Papers, Chapters and Textbooks

Papers (alphabetical, by student’s last name)

Karmur BS, Philteos J, Abbasian A, Zacharia BE, Lipsman N, Levin V, Grossman S, Mansouri A. Blood-Brain Barrier Disruption in Neuro-Oncology: Strategies, Failures, and Challenges to Overcome. Front Oncol. 2020 Sep 18;10:563840. doi: 10.3389/fonc.2020.563840. PMID: 33072591; PMCID: PMC7531249.

Ziegler T, Adibfar A, Abbasian A, Jiang SX, Rutka JT, Gawad N. Propagating the “SEAD”: Exploring the value of an overnight call shift in the Surgical Exploration and Discovery (SEAD) program. Journal of Surgical Education. 2019. doi: 10.1016/j.jsurg.2019.08.011

Mansouri A, Taslimi S, Abbasian A, Badhiwala JH, Akbar MA, Alotaibi NM, Almenawar SA, Weil AG, Fallah A, Carmant L, & Ibrahim, G. M. Surgical outcomes for medically intractable epilepsy in low- and middle-income countries: a systematic review and meta-analysis. Journal of Neurosurgery. 2018. doi: 10.3171/2018.5.JNS18599.

Mansouri, A., Ku, J. C., Khu, K. J., Mahmud, M. R., Sedney, C., Ammar, A., Godoy, B. L., Abbasian, A., & Bernstein, M. Exploratory Analysis into Reasonable Timeframes for the Provision of Neurosurgical Care in Low- and Middle-Income Countries. World Neurosurgery, 2018. doi: 10.1016/j.wneu.2018.06.111

Artusa P, Nguyen Yamamoto L, Barbier C, Valbon SF, Aghzadeh Habashi Y, Djambazian H, Ismailova A, Lebel ME, Salehi-Tabar R, Ragoussis J, Goltzman D, Melichar HJ & White JH. (2024). Skewed epithelial cell differentiation and premature aging of the thymus in the absence of vitamin D signaling. Science Advances, 10(39). doi: 10.1126/sciadv.adm9582

Ringuette, R., Atkins, M., Lagali, P. S., Bassett, E. A., Campbell, C., Mazerolle, C., Mears, A. J., Picketts, D. J., and Wallace, V. A. (2016) A Notch-Gli2 axis sustains Hedgehog responsiveness of late neural progenitors and Müller glia. Dev. Biol. 411, 85-100.

Ringuette, R., Wang, Y., Atkins, M., Mears, A. J., Yan, K., and Wallace, V. A. (2014) Combinatorial Hedgehog and mitogen signaling promotes the in vitro expansion but not retinal differentiation potential of retinal progenitor cells. Invest. Ophthalmol. Vis. Sci. 55, 43-54.

Atkins, M.H., Scarfò, R., McGrath, K.E., Yang, D., Palis, J., Ditadi, A., Keller, G.M. (2022) Modeling human yolk sac hematopoiesis with pluripotent stem cells. J Exp Med. 219(3):e20211924. doi: 10.1084/jem.20211924. PMID: 34928315,

Tam DY, Azizi PM, Fremes SE, Chikwe J, Gaudino M, Wijeysundera HC. The cost-effectiveness of transcatheter aortic valve replacement in low surgical risk patients with severe aortic stenosis. Eur Heart J Qual Care Clin Outcomes. 2020 Jul 9:qcaa058. doi: 10.1093/ehjqcco/qcaa058. Epub ahead of print. PMID: 32645146.

Behrouzi, B., Sivaswamy, AS., Chu, A., Ferreira-Legere, LE., Abdel-Qadir, H., Atzema, CL., Jackevicius, C., Kapral, MK., Wijeysundera, HC., Farkouh, ME., Ross, HJ., Ha, ACT., Tadrous, M., Paterson, M., Gershon, AS., Dzavik, V., Fang, J., Kaul, P., van Diepen, S., Goodman, SG., Ezekowitz, JA., Bainey, KR., Ko, DT., Austin, PC., McAlister, FA., Lee, DS., Udell, JA. Sex-Based Differences in Severe Outcomes, Including Cardiovascular Hospitalization, in Adults with COVID-19 in Ontario, Canada. JACC Advances. (2023). doi: 10.1016/j.jacadv.2023.100307

Behrouzi, B., Udell, JA. A Nudge a Day Keeps the Influenza Away. Circulation. (2023). doi: 10.1161/CIRCULATIONAHA.123.064456

Udell, JA., Behrouzi, B., et al. Clinical Risk, Sociodemographic Factors, and SARS-CoV-2 Infection Over Time in Ontario, Canada. Scientific Reports. (2022) doi: 10.1038/s41598-022-13598-z

Behrouzi, B., Bhatt, DL., Cannon, CP., Vardeny, O., Lee, DS., Solomon, SD., Udell, JA. Association of Influenza Vaccination With Cardiovascular Risk: A Meta-analysis. JAMA Network Open. (2022). doi: 10.1001/jamanetworkopen.2022.8873

Behrouzi, B., Udell, JA. Universal Flu Vaccines: A Shot at Lifelong Cardioprotection? Nature Reviews Cardiology. (2022) doi: 10.1038/s41569-021-00670-w

Behrouzi, B., Udell, JA. Moving the Needle on Atherosclerotic Cardiovascular Disease and Heart Failure with Influenza Vaccination. Current Atherosclerosis Reports. (2021) doi: 10.1007/s11883-021-00973-w

Udell, JA., Behrouzi, B., et al. Clinical Risk, Sociodemographic Factors, and SARS-CoV-2 Infection Over Time in Ontario, Canada. medRxiv Prepr. (2021) doi: https://doi.org/10.1101/2021.04.28.21256.

Behrouzi B, Araujo Campoverde MV, Liang K, Talbot HK, Bogoch II, McGeer A, Fröbert O, Loeb M, Vardeny O, Solomon SD, Udell JA. Influenza Vaccination to Reduce Cardiovascular Morbidity and Mortality in Patients With COVID-19: JACC State-of-the-Art Review. J Am Coll Cardiol. 2020 Oct 13;76(15):1777-1794. doi: 10.1016/j.jacc.2020.08.028. PMID: 33032740; PMCID: PMC7535809.

Behrouzi, B. & Udell, JA. Influenza vaccine as part of a heart disease armamentarium in the Ohnew cardio-respiratory virus era. Trends Cardiovasc. Med. (2020) doi:10.1016/j.tcm.2020.07.001.

Kenigsberg, S., Wyse, BA., Behrouzi, B., Azizeddin, A., Librach, CL., da Silveira, JC. Protocol for Exosome Isolation from Small Volume of Ovarian Follicular Fluid: Evaluation of Ultracentrifugation and Commercial Kits. Methods Mol. Biol. (2017). doi: 10.1007/978-1-4939-7253-1_26.

Behrouzi, B., Kenigsberg, S., Alladin, N., Swanson, S., Zicherman, J., Hong, SH., Moskovtsev, SI., Librach, CL. Evaluation of potential protein biomarkers in patients with high sperm DNA damage. Syst Biol Reprod Med. 2013 Jun;59(3):153-63. doi: 10.3109/19396368.2013.775396.

Holborn J., Walczyk-Mooradally A., Perrin C., Alural B., Aitchison C., Borenstein A., Jones N., Khokhar J.Y., Akhtar T.A., Lalonde J. Interference of neuronal TrkB signaling by the cannabis-derived flavonoids cannflavins A and B. Phytomedicine Plus. 2023 Feb;3(1). doi: 10.1016/j.phyplu.2023.100410.

Singh R.P., Jeyaraju D.V., Voisin V., Hurren R., Xu C., Hawley J.R., Barghout S.H., Khan D.H., Gronda M., Wang X., Jitkova Y., Sharon D., Liyanagae S., MacLean N., Seneviratene A.K., Mirali S., Borenstein A., Thomas G.E., Soriano J., Orouji E., Minden M.D., Arruda A., Chan S.M., Bader G.D., Lupien M., Schimmer A.D. Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal. Cell Stem Cell. 2020 Jun 4;26(6):926-937.e10. doi: 10.1016/j.stem.2020.04.010.

Wu RY, Botts SR, Johnson-Henry KC, Landberg E, Abrahamsson TR, Sherman PM. Variations in the Composition of Human Milk Oligosaccharides Correlates with Effects on Both the Intestinal Epithelial Barrier and Host Inflammation: A Pilot Study. Nutrients. 2022; 14:1014. doi: 10.3390/nu14051014

Li B, Lee C, Cadete M, O’Connell JS, Alganabi M, Lee D, Ganji N, Miyake H, Botts SR, Johnson-Henry KC, Määttänen P, Sherman PM, Pierro A. Amniotic fluid stem cell administration can prevent epithelial injury from necrotizing enterocolitis. Pediatric Research. 2022; 91:101-106. doi: 10.1038/s41390-021-01657-6

Botts SR, Fish JE, Howe KL. Dysfunctional Vascular Endothelium as a Driver of Atherosclerosis: Emerging Insights into Pathogenesis and Treatment. Frontiers in Pharmacology. 2021; 12:787541. doi: 10.3389/fphar.2021.787541

Botts SR, Rossi L, Surette MG, Qadura M, Andrinopoulos T, Howe KL, Harlock J. Peripheral Artery Disease Patients With Chronic Limb-Threatening Ischemia Show Altered Blood Microbiota Composition Compared With Intermittent Claudication. Journal of Vascular Surgery. 2020; 72: e348. doi: 10.1016/j.jvs.2020.08.053

Li B, Lee C, O’Connell J, Antounians L, Ganji N, Alganabi M, Cadete M, Nascimben F, Koike Y, Hock A, Botts SR, Wu RY, Miyake H, Minich A, Maalouf MF, Zani-Ruttenstock E, Chen Y, Johnson-Henry KC, De Coppi P, Eaton S, Määttänen P, Delgado-Olguin P, Zani A, Sherman PM, Pierro A. Activation of Wnt signaling by amniotic fluid stem cell-derived extracellular vesicles attenuates intestinal injury in experimental necrotizing enterocolitis. Cell Death & Disease. 2020; 11:750. doi: 10.1038/s41419-020-02964-2

Botts SR, Rossi L, Surette MG, Qadura M, Andrinopoulos T, Howe KL, Fox-Robichaud A, Harlock J. Peripheral Artery Disease Patients with Chronic Limb-Threatening Ischemia Show Altered Blood Microbiota Composition as Compared with Intermittent Claudication. Journal of Vascular Surgery. 2020; 72: e212. doi: 10.1016/j.jvs.2020.04.359

Lurz E, Horne RG, Määttänen P, Wu RY, Botts SR, Li B, Rossi L, Johnson-Henry KC, Pierro A, Surette MG, Sherman PM. Vitamin B12 Deficiency Alters the Gut Microbiota in a Murine Model of Colitis. Frontiers in Nutrition. 2020; 7:83. doi: 10.3389/fnut.2020.00083

Määttänen P, Lurz E, Botts SR, Wu RY, Robinson SC, Yeung CW, Colas R, Li B, Johnson-Henry KC, Surette ME, Dalli J, Sherman PM. Plant‐ and Fish‐Derived n‐3 PUFAs Suppress Citrobacter Rodentium-Induced Colonic Inflammation. Molecular Nutrition & Food Research. 2020; 64:1900873. doi: 10.1002/mnfr.201900873

Li B, Lee C, Cadete M, Zhu H, Koike Y, Hock A, Wu RY, Botts SR, Minich A, Alganabi M, Chi L, Zani-Ruttenstock E, Miyake H, Chen Y, Mutanen A, Ngan B, Johnson-Henry KC, De Coppi P, Eaton S, Määttänen P, Delgado Olguin P, Sherman PM, Zani A, Pierro A. Impaired Wnt/β-catenin pathway leads to dysfunction of intestinal regeneration during necrotizing enterocolitis. Cell Death & Disease. 2019; 10:743. doi: 10.1038/s41419-019-1987-1

Wu RY, Li B, Koike Y, Määttänen P, Miyake H, Cadete M, Johnson-Henry KC, Botts SR, Lee C, Abrahamsson TR, Landberg E, Pierro A, Sherman PM. Human Milk Oligosaccharides Increase Mucin Expression in Experimental Necrotizing Enterocolitis. Molecular Nutrition & Food Research. 2019; 63:1800658. doi: 10.1002/mnfr.201800658

Mohiuddin MM, Botts SR, Paschos A, Schellhorn HE. Temporal and spatial changes in bacterial diversity in mixed use watersheds of the Great Lakes region. Journal of Great Lakes Research. 2019; 45:109-118. doi: 10.1016/j.jglr.2018.10.007

Li B, Hock A, Wu RY, Minich A, Botts SR, Lee C, Antounians L, Miyake H, Koike Y, Chen Y, Zani A, Sherman PM, Pierro A. Bovine milk-derived exosomes enhance goblet cell activity and prevent the development of experimental necrotizing enterocolitis. PLOS One. 2019; 14:e0211431. doi: 10.1371/journal.pone.0211431

Määttänen P, Lurz E, Botts SR, Wu RY, Yeung CW, Li B, Abiff S, Johnson-Henry KC, Lepp D, Power KA, Pierro A, Surette ME, Sherman PM. Ground flaxseed reverses protection of a reduced fat diet against Citrobacter rodentium-induced colitis. American Journal of Physiology-Gastrointestinal and Liver Physiology. 2018; 315:G788-G798. doi: 10.1152/ajpgi.00101.2018

Wu RY, Määttänen P, Napper S, Scruten E, Li B, Koike Y, Johnson-Henry KC, Pierro A, Rossi L, Botts SR, Surette MG, Sherman PM. Non-digestible oligosaccharides directly regulate host kinome to modulate host inflammatory responses without alterations in the gut microbiota. Microbiome. 2017; 5:135. doi: 10.1186/s40168-017-0357-4

D’Cruz R, Kyo-Kim Y, Mulder J, Ibeh N, Jiang N, Tian Y, Rosenblum ND. (2023) Hedgehog signaling in Foxd1+ embryonic kidney stromal progenitors controls nephron formation via Cxcl12 and Wnt5a. Journal of Pathology. 261 (4), 385-400.

Greenberg D, D’Cruz R, Lacanlale JL, Rowan CJ, Rosenblum ND. (2023) Hedgehog-GLI mediated control of renal formation and malformation. Frontier Nephrol 20;3:1176347.

Brunet J, D’Cruz R, Skelly M, Solish M, Srivastava A. (2021) Supplementary Issue: Medical Student Research Day. UTMJ 98, 1.1

Mulder J, Sharmin S, Chow T, de Carvalho Rodrigues D, Hildebrandt M, D’Cruz R, Rogers I, Ellis J, Rosenblum ND. (2020). Generation of infant- and pediatric-derived urinary induced pluripotent stem cells competent to form kidney organoids. Pediatr Res 87(4), 647–655.

D’Cruz R, and Stronks K, Rowan CJ, Rosenblum ND. (2020). Lineage-specific roles of hedgehog-GLI signaling during mammalian kidney development. Pediatr Nephrol 35(5), 725–731.

Gravely A, Vlasov A, Freeman A, Wu K, Szewczyk NJ, D’Cruz R, Batt J. (2018). Levels of Acid Sphingomyelinase (ASM) in Caenorhabdittis elegans in microgravity. Journal of the American Society for Gravitational and Space Research. 6(1):27-36

D’Cruz R, and Plant PJ, Pablo LA, Lin S, Chackowicz J, Correa J, Bain J, Batt J. (2016). PDLIM7 is a novel target of the ubiquitin ligase Nedd4-1 in skeletal muscle. Biochem J. 1;473(3):267-76

Park, L. J., D'Souza, D., Kazi, T., Rodriguez, F., Griffiths, C., McKechnie, T., ... & Serrano, P. E. (2024). Comparing cefazolin/m etronidazole, p iperacillin‐tazobactam, or c e foxitin as surgical antibiotic prophylaxis in patients undergoing pancreaticoduodenectomy: A retrospective cohort study. Journal of Surgical Oncology, 129(8), 1413-1419.

Griffiths, C. D., D'Souza, D., Rodriguez, F., Park, L. J., & Serrano, P. E. (2024). Quality of life following perioperative optimization with nutritional supplements in patients undergoing gastrointestinal surgery for cancer: A randomized, placebo‐controlled feasibility clinical trial. Journal of Surgical Oncology, 129(7), 1289-1294.

Berardi, G., Cucchetti, A., Sposito, C., Ratti, F., Nebbia, M., D’Souza, D. M., ... & Mazzaferro, V. (2024). Recurrence and tumor-related death after resection of hepatocellular carcinoma in patients with metabolic syndrome. JHEP Reports, 6(7), 101075.

D’Souza, D., Empringham, J., Pechlivanoglou, P., Uleryk, E. M., Cohen, E., & Shulman, R. (2023). Incidence of diabetes in children and adolescents during the COVID-19 pandemic: a systematic review and meta-analysis. JAMA network open, 6(6), e2321281-e2321281.

Gudmundsdottir, H., Fiorentini, G., Essaji, Y., D’Souza, D., Torres-Ruiz, T., Geller, D. A., ... & AMILES Group Bourdeau Thimoty Chung Christine Conn Deborah Martinie John Paterakos Pierce Ruo Leyo Tohme Samer Vrochides Dionisios Wang Jaeyun. (2023). Circumstances and implications of conversion from minimally invasive to open liver resection: a multi-center analysis from the AMILES registry. Surgical Endoscopy, 37(12), 9201-9207.

Berardi, G., Ratti, F., Sposito, C., Nebbia, M., D’Souza, D. M., Pascual, F., ... & Kingham, T. P. (2023). Model to predict major complications following liver resection for HCC in patients with metabolic syndrome. Hepatology, 77(5), 1527-1539.

Zou, P., D'Souza, D., Luo, Y., Sun, W., Zhang, H., & Yang, Y. (2022). Potential effects of virtual interventions for menopause management: a systematic review. Menopause, 29(9), 1101-1117.

Dent, A., Faust, K., Lam, KH B., Ahangari, N., Leon, A., Tsang, Q., Kamil, Z., Gao, A., Pal, P., Lheureux, S., Oza, A., & Diamandis, P. (2023) HAVOC: Small-scale histomic mapping of biodiversity across entire tumor specimens using deep neural networks. Science Advances. 9.

Dent, A. & Diamandis, P. (2022) Integrating computational pathology and proteomics to address tumor heterogeneity. The Journal of Pathology.

Dent, A. & Selvaratnam, R. (2022) Measuring magnesium – Physiological, clinical, and analytical perspectives. Clinical Biochemistry. 105-106. 1-15.

Faust, K., Lee, M. K., Dent, A., Fiala, C., Portante, A., Rabindranath, M., Alsafwani, N., Gao, A., & Diamandis, P. (2022) Integrating morphologic and molecular histopathological features through whole slide image registration and deep learning. Neuro-Oncology Advances. 4 (1).

Faust, K., Roohi, A., Leon, A. J., Leroux, E., Dent, A., Evans, A. J., Pugh, T. J., Kalimuthu, S. N., Djuric, U., & Diamandis, P. (2020). Unsupervised Resolution of Histomorphologic Heterogeneity in Renal Cell Carcinoma Using a Brain Tumor-Educated Neural Network. JCO Clinical Cancer Informatics. 4. 811-821.

Dent, A., Sarwar, S., Faust, K., Richer, M., Djuric, U., Van Ommeren, R., & Diamandis, P. (2019). Physicians perspectives on integration of artificial intelligence into diagnostic pathology. npj Digital Medicine. 2 (28).

de Snoo ML, Frankland PW: Neurobiological mechanisms of forgetting across timescales. Current Opinion in Neurobiology. 2025, 90:102972.

De Snoo ML, Miller AMP, Ramsaran AI, Josselyn SA, Frankland PW. (2023) Exercise accelerates place cell representational drift. Current Biology. 33(3):R96-R97. doi:10.1016/j.cub.2022.12.033.

Miller AMP, Jacob AD, Ramsaran, AI, De Snoo ML, Josselyn SA, & Frankland PW. (2023). Emergence of a predictive model in the hippocampus. Neuron, 111(12), 1952-1965.e1955. doi:10.1016/j.neuron.2023.03.011

Ramsaran AI, Wang Y, Golbabaei A, Aleshin S, De Snoo, ML, Yeung BA, Rashid AJ, Awasthi A, Lau J, Tran LM, Ko SY, Abegg A, Duan LC, McKenzie C, Gallucci J, Ahmed M, Kaushik R, Dityatev A, Josselyn SA, Frankland PW (2023). A shift in the mechanisms controlling hippocampal engram formation during brain maturation. Science, 380(6644), 543-551. doi:10.1126/science.ade6530

Guskjolen A, Dhaliwal J, Parra JDL., Epp JR, Ko S, Chahley E, De Snoo M, Solari M, Panesar P, Snyder J, Duan X, Sanes JR, Josselyn SA, Frankland PW (2023) Neurogenesis-mediated circuit remodeling reduces engram reinstatement and promotes forgetting. bioRxiv, doi:2023.2010.2010.561722.

Nim S, O’Hara, DM, Corbi-Verge C, Perez-Riba A, Fujisawa K, Kapadia M, Chau H, Albanese F, Pawar G, De Snoo ML, Ngana SG, Kim J, El-Agnaf OMA, Rennella E, Kay LE, Kalia SK, Kalia LV, Kim PM (2023). Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease. Nature Communications, 14(1), 2150. doi:10.1038/s41467-023-37464-2

Friesen EF, Bailey J, Hyett S, Sedighi S, De Snoo ML, Williams K, Barry R, Erickson A, Forountan F, Selby P, Rosella L, Kurdyak P. Hazardous alcohol use and alcohol-related harm in rural and remote communities: a scoping review. The Lancet Public Health (2021) doi:10.1016/S2468-2667(21)00159-6

Kapadia M, De Snoo ML, Kalia LV, Kalia SK. Regulation of Parkin-Dependent Mitophagy by Bcl-2-Associated Athanogene (BAG) Family Members. Neural Regeneration Research (2021) doi:10.4103/1673-5374.295330

Friesen EL, Zhang YT, Earnshaw R, De Snoo ML, O’Hara DM, Agapova V, Chau H, Ngana S, Chen KS, Kalia LV, Kalia SK. BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts with the Autophagy Adaptor Protein p62. Frontiers in Cell and Developmental Biology. (2020) 8:716. doi:10.3389/fcell.2020.00716

Fomenko A, Lee D, McKinnon C, Lee EJ, De Snoo ML, Gondard E, Neudorfer C, Hamani C, Lozano AM, Kalia LV, Kalia SK. Deep brain stimulation of the medial septal nucleus induces expression of a virally delivered reporter gene in dentate gyrus. Frontiers in Neuroscience, section Neural Technology (2020). doi: 10.3389/fnins.2020.00463

Mckinnon C, De Snoo ML, Gondard E, Neudorfer C, Ngana GS, Brotchie JM, Koprich JB, Lozano AM, Kalia LV, Kalia SK. Early Impairment of the Ubiquitin Proteasome System in Dopaminergic Neurons Caused by α-Synuclein. Acta Neuropathologica Communications (2020). doi:10.1186/s40478-020-0894-0

De Snoo ML*, Friesen EL*, Zhang YT, Agapova V, Chau H, Pellerito O, Tang MY, Durcan TM, Fon EA, Kalia LV, Kalia SK. Bcl-2 associated athanogene 5 (BAG5) Regulates Parkin-Dependent Mitophagy and Cell Death Cell Death and Disease (2019). doi:10.1038/s41419-019-2132-x

Foroutan F, Friesen EL, Clark KE, Motaghi S, Zyla R, Lee Y, Kamran R, Ali E, De Snoo M, Orchanian-Cheff A, Ribic C, Treleaven DJ, Guyatt G, Meade MO. Risk Factors for 1-Year Graft Loss After Kidney Transplantation: Systematic Review and Meta-Analysis. Clinical Journal of the American Society of Nephrology. (2019) doi:10.2215/CJN.05560519

Friesen EL*, De Snoo ML*, Rajendran L, Kalia LV, Kalia SK, Chaperone-Based Therapies for Disease Modification in Parkinson’s Disease. Parkinson’s Disease (2017). doi:10.1155/2017/5015307

Dhaliwal, A., Ma, J., Zheng, M., Lyu, Q., Rajora, M.A., Ma, S., Oliva, L., Ku, A., Valic, M., Wang, B. and Zheng, G., 2024. Deep learning for automatic organ and tumor segmentation in nanomedicine pharmacokinetics. Theranostics, 14(3), p.973.

Rajora, M.A.*, Dhaliwal, A.*, Zheng, M., Choi, V., Overchuk, M., Lou, J.W., Pellow, C., Goertz, D., Chen, J. and Zheng, G., 2024. Quantitative Pharmacokinetics Reveal Impact of Lipid Composition on Microbubble and Nanoprogeny Shell Fate. Advanced Science, 11(4), p.2304453.

Kwon, N., Jasinevicius, G.O., Kassab, G., Ding, L., Bu, J., Martinelli, L.P., Ferreira, V.G., Dhaliwal, A., Chan, H.H., Mo, Y. and Bagnato, V.S., 2023. Nanostructure‐Driven Indocyanine Green Dimerization Generates Ultra‐Stable Phototheranostics Nanoparticles. Angewandte Chemie International Edition, 62(28), p.e202305564.

Margalik, DA, Chen, J, Ho, T, Ding, L, Dhaliwal, A, Doria, AS and Zheng, G. (2022). Prolonged Circulating Lipid Nanoparticles Enabled by High-Density Gd-DTPA-Bis (stearylamide) for Long-Lasting Enhanced Tumor Magnetic Resonance Imaging. Bioconjugate Chemistry. 33(11): 2213-2222.

Yoo, K, Dhaliwal, A, Chen, J, Sheeran, PS and Zheng, G. (2021) Synthesis and Characterization of Multi-Modal Phase-Change Porphyrin Droplets. Journal of Visualized Experiments: Jove. (176).

Dhaliwal A and Zheng G. (2019). Improving accessibility of EPR-insensitive tumor phenotypes using EPR-adaptive strategies: Designing a new perspective in nanomedicine delivery. Theranostics. 9.26: 8091.

Elias GJB*, Germann J*, Boutet A, Beyn ME, Giacobbe P, Song HN, Choi KS, Mayberg HS,

Kennedy SK, Lozano AM. Local Neuroanatomical and Tract-Based Proxies of Optimal

Subcallosal Cingulate Deep Brain Stimulation. Brain Stimulation. 2023 Sep;16(5) 5:1259–72.

https://doi.org/10.1016/j.brs.2023.08.014.

Elias GJB*, Loh A*, Germann J, Boutet A, Gwun D, Yamamoto K, Sarica C, Azevedo P, Zemmar A,

Pinto J, et al. Neural Correlates of Optimal Deep Brain Stimulation for Cervical Dystonia. Annals of

Neurology. 2022 Sep;92(3):418–424. https://doi.org/10.1002/ana.26450.

Elias GJB*, Germann J*, Boutet A, Loh A, Li B, Pancholi A, Beyn ME, Naheed A, Bennett N, Pinto

J, et al. 3T MRI of rapid brain activity changes driven by subcallosal cingulate deep brain stimulation.

Brain. 2022 Jun;145(6):2214–2226. https://doi.org/10.1093/brain/awab447.

Elias GJB*, Germann J*, Loh A, Boutet A, Pancholi A, Beyn ME, Bhat V, Woodside DB, Giacobbe P,

Kennedy SH, et al. (2022). Habenular Involvement in Response to Subcallosal Cingulate Deep Brain

Stimulation for Depression. Frontiers in Psychiatry. 2022 Feb;13:810777.

https://doi.org/10.3389/fpsyt.2022.810777.

Elias GJB*, Germann J*, Boutet A, Pancholi A, Beyn ME, Bhatia K, Neudorfer C, Loh A, Rizvi SJ,

Bhat V, et al. Structuro-functional surrogates of response to subcallosal cingulate deep brain

stimulation for depression. Brain. 2022 Jan;145(1):362–377. https://doi.org/10.1093/brain/awab284.

Elias GJB*, Yamamoto K*, Beyn ME, Zemmar A, Loh A, Sarica C, Germann J, Parmar R, Wong EHY, Boutet A, et al. Neuromodulation for Pain: A Comprehensive Survey and Systematic Review of Clinical Trials and Connectomic Analysis of Brain Targets. Stereotactic and Functional Neurosurgery. 2022 Jan;100(1):14–25. https://doi.org/10.1159/000517873.

Elias GJB*, Boutet A*, Parmar R, Wong EHY, Germann J, Loh A, Paff M, Pancholi A, Gwun D, Chow CT, et al.. Neuromodulatory treatments for psychiatric disease: A comprehensive survey of the clinical trial landscape. Brain Stimulation. 2021 Sep;14(5):1393–1403. https://doi.org/10.1016/j.brs.2021.08.021.

Elias GJB*, Loh A*, Gwun D, Pancholi A, Boutet A, Neudorfer C, Germann J, Namasivayam A, Gramer R, Paff M, et al. Deep brain stimulation of the brainstem. Brain. 2021 Mar;144(3):712–723. https://doi.org/10.1093/brain/awaa374.

Elias GJB*, Boutet A*, Joel SE, Germann J, Gwun D, Neudorfer C, Gramer RM, Algarni M, Paramanandam V, Prasad S, et al. Probabilistic Mapping of Deep Brain Stimulation: Insights from 15 Years of Therapy. Annals of Neurology. 2021 Mar;89(3):426–443. https://doi.org/10.1002/ana.25975.

Elias GJB, Germann J, Neudorfer C, Namasivayam AA, Loh A, Gramer RM, Ibrahim GM, Valiante T, Tomaszczyk JC, McAndrews MP, et al. Impact of Mesial Temporal Lobe Resection on Brain Structure in Medically Refractory Epilepsy. World Neurosurgery. 2021 Aug;152:e652–e665. https://doi.org/10.1016/j.wneu.2021.06.039.

Elias GJB*, Germann J*, Boutet A, Narang K, Neudorfer C, Horn A, Loh A, Deeb W, Salvato B, Almeida L, et al. Brain structures and networks responsible for stimulation-induced memory flashbacks during forniceal deep brain stimulation for Alzheimer’s disease. Alzheimer’s & Dementia. 2021 May;17(5):777–787. https://doi.org/10.1002/alz.12238.

Elias GJB, De Vloo P, Germann J, Boutet A, Gramer RM, Joel SE, Morlion B, Nuttin B, Lozano AM. Mapping the network underpinnings of central poststroke pain and analgesic neuromodulation. Pain. 2020 Dec;161(12):2805–2819. https://doi.org/10.1097/j.pain.0000000000001998.

Elias GJB*, Harmsen IE*, Beyn ME, Boutet A, Pancholi A, Germann J, Mansouri A, Lozano CS, Lozano AM. Clinical trials for deep brain stimulation: Current state of affairs. Brain Stimulation. 2020 Mar-Apr;13(2):378–385. https://doi.org/10.1016/j.brs.2019.11.008.

Elias GJB, Giacobbe P, Boutet A, Germann J, Beyn ME, Gramer RM, Pancholi A, Joel SE, Lozano AM. Probing the Circuitry of Panic with Deep Brain Stimulation: Connectomic Analysis and Review of the Literature. Brain Stimul. 2020 Jan-Feb;13(1);10-14. https://doi.org/10.1016/j.brs.2019.09.010.

Elias GJB*, Ranjan M*, Boutet A, Zhong J, Chu P, Germann J, Devenyi GA, Chakravarty MM, Fasano A, Hynynen K, et al. Tractography-based targeting of the ventral intermediate nucleus: accuracy and clinical utility in MRgFUS thalamotomy. J. Neurosurg. 2020 Oct;133(4):1002–1009. https://doi.org/10.3171/2019.6.JNS19612.

Elias GJB, Lozano AM. Response to ‘Cerebellum as a possible target for neuromodulation after stroke’. Brain Stimulation. 2018 Nov-Dec;11(6):1395–1396. https://doi.org/10.1016/j.brs.2018.08.007.

Elias GJB, Namasivayam AA, Lozano AM. Deep brain stimulation for stroke: Current uses and future directions. Brain Stimulation. 2018 Jan-Feb;11(1):3–28. https://doi.org/10.1016/j.brs.2017.10.005.

Elias GJB, Abbas A, Loh A, Germann J, Schwartz ML. A Historical Perspective on the Role of Imaging in Deep Brain Stimulation. In: Boutet A, Lozano AM, editors. Magnetic Resonance Imaging in Deep Brain Stimulation. Springer International Publishing: 2022, pp. 5–16. https://doi.org/10.1007/978-3-031-16348-7_2.

Elias GJB, Germann J, Loh A, Boutet A, Taha A, Wong EHY, Parmar R, Lozano AM. Normative connectomes and their use in DBS. In: Horn A, editor. Connectomic Deep Brain Stimulation. Elsevier: 2022, pp. 245–274. https://doi.org/10.1016/B978-0-12-821861-7.00014-2.

Lee, D.J., Elias, G.J.B., Lozano, A.M. Neuromodulation for the treatment of eating disorders and obesity: Review. Therapeutic Advances in Psychopharmacology 2017. In Press.

King, N.K.K., Krishna, V., Basha, D., Elias, G., Sammartino, F., Hodaie, M., Lozano, A.M., and Hutchison, W.D. (2016). Microelectrode recording findings within the tractography-defined ventral intermediate nucleus. J. Neurosurg. 1–7.

Murphy, K., Elias, G., Steppan, J., Boxley, C., Balagurunathan, K., Victor, X., Meaders, T., and Muto, M. (2016a). Percutaneous Treatment of Herniated Lumbar Discs with Ozone: Investigation of the Mechanisms of Action. J Vasc Interv Radiol 27, 1242–1250.e3.

Krishna, V., Sammartino, F., Yee, P., Mikulis, D., Walker, M., Elias, G., and Hodaie, M. (2016). Diffusion tensor imaging assessment of microstructural brainstem integrity in Chiari malformation Type I. J. Neurosurg. 1–8.

Murphy, K., Oaklander, A.L., Elias, G., Kathuria, S., and Long, D.M. (2016b). Treatment of 213 Patients with Symptomatic Tarlov Cysts by CT-Guided Percutaneous Injection of Fibrin Sealant. AJNR Am J Neuroradiol 37, 373–379.

Krishna, V., Elias, G., Sammartino, F., Basha, D., King, N.K.K., Fasano, A., Munhoz, R., Kalia, S.K., Hodaie, M., Venkatraghavan, L., et al. (2015). The effect of dexmedetomidine on the firing properties of STN neurons in Parkinson’s disease. Eur. J. Neurosci. 42, 2070–2077.

Chen, L., Elias, G., Yostos, M.P., Stimec, B., Fasel, J., and Murphy, K. (2015). Pathways of cerebrospinal fluid outflow: a deeper understanding of resorption. Neuroradiology 57, 139–147.

Murphy, K.J., Elias, G., Jaffer, H., and Mandani, R. (2013). A study of inventiveness among Society of Interventional Radiology members and the impact of their social networks. J Vasc Interv Radiol 24, 931–937.

Lipsman, N., Woodside, D.B., Giacobbe, P., Hamani, C., Carter, J.C., Norwood, S.J., Sutandar, K., Staab, R., Elias, G., Lyman, C.H., et al. (2013). Subcallosal cingulate deep brain stimulation for treatment-refractory anorexia nervosa: a phase 1 pilot trial. Lancet 381, 1361–1370.

Murphy, K.J., Elias, G., Jaffer, H., and Mandani, R. (2012). Where good ideas come from: where the wild things are! J Vasc Interv Radiol 23, 494–496.

Li, AY, Gaebe K, Zulfiqar A, Lee G, Jerzak KJ, Sahgal A, Habbous S, Erickson AW, Das S. (2023) Association of brain metastases with survival in patients with limited or stable extracranial disease: a systematic review and meta-analysis. JAMA Network Open 6(2):e230475. PMID: 36821113.

Hendrikse L, Haldipur P, Saulnier O, Millman J, Sjoboen A, Erickson AW, Ong W, Gordon V, Coudière-Morrison L, Mercier A, et al. (2022) Failure of Differentiation of the Human Split Rhombic Lip Subventricular Zone Constitutes Group 4 Medulloblastoma. Nature 612, E12. PMID: 36131014.

Sherman M, Gaebe K, Li AY, Habbous S, Sahgal A, Raphael MJ, Erickson AW, Das S. (2022) Erythroblastic oncogene B-2 status and intracranial metastatic disease in patients with gastrointestinal cancer: a systematic review. Journal of Neuro-Oncology. PMID: 36372832.

Gaebe K, Li AY, Park A, Parmar A, Lok BH, Sahgal A, Chan KKW, Erickson AW, Das S (2022) Stereotactic radiosurgery versus whole brain radiation therapy in patients with intracranial metastatic disease and small cell lung cancer: a systematic review and meta-analysis. Lancet Oncology. S1470-2045(22)00271-6. PMID: 35644163.

Erickson AW, Habbous S, Wright F, Lofters AK, Jerzak KJ, Das S. (2021) Targeted therapy and intracranial metastatic disease: a population-based retrospective cohort study. JAMA Oncology. 7(8):1220-1224. PMID: 34081080.

Erickson AW, Habbous S, Hoey C, Jerzak KJ, Das S. (2021) Dual- versus single-agent HER2 inhibition and incidence of intracranial metastatic disease in HER2-positive breast cancer: a systematic review and meta-analysis. npj Breast Cancer. 7:17. PMID: 33602948.

Erickson AW, Ghodrati F, Habbous S, Jerzak KJ, Sahgal A, Ahluwahlia M, Das S. (2020) HER2-targeted therapy prolongs survival in patients with HER2-positive breast cancer and intracranial metastatic disease: a systematic review and meta-analysis. Neuro-Oncology Advances. 2(1):vdaa136. PMID: 33305268.

Garcia-Segura ME, Erickson AW, Jairath R, Munoz DG, Das S. (2020). Necrosis and Brain Invasion Predict Radio-Resistance and Tumor Recurrence in Atypical Meningioma: A Retrospective Cohort Study. Neurosurgery. 88(1): E42-48. PMID: 32818240.

Erickson AW, Brastianos PK, & Das S. (2020). Assessment of Effectiveness and Safety of Osimertinib for Patients With Intracranial Metastatic Disease: A Systematic Review and Meta-analysis. JAMA Network Open. 3(3):e201617. PMID: 32211870.

Eldeeb MA*, Fallahi A*, Soumbasis A*, Bayne AN, Trempe JF, Fon EA. Mitochondrial Import Stress and PINK1-Mediated Mitophagy: the Role of The PINK1-TOM-TIM23 Supercomplex. Autophagy. 2024. *Equal contribution.

Eldeeb MA*, Bayne AN*, Fallahi A, Goiran T, MacDougall EJ, Soumbasis A, Zorca CE, Tabah JJ, Thomas RA, Karpilovsky N, Mathur M, Durcan TM, Trempe JF, Fon EA. TOM20 Gates PINK1 Activity And Mediates Its Tethering Of The TOM And TIM23 Translocases Upon Mitochondrial Stress. Proceedings of the National Academy of Science (PNAS). 2024; 121(10). *Equal contribution.

Fallahi A, Pickel L. Celebrating the Centennial of the UTMJ: From the Archives-The Last Quarter Century. University of Toronto Medical Journal. 2023; 100(2):7-15.

Eldeeb MA, Thomas R, Ragheb M, Fallahi A, Fon EA. Mitochondrial Quality Control in Health and in Parkinson’s Disease. Physiological Reviews. 2022. DOI: https://doi.org/10.1152/physrev.00041.2021 

Zorca CE, Fallahi A, Luo S, Eldeeb MA. Multifaceted Targeted Protein Degradation systems for different cellular compartments. BioEssays. 2022; 44:6. DOI: https://doi.org/10.1002/bies.202200008

Fallahi A, Hernandez G, Restrepo-Lozano JM, Flores C. Effects of adolescent cannabinoid administration in mice on behavioural inhibition and susceptibility to stress during adulthood. McGill Science Undergraduate Research Journal (MSURJ). 2021; 16:31-37. DOI: https://doi.org/10.26443/msurj.v16i1.57

McInerney SJ, Fallahi A, Edgar NE, Ceniti AK, Rizvi SJ, Beder M, Bergmans Y, Kennedy SH. Suicide-related presentations of homeless individuals to an inner-city emergency department. General Hospital Psychiatry. 2020; 63:5. DOI: 10.1016/j.genhosppsych.2019.05.001

Wang AA, Luessi F, Neziraj T, Pössnecker E, Zuo M, Engel S, Hanuscheck N, Florescu A, Bugbee E, Ma XI, Rana F, Lee D, Ward LA, Kuhle J, Himbert J, Schraad M, van Puijenbroek E, Klein C, Urich E, Ramaglia V, Pröbstel AK, Zipp F, Gommerman JL. B cell depletion with anti-CD20 promotes neuroprotection in a BAFF-dependent manner in mice and humans. Sci Transl Med. 2024 Mar 6;16(737):eadi0295. doi: 10.1126/scitranslmed.adi0295. Epub 2024 Mar 6. PMID: 38446903.

Isho, B., Florescu A., Wang, A.A., Gommerman, J.L. Fantastic IgA plasma cells and where to find them. Immunological Reviews. 2021, DOI: https://doi.org/10.1111/imr.12980 

Ramaglia, V., Florescu, A., Zuo, M., Sheikh-Mohamed, S., and Gommerman, J.L. Stromal Cell–Mediated Coordination of Immune Cell Recruitment, Retention, and Function in Brain-Adjacent Regions. J Immunol. 2021; 206 (2) 282-291; DOI: https://doi.org/10.4049/jimmunol.2000833

Bruton, K., Spill, P., Vohra, S., Baribeau, O., Manzoor, S., Gadkar, S., Davidson, M., Walker, T., Koenig, J.F.E., Ellenbogen, Y., Florescu, A., Wen, J., Chu, D., Waserman, S., Jimenez-Saiz, R., Epelman, S., Robbins, C., and Jordana, M. Interrupting reactivation of immunological memory diverts the allergic response and prevents anaphylaxis. Journal of Allergy and Clinical Immunology. 2020; DOI: https://doi.org/10.1016/j.jaci.2020.11.042.

Alcock BP, Raphenya AR, Lau TT, Tsang KK, Bouchard M, Edalatmand A, Huynh W, Nguyen AL, Cheng AA, Liu S, Min SY, Miroshnichenko A, Tran HK, Werfalli RE, Nasir JA, Olonin M, Speicher DJ, Florescu A, Singh B, Faltyn M, Hernandez-Koutoucheva A, Sharma AN, Bordeleau E, Pawlowski AC, Zubyk HL, Dooley D, Griffiths E, Maguire F, Winsor GL, Beiko RG, Brinkman FSL, Hsiao WWL, Domselaar GV and McArthur AG. CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database. Nucleic Acids Research. 2019;48(D1):D517-521.

Myran DT, Friesen EL, Talarico R, Gaudreault A, Taljaard M, Hobin E, Smith BT, Schwartz N, Giesbrecht N, Crépault JF, Tanuseputro P. The association between alcohol retail access and health care visits attributable to alcohol for individuals with and without a history of alcohol‐related health‐care use. Addiction. 2024 May 28. https://doi.org/10.1111/add.16566 

Friesen EL, Konikoff L, Dickson S, Myran DT. Geographic clustering of cannabis stores in Canadian cities: A spatial analysis of the legal cannabis market 4 years post‐legalisation. Drug and alcohol review. 2024 May 27. https://doi.org/10.1111/dar.13869 

Friesen EL, Mataruga A, Bolton J, Kurdyak P. Characterizing the clinical subgroups of individuals who present to the emergency department for alcohol-related harms in Ontario, Canada: A latent class analysis. Psychiatry Research. 2024 Mar 1;333:115726. https://doi.org/10.1016/j.psychres.2024.115726 

Friesen EL, Mataruga A, Nickel N, Kurdyak P, Bolton JM. Outcomes in Clinical Subgroups of Patients With Alcohol-Related Hospitalizations. JAMA Network Open. 2024 Jan 2;7(1):e2353971-. https://doi.org/10.1001/jamanetworkopen.2023.53971 

Schwartz N, Smith BT, Fu SH, Myran D, Friesen EL, Hobin E. The impacts of selling alcohol in grocery stores in Ontario, Canada: a before after study. Journal of Studies on Alcohol and Drugs. 2023 Aug 30:jsad-23. https://doi.org/10.15288/jsad.23-00113 

Friesen EL, Yu W, Kurdyak P. Outpatient psychiatric service use is associated with a reduced risk of 1‐year readmission and mortality following alcohol‐related hospitalizations: A historical cohort study. Acta Psychiatrica Scandinavica. 2023 May 24. https://doi.org/10.1111/acps.13560

Myran D, Friesen EL, Pugliese M, Milani C, Kurdyak P, Saraswat M, Tanuseputro P. Changes in health service use due to alcohol during the COVID-19 pandemic among individuals with and individuals without pre-existing alcohol-related medical diagnoses. Canadian Journal of Public Health. 2023 Apr;114(2):185-94. https://doi.org/10.17269/s41997-023-00739-8 

Friesen EL, Staykov E, Myran DT. Understanding the association between neighbourhood socioeconomic status and grocery store alcohol sales following market liberalization in Ontario, Canada. Canadian Journal of Public Health. 2023 Apr;114(2):254-63. https://doi.org/10.17269/s41997-022-00694-w 

Myran DT, Friesen EL, Dickson S, Konikoff L, Arora G, Tanuseputro P. Access to legal cannabis market in Canada over the four years following non‐medical cannabis legalisation. Drug and Alcohol Review. 2023 Mar 18. https://doi.org/10.1111/dar.13650 

Myran DT, Friesen EL, Pugliese M, Milani C, Tanuseputro P. Changes in mortality for the general population and individuals with pre-pandemic acute care for alcohol or opioids during the COVID-19 pandemic in Ontario, Canada. The Canadian Journal of Psychiatry. 2023 Feb 14. https://doi.org/10.1177/07067437231156000 

Friesen EL, Yu W, Buajitti E, Selby P, Rosella L, Kurdyak P. Clarifying rural‐urban disparities in alcohol‐related emergency department visits and hospitalizations in Ontario, Canada: A spatial analysis. The Journal of Rural Health. 2023 Jan;39(1):223-32. https://doi.org/10.1111/jrh.12702 

Friesen EL, Kurdyak P, Jewett R, Smith BT, Hobin E, Tanuseputro P, Myran DT. Associations between the physical availability of alcohol and alcohol use: regional variation across 15 major cities in Ontario, Canada. Journal of studies on alcohol and drugs. 2022 Nov;83(6):839-48. https://doi.org/10.15288/jsad.21-00402 

Friesen EL, Myran D, Yu W, Rosella L, Selby P, Kurdyak P. Rural-urban disparities in post-discharge outcomes following alcohol-related hospitalizations in Ontario, Canada: A retrospective cohort study. Drug and Alcohol Dependence. 2022 Sep 1;238:109568. https://doi.org/10.1016/j.drugalcdep.2022.109568 

Foroutan F, Malik A, Clark KE, Buchan TA, Yang H, Cheong G, Pezzutti O, Kim I, Gupta R, Tan C, Samman A, Friesen EL, Akhtar A, Rigobon A, Stein M, Nunez J, Sidhu A, Heels-Ansdell D, Guyatt G, Meade MO. Predictors of 1-year Mortality after Adult Lung Transplantation: Systematic Review and Meta-analyses. The Journal of Heart and Lung Transplantation. 2022. https://doi.org/10.1016/j.healun.2022.03.017 

Friesen EL, Bailey J, Hyett S, Sedighi S, de Snoo ML, Williams K, Barry R, Erickson A, Foroutan F, Selby P, Rosella L. Hazardous alcohol use and alcohol-related harm in rural and remote communities: a scoping review. The Lancet Public Health. 2021 Nov 10. https://doi.org/10.1016/S2468-2667(21)00159-6 

Kurdyak P, Friesen EL, Young JT, Borschmann R, Iqbal J, Huang A, et al. Prevalence of Mental Health and Addiction Service use Prior to and During Incarceration in Provincial Jails in Ontario, Canada: A Retrospective Cohort Study: Prévalence de l’utilisation des services de santé mentale et de dépendance avant et durant l’incarcération dans les prisons provinciales de l’Ontario, Canada: une étude de cohorte rétrospective. The Canadian Journal of Psychiatry. 2021. https://doi.org/10.1177/07067437211055414 

Friesen E, Kurdyak P, Gomes T, Kolla G, Leece P, Zhu L, et al. The impact of the COVID-19 pandemic on opioid-related harm in Ontario. Science Briefs of the Ontario COVID-19 Science Advisory Table. 2021;2:42. https://doi.org/10.47326/ocsat.2021.02.42.1.0 

Friesen EL, Young S. Experiencing homelessness as a risk factor for negative treatment outcomes among individuals receiving outpatient treatment for opioid use disorder in the United States. University of Toronto Medical Journal. 2021;98(2):56-62.

Friesen EL, Zhang YT, Earnshaw R, De Snoo ML, O'Hara DM, Agapova V, Chau H, Ngana S, Chen KS, Kalia LV, Kalia SK. BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62. Front Cell Dev Biol. 2020 Aug 4;8:716. https://doi.org/10.3389/fcell.2020.00716 

Friesen EL, Kurdyak P. Alcohol use and alcohol-related harm in rural and remote communities: protocol for a scoping review. BMJ Open. 2020;10(8):e036753. http://dx.doi.org/10.1136/bmjopen-2019-036753 

Friesen EL, Kurdyak P. The impact of psychiatric comorbidity on treatment discontinuation among individuals receiving medications for opioid use disorder. Drug and alcohol dependence. 2020;216:108244. https://doi.org/10.1016/j.drugalcdep.2020.108244 

Friesen EL, Foroutan F, Krakovsky J, Chih S, Ross H, Billia F, et al. Utility of the INTERMACS profile at the time of assessment for heart transplant. Clinical Transplantation. 2020;34(3):e13796. https://doi.org/10.1111/ctr.13796 

Wang X, Friesen E, Müller I, Lemieux M, Dukart R, Maia IB, et al. Rapid Generation of Human Neuronal Cell Models Enabling Inducible Expression of Proteins-of-interest for Functional Studies. Bio-protocol. 2020;10(9). https://doi.org/10.21769/bioprotoc.3615 

De Snoo ML, Friesen EL, Zhang YT, Earnshaw R, Dorval G, Kapadia M, et al. Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death. Cell Death Dis. 2019;10(12):907. https://doi.org/10.1038/s41419-019-2132-x 

Foroutan F, Guyatt G, Friesen E, Lozano LEC, Sidhu A, Meade M. Predictors of 1-year mortality in adult lung transplant recipients: a systematic review and meta-analysis. Systematic reviews. 2019;8(1):1-5. https://doi.org/10.1186/s13643-019-1049-x 

Foroutan F, Friesen EL, Clark KE, Motaghi S, Zyla R, Lee Y, et al. Risk factors for 1-year graft loss after kidney transplantation: systematic review and meta-analysis. Clinical Journal of the American Society of Nephrology. 2019;14(11):1642-50. https://doi.org/10.2215/cjn.05560519 

Friesen EL. The Landscape of Mental Health Services in Rural Canada. University of Toronto Medical Journal. 2019;96(2):47-52.

Picillo M, Lizarraga KJ, Friesen EL, Chau H, Zhang M, Sato C, et al. Parkinsonism due to A53E α‐synuclein gene mutation: Clinical, genetic, epigenetic, and biochemical features. Movement Disorders. 2018;33(12):1950-5. https://doi.org/10.1002/mds.27506 

Friesen EL, De Snoo ML, Rajendran L, Kalia LV, Kalia SK. Chaperone-based therapies for disease modification in Parkinson’s disease. Parkinson’s disease. 2017. https://doi.org/10.1155/2017/5015307 

Garrido AN, House R, Lipszyc JC, Liss GM, Holness DL, Tarlo SM. Cleaning agent usage in healthcare professionals and relationship to lung and skin symptoms. Journal of Asthma. 2021. DOI: https://doi.org/10.1080/02770903.2021.1871740

Garrido, A.N., Supijono, E., Boshara, P., Douglas, S.J., Stronghill, P.E., Li, B., Nambara, E., Kliebenstein, D.J. and Riggs, C.D. (2020), flasher, a novel mutation in a glucosinolate modifying enzyme, conditions changes in plant architecture and hormone homeostasis. Plant J, 103: 1989-2006. https://doi.org/10.1111/tpj.14878

Gascon, B., Panjwani, A. A., Mazzurco, O., & Li, M. (2022). Screening for Distress and Health Outcomes in Head and Neck Cancer. Current Oncology, 29(6), 3793-3806.

Gascon, B., Leung, Y., Espin-Garcia, O., Rodin, G., Chu, D. and Li, M., 2021. Suicide risk screening and suicide prevention in patients with cancer. JNCI cancer spectrum, 5(4), p.pkab057.

Gascon, B., Rodin, G., Zimmermann, C., & Li, M. (2022). Screening for Psychological Distress in the Palliative Care Setting. Handbook of Psychiatry in Palliative Medicine 3rd Edition: Psychosocial Care of the Terminally Ill, 181.

Al-Awadhi, M., Gascon, B., Albarak, N., Aldeweesh, G., Hamadah, A., Abdulkarim, H., ... & Li, M. (2022). Implementation of the Distress Assessment and Response Tool at the Kuwait Cancer Control Centre. Journal of Psychosocial Oncology Research and Practice, 4(3).

Panjwani, A. A., Aguiar, S., Gascon, B., Brooks, D. G., & Li, M. (2022). Biomarker opportunities in the treatment of cancer-related depression. Trends in Molecular Medicine.

Giovino, C., Subasri, V., Telfer, T., Malkin, D. (2024) New Paradigms in the Clinical Management of Li–Fraumeni Syndrome. Cold Spring Harb Perspect Med.

doi: 10.1101/cshperspect.a041584

Chan K, Farias AG, Lee H, Guvenc F, Mero P, Brown KR, Ward H, Billmann M, Aulakh K, Astori A, Haider S, et al. Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors. Heliyon. 2023 Jan; 9(1):e12744. doi: 10.1016/j.heliyon.2022.e12744.

Lacoste J, Haghighi M, Haider S, Lin ZY, Segal D, Reno C, Qian WW, Xiong X, Shafqat-Abbasi H, Ryder PV, Senft R, et al. Pervasive mislocalization of pathogenic coding variants underlying human disorders. bioRxiv [Preprint]. 2023 Sep 5:2023.09.05.556368. doi: 10.1101/2023.09.05.556368.

Poirson J, Cho H, Dhillon A, Haider S, Imrit AZ, Lam MHY, Alerasool N, Lacoste J, Mizan L, Wong C, Gingras AC, et al. Proteome-scale discovery of protein degradation and stabilization effectors. Nature. 2024 Mar 20. doi: 10.1038/s41586-024-07224-3.

Rosella LC, Harish V. Machine learning applied to routinely collected health data. Healthcare Quarterly. 2022. (In Press).

Yi SE, Harish V, Gutierrez J, Ravaut M, Kornas K, Watson T, Poutanen T, Ghassemi M, Volkovs M, Rosella LC. Predicting hospitalisations related to ambulatory care sensitive conditions with machine learning for population health planning: derivation and validation cohort study. BMJ Open. 2022 Apr; 12(4):e051403 doi: 10.1136/bmjopen-2021-051403

Harish V, Buajitti E, Burrows H, Posen J, Bogoch I, Gubbay J, Boggild A, Rosella LC, Morris S. 737. Geographic Clustering of Travel-acquired Infections in Ontario, Canada, 2008-2020. Open Forum Infectious Diseases. 2021 Nov; 8 (Supplement 1): S466-467. https://doi.org/10.1093/ofid/ofab466.934 

Berry I, O’Neill M, Sturrock SL, Wright JE, Acharya K, Brankston G, Harish V, Kornas K, Maani N, Naganathan T, Obress L, Rossi T, Simmons AE, Van Camp M, Xie X, Tuite AR, Greer AL, Fisman DN, Soucy JPR. A sub-national real-time epidemiological and vaccination database for the COVID-19 pandemic in Canada. Scientific Data. 2021 Jul; 8.  https://doi.org/10.1038/s41597-021-00955-2 

Ravaut M, Harish V, Sadeghi H, Leung KK, Volkovs M, Kornas K, Watson T, Poutanen T, Rosella LC. Development and validation of a machine learning model using administrative health data to predict onset of type 2 diabetes. JAMA Network Open. 2021 May; 4(5): e2111315-e2111315. doi:10.1001/jamanetworkopen.2021.11315

Harish V. The Syndemics of Emergency: How COVID-19 Demands a Holistic View of Public Health Promotion and Preparedness. American Journal of Public Health. 2021 Mar; 111(3): 353-354. doi:  10.2105/AJPH.2020.306116

Ravaut M, Sadeghi H, Leung KK, Volkovs M, Kornas K, Harish V, Watson T, Lewis GF, Weisman A, Poutanen T, Rosella LC. Predicting adverse outcomes due to diabetes complications with machine learning using administrative health data. NPJ Digital Medicine. 2021 Feb; 4(1):1-12. https://doi.org/10.1038/s41746-021-00394-8 

Mehta N, Harish V, Bilimoria K, Morgado F, Ginsburg S, Law M, Das S. Knowledge and Attitudes on Artificial Intelligence in Healthcare: A Provincial Survey Study of Medical Students. MedEd Publish. 2021 Mar. https://doi.org/10.15694/mep.2021.000075.1 

Harish V, Morgado F, Stern AD, Das S. Artificial Intelligence and Clinical Decision Making: The New Nature of Medical Uncertainty. Academic Medicine. 2020 Dec; 96(1): 31-36. doi: 10.1097/ACM.0000000000003707

McCoy L, Smith J, Anchuri K, Berry I, Pineda J, Harish V, Lam AT, Yi SE, Hu S, Rosella LC, Fine B. Characterizing early Canadian federal, provincial, territorial, and municipal nonpharmaceutical interventions in response to COVID-19: a descriptive analysis. CMAJ Open. 2020 Jul; 8(3):E545-E553. https://doi.org/10.9778/cmajo.20200100 

Berry I, Soucy JPR, Tuite A, Fisman D, COVID-19 Canada Open Data Working Group (incl Harish V). CMAJ. 2020 Apr; 192(15): E420. https://doi.org/10.1503/cmaj.75262 

Sasikumar S, Cohn M, Harmsen IE, Loh A, Cho SS, Sáenz-Farret M, Maciel R, Soh D, Boutet A, Germann J, Elias G, Youm A, Duncan K, Rowland NC, Strafella AP, Kalia SK, Lozano AM, Fasano A. Single-Trajectory Multiple-Target Deep Brain Stimulation for Parkinsonian Mobility and Cognition. Movement Disorders. 2022 Mar;37(3):635-640.

Harmsen IE, Wolff Fernandes F, Krauss JK, Lozano AM. Where are we with deep brain stimulation? A review of scientific publications and ongoing research. Stereotactic and Functional Neurosurgery. 2022 Feb 1:1-14.

Flouty O, Yamamoto K, Germann J, Harmsen IE, Jung HH, Cheyuo C, Zemmar A, Milano V, Sarica C, Lozano AM. Idiopathic Parkinson's disease and chronic pain in the era of DBS: A systematic review and meta-analysis. Journal of Neurosurgery. 2022 Feb. (Accepted).

Samuel N, Vetkas A, Pancholi A, Sarica C, Loh A, Germann J, Harmsen IE, Tasserie J, Milano V, Yamamoto K, Kalia SK, Kongkham PN, Lozano AM. A network-based approach to glioma surgery: insights from functional neurosurgery. Cancers. 2021 Dec 5;13(23):6127.

Marceglia S, Guidetti M, Harmsen IE, Loh A, Meoni S, Foffani G, Lozano AM, Moro E, Volkmann J, Priori A. Deep Brain Stimulation: Is It Time to Change Gears by Closing the Loop? Journal of Neural Engineering. 2021 Nov;18(6).

Elias GJB, Boutet A, Parmar R, Wong EHY, Germann J, Loh A, Paff M, Pancholi A, Gwun D, Chow CT, Gouveia FV, Harmsen IE, Beyn ME, Santarnecchi E, Fasano A, Blumberger DM, Kennedy SH, Lozano AM, Bhat V. Neuromodulatory treatments for psychiatric disease: A comprehensive survey of the clinical trial landscape. Brain Stimulation. 2021 Sep-Oct;14(5):1393-1403.

Guidetti M, Marceglia S, Loh A, Harmsen IE, Meoni S, Foffani G, Lozano AM, Moro E, Volkmann J, Priori A. Clinical perspectives of adaptive deep brain stimulation. Brain Stimulation. 2021 Aug;14(5):1238-1247.

Harmsen IE, Hasanova D, Elias GJB, Boutet A, Neudorfer C, Loh A, Germann J, Lozano AM. Trends in Clinical Trials for Spinal Cord Stimulation. Stereotact Funct Neurosurg. 2021;99(2):123-134. doi: 10.1159/000510775. Epub 2020 Nov 27. PMID: 33249416.

Khadka N, Harmsen IE, Lozano AM, Bikson M. Bio-heat model of kilohertz-frequency deep brain stimulation increases brain tissue temperature. Neuromodulation. 2020 Jun; 23(4):489-495.

Harmsen IE, Elias GJB, Beyn ME, Boutet A, Pancholi A, Germann J, Mansouri A, Lozano CS, Lozano AM. Clinical trials for deep brain stimulation: Current state of affairs. Brain Stimul. 2020 Mar-Apr;13(2):378-385. doi: 10.1016/j.brs.2019.11.008. Epub 2019 Nov 23. PMID: 31786180.

Harmsen IE. Empathy in autism spectrum disorder. Journal of Autism and Developmental Disorders. 2019 Oct; 49(10):3939-3955.

Harmsen IE, Lee DJ, Dallapiazza RF, De Vloo P, Chen R, Fasano A, Kalia SK, Hodaie M, Lozano AM. Ultra-high frequency deep brain stimulation at 10,000 Hz improves motor function. Movement Disorders. 2019 Jan; 34(1):146-148.

Harmsen IE, Rowland NC, Wennberg RA, Lozano AM. Characterizing the effects of deep brain stimulation with magnetoencephalography: A review. Brain Stimulation. 2018 May; 11(3):481-491.

Hétu MF, Brooks SC, Chan W, Herr J, Sivilotti MLA, O'Callaghan N, Latiu V, Newbigging J, Day AG, Norman PA, Hill B, Johri AM. HEART + score: integrating carotid ultrasound to chest pain assessment in the emergency department. CJEM. Published online May 24, 2024. doi:10.1007/s43678-024-00711-6

Grubic N, Hill B, Allan KS, et al. Mediators of the Association Between Socioeconomic Status and Survival After Out-of-Hospital Cardiac Arrest: A Systematic Review. Can J Cardiol. Published online January 10, 2024. doi:10.1016/j.cjca.2024.01.002

Mulvagh SL, Colella TJF, Gulati M, Crosier R, Allana S, Randhawa VK, Bruneau J, Pacheco C, Jaffer S, Cotie L, Mensour E, Clavel MA, Hill B, et al. The Canadian Women's Heart Health Alliance ATLAS on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women - Chapter 9: Summary of Current Status, Challenges, Opportunities, and Recommendations. CJC Open. 2023;6(2Part B):258-278. Published 2023 Dec 7. doi:10.1016/j.cjco.2023.12.001

Hill B, Grubic N, Liblik K, Johri AM. Patient Involvement in Care, Psychosocial Outcomes, and Quality of Life in Hypertrophic Cardiomyopathy: A Pilot Study. CJC Open. 2023;6(3):539-543. Published 2023 Nov 4. doi:10.1016/j.cjco.2023.11.002

Grubic N, Hill B, Allan KS, Dainty KN, Johri AM, Brooks SC. Community Interventions for Out-of-Hospital Cardiac Arrest in Resource-Limited Settings: A Scoping Review Across Low, Middle, and High-Income Countries. Prehosp Emerg Care. 2023;27(8):1088-1100. doi:10.1080/10903127.2023.2231559.

Johri AM, Glass C, Hill B, et al. The Evolution of Cardiovascular Ultrasound: A Review of Cardiac Point-of-Care Ultrasound (POCUS) Across Specialties. Am J Med. 2023;136(7):621-628. doi:10.1016/j.amjmed.2023.02.020

Grubic N, Allan KS, Drezner JA, Hill B, Johri AM. Public emotions and opinions following the sudden cardiac arrest of a young athlete: A sentiment analysis. Am J Emerg Med. 2023 May;67:179-181. doi: 10.1016/j.ajem.2023.03.015

Hill B, Grubic N, Williamson M, Phelan DM, Baggish AL, Dorian P, Drezner JA, Johri AM. Does cardiovascular preparticipation screening cause psychological distress in athletes? A systematic review. Br J Sports Med. 2023 Feb;57(3):172-178. doi: 10.1136/bjsports-2022-105918.

Brooks SC, Sivilotti MLA, Hétu MF, Norman PA, Day AG, O'Callaghan N, Latiu V, Newbigging J, Hill B, Johri AM. Focused carotid ultrasound to predict major adverse cardiac events among emergency department patients with chest pain. Can J Emerg Med. 2023 Jan;25(1):81-89. doi: 10.1007/s43678-022-00395-w.

 Bazoukis G, Hill B, Tse G, Naka KK. Ivabradine: pre-clinical and clinical evidence in the setting of ventricular arrhythmias. Hippokratia. 2022 Apr-Jun;26(2):49-54. PMID: 37188047; PMCID: PMC10177854.

 Grubic N, Hill B, Phelan D, Baggish A, Dorian P, Johri AM. Bystander interventions and survival after exercise-related sudden cardiac arrest: a systematic review. Br J Sports Med. 2022 Apr;56(7):410-416. doi: 10.1136/bjsports-2021-104623.

Nyayachavadi, A.; Sur, A. K.; Kulatunga, P.; Wang, Y.; Gomes, T. C.; Mooney, M.; Mason, G. T.; Hu, A.; Gu, X.; Rondeau-Gagné, S. Covalent Topochemical Photo-Cross-Linking of Diketopyrrolopyrrole-Based Polymers with Polydiacetylenes toward Tunable Mechanical and Electronic Properties. Chemistry of Materials. 2023, 35 (22), 9682-9691.

Hu, A.; Nyayachavadi, A.; Weires, M.; Garg, G.; Wang, S.; Rondeau-Gagné, S. Unravelling the Influence of Side-Chain Symmetry on Device Performance: Insights from Isoindigo-Based Polymers in Thin-Film Transistors. RSC Applied Polymers. 2023, 1, 292-303.

Yousefi, N.; Caba, C.; Hu, A.; Mooney, M.; Zhang, S.; Agostinis, A. D.; Mirhassani, M.; Ahamed, M. J.; Tong, Y.; Rondeau-Gagné, S. Building a Versatile Platform for the Detection of Protein–Protein Interactions Based on Organic Field-Effect Transistors. ACS Applied Electronic Materials. 2022, 4 (10), 4972-4981.

Huang, R., Kee, L., Gont, A., Meens, J., Ferens, F.G., Irwin, M.S., Ailles, L., Yuzwa, S.A., Robinson, C.M.φ, and Ohh, M.φ. Comparative single-cell transcriptomic profiling of patient-derived renal carcinoma cells in cellular and animal models of kidney cancer. FEBS Open Bio 15(4), 1-20 (2025).

Huang, R., Meens, J., Yuzwa, S., Ailles, L., Ohh, M.φ, and Robinson, C. M.φ Side population analysis in clear cell renal cell carcinoma. Biochem. Biophys. Res. Commun. 585, 196-202 (2021).

Gebregiworgis, T.*, Kano, Y.*, St-Germain, J., Radulovich, N., Udaskin, M., Mentes, A., Huang, R., Poon, B., He, W., Valencia-Sama, I., Robinson, C., Huestis, M., Miao, J., Yeh, J. J., Zhang, Z., Irwin, M., Lee, J., Tsao, M., Raught, B., Marshall, C.φ, Ohh, M.φ, and Ikura, Mφ. The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors. Nat. Commun. 12, 6274 (2021).

Huang, R.*, Huestis, M.*, Gan, E. S., Ooi, E. E.φ, and Ohh, M.φ Hypoxia and viral infectious diseases. JCI Insight 6(7), e147190 (2021).

Oshidari, R., Huang, R., Medghalchi, M., Tse, E. Y. W., Ashgriz, N., Lee, H. O., Wyatt, H., and Mekhail, K. DNA repair by Rad52 liquid droplets. Nat. Commun. 11, 695 (2020).

Kotwa JD, Jamal AJ, Mbareche H, Yip L, Aftanas P, Barati S, Bell NG, Bryce E, Coomes E, Crowl G, Duchaine C, Faheem A, Farooqi L, Hiebert R, Katz K, Khan S, Kozak R, Li AX, Mistry HP, Mozafarihashjin M, Nasir JA, Nirmalarajah K, Panousis EM, Paterson A, Plenderleith S, Powis J, Prost K, Schryer R, Taylor M, Veillette M, Wong T, Zoe Zhong X, McArthur AG, McGeer AJ, Mubareka S. Surface and Air Contamination With Severe Acute Respiratory Syndrome Coronavirus 2 From Hospitalized Coronavirus Disease 2019 Patients in Toronto, Canada, March-May 2020. J Infect Dis 2022;225(5):768-776.

Jamal AJ,* Mataseje LF,* Williams V, Leis JA, Tijet N, Zittermann S, Melano RG, Mulvey MR, Katz K, Allen VG, McGeer AJ. Genomic Epidemiology of Carbapenemase-Producing Enterobacterales at a Hospital System in Toronto, Ontario, Canada, 2007-2018. Antimicrob Agents Chemother 2021;65(8):e0036021. *contributed equally

Jamal AJ, Faheem A, Farooqi L, Zhong XZ, Armstrong I, Boyd DA, Borgundvaag E, Coleman B, Green K, Jayasinghe K, Johnstone J, Katz K, Kohler P, Li AX, Mataseje LF, Melano R, Muller MP, Mulvey M, Nayani S, Patel SN, Paterson A, Poutanen S, Rebbapragada A, Richardson D, Sarabia A, Shafinaz S, Simor AE, Willey BM, Wisely L, McGeer AJ. Household Transmission of Carbapenemase-Producing Enterobacterales (CPE) in Ontario, Canada. Clin Infect Dis 2021;73(11):e4607-e4615.

Jamal AJ, Pantelidis R, Sawicki R, Li AX, Chiu W, Morrison D, Marshman J, Baqi M, Richardson D, McGeer AJ, Borgia S. Standard versus combined chemical, mechanical, and  heat decontamination of hospital drains harboring carbapenemase-producing organisms (CPOs): a randomized controlled trial. Infect Control Hosp Epidemiol 2021;32(10):1275-1278.

Jamal AJ, Mozafarihashjin M, Coomes E, Anceva-Sami S, Barati S, Crowl G, Faheem A, Farooqi L, Kandel CE, Khan S, Li AX, Mistry H, Paterson A, Prost K, Plenderleith S, Prost K, Poutanen S, Powis J, Schryer R, Taylor M, Yip L, Zhong Z, McGeer AJ, Mubareka S. Sensitivity of midturbinate versus nasopharyngeal swabs for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Infect Control Hosp Epidemiol 2021;42(8):1001-1003.

Isho B,* Abe KT,* Zuo M,* Jamal AJ,* Rashod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yue FY, Marin LM, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, Mcgeer AJ, Gommerman JL, Gingras AC. Persistence of serum and saliva antibody response to SARS-CoV-2 spike antigens in COVID-19 patients. Sci Immunol 2020; 8(52):eabe5511. *contributed equally

Jamal AJ, Mozafarihashjin M, Coomes E, Powis J, Li AX, Paterson A, Anceva-Sami S, Barati S, Crowl G, Faheem A, Farooqi L, Khan S, Prost K, Poutanen S, Taylor M, Yip L, Zhong Z, McGeer AJ, Mubareka S. Sensitivity of nasopharyngeal swabs and saliva for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Clin Infect Dis 2021;72(6):1064-1066.

Jamal AJ, Mataseje LF, Brown KA, Katz K, Johnstone J, Muller MP, Allen VA, Borgia S, Boyd DA, Ciccotelli W, Delibasic K, Fisman DN, Khan N, Leis JA, Li AX, Mehta M, Ng W, Pantelidis R, Paterson A, Pikula G, Sawicki R, Schmidt S, Souto R, Tang L, Thomas C, McGeer AJ, Mulvey MR. Carbapenemase-producing Enterobacterales (CPE) in hospital drains in Southern Ontario, Canada. J Hosp Infect 2020; 106(4): 820-827.

Volling C, Ahangari N, Bartoszko JJ, Coleman BL, Jeldes FG, Jamal AJ, Johnstone J, Kandel C, Kohler P, Maltezou HC, dit Mieusement LM, McKenzie N, Mertz D, Monod A, Saeed S, She B, Stuart R, Thomas S, Uleryk E, McGeer A. Are sink drainage systems a reservoir for hospital-acquired Gammaproteobacteria colonization and infection? A systematic review. In press  Open Forum Infect Dis 2020 Dec 8;8(2):ofaa590.

Volling C, Thomas S, Johnstone J, Maltezou HC, Mertz D, Stuart R, Jamal AJ, Kandel C, Ahangari N, Coleman Bl, McGeer A. Development of a tool to assess evidence for causality in studies implicating sink drains as a reservoir for hospital-acquired gammaproteobacterial infection. J Hosp Infect 2020; 106(3):454-464.

Jamal AJ, Garcia-Jeldes, Baqi M, Borgia S, Johnstone J, Katz K, Kohler P, Muller MP, McGeer A on behalf of the Toronto Invasive Bacterial Diseases Network CPE Investigators. Infection Prevention and Control Practices Related to Enterobacteriaceae (CPE) in Acute Care Hospitals in Ontario, Canada. Infect Control Hosp Epidemiol 2019; 40(9): 1006-1012.

Ouyang B, Li LD, Mount J, Jamal AJ, Berry L, Simone C, Law M, Tai RM. Incidence and characteristics of needlestick injuries among medical trainees at a community teaching hospital: A cross-sectional study. J Occup Health 2017; 59(1): 63-73.

Jamal AJ, Resende MR, Prochnow T, et al. Simkania negevensis and acute cellular rejection in lung transplant recipients. Clinical Transplantation 2015; 29(8): 705-11.

Jamal AJ, Husain S, Li Y, Famure O, Kim SJ. Risk factors for late-onset cytomegalovirus infection or disease in kidney transplant recipients. Transplantation 2014; 97: 569-75.

Thai E, Murugan R, Binter Š, Burn Aschner C, Prieto K, Kassardjian A, Obraztsova AS, Kang RW, Flores-Garcia Y, Mathis-Torres S, Li K, Horn GQ, Huntwork RHC, Bolscher JM, de Bruijni MHC, Sauerwein R, Dennison SM, Tomaras GD, Zavala F, Kellam P, Wardemann H, Julien JP. Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Rep. 2023 Nov 28;42(11):113330. doi: 10.1016/j.celrep.2023.113330.

Kroch AE, O’Byrne P, Orser L, MacPherson P, O’Brien K, Light L, Kang RW, Nyambi A. Increased PrEP uptake and PrEP-RN coincide with decreased HIV diagnoses in men who have sex with men in Ottawa, Canada. Can Commun Dis Rep 2023;49(6):274–81 https://doi.org/10.14745/ccdr.v49i06a04 

Enenkel C, Kang RW, Wilfling F, Ernst OP. Intracellular localization of the proteasome in response to stress conditions. J Biol Chem. 2022 Jul;298(7):102083. doi: 10.1016/j.jbc.2022.102083.

Schieman, S., Mai, Q.D., Badawy, P.J., Kang, R.W. (2022). A forced vacation? The stress of being temporarily laid off during a global pandemic. Work and Occupations, 50(2), 255–283. https://doi.org/10.1177/07308884221129520 

Kao J, Paul Frankland. COVID fog demystified. Cell 2022; 14: 2391-2393.

Melliou S*, Sangster KT*, Kao J, Zarrei M, Lam KHB, Howe J, Papaioannou M-D, Tsang QPL, Borhani OA, Sajid RS, Bonnet C, Leheup B, Shannon S, Scherer S, Stavropoulos DJ, Djuric U, Diamandis P. Regionally defined proteomic profiles of human cerebral tissue and organoids reveal conserved molecular tenants of neurodevelopment. Cell Reports 2022.

Grenier K, Kao J, Diamandis P. Three-dimensional modeling of human neurodegeneration: brain organoids coming of age. Molecular Psychiatry 2020; 25: 254-274. https://www.nature.com/articles/s41380-019-0500-7 

Djuric U, Lam KHB, Kao J, Batruch I, Jevtic S, Papaioannou M-D, Diamandis P. Molecular and Cellular Proteomics 2019. 18(10): 2029-2043. https://pubmed.ncbi.nlm.nih.gov/31353322/ 

Papaioannou M-D, Djuric U, Kao J, Karimi S, Zadeh G, Aldape K, Diamandis P. Proteomic analysis of meningiomas reveals clinically distinct molecular patterns. Neuro-Oncology 2019; 21(8): 1028-1038. https://academic.oup.com/neuro-oncology/article/21/8/1028/5488088?login=true 

Karimi, R., Coupland, C.E., & Rubinstein, J.L. (2024). Vesicle Picker: A tool for efficient identification of membrane protein complexes in vesicles. Journal of Structural Biology 216, 108148. https://doi.org/10.1016/j.jsb.2024.108148

Coupland, C.E., Karimi, R., Bueler, S.A., Liang, Y., Courbon, G.M., Di Trani, J.M., Wong, C.J., Saghian, R., Youn, J.Y., Wang, L.Y. & Rubinstein, J.L. (2024). High-resolution electron cryomicroscopy of V-ATPase in native synaptic vesicles. Science, eadp5577. https://doi.org/10.1126/science.adp5577

Islas, P.*, Platnich, C.M.*, Gidi, Y., Karimi, R., Ginot, L., Cosa, G. & Sleiman, H. F. (2024). Automated synthesis of wireframe DNA nanotubes. Advanced Materials 36, 2403477. https://doi.org/10.1002/adma.202403477

Danby, P.M., Jeong, A., Sim, L., Sweeney, R.P., Wardman, J.F., Karimi, R., Geissner, A., Worrell, L.J., Strynadka, N.C.J., & Withers, S.G. (2023). Vinyl-halide modified unsaturated cyclitols are mechanism-based glycosidase inhibitors. Angewandte Chemie International Edition, 62.21 e202301258.

https://doi.org/10.1002/anie.202301258

Hoa, L.T., Golla, K., Karimi, R., Hughes, M.R., Lakschevitz, F., Cines, D.B., Kowalska, M.A., Poncz, M., McNagny, K.M., Häkkinen, L., & Kim, H. (2022). Platelet factor 4 (PF4/CXCL4) upregulates MMP-2 in gingival fibroblasts. Scientific Reports, 12, 18636.

https://doi.org/10.1038/s41598-022-19850-w

Van Kessel, A.T.M., Karimi, R., & Cosa, G. (2022). Live-cell imaging reveals impaired detoxification of lipid-derived electrophiles is a hallmark of ferroptosis. Chemical Science, 13, 9727-9738. https://doi.org/10.1039/D2SC00525E

Sweeney, R.P., Danby, P.M., Geissner, A., Karimi, R., Sim, L., Brask, J., and Withers, S.G. 2020. Development of an active site titration reagent for α-Amylases. Chemical Science, 12(2), 683–687.  https://doi.org/10.1039/D0SC05380E.

Dave, R., Randhawa, G., Kim, D., Simpson, M., & Hoare, T. (2022). Microgels and Nanogels for the Delivery of Poorly Water-Soluble Drugs. Molecular Pharmaceutics, 19(6), 1704–1721. https://doi.org/10.1021/acs.molpharmaceut.1c00967

Kim YK†, Ramalho-Santos M†. Hypertranscription: the invisible hand in stem cell biology. Stem Cell Reports 20(3), 103406 (2025)

Kim YK*, Collignon E*, Martin SB*, Ramalho-Santos M. Hypertranscription: the invisible hand in stem cell biology. Trends in Genetics 40(12), 1032-1046 (2024)

Zhu M, Gu B, Thomas EC, Huang Y, Kim YK, Tao H, Yung TH, Chen X, Zhang K, Woolaver EK, Nevin MR, Huang X, Winklbauer R, Rossant J, Sun Y, Hopyan S. A fibronectin gradient remodels mixed phase mesoderm. Science Advances 10(29), eadl636 (2024)

D’Cruz R, Kim YK, Mulder J, Ibeh N, Jiang N, Tian Y, Rosenblum ND. Hedgehog Signalling in Foxd1+ Embryonic Kidney Stromal Progenitors Controls Nephron Formation Via Cxcl12 and Wnt5a. Journal of Pathology 261(4), 385-400 (2023)

Kim YK†, Cho B, Cook DP, Tricka D, Wrana JL, Ramalho-Santos M†. Absolute Scaling of Single-Cell Transcriptomes Reveals Pervasive Hypertranscription in Adult Stem and Progenitor Cells. Cell Reports 42, 111987 (2023).

Bulut-Karslioglu A, Jin H, Kim YK, Cho B, Guzman-Ayala M, Williamson AJK, Hejna M, Stötzel M, Whetton AD, Song JS, Ramalho-Santos M. Chd1 protects genome integrity at promoters to sustain hypertranscription in embryonic stem cells. Nature Communications 12, 1–11 (2021).

Hayes K*, Kim YK*, Pera MF. A case for revisiting Nodal signaling in human pluripotent stem cells. Stem Cells 39, 1137–1144 (2021).

Rowan CJ, Li W, Martirosyan H, Erwood S, Hu D, Kim YK, Sheybani-Deloui S, Mulder J, Blake J, Chen L, Rosenblum ND. Hedgehog-GLI signaling in Foxd1-positive stromal cells promotes nephrogenesis via TGFβ signalling. Development 13, 145 (2018).

Kozlowski HN, Farkouh ME, Irwin MS, Radvanyi LG, Schimmer AD, Tabori U, Rosenblum ND. COVID-19: a pandemic experience that illuminates potential reforms to health research. EMBO Mol Med. 2020 Nov 6;12(11):e13278. doi: 10.15252/emmm.202013278. Epub 2020 Oct 19. PMID: 32996267; PMCID: PMC7536940.

Udugama, B*, Kadhiresan, P*, Kozlowski, HN*, Malekjahani, A*, Osborne, M*, Li, V*, Chen, H*, Mubareka, S, Gubbay, JB, & Chan, WCW (2020). Diagnosing COVID-19: The Disease and Tools for Detection. ACS nano, 14(4), 3822–3835. https://doi.org/10.1021/acsnano.0c02624

Mohamed MAA*, Kozlowski HN*, Kim J*, Zagorovsky K, Feld JJ, Mubareka S, Mazzulli T, Chan WCW. (2021). Diagnosing Antibiotic Resistance Using Nucleic Acid Enzymes and Gold Nanoparticles. ACS nano, 15(6), 9379–9390. https://doi.org/10.1021/acsnano.0c09902

Kozlowski HN, Mohamed MAA, Kim J, Bell NG, Zagorovsky K, Mubareka S, Chan WCW. (2021). A Colorimetric Test to Differentiate Patients Infected with Influenza from COVID-19. Small structures, 2100034. Advance online publication. https://doi.org/10.1002/sstr.202100034

Kozlowski HN, Sindhwani S, & Chan WCW. (2022). The Impact of Patient Characteristics on Diagnostic Test Performance. Small methods, 6(2), e2101233. https://doi.org/10.1002/smtd.202101233

Kozlowski, H. N*., Malekjahani, A.*, Li, V. Y. C., Lekuti, A. A., Perusini, S., Bell, N. G., Voisin, V., Pouyabahar, D., Pai, S., Bader, G. D., Mubareka, S., Gubbay, J. B., & Chan, W. C. W. (2023). Genotyping SARS-CoV-2 Variants Using Ratiometric Nucleic Acid Barcode Panels. Analytical chemistry, 95(14), 5877–5885. https://doi.org/10.1021/acs.analchem.2c04630

Kulandaimanuvel AntonyMichealraj, Sachin A.Kumar, Leo J.Y.Kim, Florence M.G.Cavalli, DavidPrzelicki, John B.Wojcik, AlbertoDelaidelli, AndreaBajic, OlivierSaulnier,  GrahamMacLeod, Ravi N.Vellanki, Maria C.Vladoiu, PaulGuilhamon, WinnieOng, John J.Y.Lee, YanqingJiang, Borja Holgado, AlexRasnitsyn, …Michael D.Taylor.  Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma. Cell. Volume 181, Issue 6, 11 June 2020, Pages 1329-1345.e24 https://www.cell.com/cell/fulltext/S0092-8674(20)30553-5

Suzuki, H., Kumar, S.A., Shuai, S. et al. Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma. Nature 574, 707–711 (2019). https://doi.org/10.1038/s41586-019-1650-0

Li NT*, Co IL*, Landon-Brace N, Latour S, McGuigan AP. Tissue-engineered 3D cancer microenvironment for screening therapeutics. In Kundu SC and Reis RL (Eds.) Biomaterials for 3D Tumor Modeling. 2020. Elsevier.

Chaudagar KK, Landon-Brace N, Solanki A, Hieromnimon HM, Hegermiller E, Li W, Shao Y, Joseph J, Wilkins DJ, Bynoe KM, Li XL, Clohessy JG, Ullas S, Karp JM, Patnaik A. Cabozantinib Unlocks Efficient In Vivo Targeted Delivery of Neutrophil-Loaded Nanoparticles into Murine Prostate Tumors. Mol Cancer Ther. 2021 Feb;20(2):438-449. doi: 10.1158/1535-7163.MCT-20-0167. Epub 2020 Dec 4. PMID: 33277441.

Landon-Brace N*, Cadavid JL*, Latour S, Co IL, Rodenhizer D, Li NT, Wu NC, Bugbee E, Chebotarev A, Zhang J, Wouters BG, McGuigan AP. An Engineered Patient-Derived Tumor Organoid Model That Can Be Disassembled to Study Cellular Responses in a Graded 3D Microenvironment. Adv Func Mat. 2021 Oct;31(41). doi: 10.1002/adfm.202105349

Steele C, Abbasi A, Islam SMA, Bowes A, Khandekar A, Haase K, Hames S, Ajayi D, Verfaillie A, Dhami P, McLatchie A, Lechner M, Light N, Shlien A, Malkin D, Feber A, Proszek P, Lesluyes T, Flanagan A, Mertens F, Tarabichi M, Van Loo P, Alexandrov L, Pillay N, Signatures of copy number alterations in human cancer. Nature July 2021.

Anderson N, Babichev Y, Fuligni F, Comitani F, Layeghifard M, Venier R, Maheshwari A, Guram S, Wunker C, Thompson JD, Zatzman M, Light N, Bernadini M, Wunder J, Andrulis I, Ferguson P, Razak AA, Swallow C, Al-Alwar R, Marcellus R, Rouzbahman M, Durocher D, Alexandrov L, Dickson B, Gladdy R, Shlien A. Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis, determining patient survival. Nature Communications 2021

Kim J*, Light N*, Subasri V*, Young E*, Wegman-Ostrosky T*, Barkauskas D, Hall D, Lupo P, Telfer F, Patidar R, Maese L, Shlien A, Skapek S, Wei JS, Wen X, Hawkins DS, Schiffman JD, Khan J, Malkin D, Stewart DR, Pathogenic Germline Variants in Cancer Susceptibility Genes in Children and Young Adults With Rhabdomyosarcoma. JCO Precision Oncology 2021 Jan 11; 75-87

Chung J, Maruvka YE, Sudhaman S, Kelly J, Haradhvala NJ, Bianchi V, Edwards M, Forster VJ, Nunes NM, Galati MA, Komosa M, Deshmukh S, Cabric V, Davidson S, Zatzman M, Light N, Hayes R, Brunga L, Anderson ND, Ho B, Hodel KP, Siddaway R, Morrissy AS, Bowers DC, Larouche V, Bronsema A, Osborn M, Cole KA, Opocher E, Mason G, Thomas GA, George B, Ziegler DS, Lindhorst S, Vanan M, Yalon-Oren M, Reddy AT, Massimino M, Tomboc P, Van Damme A, Lossos A, Durno C, Aronson M, Morgenstern DA, Bouffet E, Huang A, Taylor MD, Villani A, Malkin D, Hawkins CE, Pursell ZF, Shlien A, Kunkel TA, Getz G, Tabori U. DNA polymerase and mismatch repair exert distinct microsatellite instability signatures in normal and malignant human cells. Cancer Discov. 2020 Dec 18:CD-20-0790. doi: 10.1158/2159-8290.CD-20-0790. Epub ahead of print. PMID: 33355208.

Wang J, Merino DM, Light N, Murphy BL, Wang M, Guo X, Hodges A, Chau L, Liu K-W, Dhall G, Asgharzadeh S, Kiehna EN, Malkin D, Eison DW, VandenBerg SR, Eberhart CG, Sears RC, Roussel MF, Gilbertson RJ, Wechsler-Reya RJ, Myc and loss of p53 cooperate to drive formation of choroid plexus carcinoma. Cancer Research 2019 Mar 18; 10.1158/0008-5472.CAN-18-2565

Renzi S, Anderson N, Light N, Gupta A, Ewing-like sarcoma: An emerging family of round cell sarcomas. Journal of Cellular Physiology 2018 Sep 26;1-9.

Hodel KP*, de Borja R*, Henninger EE*, Campbell BB, Ungerleider N, Light N, Wu T, LeCompte KG, Göksenin AY, McBride C, Bunnell BA, Tabori U, Shlien A, Pursell ZF, Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair. eLife 2018 Feb 28; 7:e32692

Campbell BB*, Light N*, Fabrizio D, Zatzman M, de Borja R, Davidson S, Fuligni F, Edwards M, Elvin J, Hodel KP, Zahurancik WJ, Suo Z, Lipman T, Hussen K, Wimmer K, Kratz CP, Bowers DC, Laetsch TW, Dunn GP, Tanner J, Grimmer MR, Smirnov I, Larouche V, Samuel D, Bronsema A, Osborn M, Stearns D, Cole KA, Storm PB, Oren M, Opocher E, Mason G, Thomas GA, Sabel M, George B, Ziegler DS, Lindhorst S, Issai VM,  Constantini S, Toledano H, Elhasid R, Farah R, Dvir R, Dirks P, Huang A, Galati MA, Chung J, Ramaswamy V, Irwin MS, Aronson M, Durno C, Taylor MD, Rechavi G, Maris JM, Bouffet E, Hawkins C, Costello JF, Meyn MS, Pursell ZF, Malkin D, Tabori U, Shlien A, Comprehensive analysis of hypermutation in human cancer. Cell 2017 Nov 16; 171 (5), 1042-1056. e10

Adoue V, Schiavi A*, Light N*, Almlöf JC, Lundmark P, Ge B, Kwan T, Caron M, Rönnblom L, Wang C, Chen SH, Goodall AH, Cambien F, Deloukas P, Ouwehand WH, Syvänen AC, Pastinen T, Allelic expression mapping across cellular lineages to establish impact of non‐coding SNPs. Molecular Systems Biology 2014 Oct 17; 10 (10)

Light N*, Adoue V*, Ge B, Chen C, Kwan T, Pastinen T, Interrogation of allelic chromatin states in human cells by high-density ChIP-genotyping. Epigenetics 2014 Sep 7; 9 (9), 1238-1251.

Macklin JA, Djihanian N, Killackey T, MacIver J. 2019. Engaging Patients In Care (EPIC): a framework for heart function and heart transplant-specific patient engagement. Canadian Journal of Cardiology Open. 1; 43-46.

Dick SA*, Macklin JA*, Nejat S*, Clemente-Casares X, Momen A, Hossein S, Kantores C, Hosseinzadeh S, Barbu I, Chen J, Althagafi MG, Besla R, Wong A, Aronoff L, Zaman R, Lavine KJ, Razani B, Ginhoux F, Husain M, Cybulsky MI, Robbins CS, and Epelman S. 2019. Single cell RNA sequencing reveals a cardioprotective role for resident macrophages following myocardial infarction. Nature Immunology. 20; 29-39. (*equal contribution)

Mahendralingam MJ, Kim H, McCloskey CW, Aliar K, Casey AE, Tharmapalan P, Pellacani D, Ignatchenko V, Garcia-Valero M, Palomero L, Sinha A, Cruickshank J, Shetty R, Vellanki RN, Koritzinsky M, Stambolic V., Alam M, Schimmer AD, Berman HK, Eaves CJ, Pujana MA, Kislinger T & Khokha R. Mammary epithelial cells have lineage-rooted metabolic identities. Nature Metabolism 3, 665–681 (2021).

Kim H, Casey AE, Palomero L, Aliar K, Mahendralingam MJ, Parsons M, Narala S, Hui S, Bader GD, Mateo F, Hofer S, Waterhouse PD, Kislinger T, Pujana MA, Berman HK, Khokha R. (2021) Mammary lineage dictates homologous recombination repair and PARP inhibitor vulnerability. Nature Communications (Under Review).

Shanmugaraj A, Mahendralingam M, Gohal C, Horner N, Simunovic N, Musahl V, Samuelsson K, Ayeni OR. (2020). Press-fit fixation in anterior cruciate ligament reconstruction yields low graft failure and revision rates: a systematic review and meta-analysis. Knee Surgery, Sports Traumatology, Arthroscopy, 1-10.

Tharmapalan P, Mahendralingam M, Berman HK & Khokha R. (2019). Mammary stem cells and progenitors: targeting the roots of breast cancer for prevention. The EMBO Journal.

 Shehata M, Kim H, Vellanki R, Waterhouse PD, Mahendralingam M, Casey AE & Khokha R. (2019). Identifying the murine mammary cell target of metformin exposure. Communications Biology, 2(1), 192.

Pallegar NK, Garland CJ, Mahendralingam M, Viloria-Petit AM & Christian SL. (2019). A novel 3-dimensional co-culture method reveals a partial mesenchymal to epithelial transition in breast cancer cells induced by adipocytes. Journal of Mammary Gland Biology and Neoplasia, 24(1), 85-97.        

S. Majeed, C. Johnston, S. Saeedi, C. Mighton, V. Rokoszak, I. Abbasi, S. Grewal, V. Aguda, A. Kissoondoyal, D. Malkin, and Y. Bombard. International policies guiding the selection, analysis, and clinical management of secondary findings from genomic sequencing: a systematic review. Am J Hum Genet. 2024 Oct 3;111(10):2079-2093. doi: 10.1016/j.ajhg.2024.08.012. Epub 2024 Sep 18. PMID: 39299240; PMCID: PMC11480791.

S. Majeed*, D. Assamad*, V. Aguda, S*. Grewal, C. Butkowsky, M. Clausen, G. D’Amours and Y. Bombard. Digital Health Tools in Genomics: Advancing Diversity, Equity, and Inclusion. Public Health Genomics. 2023;26(1):194-200. doi: 10.1159/000534804. Epub 2023 Oct 26. PMID: 37883926.

* co-first authors

                                                                                                         
S. Majeed, C. Mighton, D. Malkin and Y. Bombard. Heath policy guiding the identification, analysis, and management of secondary findings for individuals undergoing genomic sequencing: a systematic review protocol. BMJ Open. 2022 Dec 22; 12(12):e065496. doi: 10.1136/bmjopen-2022-065496.

S. Majeed, MK. Aparnathi, KCJ. Nixon, V. Venkatasubramanian, F. Rahman, L. Song, J. Weiss, R. Barayan, V. Sugumar, SH. Barghout, JD. Pearson, R. Bremner, AD. Schimmer, MS. Tsao, G. Liu, BH. Lok. Targeting the ubiquitin-proteasome system using the UBA1 inhibitor TAK-243 is a potential therapeutic strategy for small cell lung cancer. Clin Cancer Res. 2022 Feb 14:clincanres.0344.2021. doi: 10.1158/1078-0432.CCR-21-0344. Epub ahead of print. PMID: 35165102.

T. Filler, D. Pieris, D. Teitelbaum, N. Chaya, S. Park, S. Majeed and L. Premji. Virtual breakout rooms: an effective approach to offer guidance to medical students on residency applications. Canadian Medical Education Journal. 2021 Aug 24.

        
K. Ottolino-Perry, A. Shahid, S. DeLuca, V. Son, M. Sukhram, F. Meng, Z. Liu, S. Rapic, N. Anantha, S. Wang, E. Chamma, C. Gibson, P. Medeiros, S. Majeed, A. Chu, O Wignall, A. Pizzolato, C. Rosen, L. Teene, D. Starr- Dunham, I. Kulbatski, T. Panzarella, S. Done, A. Easson, W. Leong, and R. DaCosta. Intraoperative fluorescence imaging with aminolevulinic acid detects grossly occult breast cancer: a phase II randomized controlled trial. Breast Cancer Research. 2021 Jul 12; 72, 1–20.
 

N. Khosravi, V. Mendes, G. Nirmal, S. Majeed, R.S. DaCosta, J.E. Davies. Intravital imaging for tracking of angiogenesis and cellular events around surgical bone implants. Tissue Eng. Part C Methods. 2018 Nov 15; 24, 617–627.
                                                 
E. Chamma, J. Qiu, L. Lindvere-Teene, K.M. Blackmore, S. Majeed, R. Weersink, C.I. Dickie, A.M. Griffin, J.S. Wunder, P.C. Ferguson, R.S. DaCosta. Optically-tracked handheld fluorescence imaging platform for monitoring skin response in the management of soft tissue sarcoma. J Biomed Opt. 2015 Jul 1;20(7):76011.
                                                 

Malkin EZ, Bratman SV. 2020. Bioactive DNA from extracellular vesicles and particles. Cell Death and Disease. 11(7), 584.

Malkin EZ, De Michino S, Lambie M, Gill R, Zhao Z, Rostami A, Arruda A, Minden MD, Bratman SC. 2022. Cell-free DNA topology depends on its subcellular and cellular origins in cancer. JCI Insight. 7(20), e159590.

Brooks PJ, Malkin EZ, De Michino S, Bratman SV. 2023. Isolation of salivary cell-free DNA for cancer detection. PLoS One. 18(5), e0285214.

Marvasti, T.B. Hoang, T.  Samanani, S. A case of bilateral painless vision loss as first presentation of neurosyphilis. In preparation for submission to CMAJ.

Marvasti, T.B. Alibhai, FJ. Li, SH. Wu, J. Yang, GJ. Cusimano, RJ. Ouzounian, M. Yau, T. Li, RK. Heart failure remodels the bone marrow stem and progenitor cell population and their response to myocardial repair. In preparation for submission to JAHA.

Marvasti, T.B. Alibhai, FJ. Li, SH. Wu, J. Cusimano, RJ. Ouzounian, M. Yau, T. Li, RK. Aging impairs human bone marrow function and cardiac repair following myocardial infarction in a humanized chimeric mouse. Aging Cell 2021

Alibhai, F. Lim, F. Yeganeh, A. DiStefano, P. Marvasti, T.B. Belfiore, A. Wlodarek, L. Gustafson, D. Millar, S. Li, S-H. Weisel, R. Fish, J. Li, R-K. Cellular senescence contributes to age-dependent changes in circulating extracellular vesicle cargo and function. Aging Cell 2020.

​​Wlodarek, L. Cao, F. Alibhai, F. Fekete, A. Noyan, N. Tobin, S. Marvasti, T.B. Wu, J. Li, S-H. Weisel, R. Wang, L. Jia, Z. Li, R-K. Rectification of radiotherapy-induced cognitive impairments in aged mice by reconstituted Sca-1+stem cells from young donors. Journal of Neuroinflammation 2020; 17:51.

Marvasti, T.B. Pietrobon, A. Updates from the Clinician Investigator Trainees of Canada. Clin Invest Med, 2020; 43 (1): E1-E4

Mirali, S. Fan, K. Cook, EK. Marvasti, T.B. Piloting a long distance clinician scientist trainee mentorship match in Canada. Clin Invest Med, 2020; 43 (1): E5-E8

Castanov, V. Zhou, T. Balestrini, C. Lefebvre, C. Cook, E. Whittaker, H. Macklin, J. Briard, J. Lazarte, J. Marvasti, T.B. Overview of the Canadian Clinician Investigator Trainees’ research presented at the 2019 CSCI-CITAC Joint Meeting. Clin Invest Med 2020; 43 (3): E5-14.

Pietrobon, A. Cook, E. Yin, C. Chan, D. Marvasti, T.B. International Training Considerations of Canadian Clinician-Scientist Trainees – A National Survey. Clin Invest Med 2020; 43(4):E2-7

Castanov, V. Ma, X. Pietrobon, A. Levit, A. Weber-Adrian, D. Lazarte, J. Sun, M. Ware, M. Steadman, P. Mirali, S. Marvasti, T.B. Cook, E. Scientific Overview on CSCI-CITAC Annual General Meeting and 2018 Young Investigators’ Forum. Clin Invest Med 2019; 42 (3): E6-13.

Seneviratne, AK. Zahr, SK. Mirali, S. Doshi, S. Marvasti, T. Civitarese, R. Rosenblum. Addressing the need for a new generation of  young translational researchers that focuses on societal impact: The Apollo Toronto Story. Clin Invest Med 2019; 42 (3): E14-16.

​​Barton KI, Ma X, Babadagli ME, Zhou E, Tonial N, Newell C, Ishaque A, Leduc-Pessah H, Marvasti TB, Mirali S, Levit A, Kumar S, Steadman PE, Cook EK, Abraham J. Scientific overview on CSCI-CITAC Annual General Meeting and 2017 Young Investigators' Forum. Clin Invest Med. 2018;41(3):E156-E164.

Marvasti, T. Moody, A. Singh, N. Maraj, T. Tyrrell, P. Afshin, M. Haptoglobin 2-2 Genotype is Associated with Presence and Progression of MRI Depicted Carotid Intraplaque Hemorrhage. International Journal of Cardiology, Heart and Vasculature. 2017.

Shaw, J. Cohen, A. Konforte, D. Marvasti, T. Colantonio, D.  Adeli, K. Validity of Establishing Pediatric Reference Intervals Based on Hospital Patient Data:  A Comparison of the Modified Hoffmann Approach to CALIPER Reference Intervals Obtained in Healthy Children. Journal of Clinical Biochemistry, 2014; 47 (3): 166-172

Marvasti, T. D’Alessandro, L.C.A. Manase, D. Papaz, T. Mital, S. Personalized Medicine in the Care of the Child with Congenital Heart Disease:  Discovery to Application. Journal of Congenital Heart Disease, 2013; 8 (3): 266-269

mazzoli

Shaw, J. Marvasti, T. Colantonio, D.  Adeli, K. Paediatric Reference Intervals: Challenges and Recent Initiatives. Journal of Critical Reviews in Clinical Laboratory Sciences, 2013; 50 (2): 37-50

Estey, M. Cohen A.H. Colantonio, D. Chan, M.K. Marvasti, T. Randell, E. Delvin, E. Cousineau, J. Grey, V. Greenway, D. Meng, Q,H. Jung, B.  Bhuiyan, J. Seccombe, D.  Adeli,K. CLSI-based Transference of the CALIPER Database of Pediatric Reference Intervals: Direct Validation Using Reference Samples from the CALIPER Cohort. Journal of Clinical Biochemistry, 2013; 46 (13): 1197-1219

Mazzoli V, Zhong LH, Dang VT, Shi Y, Werstuck GH; Characterization of Retinal Microvascular Complications and the Effects of Endoplasmic Reticulum Stress in Mouse Models of Diabetic Atherosclerosis. Invest. Ophthalmol. Vis. Sci. 2020;61(10):49.

Antonyshyn JA, Mazzoli V, McFadden MJ, Gramolini AO, Hofer SO, Simmons CA, Santerre JP. Mitigating the non-specific uptake of immunomagnetic microparticles enables the extraction of endothelium from human fat. Communications biology. 2021 Oct 20;4(1):1-5.

Balaghi, N., Erdemci,Tandogan, G.,McFaul, C.M and Fernandez-Gonzalez, R., 2023. Myosin waves and a mechanical asymmetry guide the oscillatory migration of Drosophila cardiac progenitors. Developmental Cell.

Chang, H., Bennet, A., Cameron, W., Au, A., McFaul, C.M., Yip, C. and Rocheleau, J. 2022. Targeting Apollo-NADP+ to image NADPH generation in pancreatic beta-cell organelles. ACS sensors, 7(11), 3308-3317.

Fernandez-Gonzalez, R., Balaghi, N., Wang, K., Hawkins, R., Rothenberg, K., McFaul, C., Schimmer, C., Ly, M., do Carmo, A.M., Scepanovic, G. and Erdemci-Tandogan, G. 2022. PyJAMAS: open-source, multimodal segmentation and analysis of microscopy images. Bioinformatics, 38(2), 594-596.

McFaul, C.M. and Fernandez-Gonzalez, R., 2017. Shape of my heart: cell-cell adhesion and cytoskeletal dynamics during Drosophila cardiac morphogenesis. Experimental Cell Research.

Guha, D., Alotaibi, N.M., Nguyen, N., Gupta, S.,McFaul, C. and Yang, V.X., 2017. Augmented Reality in Neurosurgery: A Review of Current Concepts and Emerging Applications. Canadian Journal of Neurological Sciences, pp.1-11.

Wang, M.F., Hunter, M.V., Wang, G., McFaul, C., Yip, C.M. and Fernandez-Gonzalez, R., 2017. Automated cell tracking identifies mechanically oriented cell divisions during Drosophila axis elongation. Development, 144(7), pp.1350-1361.

McQueen S, Jiang S, McParland A, Hammond Mobilio M, Moulton CA. Cognitive flow in health care settings: A systematic review. Med Educ. 2020 Dec 12. doi: 10.1111/medu.14435. Epub ahead of print. PMID: 33314200.

Wagner, N., McQueen, S. & Sonnadara, R.R. (2018) Bridging the gap: theoretical principles behind surgical boot camps. Boot Camp Approaches to Surgical Training. pp. 1-11. Basel, Switzerland: Springer. 2018.

Binesh Marvasti, T. & McQueen, S.A. (Co-Editors-in-Chief). Toronto Notes 2018. Toronto: Type & Graphics Inc. 2018. 

Acai, A., McQueen, S.A., McKinnon, V. & Sonnadara, R.R. (2017). Using art for the development of teamwork and communication skills among healthcare professionals: A literature review. Arts & Health. 9(1), 60-72.

Acai, A., McQueen, S.A., Fahim, C., Wagner, N., McKinnon, V., Boston, J., Maxwell, C., and Sonnadara, R.R. (2016). It’s not the form; it’s the process: a phenomenological study on the use of creative professional development workshops to improve teamwork and communication skills. Medical Humanities. 42(3), 173-180.

Nousiainen, M., McQueen, S.A., Hall, J., Kraemer, W., Ferguson, P., Marsh, L., Reznick, R., Reed, M.R. & Sonnadara, R. (In Press). Resident education in orthopaedic trauma: The future role of competency based medical education. The Bone and Joint Journal. 

McQueen, S.A., Petrisor, B., Bhandari, M., Fahim, C., McKinnon, V., and Sonnadara, R.R. (2016). Examining the barriers to meaningful assessment and feedback in medical training. The American Journal of Surgery. 211(2), 464-475.

Smith ECC*, Agarwal SM*, Panganiban KJ, Maksyutynska K, Monteiro JK, Lee J, Prasad F, Ji A, Shah D, Cavalier S, Prabhune RU, Radoncic E, Yang Z, Fuller K, McCarthy MJ, Prestwood TR, Ballon JS, Correll CU, Hahn MK, Freyberg Z. Antipsychotic drugs and dysregulated glucose homeostasis: A systematic review and meta-analysis. JAMA Psychiatry. 2025 August 27.

Monteiro JK, Miron VE. Microglia conduct the symphony of white matter degeneration in aging through T cell recruitment. Nature Neuroscience. 2025 May 22.

Hill BM*, Holloway RK*, Forbes L*, Davies C*, Monteiro JK, Brown CM, Rose J, Fudge N, Plant PL, Mahmood A, Arzamendi KB, Kent SA, Molina-Gonzalez I, Gyoneya S, Ransohoff RM, Wipke BT, Priller J, Schneider R, Moore CS, Miron VE. Monocytes reduce the efficiency of central nervous system remyelination. PLoS Biology. 2025 April 15.

Khan S, Shakeri A, Monteiro JK, Tariq S, Prasad A, Gu J, Filipe C, Li Y, Didar T. Comprehensive fluorescence profiles of contamination-prone foods applied to the design of microcontact-printed in situ functional oligonucleotide sensors. Scientific Reports. 2024 April 9.

Moinuddin A*, Poznanski SM*, Portillo AL*, Monteiro JK, Ashkar AA. Metabolic adaptations determine whether natural killer cells fail or thrive within the tumor microenvironment. Immunological Reviews. 2024 March 9.  

Balint E, Feng E, Giles EC, Ritchie TM, Qian AS, Vahedi F, Montemarano A, Portillo AL, Monteiro JK, Trigatti BL, Ashkar AA. Bystander activated CD8+ T cells mediate neuropathology during viral infection via antigen-independent cytotoxicity. Nature Communications. 2024 February 5. 15(1):896.

Lee J, Xue X, Au E, McIntyre WB, Asgariroozbehani R, Panganiban K, Tseng GC, Papoulias M, Smith E, Monteiro JK, Shah D, Cavalier S, Radoncic E, Prasad F, Agarwal SM, Mccullumsmith R, Freyberg Z, Logan RW, Hahn MK. Glucose dysregulation in antipsychotic-naive first-episode psychosis: in silico exploration of gene expression signatures. Translational Psychiatry. 2024 January 10. 14(1):19.

Portillo A, Monteiro JK, Rojas E, Ritchie T, Gillgrass A, Ashkar A. Charting a killer course towards the solid tumor: Developing novel tools to recruit and activate NK cells within the tumor. Frontiers in Immunology. 2023 November 8. 14:1286750.

Prasad A*, Khan S*, Monteiro JK, Li J, Arshad F, Ladouceur L, Tian L, Shakeri A, Li Y, Filipe C, Didar T. Actualizing in situ food monitoring through a smart lab-in-a-package system demonstrated by the detection of Salmonella in whole chicken. Advanced Materials. 2023 June 26. 2302641.

Khan S*, Monteiro JK*, Prasad A, Filipe CD, Li Y, Didar T. Material breakthroughs in smart food monitoring: Intelligent packaging and on-site testing technologies for spoilage and contamination detection. Advanced Materials. 2023 April 28. 2300875.

Feng E*, Monteiro JK*, Portillo A, Balint E, Ashkar A. Natural killer cells regulate macrophage-mediated hyperinflammation during viral infection. Journal of Infectious Diseases. 2023 March 30, jiad084.

Morgado, F., Vandewouw, M.M., Hammill, C. et al. Behaviour-correlated profiles of cerebellar-cerebral functional connectivity observed in independent neurodevelopmental disorder cohorts. Transl Psychiatry 14, 173 (2024). https://doi.org/10.1038/s41398-024-02857-4

 Kelly E, Meng F, Fujita H, Morgado F, Kazemi Y, Rice LC, Ren C, Escamilla CO, Gibson JM, Sajadi S, Pendry RJ, Tan T, Ellegood J, Basson MA, Blakely RD, Dindot SV, Golzio C, Khan MK, Katsanis N, Robins DM, Silverman JL, Singh KK, Wevrick R, Taylor MJ, Hammill C, Anagnostou E, Pfeiffer BE, Stoodley CJ, Lerch JP, du Lac S, Tsai PT. (2020) Regulation of autism-relevant behaviours by cerebellar-prefrontal cortical circuits. Nature Neuroscience. https://doi.org/10.1038/s41593-020-0665-z

Morgado F, Couch MJ, Stirrat E, Santyr G. (2018) Effect of T1 relaxation on ventilation mapping using hyperpolarized 129Xe multiple breath wash-out imaging. Magnetic Resonance in Medicine. DOI: 10.1002/mrm.27234 [Epub ahead of print]

Hrishikesh Suresh, Benjamin R Morgan, Karim Mithani, Nebras M Warsi, Han Yan, Jürgen Germann, Alexandre Boutet, Aaron Loh, Flavia Venetucci Gouveia, Julia Young, Jennifer Quon, Felipe Morgado, Jason Lerch, Andres M Lozano, Bassam Al-Fatly, Andrea A Kühn, Suzanne Laughlin, Michael C Dewan, Donald Mabbott, Carolina Gorodetsky, Ute Bartels, Annie Huang, Uri Tabori, James T Rutka, James M Drake, Abhaya V Kulkarni, Peter Dirks, Michael D Taylor, Vijay Ramaswamy, George M Ibrahim, Postoperative cerebellar mutism syndrome is an acquired autism-like network disturbance, Neuro-Oncology, Volume 26, Issue 5, May 2024, Pages 950–964, https://doi.org/10.1093/neuonc/noad230

Eder L, Mylvaganam S, Pardo Pardo J, Petkovic J, Strand V, Mease P, Colaco P. Sex-related differences in patient-characteristics and efficacy and safety of advanced therapies in randomized clinical trials in psoriatic arthritis: a systematic literature review and meta-analysis. Lancet Rheumatology. 2023 Nov 13; doi:10.1016/S2665-9913(23)00274-6.

Tokarz VL, Mylvaganam S, Klip A. Palmitate-induced insulin resistance causes actin filament stiffness and GLUT4 mis-sorting without altered Akt signaling. Journal of Cell Science. 2023 Oct 10:jcs.261300

Mylvaganam S and Freeman SA. The resolution of phagosomes. Immunological Reviews. 2023 Aug;00:1-20.

Tokarz VL, Pereira RVS, Jaldin-Fincati JR, Mylvaganam S, Klip A. Junctional integrity and directional mobility of lymphatic endothelial cell monolayers are disrupted by saturated fatty acids. Molecular Biology of the Cell. 2023 Apr 1;34(4):ar28.

Mylvaganam S, Plumb J, Yusuf B, Li R, Lu CY, Robinson LA, Freeman SA, Grinstein S. (in press). Endothelial integration of mechanosensory signals by the spectrin cytoskeleton. Nature Cell Biology. 2022 Aug; 24(8):1226-1238.

Leung G, Zhou Y, Ostrowski P, Mylvaganam S, Boroumand P, Guo C, Freeman SA, Muise AM. ARPC1B binds WASP to control actin polymerization and curtail tonic signaling in B cells. Journal of Clinical Investigation Insight. 2021 Dec 8;(23):e149376. doi:10.1172/jci.insight.149376.

Mylvaganam S, Freeman SA, Grinstein S. The cytoskeleton in phagocytosis and macropinocytosis. Current Biology. 2021 May; 31(10):R619-R632.

Mylvaganam S*, Earnshaw RE*, Heymann G*, Kalia SK, Kalia LV (in press). C-terminus of Hsp70 Interaction Protein (CHIP) and Neurodegeneration: Lessons from the Bench and Bedside. Current Neuropharmacology. 2021 Jan; 19(7):1038-1068.

Mylvaganam S, Riedl M, Vega A, Collins RF, Jaqaman K, Grinstein S, Freeman SA. Stabilization of endothelial receptor arrays by a polarized spectrin cytoskeleton facilitates rolling and adhesion of leukocytes. Cell Reports. 2020 Jun. 23;31(12):107798.

Freeman SA, Uderhardt S, Saric A, Collins RF, Buckley CM, Mylvaganam S, Boroumand P, Plumb J, Germain RN, Ren D, Grinstein S. Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance. Science. 2020 Jan; 367(6475):301-305.

Levin-Konigsberg R, Montano-Rendon F, Keren-Kaplan T, Li R, Ego B, Mylvaganam S, DiCiccio JE, Trimble WS, Bassik MC, Bonifacino JS, Fairn GD, Grinstein S. Phagolysosome resolution requires contacts with the endoplasmic reticulum and phosphatidylinositol-4-phosphate signaling. Nature Cell Biology. 2019 Oct;21(10):1234-1247.

Mylvaganam SM, Grinstein S, Freeman SA. Picket-fences in the plasma membrane: functions in immune cells and phagocytosis. Seminars in Immunopathology. 2018 Sep. doi: 10.1007/s00281-018-0705-x.

Song HM*, Mylvaganam SM*, Wang J, Mylvaganam SMK, Wu C, Carlen PL, Eubanks JH, Feng J, Zhang L. Contribution of the hippocampal CA3 circuitry to acute seizures and hyperexcitability response in mouse models of brain ischemia. Frontiers in Cellular Neuroscience. 2018 Aug; 12:278.

Stover KR, Lim S, Zhou TL, Stafford PM, Chow J, Li H, Sivanenthiran N, Mylvaganam S, Wu C, Weaver DF, Eubanks J, Zhang L. Susceptibility to hippocampal kindling seizures is increased in aging C57 black mice. IBRO reports. 2017 Dec; 3:33-44.

Vi L, Baht GS, Whetstone H, Ng A, Wei Q, Poor R, Mylvaganam S, Grynpas M, Alman BA. Macrophages promote osteoblastic differentiation in-vivo: implications in fracture repair and bone homeostasis. Journal of Bone and Mineral Research. 2015 Jun; 30(6):1090-102.

Ehrmann, D. E., Gallant, S. N., Nagaraj, S., Goodfellow, S. D., Eytan, D., Goldenberg, A., & Mazwi, M. L. (2022). Evaluating and reducing cognitive load should be a priority for machine learning in healthcare. Nature Medicine, 28(7), 1331–1333.

Goodday, S. M., Karlin, E., Alfarano, A., Brooks, A., Chapman, C., Desille, R., Rangwala, S., Karlin, D. R., Emami, H., Woods, N. F., Boch, A., Foschini, L., Wildman, M., Cormack, F., Taptiklis, N., Pratap, A., Ghassemi, M., Goldenberg, A., Nagaraj, S., … Friend, S. (2022). Correction: An Alternative to the Light Touch Digital Health Remote Study: The Stress and Recovery in Frontline COVID-19 Health Care Workers Study. JMIR Formative Research, 6(4), e38188.

Nagaraj, S., Gerych, W., Tonekaboni, S., Goldenberg, A., Ustun, B., & Hartvigsen, T. (2024). Learning from time series under temporal label noise. ArXiv, abs/2402.04398. https://doi.org/10.48550/arXiv.2402.04398

Nagaraj, S., Goodday, S., Hartvigsen, T., Boch, A., Garg, K., Gowda, S., Foschini, L., Ghassemi, M., Friend, S., & Goldenberg, A. (2023). Dissecting the heterogeneity of “in the wild” stress from multimodal sensor data. Npj Digital Medicine, 6(1), 237.

Nestor, B., Hunter, J., Kainkaryam, R., Drysdale, E., Inglis, J. B., Shapiro, A., Nagaraj, S., Ghassemi, M., Foschini, L., & Goldenberg, A. (2023). Machine learning COVID-19 detection from wearables. The Lancet. Digital Health, 5(4), e182–e184.

Singh, D., Nagaraj, S., Daniel, R., Flood, C., Kulik, D., Flook, R., Goldenberg, A., Brudno, M., & Stedman, I. (2023). The promises and challenges of clinical AI in community paediatric medicine. Paediatrics & Child Health, 28(4), 212–217.

Nagaraj S, Harish V, McCoy LG, Morgado F, Steadman I, Lu S, Drysdale E, Brudno M, Singh D. From Clinic to Computer and Back Again:  Practical Considerations When Designing and Implementing Machine Learning Solutions for Pediatrics. Current Treatment Options in Pediatrics. 2020 Sept; 6: 336-349. https://doi.org/10.1007/s40746-020-00205-4 

McCoy L, Nagaraj S, Morgado F, Harish V, Das S, Celi LA. What do medical students actually need to know about artificial intelligence? NPJ Digital Medicine. 2020 Jun; 3(1): 1-3. https://doi.org/10.1038/s41746-020-0294-7 

Singh D, Nagaraj S, Mashouri P, et al. Assessment of Machine Learning–Based Medical Directives to Expedite Care in Pediatric Emergency Medicine. JAMA Netw Open. 2022;5(3):e222599. doi:10.1001/jamanetworkopen.2022.2599

Goodday SM, Karlin E, Alfarano A, Brooks A, Chapman C, Desille R, Karlin DR, Emami H, Woods NF, Boch A, Foschini L, Wildman M, Cormack F, Taptiklis N, Pratap A, Ghassemi M, Goldenberg A, Nagaraj S, Walsh E, Stress And Recovery Participants, Friend S

An Alternative to the Light Touch Digital Health Remote Study: The Stress and Recovery in Frontline COVID-19 Health Care Workers Study. doi: 10.2196/32165

Ehrmann, D.E., Gallant, S.N., Nagaraj, S. et al. Evaluating and reducing cognitive load should be a priority for machine learning in healthcare. Nature Medicine 28, 1331–1333 (2022). https://doi.org/10.1038/s41591-022-01833-z

S. D. Goodfellow, D Shubin, RW Greer, S Nagaraj, et al., "Rhythm Classification of 12-Lead ECGs Using Deep Neural Networks and Class-Activation Maps for Improved Explainability," 2020 Computing in Cardiology, 2020, pp. 1-4, doi: 10.22489/CinC.2020.353.

Hassan S, Nesovic K, Babineau J, Furlan AD, Kumbhare D, Carlesso LC. Identifying chronic low back pain phenotypic domains and characteristics accounting for individual variation: a systematic review. Pain. 2023 Oct 1;164(10):2148-90. DOI: 10.1097/j.pain.0000000000002911

Koh RG, Khan MA, Rashidiani S, Hassan S, Tucci V, Liu T, Nesovic K, Kumbhare D, Doyle TE. Check It Before You Wreck It: A Guide to STAR-ML for Screening Machine Learning Reporting in Research. IEEE Access. 2023 Sep 15.

DOI: 10.1109/ACCESS.2023.3316019

Koh RG, Paul TM, Nesovic K, West D, Kumbhare D, Wilson RD. Reliability and minimal detectable difference of pressure pain thresholds in a pain-free population. British Journal of Pain. 2023 Jun;17(3):239-43.

https://doi.org/10.1177/20494637221147185

Nesovic K, Koh RG, Sereshki AA, Zadeh FS, Popovic MR, Kumbhare D. Ultrasound image quality evaluation using a structural similarity based autoencoder. In2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) 2021 Nov 1 (pp. 4002-4005). IEEE. DOI: 10.1109/EMBC46164.2021.9630261.

Fulford AD, Enderle L, Rusch J, Hodzic D, Holder MV, Earl A, Oh RH, Tapon N, McNeill H. Expanded directly binds conserved regions of Fat to restrain growth via the Hippo pathway. J Cell Biol.; 2023 May 1;222(5):e202204059. doi: 10.1083/jcb.202204059.

Lü Y, Cho T, Mukherjee S, Suarez CF, Gonzalez-Foutel NS, Malik A, Martinez S, Dervovic D, Oh RH, Langille E, Al-Zahrani KN, Hoeg L, Lin ZY, Tsai R, Mbamalu G, Rotter V, Ashton-Prolla P, Moffat J, Chemes LB, Gingras AC, Oren M, Durocher D, Schramek D. Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability. Mol Syst Biol.; 2024 Jun;20(6):719-740. doi: 10.1038/s44320-024-00032-x.

Langille E, Al-Zahrani KN, Ma Z, Liang M, Uuskula-Reimand L, Espin R, Teng K, Malik A, Bergholtz H, Ghamrasni SE, Afiuni-Zadeh S, Tsai R, Alvi S, Elia A, Lü Y, Oh RH, Kozma KJ, Trcka D, Narimatsu M, Liu JC, Nguyen T, Barutcu S, Loganathan SK, Bremner R, Bader GD, Egan SE, Cescon DW, Sørlie T, Wrana JL, Jackson HW, Wilson MD, Witkiewicz AK, Knudsen ES, Pujana MA, Wahl GM, Schramek D. Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer. Cancer Discov.; 2022 Dec 2;12(12):2930-2953. doi: 10.1158/2159-8290.CD-21-0865.

Loganathan SK, Schleicher K, Malik A, Quevedo R, Langille E, Teng K, Oh RH, Rathod B, Tsai R, Samavarchi-Tehrani P, Pugh TJ, Gingras AC, Schramek D. Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling. Science; 2020 Mar 13;367(6483):1264-1269. doi: 10.1126/science.aax0902.

Martchenko A, Oh RH, Wheeler SE, Gurges P, Chalmers JA, Brubaker PL. Suppression of circadian secretion of glucagon-like peptide-1 by the saturated fatty acid, palmitate. Acta Physiol (Oxf).; 2018 Apr;222(4):e13007. doi: 10.1111/apha.13007.

Uusküla-Reimand L, Lee CA., Oh RH, Klein ZP, Adler N, Alvi SA, Langille E, Pasini E, Cheng KCL, Abd-Rabbo D, Hou H, Tsai R, Bhat M, Schramek D, Wilson MD, Reimand J

bioRxiv; 2024.11.06.622320; doi: https://doi.org/10.1101/2024.11.06.622320

Lin ZP, Nguyen MLN, Ouyang B, MacMillan P, Ngai J, Kingston BR, Chan WCW. Macrophages actively transport nanoparticles in tumours after extravasation, in press.

Ouyang B, Kingston BR, Poon W, Zhang YN, Lin ZP, Syed AM, Couture- Sen ́ecal J, Chan WCW. Impact of tumour barriers on nanoparticle delivery to macrophages. Molecular Pharmaceutics, in press.

Kingston BR, Lin ZP, Ouyang B, MacMillan P, Ngai J, Syed AM, Sindhwani S, Chan WCW. Specific endothelial cells govern nanoparticle entry into solid tumours. ACS Nano, 2021, 15(9):14080-14094.

Poon W, Kingston BR, Ouyang B, Ngo W, Chan WCW. A blueprint for designing nanoparticle systems (Review). Nature Nanotechnology; 2020, 15(10):819-829.

Ouyang B, Poon W, Zhang YN, Lin ZP, Kingston BR, Syed AM, Tavares AJ, Zhang Y, Chen J, Valic MS, MacMillan P, Couture-Senécal J, Zheng G, Chan WCW. The dose threshold for nanoparticle tumour delivery. Nature Materials; 2020, 19:1362-1371.

Liu LY, Ma XZ, Ouyang B, Ings D, Marwah S, Liu J, Chen A, Gupta R, Manuel J, Gage BK, Cirlan J, Khuu N, Chung S, Camat D, Cheng M, Sekhon M, Zagorovsky K, Thoeni C, Adeyi O, Fischer S, Echeverri J, Kollmann D, Keller G, Bader GD, Chan WCW, Michalak TI, McGilvray ID, MacParland SA, Tracking nanoparticle uptake in a spontaneous and immunocompetent woodchuck liver tumour model. ACS Nano; 2020, 14(4):4698-4715.

Syed A; MacMillan P; Ngai J; Wilhelm S; Sindhwani S; Kingston B; Wu J; Llano-Suarez P; Lin Z; Ouyang B; Kahiel Z; Gadde SS, Chan WCW; Liposome Imaging in Optically Cleared Tissues. Nano Letters; 2020, 20(2):1362-1369.

Sindhwani S, Syed A, Ngai J, Kingston B, Maiorino L, Rothschild J, MacMillan P, Zhang Y, Unni N, Hoang T, Wu J, Wilhelm S, Zilman A, Gadde S, Sulaiman A, Wang L, Ouyang B, Lin ZP, Egeblad M, Chan WCW, The entry of nanoparticles into solid tumours. Nature Materials; 2020, 19(5):566-575.

Zhang YN, Ouyang B*, Poon W*, Lazarovits J*, Nguyen LNM, Kingston BR, Chan WCW. Nanoparticle size determines antigen retention and presentation in lymph node follicles for humoral immunity. Nano Letters; 2019, 19(10):7226- 7235.

Glancy D, Zhang Y, Wu JLY, Ouyang B, Ohta S, Chan WCW. Character- izing the protein corona of sub-10 nm nanoparticles. Journal of Controlled Release; 2019, 304:102-110.

Poon W, Ouyang B*, Zhang YN*, Kingston BR, Wu JLY, Wilhelm S, Chan WCW. Elimination Pathways of Nanoparticles. ACS Nano; 2019, 13(5):5785- 5798.

Tavares AJ, Poon W, Zhang YN, Dai Q, Besla R, Ding D, Ouyang B, Li A, Chen J, Zheng G, Robbins C, Chan WCW. The effect of removing Kupffer cells on nanoparticle tumour delivery. Proceedings of the National Academy of Science; 2017, E10871-E10880.

MacParland SA, Tsoi KM, Ouyang B, Ma XZ, Manuel J, Fawaz A, Ostrowski MA, Alman BA, Zilman A, Chan WC, McGilvray ID. Gold Nanoparticle Uptake by Human Derived Macrophages and Primary Liver Phagocytic Cells is Dependent on Phenotype. ACS Nano; 2016, 11(3):2428-2443.

Tsoi KM, MacParland SA, Ma XZ, Spetzler VN, Echeverri J, Ouyang B, Fadel SM, Sykes EA, Goldaracena N, Kaths JM, Conneely JB, Alman BA, Selzner M, Ostrowski MA, Adeyi OA, Zilman A, McGilvray ID, Chan WCW. Clearance of hard nanomaterials by the liver: a mechanistic study. Nature Materials; 2016, 15:1212-1221.

Ouyang B, Li LD, Mount J, Jamal AJ, Berry L, Simone C, Law M, Tai RM. Incidence and Characteristics of Needlestick Injuries among Medical Trainees at a Community Teaching Hospital: A Cross-Sectional Study. Journal of Occupational Health. 2016 Nov 22:15-0253.

Jones AA, Ng E, Deguise MO, Mak L, Ouyang B, Sivapragasam M, MacNairn IA, Narth S, Benesch MG, Forrest L, Wang X. MD/PhD Training in Canada: Results from a national trainee and program director review. Clinical and investigative medicine. Médecine clinique et experimentale. 2016 Sep 11;39(4):E132.

Ouyang B. The Resistance to Antisepsis in the 19th Century: A Briefing on Two European Antisepsis Proponents. (2015). University of Toronto Medical Journal; 92(3):92-94.

Franz KS, Patel K, Kilkenny DM. A biomedical Engineering Laboratory module for exploring involuntary muscle reflexes using Electromyography. J Biol Eng. 2020 Nov 9;14(1):26. doi: 10.1186/s13036-020-00248-z. PMID: 33292462; PMCID: PMC7650172.

Katz CN*, Patel K*, Talakoub O, Groppe D, Hoffman K, Valiante TA. Differential Generation of Saccade, Fixation, and Image-Onset Event-Related Potentials in the Human Mesial Temporal Lobe. Cereb Cortex. 2020 Sep 3;30(10):5502-5516. doi: 10.1093/cercor/bhaa132. PMID: 32494805; PMCID: PMC7472212.

Rafiee M, Patel K, Groppe DM, Andrade DM, Bercovici E, Bui E, Carlen PL, Reid A, Tai P, Weaver D, Wennberg R, Valiante TA. Daily listening to Mozart reduces seizures in individuals with epilepsy: A randomized control study. Epilepsia Open. 2020 May 27;5(2):285-294. doi: 10.1002/epi4.12400. PMID: 32524054; PMCID: PMC7278546.

Patel, K., Katz, C. N., Kalia, S. K., Popovic, M. R. & Valiante, T. A. Volitional control of individual neurons in the human brain. Brain (2021). doi:10.1093/brain/awab370

Patel, K.*, Katz, C.N.*, Duncan, K. D. & Valiante, T. A. Developing a Neuroprosthesis for Memory : The Past, Present and Future. in Handbook of Neuroengineering (ed. Thakor, N. V.) 1–53 (Springer, Singapore, 2021). doi:https://doi.org/10.1007/978-981-15-2848-4_64-2 

Patel K, Milosevic M, Nakazawa K, Popovic MR, Masani K. Wheelchair Neuroprosthesis for Improving Dynamic Trunk Stability. IEEE Trans Neural Syst Rehabil Eng. 2017 Dec;25(12):2472-2479. doi: 10.1109/TNSRE.2017.2727072. Epub 2017 Jul 14. PMID: 28715333.

Postill G, Murray R, Wilton AS, Wells RA, Sirbu R, Daley MJ, Rosella L. The Use of Cremation Data for Timely Mortality Surveillance During the COVID-19 Pandemic in Ontario, Canada: Validation Study JMIR Public Health Surveill 2022;8(2):e32426  doi: 10.2196/32426

Postill G, Adams CL, Zanin C, Halpin M, Ritter C. Adherence of those at low risk of disease to public health measures during the COVID-19 pandemic: A qualitative study. Jasny LS, editor. PLoS ONE 2022 Oct 25;17(10):e0276746. doi: 10.1371/journal.pone.0276746

Postill G, Halpin M, Zanin C, Ritter, C. ‘I’ve never been so stressed in my life’: a qualitative analysis of young adults’ lived experience amidst pandemic restrictions in Prince Edward Island, Canada. BMJ Open 2024;14:e075567. doi: 10.1136/bmjopen-2023-075567

Postill, G. Itanyi, I.U., Kuenzig, M.E. Tang, A., Harish, V., Buajitti, E., Rosella, L., Benchimol, E.I. “Machine learning prediction of premature death from multimorbidity among people with inflammatory bowel disease: a population-based retrospective cohort study.” CMAJ Mar 2025, 197 (11) E286-E297; DOI: 10.1503/cmaj.241117

Colacci M, Huang YQ, Postill G, Zhelnov P, Fennelly O, Verma A, Straus S, Tricco AC. Sociodemographic bias in clinical machine learning models: a scoping review of algorithmic bias instances and mechanisms. J Clin Epidemiol. 2025 Feb;178:111606. doi: 10.1016/j.jclinepi.2024.111606.

 Profant, M.*, Lee, J.W.*, and Wang, C. (2022). Metabolic Sex Dimorphism of the Brain at the Gene, Cell, and Tissue Level. J.I. 208, 212–220. https://doi.org/10.4049/jimmunol.2100853.

Wasén, C., Simonsen, E., Ekwudo, M.N., Profant, M.R., and Cox, L.M. (2022). The emerging role of the microbiome in Alzheimer’s disease. In International Review of Neurobiology (Elsevier), p. S0074774222000927. 10.1016/bs.irn.2022.09.001.

Psarianos P., Kwan Y-Y J., Dell S., Wee B. W., Rey-McIntyre K., Chen H., Dissanayake D., Laxer M. R., Shum A., Liu F-F., Yip W. K. COPA Syndrome (Ala239Pro) Presenting with Isolated Follicular Bronchiolitis in Early Childhood: Case Report. J Clin Immunol 2021 Oct;41(7):1660-1663.

Zhao, X., Psarianos, P., Ghoraie, L., Yip, K., Goldstein, D., Gilbert, R., Witterick, I., Pang, H., Hussain, A., Lee, J., Williams, J., Bratman, S., Ailles, L., Haibe-Kains, B., Liu, F-F. Metabolic regulation of dermal fibroblasts contributes to skin extracellular matrix homeostasis and fibrosis. Nature Metabolism 1, 147-157 (2019). https://doi.org/10.1038/s42255-018-0008-5

Kwan, J., Psarianos, P., Bruce, J., Yip, K., Liu, F-F. The complexity of microRNAs in human cancer, Journal of Radiation Research, Volume 57, Issue S1, August 2016, Pages i106–i111, https://doi.org/10.1093/jrr/rrw009 

Bralha F. N., Liyanage S. U., Hurren R., Wang X., Hi Son M., Fung T. A., Chingcuanco F. B., Tung A. Y. W., Andreazza A. C., Psarianos P., Schimmer A. D., Salmena L., Laposa R. R. et al Targeting mitochondrial RNA polymerase in acute myeloid leukemia. Oncotarget. 2015; 6: 37216-37228.

Rahman, A., DeYoung, T., Cahill, L.S., Yee, Y., Debebe, S.K., Botelho, O., Seed, M., Chaturvedi, R.R. and Sled, J.G., 2021. A mouse model of hypoplastic left heart syndrome demonstrating left heart hypoplasia and retrograde aortic arch flow. Disease models & mechanisms, 14(11), p.dmm049077.

Rahman, A., Zhou, Y.Q., Yee, Y., Dazai, J., Cahill, L.S., Kingdom, J., Macgowan, C.K. and Sled, J.G., 2017. Ultrasound detection of altered placental vascular morphology based on hemodynamic pulse wave reflection. American Journal of Physiology-Heart and Circulatory Physiology, 312(5), pp.H1021-H1029.

Rahman, A., Cahill, L.S., Zhou, Y.Q., Hoggarth, J., Rennie, M.Y., Seed, M., Macgowan, C.K., Adamson, S.L. and Sled, J.G., 2017. A mouse model of antepartum stillbirth. American Journal of Obstetrics & Gynecology, 217(4), pp.443-e1.

Saghian, R., Cahill, L.S., Rahman, A., Steinman, J., Stortz, G., Kingdom, J., Macgowan, C.K. and Sled, J.G., 2021. Interpretation of wave reflections in the umbilical arterial segment of the feto-placental circulation: computational modeling of the feto-placental arterial tree. IEEE Transactions on Biomedical Engineering, 68(12), pp.3647-3658.

Cahill, L.S., Stortz, G., Chandran, A.R., Milligan, N., Shinar, S., Whitehead, C.L., Hobson, S.R., Ayyathurai, V., Rahman, A., Saghian, R. and Jobst, K.J., 2021. Wave reflections in the umbilical artery measured by Doppler ultrasound as a novel predictor of placental pathology. EBioMedicine, 67, p.103326.

Cahill, L.S., Shinar, S., Whitehead, C.L., Hobson, S.R., Stortz, G., Ayyathurai, V., Chandran, A.R., Rahman, A., Kingdom, J.C., Baschat, A. and Murphy, K.E., 2021. Sex differences in modulation of fetoplacental vascular resistance in growth-restricted mouse fetuses following betamethasone administration: comparisons with human fetuses. American journal of obstetrics & gynecology MFM, 3(1), p.100251.

Cahill, L.S., Zhou, Y.Q., Hoggarth, J., Yu, L.X., Rahman, A., Stortz, G., Whitehead, C.L., Baschat, A., Kingdom, J.C., Macgowan, C.K. and Serghides, L., 2019. Placental vascular abnormalities in the mouse alters umbilical artery wave reflections. American Journal of Physiology-Heart and Circulatory Physiology.

Cahill, L.S., Rennie, M.Y., Hoggarth, J., Yu, L.X., Rahman, A., Kingdom, J.C., Seed, M., Macgowan, C.K. and Sled, J.G., 2017. Feto‐and utero‐placental vascular adaptations to chronic maternal hypoxia in the mouse. The Journal of physiology.

Rennie, M. Y., Rahman, A., Whiteley, K. J., Sled, J. G., & Adamson, S. L. (2015). Site-specific increases in utero-and fetoplacental arterial vascular resistance in eNOS-deficient mice due to impaired arterial enlargement. Biology of reproduction, 92(2), 48.

Kwon N., Weng H., Rajora M.A.*, Zheng G.* Activatable photosensitizers: From fundamental principles to advanced designs. Angewandte Chemie (2025): e202423348.

Rajora M.A., Leung C., Chen J., and Zheng G. Fabricating and labeling microbubbles with fluorescent and radioactive tracers. Journal of Visualized Experiments (2025); 215: e67431.

Dhaliwal A., Ma J., Zheng M., Lyu Q., Rajora M.A., Ma S., Olivia L., Ku A., Valic M., Wang B. and Zheng G. Deep learning for automatic organ and tumor segmentation in nanomedicine pharmacokinetics. Theranostics (2024); 14: 973-987.

Rajora M.A.*, Dhaliwal A.*, Zheng M., Choi V., Overchuk M., Lou J., Pellow C., Goertz D., Chen J. and Zheng G. Quantitative pharmacokinetics reveal impact of lipid composition on microbubble and nanoprogeny shell fate. Advanced Science (2024); 11: 2304453.

Walsh C.*, Rajora M.A.*, Ding L., Nakamura S., Endisha H., Rockel J., Chen J., Kapoor M., and Zheng G. Protease-activatable porphyrin molecular beacon for osteoarthritis management. Chemical & Biomedical Imaging (2023); 1: 1; 66-80. Awarded ACS Editor’s Choice.

Cheng M.H.Y., Cevallos A., Rajora M.A., and Zheng G. Fast, facile, base-free microwave-assisted metallation of bacteriochlorophylls and corresponding high yield synthesis of TOOKAD. Journal of Porphyrins and Phthalocyanines (2021); Online ahead of print; doi: 10.1021/acs.molpharmaceut.1c00819

Ikeda J*, Scipione C.A.*, Hyduk S., Althagafi M.G., Atif J., Dick S.A., Rajora M.A., Jang E., Emoto T., Murakami J., Ikeda N., Ibrahim H.M., Polenz C.K., Gao X., Tai K., Jongstra-Bilen J., Nakashima R., Epelman S., Robbins C., Zheng G., Lee W., MacParland S.A., and Cybulsky M.I. Radiation Impacts Early Atherosclerosis by Suppressing Intimal LDL Accumulation. Circulation Research (2021); 128: 530-543.

Overchuk M., Harmatys K.M., Sindhwani S., Rajora M.A., Koebel A., Charron D.M., Syed A.M., Chen J., Pomper M.G., Wilson B.C., Chan W.C.W. and Zheng G. Subtherapeutic photodynamic treatment facilitates tumor nanomedicine delivery and overcomes desmoplasia. Nano Letters (2021); 21: 344-352.

Choi V.*, Rajora M.A.*  and Zheng G. Activating drugs with sound: Mechanisms behind sonodynamic therapy and the role of nanomedicine. Bioconjugate Chemistry (2020); 31: 967-989. Associated supplemental cover art.

Charron D., Yousefalizadeh G., Buzza H.H., Rajora M.A., Chen J., Stamplecoskie K.G. and Zheng G. Photophysics of J-aggregating porphyrin-lipid photosensitizers in liposomes: Impact of lipid saturation. Langmuir (2020); 36: 5385-5393.

Overchuk M., Zheng M., Rajora M.A., Charron D.M., Chen J. and Zheng G. Tailoring porphyrin conjugation for nanoassembly-driven phototheranostic properties. ACS Nano (2019); 13: 4560-4571.

Rajora M.A., Lou J. and Zheng G. Advancing the biomedical utility of porphyrins via supramolecular chemistry. Chemistry Society Reviews (2017); 46: 6433-6469. Associated back cover art.

Rajora M.A., Ding L., Valic M., Jiang W., Overchuk M., Chen J. and Zheng G. Tailored theranostic apolipoprotein E3 porphyrin-lipid nanoparticles target glioblastoma. Chemical Science (2017); 8: 5371-5384.

Rajora M.A. and Zheng G. Targeting SR-BI for Cancer Diagnostics, Imaging and Therapy. Frontiers in Pharmacology (2016); 7: 326.

Huynh E., Rajora M.A. and Zheng G. Multimodal micro, nano and size conversion ultrasound agents for imaging and therapy. Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology (2016); 8: 796. Associated front cover art.

Parker G, Rappon T, Berta W (2019). Active change interventions to de-implement low-value healthcare practices: a scoping review protocol. BMJ Open 2019:9;e027370.

Shahid N, Rappon T, Berta W (2019). Applications of artificial neural networks in health care organizational decision-making: a scoping review. PLoS ONE 14(2):e0212356.

Shah, P.T., Valiante, T.A., and Packer, A.M. (2024). Highly local activation of inhibition at the seizure wavefront in vivo. Cell Reports 43.

Sacher, W.D., Chen, F.-D., Moradi-Chameh, H., Luo, X., Fomenko, A., Shah, P.T., Lordello, T., Liu, X., Almog, I.F., Straguzzi, J.N., et al. (2021). Implantable photonic neural probes for light-sheet fluorescence brain imaging. Neurophotonics 8, 025003.

Nachmias B, Khan DH, Voisin V, Mer AS, Thomas GE, Segev N, St-Germain J, Hurren R, Gronda M, Botham A, Wang X, MacLean N, Seneviratne AK, Duong N, Xu C, Arruda A, Orouji E, Algouneh A, Hakem R, Shlush L, Minden MD, Raught B, Bader GD, Schimmer AD. IPO11 Regulates the Nuclear Import of BZW1/2 and is Necessary for AML Cells and Stem Cells. Leukemia. February 12th, 2022. DOI: 10.1038/s41375-022-01513-4.

Schimmer AD, Singh RP, Seneviratne AK, Thomas G, MacLean N, Hurren R. Transduction of Primary AML Cells with Lentiviral Vector for In Vitro Study or In Vivo Engraftment. STAR protocols. December, 2020. doi: https://doi.org/10.1016/j.xpro.2020.100163.

Seneviratne AK, Wright C, Lam W, Lipton JH, Michelis FV. Comorbidity Profile of Survivors at 20 Years Following Allogeneic Hematopoietic Cell Transplantation. European Journal of Haematology, November 11th, 2020. 00:1–9. https://doi.org/10.1111/ejh.13542.

Khan D, Mullokandoy M, Wu Y, Voisin V, Gronda M, Hurren R, Wang X, MacLean N, Jeyaraju D, Jitkova J, Xu W, Laister R, Seneviratne AK, Blatman Z, Ketela T, Bader G, Minden M, Grosa A, Schimmer AD. Mitochondrial carrier homolog 2 (MTCH2) regulates the differentiation of AML cells by controlling pyruvate entry into the mitochondria, nuclear localization of pyruvate dehydrogenase complex and H3 and H4 histone acetylation. Blood. April, 2020. doi: 10.1182/blood.2019000106.

Singh RP, Jeyaraju DV, Voisin V, Xu C, Hawley JR, Seneviratne AK, Barghout SH, Khan D, Hurren R, Gronda M, Wang X, Jitkova Y, Sharon D, Liyanagae S, MacLean N, Soriano J, Minden MD, Chan SM, Bader GD, Lupien M, Schimmer AD.

Mitochondrial copper regulates AML stemness and differentiation by modulating chromatin accessibility. Cell Stem Cell, March 2020. 26(6): 926-937.e10

Seneviratne AK, Zahr SK, Mirali S, Doshi S, Binesh Marvasti T, Civitarese R, Rosenblum ND. Addressing the need for a new generation of young translational researchers that focuses on societal impact: The Apollo Toronto Story. Clinical and Investigative Medicine. September 2019. 42(3): E14-16.

Xu M, Seneviratne AK, Schimmer AD. Phospholipid metabolism regulates AML growth and stemness. Aging. June, 2019. 11(12):3895-3897.

Seneviratne AK, Xu M, Schimmer AD. Tafazzin modulates cellular phospholipid composition to regulate AML stemness. Molecular & Cellular Oncology. June, 2019. 6(5): e1620051

Seneviratne AK*, Xu M*, Aristizabal Henao JJ, Fajardo VA, Hao Z, Voisin V, Xu GW, Hurren R, Kim S, MacLean N, Wang X, Gronda M, Jeyaraju D, Jitkova Y, Ketela T, Mullokandov M, Sharon D, Thomas G, Chouinard-Watkins R, Hawley JR, Schafer C, Yau HL, Khuchua Z, Aman A, Al-Awar R, Gross A, Claypool SM, Bazinet RP, Lupien M, Chan S, De Carvalho DD, Minden MD, Bader GD, Stark KD, LeBlanc P, Schimmer AD. The Mitochondrial Transacylase, Tafazzin, Regulates AML Stemness by Modulating Intracellular Levels of Phospholipids. Cell Stem Cell. April, 2019. 24(4):621-636.e16.

Putman DM, Cooper TT, Sherman SE , Seneviratne AK, Hewitt M, Bell GI, Hess DA. Expansion of Umbilical Cord Blood Aldehyde Dehydrogenase Expressing Cells Generates Myeloid Progenitor Cells that Stimulate Limb Revascularization. Stem Cells. July, 2017. 6(7):1607-1619.

Seneviratne AK, Bell GI, Sherman S, Cooper T, Putman DM, Hess DA. “Expanded Hematopoietic progenitor cells reselected for high aldehyde dehydrogenase activity demonstrates islet regenerative functions. Stem Cells. 2016 Apr. 34(4): 873-887.  

Patel P, Brooks C, Seneviratne A, Hess DA and Séguin CA. Investigating microenvironmental regulation of human chordoma cell behaviour. PLOS ONE. 2014 Dec. 9(12):e115909.

Bell GI, Seneviratne AK, Nasri GN, Hess DA. Transplantation models to characterize the mechanism of stem cell induced islet regeneration. Current Protocols in Stem Cell Biology. 2013 Sep. 26:B:2B.4:2B.4.1–2B.4.35.

Sukhai MA, Prabha S, Hurren R, Rutledge AC, Lee AY, Sriskanthadevan S, Sun H, Wang X, Skrtic M, Seneviratne A, Cusimano M, Jhas B, Gronda M, Maclean N, Cho EE, Spagnuolo PA, Sharmeen S, Gebbia M, Urbanus M, Eppert K, Dissanayake D, Jonet A, Dassonville-Klimpt A, Li X, Datti A, Ohashi PS, Wrana J, Rogers I, Sonnet P, Ellis WY, Corey SJ, Eaves C, Minden MD, Wang JC, Dick JE, Nislow C, Giaever G, Schimmer AD. The Journal of Clinical Investigation. Lyososomal disruption as a therapeutic strategy for acute myeloid leukemia. 2013 Jan. 123: 315-328.  

Shi, Runjie Bill, Souzan Mirza, Diego Martinez, Catriona Douglas, John Cho, Jonathan C. Irish, David A. Jaffray, and Robert A. Weersink. "Cost-function testing methodology for image-based registration of endoscopy to CT images in the head and neck." Physics in Medicine & Biology (2020). https://doi.org/10.1088/1361-6560/aba8b3

Shi, Runjie Bill, Saha R, Li Y, Wong W, Buys Y, Trope G, Eizenman M. Novel Home Monitoring of Visual Fields with the Toronto Portable Perimeter. Investigative Ophthalmology & Visual Science. 2021 Jun 21;62(8):3483-.

Ahmed Y, Pereira A, Bowden S, Shi RB, Li Y, Ahmed II, Arshinoff SA. Multicenter Comparison of the Toronto Portable Perimeter with the Humphrey Field Analyzer: A Pilot Study. Ophthalmology Glaucoma. 2022 Mar 1;5(2):146-59.

Arshinoff SA, Shi RB. Relative efficacy of intracameral moxifloxacin injection methods. Journal of Cataract & Refractive Surgery. 2023 May 1;49(5):538-42.

Li-Han LY, Eizenman M, Shi RB, Buys YM, Trope GE, Wong W. Using Fused Data from Perimetry and Optical Coherence Tomography to Improve the Detection of Visual Field Progression in Glaucoma. Bioengineering. 2024 Mar 3;11(3):250.

Effat A, Bernards N, Shi RB, Zheng G, Wilson BC, Yasufuku K, Weersink RA. Investigating the effects of a temperature dependent photodynamic dose: A numerical study. Photodiagnosis and Photodynamic Therapy. 2024 Feb 1;45:103949.

Sindhwani, S., Chan, W. C. W. (2021) Nanotechnology for Modern Medicine: Next Steps Towards Clinical Translation. Journal of Internal Medicine (Early release available, In Galley Round)

Overchuk, M., Harmatys, K. M., Sindhwani, S., Rajora, M. A., Koebel, A., Charron, D. M., Syed, A. M., Chen, J., Pomper, M. G., Wilson, B. C., Chan, W. C. W., Zheng, G. (2021) Subtherapeutic Photodynamic Priming Facilitates Tumor Nanomedicine Delivery and Overcomes Desmoplasia. Nano Letters (21): 344–352

Sindhwani, S.*, Syed, A. M.*, Ngai, J., Kingston, B.R., Maiorino, M., Rothschild, J., MacMillan, P., Zhang, Y., Rajesh, N. U., Hoang T.,Wilhelm, S., Zilman, A., Gadde, S., Sulaiman, A., Ouyang B., Lin, Z., Wang, L., Egeblad, M., Chan, W. C. W. (2020) The entry of nanoparticles into solid tumours. Nature Materials (19): 566–575 (Selected for Journal Cover)

Syed, A. M.*, MacMillan, P. *, Ngai, J. *, Wilhelm, S., Sindhwani, S., Kingston, B.R., Wu, J. L. Y, Lin, Z. P., Ouyang, B., Kahiel, Z., Gadde, S., Chan, W. C. W. (2020) Liposome Imaging in Optically Cleared Tissues. Nano Letters 20(2):1362-1369

Kingston, B.R., Syed, A. M., Ngai, J., Sindhwani, S., Chan, W. C. W. (2019) Assessing micrometastases as a target for nanoparticles using 3D microscopy and machine learning. Proceedings of the National Academy of Sciences 116 (30):14937-14946

Malekjahani A., Sindhwani, S.*, Syed, A. M.*, Chan, W. C. W. (2019) Engineering Steps for Mobile Point-of-Care Diagnostic Devices. Accounts of Chemical Research 52 (9): 2406-2414

Lazarovits J.*, Sindhwani S.*, Tavares, A. J.*, Zhang, Y-W., Song F., Audet J., Krieger J. and Chan W. C. W. (2019) Supervised learning and mass spectrometry predicts the in vivo fate of nanomaterials. ACS Nano 13 (7):8023-8034

Dai Q., Wilhelm S., Ding D., Muhammad Syed A. M., Sindhwani S., Zhang Y-W., Chen Y. Y., MacMillan P., Chan W. C.W. (2018) Quantifying the in vivo targeting of ligand-coated nanoparticles to cancer cells. ACS Nano 12 (8): 8423–8435.

Syed A. M., Sindhwani S., Chan W. C. W. Making vessels more permeable. Nature Biomedical Engineering 1 (8), 629 (2017).

Syed, A. M.*, Sindhwani, S.*, Wilhelm, S., Kingston, B., Lee, D., Gommerman, J., Chan, W. C. W. Ultrasensitive Scattering Agents for Labeling Transparent Whole Organs. Journal of the American Chemical Society 139 (29) (2017).

Sindhwani, S.*, Syed, A. M.*, Wilhelm, S., Glancy, D. R., Chen, Y. Y., Dobosz M., Chan, W. C. W. Exploring Passive Clearing for 3D Optical Imaging of Nanoparticles in Intact Tissues Bioconjugate Chemistry  28 (1), 253-259 (2017).

Chen, Y.Y., Silva, P.N., Syed, A.M., Sindhwani, S., Rocheleau, J.V., Chan, W.C.W.. Clarifying intact 3D tissues on a microfluidic chip for high-throughput structural analysis. Proceedings of the National Academy of Sciences 113 (52), 14915-14920 (2016).

Sindhwani, S.*, Syed, A. M.*, Wilhelm, S., Glancy, D. R., Chen, Y. Y., Dobosz, M., & Chan, W. C. W. (2016). Three-Dimensional Optical Mapping of Nanoparticle Distribution in Intact Tissues. ACS Nano. 10(5), 5468–5478 (2016).

Tsang, B., Pritišanac, I., Scherer, S.W., Moses, A.M., Forman-Kay, J.D. Phase separation as a missing mechanism for interpretation of disease mutations. Cell. 2020. 183(7) 1742-1756. https://doi.org/10.1016/j.cell.2020.11.050.

Tsang, B.*, Kim, T.H.*, Vernon, R.M., Sonenberg, N., Kay L.E., Forman-Kay. J.D, Phospho-Dependent Phase Separation of FMRP and Caprin-1 Recapitulates Regulation of Translation and Deadenylation. Science. 2019. 365(6455) 825-829. [*Both authors contributed equally.] https://doi.org/10.1126/science.aax4240.

Tsang, B., Arsenault, J., Vernon, R.M., Lin, H., Sonenberg, N., Wang, LY., Bah, Alaji., and Forman-Kay, J.D. Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation. PNAS. 2019. 116(10) 4218-4227. https://doi.org/10.1073/pnas.1814385116.

Yu, Y., Zhang, Z., Walpole, G.F.W., Yu, Y., (2022) Kinetics of phagosome maturation is coupled to their intracellular motility. Commun Biol. 5(1):1014. doi: 10.1038/s42003-022-03988-4.

Montaño-Rendón, F., Walpole, G.F.W., Krause, M., Grinstein, S., and Fairn, G.D. (2022) PtdIns(3,4)P2, Lamellipodin, and VASP coordinate actin dynamics during phagocytosis in macrophages. J. Cell Bio. 221(11): e202207042. doi: 10.1083/jcb.202207042.

Walpole, G.F.W. Pacheco, J. Chauhan, N., Clark, J., Anderson, K.E., Abbas, Y.M., Brabant-Kirwan, D., Montaño-Rendón, F., Liu, Z., Zhu, H., Brumell, J.H., Deiters, A., Stephens, L.R., Hawkins, P.T., Hammond, G.R.V., Grinstein, S., and Fairn, G.D. (2022) Kinase-independent synthesis of 3-phosphorylated phosphoinositides by a phosphotransferase. Nat Cell Biol. 24(5):708-722. doi: 10.1038/s41556-022-00895-y.

Montaño-Rendón, F., Grinstein, S. & Walpole, G. F. W. (2021). Monitoring Phosphoinositide Fluxes and Effectors During Leukocyte Chemotaxis and Phagocytosis. Front. cell Dev. Biol. 9, 626136. doi: 10.3389/fcell.2021.626136.

Eisenberg, S., Haimov, E., Walpole, G. F. W., Plumb, J., Kozlov, M.M., Grinstein, S. (2020). Mapping the electrostatic profile of cellular membranes. Mol Biol Cell. mbcE19080436. doi: 10.1091/mbc.E19-08-0436.

Yang, M., Walpole, G. F. W., and Westman, J. (2020). Maintaining phagosome integrity during fungal infection: do or die? Microb. cell (Graz, Austria) 7, 323–325. doi:10.15698/mic2020.12.738.

Westman, J., Walpole, G. F. W., Kasper, L., Xue, B. Y., Elshafee, O., Hube, B., et al. (2020). Lysosome Fusion Maintains Phagosome Integrity during Fungal Infection. Cell Host Microbe, 1–15. doi:10.1016/j.chom.2020.09.004.

Walpole, G. F. W., Plumb, J. D., Chung, D., Tang, B., Boulay, B., Osborne, D. G., et al. (2020). Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation. Cell Rep. 31, 107721. doi:10.1016/j.celrep.2020.107721.

Walpole, G. F. W., and Grinstein, S. (2020). Endocytosis and the internalization of pathogenic organisms: focus on phosphoinositides. F1000Research 9, 368. doi:10.12688/f1000research.22393.1.

Walpole, G. F. W., Grinstein, S., and Westman, J. (2018) The role of lipids in host-pathogen interactions. IUBMB Life. 70, 384–392. doi: 10.1002/iub.1737

Wan H, Brathwaite S, Ai J, Hynynen K, Macdonald RL. Role of perivascular and meningeal macrophages in outcome following experimental subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2021 Jan 14:271678X20980296. doi: 10.1177/0271678X20980296. Epub ahead of print. PMID: 33444089.

Wennberg E, Abualsaud AO, Eisenberg MJ. Patient Management Following Percutaneous Coronary Intervention. JACC Adv. 2024 Dec 18;4(1):101453. doi: 10.1016/j.jacadv.2024.101453.

Romero P, Burger A, Wennberg E, Schmitteckert S, Holland-Cunz S, Schwab C, Günther P. Clinical Relevance of Pathological Diagnosis of Hirschsprung’s Disease with Acetylcholine-Esterase Histochemistry or Calretinin Immunohistochemistry. Children. 2024 Apr 3;11(4):428. doi: 10.3390/children11040428.

Peri K, Honeycutt L, Wennberg E, Windle SB, Filion KB, Gore G, Kudrina I, Paraskevopoulos E, Moiz A, Martel MO, Eisenberg MJ. Efficacy of interventions targeted at physician prescribers of opioids for chronic non-cancer pain: an overview of systematic reviews. BMC Med. 2024 Feb 20;22(1):76. doi: 10.1186/s12916-024-03287-1.

Mylocopos G, Wennberg E, Reiter A, Hébert-Losier A, Filion KB, Windle SB, Gore G, O'Loughlin JL, Grad R, Eisenberg MJ. Interventions for Preventing E-Cigarette Use Among Children and Youth: A Systematic Review. Am J Prev Med. 2024 Feb;66(2):351-370. doi: 10.1016/j.amepre.2023.09.028. Epub 2023 Oct 5.

Mathews JJ, Chow R, Wennberg E, Lau J, Hannon B, Zimmermann C. Telehealth palliative care interventions for patients with advanced cancer: a scoping review. Support Care Cancer. 2023 Jul 8;31(8):451. doi: 10.1007/s00520-023-07907-z.

Wennberg E, Windle SB, Filion KB, Thombs BD, Gore G, Benedetti A, Grad R, Ells C, Eisenberg MJ. Roadside screening tests for cannabis use: A systematic review. Heliyon. 2023 Mar 22:e14630. doi: 10.1016/j.heliyon.2023.e14630.

Lang F, Gerhäuser AS, Wild C, Wennberg E, Schmidt MW, Wagner M, Müller-Stich BP, Nickel F. Video-based learning of coping strategies for common errors improves laparoscopy training-a randomized study. Surg Endosc. 2023 Mar 21. doi: 10.1007/s00464-023-09969-w. Epub ahead of print.

Karadza E, Haney CM, Limen EF, Müller PC, Kowalewski KF, Sandini M, Wennberg E, Schmidt MW, Felinska EA, Lang F, Salg G, Kenngott HG, Rangelova E, Mieog S, Vissers F, Korrel M, Zwart M, Sauvanet A, Loos M, Mehrabi A, de Santibanes M, Shrikhande SV, Abu Hilal M, Besselink MG, Müller-Stich BP, Hackert T, Nickel F. Development of biotissue training models for anastomotic suturing in pancreatic surgery. HPB (Oxford). 2023 Feb 9:S1365-182X(23)00041-2. doi: 10.1016/j.hpb.2023.02.002. Epub ahead of print.

Lang F, Willuth E, Haney CM, Felinska EA, Wennberg E, Kowalewski KF, Schmidt MW, Wagner M, Müller-Stich BP, Nickel F. Serious gaming and virtual reality in the multimodal training of laparoscopic inguinal hernia repair: a randomized crossover study. Surg Endosc. 2023 Mar;37(3):2050-2061. doi: 10.1007/s00464-022-09733-6. Epub 2022 Oct 26.

Honeycutt L, Huerne K, Miller A, Wennberg E, Filion KB, Grad R, Gershon AS, Ells C, Gore G, Benedetti A, Thombs B, Eisenberg MJ. A systematic review of the effects of e-cigarette use on lung function. NPJ Prim Care Respir Med. 2022 Oct 22;32(1):45. doi: 10.1038/s41533-022-00311-w.

Romero P, Gerhaeuser A, Carstensen L, Kössler-Ebs J, Wennberg E, Schmidt MW, Mueller B, Günther P, Nickel F. Learning of intracorporal knot tying in minimally invasive surgery by video or expert instruction. Eur J Pediatr Surg. 2022 Oct 14. doi: 10.1055/a-1868-6050. Epub 2022 Jun 03.

Wennberg E, Windle SB, Filion KB, Gore G, Thombs BD, Kudrina I, Paraskevopoulos E, Martel MO, Kimmelman J, Johnson S, Taylor A, Eisenberg MJ. Interventions for physician prescribers of opioids for chronic non-cancer pain: protocol for an overview of systematic reviews. BMJ Open. 2022 Mar 31;12(3):e060964. doi: 10.1136/bmjopen-2022-060964.

Romero P, Carstensen L, Kössler-Ebs J, Wennberg E, Müller-Stich BP, Nickel F, Günther P. Learning and application of intracorporal slipping knot techniques in minimally invasive surgery. Surg Pract. 2021; 1 – 5. doi:10.1111/1744-1633.12534. Epub 2021 Oct 23.

Wennberg E, Lasry A, Windle SB, Filion KB, Thombs BD, Gore G, Fischer B, Eisenberg MJ. Non-medical cannabis use among Indigenous Canadians: A systematic review of prevalence and associated factors. Int J Drug Policy. 2021 Apr;90:103081. doi: 10.1016/j.drugpo.2020.103081. Epub 2020 Dec 24.

Wennberg EAB, Takata JL, Urbach DR. Elective surgery wait time reduction in Canada: A synthesis of provincial initiatives. Healthc Manage Forum. 2020 May;33(3):111-119. doi: 10.1177/0840470419900646. Epub 2020 Feb 5. 

Schmidt MW, Kowalewski KF, Schmidt ML, Wennberg E, Garrow CR, Paik S, Benner L, Schijven MP, Müller-Stich BP, Nickel F. The Heidelberg VR Score: development and validation of a composite score for laparoscopic virtual reality training. Surg Endosc. 2019 Jul;33(7):2093-2103. doi: 10.1007/s00464-018-6480-x. Epub 2018 Oct 16.

Kowalewski KF, Schmidt MW, Proctor T, Pohl M, Wennberg E, Karadza E, Romero P, Kenngott HG, Müller-Stich BP, Nickel F. Skills in minimally invasive and open surgery show limited transferability to robotic surgery: results from a prospective study. Surg Endosc. 2018 Apr;32(4):1656-1667. doi: 10.1007/s00464-018-6109-0. Epub 2018 Feb 12.

An E, Wennberg E, Nissim R, Lo C, Hales S, Rodin G. Death talk and relief of death-related distress in patients with advanced cancer. BMJ Support Palliat Care. 2020 Jun;10(2):e19. doi: 10.1136/bmjspcare-2016-001277. Epub 2017 Aug 2.

Regef J, Talisa L, Wiercigroch J, Lin RJ, Kahrs LA. Laryngeal surface reconstructions from monocular endoscopic videos: a structure from motion pipeline for periodic deformations. Int J Computer Assisted Radiology and Surgery (CARS). 2024 April. doi: 10.1007/s11548-024-03118-x.

Wiercigroch J, Ungi T, Idriss AM, Tfeil Y, Kikinis R, Mousavi P, Fichtinger G. Ultrasound-guided needle placement system optimized for translation to Mauritania. Proc. International Society for Optics and Photonics (SPIE) 11598, Medical Imaging 2021: Image-Guided Procedures, Robotic Interventions, and Modeling; 115980X (2021); doi: 10.1117/12.2582012.

Wiercigroch J, Hashtrudi-Zaad K, Ungi T, Bisleri G, Fichtinger G. Force and torque feedback in endoscopic vessel harvesting. Proc. SPIE 11315, Medical Imaging 2020: Image-Guided Procedures, Robotic Interventions, and Modeling; 113152Q (2020); doi: 10.1117/12.2550160

Asselin M, Wiercigroch J, Sunderland K, Kaufmann M, Janssen N, Ungi T, Lasso A, Rudan J, Fichtinger G. Accounting for surgical aerosol propagation delay in navigated intra-operative tissue characterization by mass spectrometry. Int J CARS (2019) 14 (Suppl 1): S45–S46; doi: 10.1007/s11548-019-01969-3

Asselin M, Kaufmann M, Wiercigroch J, Ungi T, Lasso A, Rudan J, Fichtinger G. Navigated real-time molecular analysis in the operating theatre, demonstration of concept. Proc. SPIE 10951, Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling; 109512C (2019); doi: 10.1117/12.2512586

Wiercigroch J, Baum Z, Ungi T, Fritz J, Fichtinger G. Validation of a low cost, adjustable, handheld needle guide for spine interventions. Proc. SPIE 10951, Medical Imaging 2019: Image Guided Procedures, Robotic Interventions, and Modeling; 109510L (2019). doi: 10.1117/12.2512562

Cottrell J, Zahr SK, Propst EJ, Narang I, Amin R, Chiang J, Al-Saleh S, Wolter NE. Morbidity and mortality from adenotonsillectomy in children with trisomy 21. Int J Pediatr Otorhinolaryngol. 2020 Nov;138:110377. doi: 10.1016/j.ijporl.2020.110377. Epub 2020 Sep 10. PMID: 33152968.

Zahr SK, Yang G, Kazan H, Borrett M, Yuzwa S, Voronova A, Kaplan D, Miller F. (2018). A translational repression complex in developing mammalian neural stem cells that regulates neuronal specification. Neuron. 97, 520-537.

Voronova A, Yuzwa S, Wang B, Zahr SK, Syal C, Wang J, Kaplan DR, Miller FD. (2017). Migrating interneurons secrete fractalkine to promote oligodendrocyte formation in the developing mammalian brain. Neuron. 94, 500-516.

Yang G, Cancino I, Zahr SK, Guskjolen A, Voronova A, Gallagher D, Frankland P, Miller F, Kaplan D. (2016). A Glo1-methylglyoxal pathway that is perturbed in maternal diabetes regulates embryonic and adult neural stem cell pools in offspring. Cell Reports. 17, 1022-1036.

Yuzwa S, Yang G, Borrett M, Clarke G, Cancino I, Zahr SK, Zandstra P, Kaplan D, Miller F. (2016). Proneurogenic ligands defined by modeling developing cortex growth factor communication networks. Neuron. 91, 988-1004.

Zeng AGX*, Nagree MS*, Jakobsen NA*, Shah S, Murison A, Cheong JG, Turkalj S, Lim INX, Jin L, Araujo J, Aguilar-Navarro AG, Parris D, McLeod J, Kim H, Lee HS, Zhang L, Boulanger M, Wagenblast E, Flores-Figueroa E, Wang B, Schwartz GW, Shultz LD, Josefowicz SZ, Vyas P, Dick JE, Xie SZ. Identification of a human hematopoietic stem cell subset that retains memory of inflammatory stress. bioRxiv (2023).

Zeng AGX, Iacobucci I, Shah S, Mitchell A, Wong G, Bansal S, Gao Q, Kim H, Kennedy JA, Arruda A, Minden MD, Haferlach T, Mullighan CG, Dick JE. Precise single-cell transcriptomic mapping of normal and leukemic cell states reveals unconventional lineage priming in acute myeloid leukemia. bioRxiv (2023).

Iacobucci I*, Zeng AGX*, Gao Q*, Garcia-Prat L*, Baviskar P, Shah S, Murison A, Voisin V, Chan-Seng-Yue M, Cheng C, Qu C, Bailey C, Lear M, Witkowski MT, Zhou X, Zaldivar Peraza A, Gangwani K, Advani AS, Luger SM, Litzow MK, Rowe JM, Paietta EM, Stock W, Dick JE, Mullighan CG. Single cell dissection of developmental origins and transcriptional heterogeneity in B-cell acute lymphoblastic leukemia. bioRxiv (2023).

Jakobsen NA*, Turkalj S*, Zeng AGX*, Stoilova B, Metzner M, Nagree MS, Shah S, Moore R, Usukhbayar B, Salazar MA, Gafencu GA, Kennedy A, Newman S, Kendrick BJL, Taylor AH, Afinowi-Luitz R, Gundle R, Watkins B, Wheway K, Beazley D, Murison A, Aguilar-Navarro AG, Flores-Figueroa E, Dakin SG, Carr AJ, Nerlov C, Dick JE, Xie SZ, Vyas P. Selective advantage of mutant stem cells in clonal hematopoiesis occurs by attenuating the deleterious effects of inflammation and aging. Cell Stem Cell (2024).

Ma S, Zeng AGX, Haibe-Kains B, Goldenberg A, Dick JE, Wang B. Integrate Any Omics: Towards genome-wide data integration for patient stratification. arXiv (2024).

Kim JC, Chan-Seng-Yue M, Ge S, Zeng AGX, Ng K, Gan OI, Garcia-Prat L, Flores-Figueroa E, Woo T, Zhang AXW, Arruda A, Chithambaram S, Dobson SM, Khoo A, Khan S, Ibrahimova N, George A, Tierens A, Hitzler J, Kislinger T, Dick JE, McPherson JD, Minden MD, Notta F. Transcriptomic classes of BCR-ABL1 lymphoblastic leukemia. Nature Genetics (2023)

Kan WL*, Dhagat U*, Kaufmann KB*, Hercus TR*, Nero TL#, Zeng AGX#, Toubia J#, Barry EF, Broughton SE, Gomez GA, Benard BA, Dottore M, Cheun Tung Shing KS, Boutzen H, Samaraweera SE, Simpson KJ, Jin L, Goodall GJ, Begley CG, Thomas D, Ekert PG, Tvorogov D, D’Andrea RJ, Dick JE, Parker MW, Lopez AF. Distinct assemblies of heterodimeric cytokine receptors govern stemness programs in leukemia. Cancer Discovery (2023)

Boila LD, Ghosh S, Bandyopadhyay SK, Jin L, Murison A, Zeng AGX, Shaikh W, Bhowmik S, Muddineni SSNA, Biswas M, Sinha S, Chatterjee SS, Mbong N, Gan OI, Bose A, Chakraborty S, Arruda A, Kennedy JA, Mitchell A, Lechmen ER, Banerjee D, Milyavsky M, Minden MD, Dick JE, Sengupta A. Leukemia (2023).

O’Brien C, Ling T, Berman J, Culp-Hill R, Reisz JA, Rondeau V, Jahangiri S, St-Germain J, Macwan V, Astori A, Zeng AGX, Hong JY, Li M, Yang M, Jana S, Dick JE, Lin H, Melnick A, Tikhonova AN, Arruda A, Minden MD, Raught B, D’Alessandro A, Jones CL. Simultaneous Inhibition of SIRT3 and Cholesterol Homeostasis Targets AML Stem Cells By Perturbing Fatty Acid β-Oxidation and Inducing Lipotoxicity. Haematologica (2023).

Che JLC, Bode D, Kucinski I, Cull AH, Bain F, Becker HJ, Jassinskaja M, Barile M, Boyd G, Belmonte M, Zeng AGX, Igarashi KJ, Rubio-Lara J, Shepherd MS, Clay A, Dick JE, Wilkinson AC, Nakauchi H, Yamazaki S, Gottgens B, Kent DG. Identification and characterization of in vitro expanded hematopoietic stem cells. (2022). EMBO Reports. 23, e55502

Zeng AGX, Bansal S, Jin L, Mitchell A, Chen WC, Abbas HA, Chan-Seng-Yue M, Voisin V, van Galen P, Tierens A, Cheok M, Preudhomme C, Dombret H, Daver N, Futreal PA, Minden MD, Kennedy JA, Wang JCY, Dick JE. A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia. (2022). Nature Medicine. 28, 1212-1223.

Krivdova G, Voisin V, Schoof EM, Marhon SA, Murison A, McLeod JL, Gabra MM, Zeng AGX, Aigner S, Yee BA, Shishkin AA, Van Nostrand EL, Hermans KG, Trotman-Grant AC, Mbong N, Kennedy JA, Gan OI, Wagenblast E, De Carvalho DD, Salmena L, Minden MD, Bader GD, Yeo GW, Dick JE, Lechman ER. Identification of the Global miR-130a Targetome Reveals a Role for TBL1XR1 in Hematopoietic Stem Cell Self-Renewal and t(8;21) AML. (2022). Cell Reports. 38, 110481.

Kaufmann KB, Zeng AGX, Coyaud E, Garcia-Prat L, Papalexi E, Murison A, Laurent E, Chan-Seng-Yue M, Gan OI, Pan K, McLeod J, Boutzen H, Zandi S, Takayanagi SI, Satija R, Raught B, Xie SZ, Dick JE. A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness. (2021). Nature Immunology. 22, 723-734.

Montefiori LE, Bendig S, Gu Z, Chen X, Polonen P, Ma X, Murison A, Zeng AGX, Garcia-Prat L, Dickerson K, Iacobucci I, Abdelhamed S, Hiltenbrand R, Mead PE, Mehr CM, Xu B, Cheng Z, Chang TC, Westover T, Ma J, Stengel A, Kimura S, Qu C, Valentine MB, Rashkovan M, Luger S, Litzow MR, Rowe JM, Den Boer ML, Wang V, Yin J, Kornblau SM, Hunger SP, Loh ML, Pui CH, Yang W, Crews KR, Roberts KG, Yang JJ, Relling MV, Evans WE, Stock W, Paietta EM, Ferrando AA, Zhang J, Kern W, Haferlack T, Wu G, Dick JE, Klco JM, Haferlach C, Mullighan CG. Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia. (2021). Cancer Discovery. 11, 2846-2867.

Garcia-Prat L, Kaufmann KB, Schneiter F, Voisin V, Murison A, Chen J, Chan-Seng-Yue M, Gan OI, McLeod J, Smith SA, Shoong MC, Parris D, Pan K, Zeng AGX, Krivdova G, Gupta K, Takayanagi SI, Wagenblast E, Wang W, Lupien M, Schroeder T, Xie SZ, Dick JE. TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate. (2021). Cell Stem Cell. 28, 1838-1850.

Xie SZ, Kaufmann KB, Wang W, Chan-Seng-Yue M, Gan OI, Laurenti E, Garcia-Prat L, Takayanagi SI, Ng SWK, Xu CJ, Zeng AGX, Jin L, McLeod J, Wagenblast E, Mitchell A, Kennedy JA, Liu Q, Boutzen H, Kleinau M, Jargstorf J, Holmes G, Zhang Y, Voisin V, Bader GD, Wang JCY, Hannun YA, Luberto C, Schroeder T, Minden MD, Dick JE. Sphingosine-1-phosphate signaling depletes leukemia stem cells by inducing differentiation. (2021). Blood Cancer Discovery. 2, 32.

Abelson S, Zeng AGX, Nofech-Mozes I, Wang TT, Ng SWK, Minden MD, Pugh TJ, Awadalla P, Shlush LI, Murphy T, Chan SM, Dick JE, Bratman SV. Integration of intra-sample contextual error modeling for improved detection of somatic mutations from deep sequencing. (2020). Science Advances. 6, eabe3722.

Zeng AGX, Brenna TA, Ndoja S. Fundamental trends within falling match rates: insights from the past decade of Canadian residency matching data. (2020). Canadian Medical Education Journal. 11, e31.

Xie SZ, Garcia-Prat L, Voisin V, Ferrari R, Gan OI, Wagenblast E, Kaufmann KB, Zeng AGX, Takayanagi SI, Patel I, Lee EK, Jargstorf J, Holmes G, Romm G, Pan K, Shoong M, Vedi A, Luberto C, Minden MD, Bader GD, Laurenti E, Dick JE. (2019). Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal. Cell Stem Cell. 25, 639-653.

Nguyen MM, Perlman G, Kim N, Wu CY, Daher V, Zhou A, Mathers EH, Anita NZ, Lanctôt KL, Herrmann N, Pakosh M, Swardfager W. Depression in type 2 diabetes: A systematic review and meta-analysis of blood inflammatory markers. Psychoneuroendocrinology. 2021 Oct 13;134:105448. doi: 10.1016/j.psyneuen.2021.105448. Epub ahead of print. PMID: 34687965.

Yang K, O’Cearbhaill ED, Liu SS, Zhou A, Chitnis GD, Hamilos AE, Xu J, Verma MKS, Giraldo JA,Kudo Y, Lee EA, Lee Y, Pop R, Langer R, Melton DA, Greiner DL, Karp JM, A therapeutic convection–enhanced macroencapsulation device for enhancing β cell viability and insulin secretion, Proc. Natl. Acad. Sci. Sep 2021, 118 (37) e2101258118; DOI: 10.1073/pnas.2101258118

Textbooks / Chapters

Seneviratne, AK. Mirali, S. Toronto Notes 2020: Comprehensive Medical Reference and Review for MCCQE I and USMLE II. Types and Graphics. 2020.

Binesh Marvasti, T. McQueen, S. Toronto Notes 2018: Comprehensive Medical Reference and Review for MCCQE I and USMLE II. Types and Graphics. 2018.

Schellhorn HE, Mohiuddin M, Hammond SM, Botts S. (2016). Regulators of Oxidative Stress Response Genes in Escherichia Coli and Their Conservation in Bacteria, in Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria (ed F. J. de Bruijn), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781119004813.ch60

Howell NA, Nasirzadeh Y. Population Health and Epidemiology. In: Toronto Notes 2017. Eds: Mukovozov I and Kim J. Toronto Notes (2017). PH1-PH26.

Voon V, Howell NA, Krack P. Psychiatric considerations in deep brain stimulation for Parkinson’s disease. In: Brain Stimulation: Handbook of Clinical Neurology. Eds. AM Lozano & M Hallett 2013. 116:147-54.

Jamal AJ, Morris AM. Antimicrobial Stewardship. In D Mertz, F Smaill, N Daneman (Eds.) Evidence-Based Infectious Diseases, 3rd Edition. Wiley-Blackwell 2018.

Ouyang B, Binesh Marvasti T, McQueen SM, Mukovozov I, Ali A, Rao R. (Eds.). (2018) Pharmacology You See: A High-Yield Pharmacology Review for Health Professionals. 2nd edition. Toronto, ON: Type & Graphics, Inc.

Rennie, M. Y., Mu, J., Rahman, A., Qu, D., Whiteley, K. J., Sled, J. G., & Adamson, S. L. (2014). The Uteroplacental, Fetoplacental, and Yolk Sac Circulations in the Mouse. In Croy, B. A., Yamada, A. T., DeMayo, F. J., & Adamson, S. L. (Eds.). (2014), The guide to investigation of mouse pregnancy (pp. 201-210). Academic Press.