeBio eliminates risks of genetic discrimination by leveraging blockchain technology and high-level encryption to protect identity — while allowing users to access the benefits of genetic testing
Whitepaper here
DeBio discord: https://discord.com/invite/J2nWEB4Vn2
Try it out on Testnet or run on Mainnet
DeNature DAO
We are a decentralized science DAO that aims to empower STEM innovators using blockchain technology.
Dani note: Group has disassembled and is no longer active (contacted Sam Nehme who was a founder)
NeuraDAO
NeuraDAO is a community-governed, decentralized platform for neurotech research and intellectual property.
Twitter: https://twitter.com/neuradao
Website: https://neuradao.co/
Discord: https://discord.com/invite/HnMQsGP8jB
LYNX
Planck
Manuscripts as NFTs by Matthew Stephenson https://www.p1anck.com/
Hasn’t been a lot of activity recently as of 05/2022
Interview with Matt on The Unstoppable Podcast
Interview with Matt on SciBetter
Dani notes: Dani notes: No new activity for a while; doesn’t seem active.
OpenNMN
OpenNMN is a DAO formed to make the supplement NMN accessible with community based biotech
Dani notes: No new activity for a while; doesn’t seem active.
Moon Rabbit
Moon Rabbit is a distributed crypto-conglomerate — 安居財閥 (AngoZaibatsu) — constituting a system of systems (Jurisdictions), uniting all distributed ledgers and cryptocurrencies in the ultimate cross-chain protocol – a Metachain. Moon Rabbit is focused on building scalable incentive models and web3 infrastructure to accelerate Longevity R&D. We are constantly integrating new chains and recently partnered with the world's leading Longevity research institution, Foresight Institute.
Dani notes: No new activity for a while; doesn’t seem active.
[a]DeSci Asia already update their new logo. Pls kindly help to renew in the figma. Thanks a lot. https://pbs.twimg.com/profile_images/1708558852587700224/c-cU9NML.jpg
[b]谢谢
[c]_Marked as resolved_
[d]_Re-opened_
謝謝
[e]DeSci Asia update its logo
[f]Thank you! We will update on the next iteration.
[g]Thanks for your kind help
[h]_Marked as resolved_
[i]_Re-opened_
Thanks
[j]DeSci Mexico
[k]has been sunset
[l]I believe also sunset
[m]@jocelynn.pearl@gmail.com this might be more appropriate under open science?
[n]410 The author deleted this Medium story.