Papers (alphabetical, by student’s last name)

Abraham KJ, Ostrowski L, and Mekhail K. (2016) Non-coding RNAs as targets and effectors of calorie restriction. Journal of Molecular Biology. pii: S0022-2836(16)30334-5


Abraham KJ*, Chan NY*, Salvi JS*, Ho Brandon, Hall A, Vidya R, Guo R, Killackey S, Liu N, Lee JE, Brown GW, and Mekhail K. (2016) Mg2+-driven R-loop resolution promoting genome integrity and responding to calorie restriction. Nucleic Acids Research. 44(18):8870-8884.

Abraham KJ, Zhang X, Vidal R, Pare G, Feilotter H, Tron VA. (2016) Roles for microRNA-375 in neuroendocrine differentiation and tumour suppressor via Notch pathway suppression in Merkel cell carcinoma. Am. J. Pathol. 186(4):1025-35.

Chung DKC, Chan JN, Strecker J, Zhang W, Ebrahimi-Ardebili S, Lu T, Abraham KJ, Durocher D, and Mekhail K (2015). Perinuclear tethers license telomeric DSBs for a broad kinesin- and NPC-dependent DNA repair process. Nature Communications. 6:7742.

Szafranski K*, Abraham KJ*, and Mekhail K. (2015) Non-coding RNA in neural function, disease, and aging. Front. Genet. 6(87):1-16.

Wang C, Armstrong SM, Sugiyama MG, Tabuchi A, Krauszman A, Kuebler WM, Mullen B, Advani S, Advani A, Lee WL. Influenza Primes Human Lung Microvascular Endothelium to Leak upon Exposure to Staphylococcus aureus.  Am J Respir Cell Mol Biol. 2015 Feb 18. [Epub ahead of print]

Armstrong SM, Wang C, Tigdi J, Si X, Dumpit C, et al. (2012) Influenza Infects Lung Microvascular Endothelium Leading to Microvascular Leak: Role of Apoptosis and Claudin-5. PLoS ONE 7(10): e47323. doi:10.1371/journal.pone.0047323

Armstrong SM, Khajoee V, Wang C, Wang T, Tigdi J, Yin J, Kuebler WM, Gillrie M, Davis SP, Ho M, Lee WL.  Co-regulation of transcellular and paracellular leak across microvascular endothelium by dynamin and Rac.  Am. J. Pathol. Vol. 180, No. 3, March 2012.

Carr MJ and Johnston APW. (2017). Schwann cells as drivers of tissue repair and appendage regeneration. Current Opinion in Neurobiology. Oct 2017. [Epub ahead of print]

Carr MJ, Li Y, Rezakhanlou AM, Ghahary A. (2017). Keratinocyte-releasable factors stimulate the expression of granulocyte colony-stimulating factor in human dermal fibroblasts. Journal of Cellular Biochemistry. 118(2):308-317.

Johnston APW, Yuzwa SA*, Carr MJ*, Mahmud N, Storer M, Krause MP, Jones K, Paul S, Kaplan DR, Miller FD. (2016). Dedifferentiated Schwann cell precursors secreting paracrine factors are required for regeneration of the mammalian digit tip. Cell Stem Cell. 19(4):433-448. [* denotes co-authors]

Chavez-Muñoz C, Hartwell R, Jalili RB, Carr M, Kilani RT, Jafarnejad SM, Rahmani-Neishabour E, Forouzandeh F, Boyce ST, Ghahary A. (2012). Application of an Indoleamine 2,3-Dioxygenase (IDO) expressing skin substitute improves scar formation in a fibrotic animal model. Journal of Investigative Dermatology. 132(5):1501-5.

Carr M, Chavez-Muñoz C, Lai A, Ghahary A. (2011). Dermal fibroblasts influence the expression profile of 14-3-3 proteins in human keratinocytes. Molecular and Cellular Biochemistry. 353(1-2):205-14.

Kilani RT, Medina A, Aitken A, Jalili RB, Carr M, Ghahary A. (2008). Identification of different isoforms of 14-3-3 protein family in human dermal and epidermal layers. Molecular and Cellular Biochemistry. 314(1-2):161-169.

Chrystoja CC, Darling GE, Diamant NE, Kortan PP, Tomlinson GA, Deitel W, Laporte A, Takata J, Urbach DR. Achalasia-Specific Quality of Life After Pneumatic Dilation or Laparoscopic Heller Myotomy With Partial Fundoplication: A Multicenter, Randomized Clinical Trial. Am J Gastroenterol. 2016;111:1536-1545.

Civitarese, R.A., Talior-Volodarsky, I., Desjardins, JF., Kabir, G., Switzer, J., Mitchell, M., Kapus, A., McCulloch C, A., Gullberg, D. and Connelly, K. A. (2016). The α11 integrin mediates fibroblast- extracellular matrix- cardiomyocyte interactions in health and disease. Am J Physiol Heart Circ Physiol. In Press

Tharmaratnam, T., Civitarese, R.A., Tabobondung, T., and Tabobondung, T.A. (2016). Exercise becomes Brain: Sustained Aerobic Exercise Enhances Hippocampal Neurogenesis. The Journal of Physiology. In Press.

Matkar P. N., Cao W. J., Chen H. H., Civitarese, R., Jog R., and Bugyei-Twum A. (2015). Rac1: an emerging player in stretch-stimulated glucose transport. The Journal of Physiology, 593(8), 1771-1772.

Deshwar, A.R., Chng, S.C., Ho, L., Reversade, B., Scott, I.C. (2016). The Apelin receptor enhances Nodal/TGFβ signaling to ensure proper cardiac development. Elife, 5: e13758.

Lou, X., Deshwar, A.R., Crump, J.G., and Scott, I.C. (2011). Smarcd3b and Gata5 promote a cardiac progenitor fate in the zebrafish embryo. Development. 138: 3113-3123.

Manoranjan, B., Dey, A., Wang, X., Kuzyk, A., Petticrew, K., Charruthers, C., & Arnold, I. (2017).

The role of nongovernment organizations in engaging medical students in research. Journal of

Investigative Medicine. Jim-2016-000348

Skinnider, M., Squair J., Twa, D., Ji, J., Kuzyk, A., Wang, X., Steadman, P. E., Zaslavsky K., Dey, A., Eisenberg, M., Gagne, E., HayGlass, K., Lewis, J., Margetts, P., Underhill, A., Rosenblum N., & Raymond, L. (2017). Canadian MD/PhD programs train leaders in clinical and translational research: Outcomes from a national survey of alumni. CMAJ Open

Dey, A.K., Stamenova, V., Turner, G., Black, S.E., & Levine, B. (2016). Pathoconnectomics of

cognitive impairment in cerebral small vessel disease: a systematic review. Alzheimer’s &

Dementia. doi: 10.1016/j.jalz.2016.01.007.

Dey, A.K., Alyass, A., Muir, R.T., Black, S.E., Swartz, R.H., Murray, B.J., & Boulos, M.I. (2015).

Validity of self-report of cardiovascular risk factors in a population at high risk for stroke. Journal

of Stroke and Cerebrovascular Diseases. 24(12), 2860-5. doi:


Dey, A. & Ravishankar, N. (2014). Rising Burden of Geriatric Mental Illness – need for more specialized training. Journal of Clinical Gerontology and Geriatrics, 5(4), 143-144.

Dey, A.K., (2014). Adding Life to Years: Physiatry, Neurorehabilitation, and knowledge translation. UTMJ, 92(1), 29-32.

Dey, A.K., (2014). Brain Stimulation and its Role in the Assessment and Management of Movement Disorders. UTMJ, 92(1), 15-17.

Dey, A.K, Stamenova, V., Bacopulos, A., Jeyakumar, N., Turner, G., Black, S.E., & Levine, B. (2014). Functional neuroimaging of cerebral small vessel disease, behaviour and neurorehabilitation following goal management training: pilot. Archives of Physical Medicine and Rehabilitation, 95(10), 51.

Francis, P., Eastwood, K.W., Bodani, V.P., Price, K., Upadhyaya, K., Podolsky, D., Azimian, H., Looi, T. and Drake, J.M. (2017). Miniaturized Continuum Instruments for the da Vinci Research Kit. IEEE Robotics and Automation Magazine, Accepted for Publication.

Eastwood, K.W., Bodani, V.P. and Drake, J.M. (2016). Three-Dimensional Simulation of Collision-Free Paths for Combined Endoscopic Third Ventriculostomy and Pineal Region Tumor Biopsy: Implications for the Design Specifications of Future Flexible Endoscopic Instruments. Operative Neurosurgery, 12(3), 231-238.

Eastwood, K.W., Azimian, H., Carrillo, B., Looi, T., Naguib, H. E. and Drake, J. M. (2016). Kinetostatic design of asymmetric notch joints for surgical robots. Proceedings of the 2016 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) (pp. 2381-2387). Daejeon: IEEE.

Eastwood, K.W., Looi, T., Naguib, H. E. and Drake, J.M. (2015). Design optimization of neuroendoscopic continuum instruments for third ventriculostomy and tumor biopsy. Proceedings of the 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (pp. 4853-4856). Milan: IEEE.

King, N.K.K., Krishna, V., Basha, D., Elias, G., Sammartino, F., Hodaie, M., Lozano, A.M., and Hutchison, W.D. (2016). Microelectrode recording findings within the tractography-defined ventral intermediate nucleus. J. Neurosurg. 1–7.

Murphy, K., Elias, G., Steppan, J., Boxley, C., Balagurunathan, K., Victor, X., Meaders, T., and Muto, M. (2016a). Percutaneous Treatment of Herniated Lumbar Discs with Ozone: Investigation of the Mechanisms of Action. J Vasc Interv Radiol 27, 1242–1250.e3.

Krishna, V., Sammartino, F., Yee, P., Mikulis, D., Walker, M., Elias, G., and Hodaie, M. (2016). Diffusion tensor imaging assessment of microstructural brainstem integrity in Chiari malformation Type I. J. Neurosurg. 1–8.

Murphy, K., Oaklander, A.L., Elias, G., Kathuria, S., and Long, D.M. (2016b). Treatment of 213 Patients with Symptomatic Tarlov Cysts by CT-Guided Percutaneous Injection of Fibrin Sealant. AJNR Am J Neuroradiol 37, 373–379.

Krishna, V., Elias, G., Sammartino, F., Basha, D., King, N.K.K., Fasano, A., Munhoz, R., Kalia, S.K., Hodaie, M., Venkatraghavan, L., et al. (2015). The effect of dexmedetomidine on the firing properties of STN neurons in Parkinson’s disease. Eur. J. Neurosci. 42, 2070–2077.

Chen, L., Elias, G., Yostos, M.P., Stimec, B., Fasel, J., and Murphy, K. (2015). Pathways of cerebrospinal fluid outflow: a deeper understanding of resorption. Neuroradiology 57, 139–147.

Murphy, K.J., Elias, G., Jaffer, H., and Mandani, R. (2013). A study of inventiveness among Society of Interventional Radiology members and the impact of their social networks. J Vasc Interv Radiol 24, 931–937.

Lipsman, N., Woodside, D.B., Giacobbe, P., Hamani, C., Carter, J.C., Norwood, S.J., Sutandar, K., Staab, R., Elias, G., Lyman, C.H., et al. (2013). Subcallosal cingulate deep brain stimulation for treatment-refractory anorexia nervosa: a phase 1 pilot trial. Lancet 381, 1361–1370.

Murphy, K.J., Elias, G., Jaffer, H., and Mandani, R. (2012). Where good ideas come from: where the wild things are! J Vasc Interv Radiol 23, 494–496.

McDonald, C.R., A.L. Conroy, M. Hawkes, R.E. Elphinstone, J.L. Gamble, K. Hayford, S. Namasopo, R.O. Opoka, W.C. Liles, and K.C. Kain. (2016) Brain-derived neurotrophic factor is associated with disease severity and clinical outcome in Ugandan children admitted to hospital with severe malaria. Pediatr Infect Dis J. doi: 10.1097/INF.0000000000001382

Elphinstone, R.E., A.L. Conroy, M. Hawkes, L. Hermann, S. Namasopo, H.S. Warren, C.C. John, W.C. Liles, and K.C. Kain. (2016). Alterations in systemic extracellular heme and hemopexin are associated with adverse clinical outcomes in Ugandan children with severe malaria. J Infect Dis 214 (8): 1268-75.

Conroy, A.L., M. Hawkes, R.E. Elphinstone, C. Morgan, L. Hermann, K.R. Barker, S. Namasopo, R.O. Opoka, C.C. John, W.C. Liles, and K.C. Kain. (2016). Acute kidney injury is common in pediatric severe malaria and is associated with increased mortality.  Open Forum Infectious Diseases 3(2): 1-9, doi: 10.1093/ofid/ofw046.

Elphinstone, R.E., F. Riley, T. Lin, S. Higgins, A. Dhabangi, C. Musoke, C. Cserti-Gazdewich, R.F. Regan, H. Shaw Warren, and K.C. Kain. (2015). Dysregulation of the haem-haemopexin axis is associated with severe malaria in a case-control study of Ugandan children.  Malaria Journal 14:511.

Higgins S.J., Elphinstone R.E., and Kain K.C. (2014). Adjunctive Therapies for Malaria. In Encyclopedia of Malaria. Edited by Hommel M, Kremsner PG: Springer New York; 1-18.

Elphinstone, R.E., S.J. Higgins, and K.C. Kain.  (2013). Prevention of Malaria in Travelers: Bite Avoidance and Chemoprophylactic Measures.  Current Treatment Options in Infectious Diseases. DOI 10.1007/s40506-013-0005-x.

Hawkes, M., R.E. Elphinstone, A.C. Conroy, and K.C. Kain. (2013). Contrasting pediatric and adult cerebral malaria: role of the endothelial barrier. Virulence 4(6):543-555.

McDonald*, C.R., R.E. Elphinstone*, and K.C. Kain. (2013). The impact of placental malaria on neurodevelopment of exposed infants: a role for the complement system? Trends in Parasitology 29(5):213-219. (*Joint first authors)

Fuller, J. What are chronic diseases? Synthese 2017; doi:10.1007/s11229-017-1368-1.

Loughlin, M., Fuller, J., Bluhm, R., Buetow, S. and K. Borgerson. Theory, experience and practice. Journal of Evaluation in Clinical Practice 2016;22:459-465.

Hamer, D., Kancir, J., Fuller, J., Kuper, A., Bryden, P. and A. Peterkin. A Narrative Companion for the Medical Curriculum. Keeping Reflection Fresh: Top Educators Share Their Innovations in Health Professional Education (Kent State Press, 2016).

Fuller, J. and L.J. Flores. Translating trial results in clinical practice: the Risk GP Model. Journal of Cardiovascular Translational Research 2016;9: 167-168.

Upshur, R.E. and J. Fuller. Randomized controlled trials in the West African Ebola virus outbreak. Clinical Trials 2016;13(1): 10-12.

Fuller, J. Making Medical Knowledge by M. Solomon. Medical Humanities (The Reading Room) 2016:

Fuller, J. and L.J. Flores. The Risk GP Model: the standard model of prediction in medicine. Studies in History and Philosophy of Biological and Biomedical Sciences 2015;54: 49-61.

Fuller, J., Broadbent, A. and L.J. Flores. Prediction in epidemiology and medicine. Studies in History and Philosophy of Biological and Biomedical Sciences 2015;54:45-48.

Loughlin, M., Bluhm, R., Fuller, J., Buetow, S., Borgerson, K., Lewis, B. and B. Kious. Diseases, patients and the epistemology of practice: mapping the borders of health, medicine and care. Journal of Evaluation in Clinical Practice 2015;21: 357-364.

Fuller, J. The art of medicine. Canadian Medical Association Journal 2015;187(14): 1078.

Fuller, J., Apramian, T. and C. Min. Social science and humanities research in MD-PhD training. Academic Medicine 2015;90(10): 1292.

Loughlin, M., Bluhm, R., Fuller, J., Buetow, S., Upshur, R.E.G., Borgerson, K., Goldenberg, M.J. and E. Kingma. Philosophy, medicine and health care – where we have come from and where we are going. Journal of Evaluation in Clinical Practice 2014;20(6): 902–907.

Fuller, J. Philosophy of Epidemiology by A. Broadbent. Journal of Evaluation in Clinical Practice 2014;20(6): 1002-1004.

Pitchers, K., Coppens, C., Beloate, L., Fuller, J., Van, S., Frohmader, K., LaViolette, S., Lehman, M. and L. Coolen. Endogenous opioid-induced neuroplasticity of dopaminergic neurons in the ventral tegmental area influences natural and opiate reward. Journal of Neuroscience 2014;34(26): 8825-8836.

Fuller, J., Flores, L.J., Upshur, R.E. and M.J. Goldenberg. Renaissance or reformation for evidence based medicine? British Medical Journal 2014;349: g4902.

Tracy, C. S., Fuller, J. and R.E.G. Upshur. Polypharmacy: prevention and management. Canadian Medical Association Journal 2014;186(17): 1321.

Fuller, J. and R.E.G. Upshur. Logos, ethos and pathos in balance –the care of the patient and the soul of the clinic: person-centered medicine as an emergent model of modern clinical practice. European Journal for Person Centered Healthcare 2014;2(1): 22-29.

Fuller J., Upshur R.E. and M. Goldenberg. Doctors must be trained to assess credibility. Canadian Medical Association Journal 2014;186(1): 64.

Fuller, J. Rhetoric and argumentation: how clinical practice guidelines think. Journal of Evaluation in Clinical Practice 2013;19: 433–441.

Fuller, J.  Rationality and the generalization of randomized controlled trial evidence. Journal of Evaluation in Clinical Practice 2013;19: 644-647.

Fuller, J., Sankar, A. and R.E.G. Upshur. Appendix 1: Concepts in Evidence-Informed Medical Practice. The Essentials of Clinical Examination Handbook 7th Edition (eds . J. Hall, K. Piggott, M. Vojvodic & K. Zaslavsky), 571-583 (Thieme, 2013).

Fuller, J. and M.M. Olszewski. Medical history in Canadian undergraduate medical education, 1939-2012. Canadian Bulletin of Medical History 2013;30(2): 199-209.

Fuller, J., Prescott, I.A., Moro, E., Toda, H., Lozano, A., and W.D. Hutchison. Pallidal deep brain stimulation for a case of hemidystonia secondary to a striatal stroke. Stereotactic and Functional Neurosurgery 2013;91(3): 190-197.

Fuller, J. and R.E.G. Upshur. Medication regimen complexity and the care of the chronically ill patient. International Journal of Person-Centered Medicine 2011;1(4): 719-725.

Fuller, J. Darwinian medicine: the past and present state of medicine’s unifying science. University of Toronto Medical Journal 2011;88(3): 209-214.

Howell NA, Nasirzadeh Y. Population Health and Epidemiology. In: Toronto Notes 2017. Eds: Mukovozov I and Kim J. Toronto Notes (In Press). PH1-PH26.

Howell NA, Prescott IA, Lozano AM, Hodaie M, Voon V, Hutchison WD.  Preliminary evidence for human globus pallidus pars interna neurons signaling reward and sensory stimuli.  Neuroscience. 2016; 328:30-9.

Howell NA, Maher J, Fasano A.  Acetazolamide-induced myokymia.  Parkinsonism Relat Disord. 2015; 21(5): 542-3.

Banca P, Lange I, Worbe Y, Howell NA, Irvine M, Harrison NA, Moutoussis M, Voon V. Addict Biol. Reflection impulsivity in binge drinking: behavioural and volumetric correlates. 2015;21:504-15.

Worbe Y, Irvine M, Lange I, Kundu P, Howell NA, Harrison NA, Bullmore ET, Robbins TW, Voon V. Biol Psych. Neuronal correlates of risk-seeking attitudes to anticipated losses in binge drinkers. 2014; 76(9):717-24.

Voon V, Rizos A, Chakravartty R, Mulholland N, Robinson S, Howell NA, Harrison N, Vivian G, Ray Chaudhuri K. Impulse control disorders in Parkinson’s disease: decreased striatal dopamine transporter levels.  J Neurol Neurosurg Psychiatry. 2014 Feb;85(2):148-52. doi:

Howell NA, Worbe Y, Lange I, Tait R, Irvine M, Banca P, Harrison NA, Bullmore ET, Hutchison WD, Voon V.  Increased ventral striatal volume in college-aged binge drinkers. PLOS One. 2013; 8(9): e74164.

Voon V, Howell NA, Krack P. Psychiatric considerations in deep brain stimulation for Parkinson’s disease. In: Brain Stimulation: Handbook of Clinical Neurology. Eds. AM Lozano & M Hallett 2013. 116:147-54.

Jamal AJ, Husain S, Li Y, Famure O, Kim SJ. Risk factors for late-onset cytomegalovirus infection or disease in kidney transplant recipients. Transplantation 2014; 97: 569-75.

Jamal AJ, Resende MR, Prochnow T, et al. Simkania negevensis and acute cellular rejection in lung transplant recipients. Clinical Transplantation 2015; 29(8): 705-11.

Ouyang B, Li LD, Mount J, Jamal AJ, Berry L, Simone C, Law M, Tai RM. Incidence and characteristics of needlestick injuries among medical trainees at a community teaching hospital: A cross-sectional study. J Occup Health 2017; 59(1): 63-73.

Lane NE, Maxwell CJ, Gruneir A, Bronskill, SE, Wodchis, WP. Absence of a socioeconomic gradient in older adults’ survival with multiple chronic conditions. EBioMedicine 2015; 2(12): 2094-2100.


Pitzul KB, Lane NE, Voruganti T, Khan AI, Innis J, Wodchis WP, Baker GR. The role of context in care transition interventions for older adults: A realist synthesis protocol. BMJ Open 2015; 5: e008686.

Adoue V, Schiavi A*, Light N*, Almlöf JC, Lundmark P, Ge B, Kwan T, Caron M, Rönnblom L, Wang C, Chen SH, Goodall AH, Cambien F, Deloukas P, Ouwehand WH, Syvänen AC, Pastinen T, Allelic expression mapping across cellular lineages to establish impact of non‐coding SNPs. Molecular Systems Biology 2014 Oct 17; 10 (10)

  Light N*, Adoue V*, Ge B, Chen C, Kwan T, Pastinen T, Interrogation of allelic chromatin states in human cells by high-density ChIP-genotyping. Epigenetics 2014 Sep 7; 9 (9), 1238-1251.

Guha D, Alotaibi NM, Nguyen N, Gupta S, McFaul C, Yang VX, (2017) Augmented Reality in Neurosurgery: A Review of Current Concepts and Emerging Applications. Canadian Journal of Neurological Sciences, 1-11.

McFaul CMJ, Fernandez-Gonzalez R, (2017) Shape of my heart: cell-cell adhesion and cytoskeletal dynamics during Drosophila cardiac morphogenesis. Experimental Cell Research.

Wang MFZ, Hunter MV, Wang G, McFaul C, Yip CM, Fernandez-Gonzalez R, (2017) Automated cell tracking identifies mechanically oriented cell divisions during Drosophila axis elongation. Development 144, no. 7: 1350-1361.

Leith JS, Kamanzi A, Sean D, Berard D, Guthrie AC, McFaul CMJ, Slater GW, de Haan HW, Leslie SR, (2016) Free Energy of a Polymer in Slit-like Confinement from the Odijk Regime to the Bulk. Macromolecules 49, no. 23: 9266-9271.

Arsenault A, Leith JS, Henkin G, McFaul CMJ, Tarling M,Talbot R, Berard D, Michaud F, Scott S, Leslie SR, (2015) Open-frame system for single-molecule microscopy. Review of Scientific Instruments 86, no. 3: 033701.

Berard DJ, Michaud F, Mahshid S, Jalal Ahamed M, McFaul CMJ, Leith JS, Bérubé P, Sladek R, Reisner W, Leslie SR, (2014) Convex lens-induced nanoscale templating. Proceedings of the National Academy of Sciences 111, no. 37 : 13295-13300.

Acai, A., McQueen, S.A., Fahim, C., Wagner, N., McKinnon, V., Boston, J., Maxwell, C., and Sonnadara, R.R. (In Press). It’s not the form; it’s the process: a phenomenological study on the use of creative professional development workshops to improve teamwork and communication skills. Medical Humanities.

Nousiainen, M., McQueen, S.A., Hall, J., Kraemer, W., Ferguson, P., Marsh, L., Reznick, R., Reed, M.R. & Sonnadara, R. (In Press). Resident education in orthopaedic trauma: The future role of competency based medical education. The Bone and Joint Journal. 

Acai, A., McQueen, S.A., McKinnon, V. & Sonnadara, R.R. (In Press). Using art for the development of teamwork and communication skills among healthcare professionals: A literature review. Arts & Health.

McQueen, S.A., Petrisor, B., Bhandari, M., Fahim, C., McKinnon, V., and Sonnadara, R.R. (2016). Examining the barriers to meaningful assessment and feedback in medical training. The American Journal of Surgery. 211(2), 464-475. 

Harikesh S. Wong, Valentin Jaumouillé, Spencer Freeman, Sasha Doodnauth, Daniel Schlam, Dr. Johnathan Canton, Ilya Mukovozov, Amra Saric, Sergio Grinstein, and Lisa A Robinson. (2016). Chemokine signalling enhances CD36 responsiveness towards oxidized low-density lipoproteins and accelerates foam cell formation. Cell Reports. 14(12):2859-71.


Ilya Mukovozov, YiWei Huang, Qiuwang Zhang, Guang Ying Liu, Allan Siu, Yaroslav Sokolskyy, Sajedabanu Patel, Sharon J Hyduk, Michael JB Kutryk, Myron I Cybulsky, and Lisa A Robinson. (2015). The neurorepellent, Slit2, inhibits post-adhesion stabilization of monocytes tethered to vascular endothelial cells. Journal of Immunology. 195(7): 3334-3344.

Ng, E., Browne, C. J., Samsom, J. N., & Wong, A. H. C. (2016). Depression and substance use comorbidity: what we have learned from animal studies. The American Journal of Drug and Alcohol Abuse, 2990(June), 1–19. doi:10.1080/00952990.2016.1183020

Ng, E., Varaschin, R. K., Su, P., Browne, C. J., Hermainski, J., Le Foll, B., … Wong, A. H. C. (2016). Neuronal calcium sensor-1 deletion in the mouse decreases motivation and dopamine release in the nucleus accumbens. Behavioural Brain Research, 301, 213–225. doi:10.1016/j.bbr.2015.12.037

McGirr, A., Lipina, T. V, Mun, H.-S., Georgiou, J., Al-Amri, A. H., Ng, E., … Roder, J. C. (2015). Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory Acquisition. Neuropsychopharmacology, 801(February 2016), 1–13. doi:10.1038/npp.2015.240

Mun, H.-S., Saab, B. J., Ng, E., McGirr, A., Lipina, T. V., Gondo, Y., … Roder, J. C. (2015). Self-directed exploration provides a Ncs1-dependent learning bonus. Scientific Reports, 5, 17697. doi:10.1038/srep17697

Le Foll, B., Ng, E., Di Ciano, P., & Trigo, J. M. (2015). Psychiatric disorders as vulnerability factors for nicotine addiction: What have we learned from animal models? In D. J. K. Balfour & M. R. Munafo (Eds.), Current topics in behavioral neurosciences (Vol. 24, pp. 155–170). Springer International Publishing. doi:10.1007/978-3-319-13482-6

Ng, E., Wang, X., Keow, J., & Yoon, Y. (2015). Fostering mentorship for clinician-investigator trainees: overview and recommendations. Clinical and Investigative Medicine, 38(1), E1–E10.

Ng, E., McGirr, A., Wong, A. H. C., & Roder, J. C. (2013). Using rodents to model schizophrenia and substance use comorbidity. Neuroscience and Biobehavioral Reviews, 37(5), 896–910. doi:10.1016/j.neubiorev.2013.03.025

Ouyang B, Li LD, Mount J, Jamal AJ, Berry L, Simone C, Law M, Tai RM. Incidence and Characteristics of Needlestick Injuries among Medical Trainees at a Community Teaching Hospital: A Cross-Sectional Study. Journal of Occupational Health. 2016 Nov 22:15-0253.

Jones AA, Ng E, Deguise MO, Mak L, Ouyang B, Sivapragasam M, MacNairn IA, Narth S, Benesch MG, Forrest L, Wang X. MD/PhD Training in Canada: Results from a national trainee and program director review. Clinical and investigative medicine. Médecine clinique et experimentale. 2016 Sep 11;39(4):E132.

Tsoi KM, MacParland SA, Ma XZ, Spetzler VN, Echeverri J, Ouyang B, Fadel SM, Sykes EA, Goldaracena N, Kaths JM, Conneely JB, Alman BA, Selzner M, Ostrowski MA, Adeyi OA, Zilman A, McGilvray ID, Chan WCW. (2016) Clearance of hard nanomaterials by the liver: a mechanistic study. Nature Materials 15, 1212–1221 (2016).

Ouyang B. The Resistance to Antisepsis in the 19th Century: A Briefing on Two European Antisepsis Proponents. (2015). University of Toronto Medical Journal; 92(3):92-94.

Pouget JG, Gonçalves VF, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Spain SL, Finucane HK, Raychaudhuri S, Kennedy JL and Knight J (2016) Genome-wide association studies suggest limited immune gene enrichment in schizophrenia compared to five autoimmune diseases. Schizophr Bull. doi: 10.1093/schbul/sbw059 [Epub ahead of print].

Han B*, Pouget JG*, Slowikowski K, Stahl E, Lee CH, Diogo D, Hu X, Park YR, Kim E, Gregersen PK, Dahlqvist SR, Worthington J, Martin J, Eyre S, Klareskog L, Huizinga T, Chen WM, Onengut-Gumuscu S, Rich SS, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray NR and Raychaudhuri S (2016) A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases. Nature Genetics. doi: 10.1038/ng.3572 [Epub ahead of print]. (*co-first authors)

Prins BP, […], Pouget JG, Jamshidi Y, Snieder H and Alizadeh BZ (2016) Investigating the causal relationship of C-reactive protein with 32 complex somatic and psychiatric outcomes: a large scale cross-consortia Mendelian randomization study. PLoS Medicine. doi: 10.1371/journal.pmed.1001976.

Ellinghaus D, Jostins L, Spain SL, Cortes A, Bethune J, Han B, Park YR, Raychaudhuri S, Pouget JG, […], Franke A (2016) Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. Nature Genetics. doi:10.1038/ng.3528 [Epub ahead of print].

Felsky D, De Jager PL, Schneider JA, Arfanakis K, Fleischman DA, Arvanitakis Z, Honer WG, Pouget JG, Mizrahi R, Pollock BG, Kennedy JL, Bennett DA and Voineskos AN (2016) Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant. J Cereb Blood Flow Metab. 36(4):819-30.

Kennedy JL, Xiong N, Yu J, Zai CC, Pouget JG, Li J, Liu K, Qing H, Wang T, Martin E, Levy DL and Lin Z (2016) Increased nigral SLC6A3 activity in schizophrenia patients: findings from the Toronto-McLean cohorts. Schizophr Bull. 42(3):772-81.

Pouget JG, Gonçalves VF, Nurmi EL, P Laughlin C, Mallya KS, McCracken JT, Aman MG, McDougle CJ, Scahill L, Misener VL, Tiwari AK, Zai CC, Brandl EJ, Felsky D, Leung AQ, Lieberman JA, Meltzer HY, Potkin SG, Niedling C, Steimer W, Leucht S, Knight J, Müller DJ and Kennedy JL (2015) Investigation of TSPO variants in schizophrenia and antipsychotic treatment outcomes. Pharmacogenomics. 16(1):5-22.

Changasi AH, Shams TA, Pouget JG and Müller DJ (2014) Genetics of antipsychotic drug outcome and implications for the clinician: into the limelight. Transl Dev Psychiatry. 2:24663.

Pouget JG, Shams TA, Tiwari AK and Müller DJ (2014) Pharmacogenetics and outcome with antipsychotic drugs. Dialogues Clin Neurosci. 16(4):555-66.

Rahman A., Zhou, Y. Q., Yee, Y., Dazai, J., Cahill, L. S., Kingdom, J., Macgowan, C. K., Sled, J. G. (2017). Ultrasound detection of altered placental vascular morphology based on hemodynamic pulse wave reflection. Am J Physiol Heart Circ Physiol. Articles in PresS.

Rennie, M. Y., Rahman, A., Whiteley, K. J., Sled, J. G., & Adamson, S. L. (2015). Site-specific increases in utero-and fetoplacental arterial vascular resistance in eNOS-deficient mice due to impaired arterial enlargement. Biology of reproduction, 92(2), 48.

Rotin LE, Gronda M, MacLean N, Hurren R, Wang X, Lin FH, Wrana J, Datti A, Barber DL, Minden MD, Slassi M, Schimmer AD. Ibrutinib synergizes with poly(ADP-ribose) glycohydrolase inhibitors to induce cell death in AML cells via a BTK-independent mechanism. Oncotarget. 2016 Jan 19;7(3):2765-79. doi: 10.18632/oncotarget.6409.

Rotin LE, Gronda M, Hurren R, Wang X, Minden MD, Slassi M, Schimmer AD. Investigating the synergistic mechanism between ibrutinib and daunorubicin in acute myeloid leukemia cells. Leuk Lymphoma. 2016 Feb 17:1-5. [Epub ahead of print]

Rotin LE, MacLean N, Aman A, Gronda M, Lin FH, Hurren R, Wang X, Wrana JL, Datti A, Al-Awar R, Minden MD, Schimmer AD. Erlotinib synergizes with the poly(ADP-ribose) glycohydrolase inhibitor ethacridine in acute myeloid leukemia cells. Haematologica. 2016 Nov;101(11):e449-e453.

Samuel N, Remke M, Rutka JT, Raught B and Malkin D, Proteomic analyses of CSF aimed at biomarker development for pediatric brain tumors.  J. Neuro-Oncology, DOI 10.1007/s11060-014-1432-3

Samuel N, Sayad A, Wilson G, Lemire M, Brown KR, Muthuswamy L, Hudson TJ, Moffat J.  entitled “Integrated genomic, transcriptomic and RNA-interference analysis of genes in somatic copy number gains in pancreatic ductal adenocarcinoma” Pancreas (in press).

Putman DM, Cooper TT, Sherman SE , Seneviratne AK, Hewitt M, Bell GI, Hess DA. Expansion of Umbilical Cord Blood Aldehyde Dehydrogenase expressing Cells Generates Myeloid Progenitor Cells that Stimulate Limb Revascularization. Accepted for Publication, March 2017, Stem Cells.

Seneviratne AK, Bell GI, Sherman S, Cooper T, Putman DM, Hess DA. “Expanded Hematopoietic progenitor cells reselected for high aldehyde dehydrogenase activity demonstrates islet regenerative functions. Stem Cells. 2016 Apr. 34(4): 873-887.  

Patel P, Brooks C, Seneviratne A, Hess DA and Séguin CA. Investigating microenvironmental regulation of human chordoma cell behaviour. PLOS ONE. 2014 Dec. 9(12):e115909.

Bell GI, Seneviratne AK, Nasri GN, Hess DA. Transplantation models to characterize the mechanism of stem cell induced islet regeneration. Current Protocols in Stem Cell Biology. 2013 Sep. 26:B:2B.4:2B.4.1–2B.4.35.

Sukhai MA, Prabha S, Hurren R, Rutledge AC, Lee AY, Sriskanthadevan S, Sun H, Wang X, Skrtic M,
Seneviratne A, Cusimano M, Jhas B, Gronda M, Maclean N, Cho EE, Spagnuolo PA, Sharmeen S, Gebbia M, Urbanus M, Eppert K, Dissanayake D, Jonet A, Dassonville-Klimpt A, Li X, Datti A, Ohashi PS, Wrana J, Rogers I, Sonnet P, Ellis WY, Corey SJ, Eaves C, Minden MD, Wang JC, Dick JE, Nislow C, Giaever G, Schimmer AD. The Journal of Clinical Investigation. Lyososomal disruption as a therapeutic strategy for acute myeloid leukemia. 2013 Jan. 123: 315-328.  

Sindhwani, S., Syed, A. M., Wilhelm, S., Glancy, D. R., Chen, Y. Y., Dobosz, M., & Chan, W. C. W. (2016). Three-Dimensional Optical Mapping of Nanoparticle Distribution in Intact Tissues. ACS Nano. 10(5): 5468–5478.

Steadman, P.E.*, Yin, C.*, Apramian, T., Zhou, E.T., Ishaque, A., Wang, X., Kuzyk, A., Warsi, N. (In press). Training the next generation of Canadian clinician-scientists: charting a path to success. Clinical Investigative Medicine. *Contributed equally to this work


Vetere, G., Kenney, J.W., Tran, L.M., Xia, F., Steadman, P.E., Parkinson, J., Josselyn, S.A., Frankland, P.W. (2017). Chemogenetic interrogation of a brainwide fear memory network in mice. Neuron. Apr 19;94(2):363-374.e4. doi:10.1016/j.neuron.2017.03.037.

Zhao, E., Zhou, E., Benesch, M., Dey, A., Liu, P., Steadman, P. E., Zaslavsky, K., Schneider, R., Kuzyk, A. (2016). Scientific Overview: CSCI-CITAC Annual General Meeting and Young Investigators‘ Forum 2015. Clinical Investigative Medicine. 2016 Oct 14;39(5):E142-E149


Steadman, P. E., Crudden J, Boutis K. (2015) Implementation of a Volunteer University Student Research Assistant Program in an Emergency Department: The Nuts and Bolts for Success. Canadian Journal of Emergency Medicine. doi:10.1017/cem.2015.79


Cahill, L. S., Steadman, P. E., Jones, C. E., Lalibert, C. L., Dazai, J., Lerch, J. P., Stefanovic, B., Sled, J. G. (2015) MRI-detectable changes in mouse brain structure induced by voluntary exercise. NeuroImage. doi:10.1016/j.neuroimage.2015.03.036


Abraham, L., Steadman, P. E. (2015) The State of Pharmaceutical Drug Coverage in Canada. University of Toronto Medical Journal. 92(1)                


Steadman, P. E., Crudden, J., Naranian, T., Oliveria, J. P., Boutis, K. (2015). The Professional Benefits for Volunteer Research Assistants in a Pediatric Emergency Department. J Emerg Med. doi:10.1016/j.jemermed.2014.06.038


Steadman, P. E., Crudden, J., Naranian, T., Oliveria, J. P., Boutis, K. (2015). The Effectiveness of Student-Volunteers For Research in a Pediatric Emergency Department. J Emerg Med. doi:10.1016/j.jemermed.2014.06.039


Steadman, P. E., Ellegood, J., Szulc, K. U., Turnbull, D. H., Joyner, A. L., Henkelman, R. M. and Lerch, J. P. (2014). Genetic effects on Cerebellar structure across mouse models of Autism using a magnetic resonance imaging atlas. Autism Res. doi:10.1002/aur.1344


Ellegood, J., Markx, S., Lerch, J. P., Steadman, P. E., Kushner, S. A., Henkelman, R. M., Karayiorgou, M., Gogos, J. A. (2014). Recapitulation of Human Neuroanatomical Phenotypes in a Mouse Model of the 22q11.2 Microdeletion. Molecular Psychiatry. doi: 10.1038/mp.2013.112.


Chakravarty, M. M., Steadman, P., van Eede, M. C., Calcott, R. D., Gu, V., Shaw, P., Raznahan, A., Louis, C. D., Lerch, J. P. (2013). Performing label-fusion-based segmentation using multiple automatically generated templates. Human brain mapping. doi:10.1002/hbm.22092.

Wang, X.*, Dubuc, A.M.*, Ramaswamy, V., Mack, S., Gendoo, D.M.A., Remke, M., Wu, X., Garzia, L., Luu, B., Cavalli, F., Peacock, J.,  López, B., Skowron, P., Zagzag D., Lyden, D., Hoffman, C., Cho, Y., Eberhart, C., MacDonald, T., Li, X., Van Meter, T., Northcott, P.A., Haibe-Kains, B., Hawkins, C., Rutka, J.T., Bouffet, E., Pfister, S.M., Korshunov, A., and Taylor, M.D. (2015) Medulloblastoma subgroups remain stable across primary and metastatic compartments. Acta Neuropathologica, Vol. 129(3): 449-457.

Morrissy, A.S., Garzia, L., Shih, D.J.H., Zuyderduyn, S., Huang, X., Skowron, P., Remke, M., Cavalli, F.M.G., Ramaswamy, V., Lindsay, P.E., Jelveh, S., Donovan, L.K., Wang, X., Luu, B., … Marra, M.A., and Taylor, M.D. (2016) Divergent clonal selection dominates medulloblastoma at recurrence. Nature. doi: 10.1038/nature16478

Ramaswamy, V., Remke, M., Adamski, J., Bartels, U., Tabori, U., Wang, X., Huang, A., Hawkins, C., Mabbott, C., Laperriere, N., Taylor, M.D., and Bouffet, E. (2014): Medulloblastoma subgroup-specific outcomes in irradiated children: who are the true high-risk patients? Neuro-Oncology(E-pub ahead of print).

Ng, E.*, Wang, X.*, Keow, J., and Yoon, J. (2015) Fostering mentorship for clinician-investigator trainees: overview and recommendations. Clinical and Investigative Medicine, 38(1): E1-10.

Faria, C.C., Golbourn, B., Dubuc, A.M., Remke, M., Diaz, R.J., Agnihotri, S., Luck, A., Sabha, N., Olsen, S., Wu, X., Garzia, L., Ramaswamy, V., Mack, S.C., Wang, X., Leadley, M., Reynaud, D., Ermini, L., Post, M., Northcott, P.A., Pfister, S.M., Croul, S., Kool, M., Korshunov, A., Smith, C.A., Taylor, M.D., and Rutka, J.T. (2015) Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma. Cancer Research, 75(1): 134-46.

Wang, X., Ramaswamy, V., and Taylor, M.D. (2014) What do the Sasquatch, Loch Ness Monster and “medulloblastoma” have in common? AANS Neurosurgeon, Volume 23, Number 1. *Featured article

Mack, S. C., Witt, H., Piro, R.M., Gu, L., Zuyderduyn, S., Stutz, A.M., Wang, X., Gallo, M., Garzia, L., Zayne, K., Zhang, X., Ramaswamy, V., Jager, N., Jones, D.T.W.,  Lichter, P., Dirks, P.B., Pfister, S.M., Korshunov, A., and Taylor, M.D. (2014) Epigenomic alterations define lethal CIMP positive ependymomas of infancy. Nature, 506(7489): 445-50.

Ramaswamy, V., Remke, M., Shih, D., Wang, X., Northcott, P.A., Faria, C.C., Raybaud, C., Tabori, U., Hawkins, C., Rutka, J., Taylor, M.D., and Bouffet, E. (2014) Duration of the pre-diagnostic interval in medulloblastoma is subgroup dependent. Pediatric Blood Cancer, 61(7): 1190-4.

Dubuc, A. M., Remke, M., Korshunov, A., Northcott, P. a, Zhan, S. H., Mendez-Lago, M., Kool, M., Jones, D. T. W., Unterberger, A., Morrissy, a S., Shih, D., Peacock, J., Ramaswamy, V., Rolider, A., Wang, X., Witt, H., Hielscher, T., … Taylor, M. D. (2012). Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma. Acta neuropathologica. doi:10.1007/s00401-012-1070-9

Northcott, P. a, Shih, D. J. H., Peacock, J., Garzia, L., Morrissy, a S., Zichner, T., Stütz, A. M., Korshunov, A., Reimand, J., Schumacher, S. E., Beroukhim, R., Ellison, D. W., Marshall, C. R., Lionel, A. C., Mack, S., Dubuc, A., Yao, Y., Ramaswamy, V., Luu, B., Rolider, A., Cavalli, F. m. g., Wang, X., Remke, M., Wu, X., … Taylor, M. D. (2012). Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature, 488(7409), 49–56. doi:10.1038/nature11327

Venugopal, C., Li, N., Wang, X., Manoranjan, B., Hawkins, C., Gunnarsson, T., Hollenberg, R., Klurfan, P., Murty, N., Kwiecien, J., Farrokhyar, F., Provias, J. P., Wynder, C., & Singh, S. K. (2012). Bmi1 marks intermediate precursors during differentiation of human brain tumor initiating cells. Stem Cell Research, 8(2), 141–153. doi:10.1016/j.scr.2011.09.00

Tsermoulas G, Turel MK, Wilcox JT, Shultz D, Farb R, Zadeh G, Bernstein M. (2017) Management of multiple meningiomas. J Neurosurgery: in press.

Wilcox, JT, Fehlings, MG, (2016) The acute clip contusion-compression model of cervical spinal cord injury in the rat. In: Neuromethods: Experimental Neurosurgery in Animal Models M. Janoswski, (Ed.). Springer vol. 116 © Springer Science+Business Media New York 2016. doi:10.1007/978-1-4939-3730-1_8


Wilcox JT, Vawda R, and Fehlings MG. (2015). Stem cell transplantation strategies after spinal cord injury. In: Stem Cells and Neurologic Disorders. Lescaudron, L. (ed). Science Publishers, Enbridge Ltd.: Enfield, NH, USA, pps. 61-95.

Harris S, Wilcox JT, and Fehlings MG (2013) Spinal Cord Injury: Clinical Trials and Translational Tribulations. In: Frontiers in Clinical Drug Research-Central Nervous System. Atta-Ur-Rahman, (Ed.). Bentham Science Publishers, Oak Park, IL, USA, 2013. eISBN 978-1-60805-779-5.


Wilcox JT, Harrop JS, Guest JD and Fehlings MG. (2011). Cell-based therapies for spinal cord injury: what does the neurosurgeon need to know? In: CNS Quarterly. Congress of Neurologic Surgeons Congress. 2011;3(1):22-24.

Wilcox JT*, Satkunendrarajah K*, Zuccato JA, Nassiri F, Fehlings MG. (2014) Neural stem cell transplantation enhances functional recovery and reduces astrogliosis in bilateral compressive-contusive cervical spinal cord injury. Original Research Article. Stem Cells Trans Med 2014;3(10):1148-59. *, co-primary authors.

Moonen G, Satkunendrarajah K, Wilcox JT, Badner A, Mothe A, Foltz W, Fehlings MG, Tator C. (2016) A new acute impact-compression lumbar spinal cord injury model in the rodent. J Neurotrauma 2016;33(3):278:89.

Iwasaki M, Wilcox JT, Nishimura Y, Zweckberger K, Suzuki H, Wang J, Liu Y, Karadimas S, Fehlings MG. (2014) Synergistic Effects of Self-assembling Peptide and Neural Stem/Progenitor Cells to Promote Tissue Repair and Forelimb Functional Recovery in Cervical Spinal Cord Injury. Biomaterials 2014;35(9):2617-29.

Yoon J, Appleton CT, Cecchini M, Correa R, Ram V, Wang XK, Ng E, Speechley M, Wilcox JT. (2013) It Begins With the Right Supervisor: Importance of Mentorship and Clinician-Investigator Trainee Satisfaction Levels in Canada. Clin Invest Med 2013;36(6):e269.

Antoun G, Ram VD, Wang X, Wilcox JT, Yoon J. (2013) Scientific overview: CSCI-CITAC Annual General Meeting and Young Investigator’s Forum 2012. Clin Invest Med 2013;36(5):E248-252.

Vawda R, Wilcox JT, Fehlings MG. (2012) Current stem cell treatment for spinal cord injury. Ind J Ortho 2012:46(1);10-18. DOI: 10.4103/0019-5413.91629.

Wilcox JT, Cadotte D, Fehlings MG (2012). Spinal cord clinical trials and the role for bioengineering. Neuroscience Letters 2012;519(2):93-102.

Wilcox JT, Lai JKY, Semple E, Brisson BA, Gartley C, Armstrong JN, Betts DH (2011). Neural Stem Sells and Synapticaly-competent Neurons Derived from Canine Embryonic Stem Cells by Lineage Selection with EGF and Noggin: Towards Large Animal Transplantation. PLoS One 2011;6(5):e19768.

Wilcox JT, Semple E, Gartley C, Brisson B, Perrault S, Tayade C, Becker S, Lanza R, Betts DH (2009). Characterization of canine embryonic stem cells derived from different niche microenvironments. Stem Cells Dev 2009;18(8):1167-1178.

Fehlings MG, Wilcox JT (2011). Spinal cord injury and pain. J Neurosurg Spine 2011;15(6):579-80.

Ruff CA*, Wilcox JT*, Fehlings MG. (2011) Cell-based transplantation strategies to promote plasticity following spinal cord injury. Exp Neurol 2011;235(1):78-90. *, co-primary authors.

Wu FT, Man S, Xu P, Chow A, Paez-Ribes M, Lee CR, Pirie-Shepherd SR,
Emmenegger U, Kerbel RS. (2016) Efficacy of Cotargeting Angiopoietin-2 and the VEGF Pathway in the Adjuvant Postsurgical Setting for Early Breast, Colorectal, and
Renal Cancers.
Cancer Res. 76(23):6988-7000. doi: 10.1158/0008-5472.CAN-16-0888.

Wu FT, Paez-Ribes M, Xu P, Man S, Bogdanovic E, Thurston G, Kerbel RS. (2016)
Aflibercept and Ang1 supplementation improve neoadjuvant or adjuvant chemotherapy in a preclinical model of resectable breast cancer.
Sci Rep. 6:36694. doi: 10.1038/srep36694.

Shaked Y, Pham E, Hariharan S, Magidey K, Beyar-Katz O, Xu P, Man S, Wu FT,
Miller V, Andrews D, Kerbel RS. (2016) Evidence Implicating Immunological Host Effects in the Efficacy of Metronomic Low-Dose Chemotherapy.
Cancer Res. 76(20):5983-5993. doi: 10.1158/0008-5472.CAN-16-0136

Wu FT, Lee CR, Bogdanovic E, Prodeus A, Gariépy J, Kerbel RS. (2015) Vasculotide reduces endothelial permeability and tumor cell extravasation in the absence of binding to or agonistic activation of Tie2. EMBO Mol Med. 7(6):770-87. doi: 10.15252/emmm.201404193.

Wu RY, Abdullah M, Määttänen P, Pilar AV, Scruten E, Johnson-Henry KC, Napper S, O’Brien C, Jones NL, Sherman P (2017). Protein kinase C δ signaling is required for dietary prebiotic-induced strengthening of intestinal epithelial barrier function. Scientific Reports. 18(7): 40820.


Li B, Lee C, Filler T, Hock A, Wu RY, Li Q, Chen S, Koike Y, Ip W, Chi L, Zani-Ruttenstock E, Määttänen P, Gonska T, Delgado Olguin P, Zani A, Sherman P, Pierro A (2017). Inhibition of corticotropin-releasing hormone receptor 1 and activation of receptor 2 protect against colonic injury and promote epithelium repair. Scientific Reports. Accepted for publication.


Wu RY, Jeffrey M, Johnson-Henry KC, Green-Johnson J, Sherman P (2017). Impact of prebiotics, probiotics and gut derived metabolites on host immunity. LymphoSign Journal. 4(1): 1-24.


Abrahamsson T, Wu RY, Sherman P (2017). Microbiota in functional gastrointestinal disorders in infancy: implications for management . Nestlé Nutrition Institute Workshop series. 88, 107-115.

Johnson-Henry KC, Abrahamsson T, Wu RY, Sherman P (2016). Probiotics, prebiotics, and synbiotics for the prevention of necrotizing enterocolitis. Advances in Nutrition.15:928-937.


C. West, Wu RY, Wong A, Stanisz AM, Yan R, Min KK, Pasyk M, McVey Neufeld K-A, Foster JA, Bienenstock J, Forsythe P, Kunze WA  (2016). Lactobacillus rhamnosus strain JB-1 reverses restrain stress-induced gut dysmotility. Neurogastroenterology and Motility. 1-11.


Wu RY, Sherman P (2015). Host-intestinal microbe interactions in human health and disease. University of Toronto Medical Journal. 92(3): 30-34.


Abrahamsson TR, Wu RY, Jenmalm MC (2015). Gut Microbiota and allergy: the importance of the pregnancy period. Pediatric Research. 77(1-2): 214-219.


Huizinga JD, Chen JH, Zhu YF, Pawelka A, McGinn RJ, Bardakjian BL, Parsons SP, Kunze WA, Wu RY, Bercik P, Khosh A, Chen S, Yin S, Zhang Q, Yu Y, Gao Q, Li K, Hu X, Zarate N, Collins P, Pistilli M, Ma J, Zhang R, Chen D (2014). The origin of segmentation motor activity in the intestine. Nature Communications. 5. 3326.


Wu RY, Pasyk M, Wang B, Forsythe P, Bienenstock J, Mao YK, Sharma P, Stanisz AM, Kunze WA (2013). Spatiotemporal maps reveal regional differences in the effects on gut motility for Lactobacillus reuteri and rhamnosus strains. Neurogastroenterology and Motility. 25(3): e205-214.

Ringuette, R., Atkins, M., Lagali, P. S., Bassett, E. A., Campbell, C., Mazerolle, C., Mears, A. J., Picketts, D. J., and Wallace, V. A. (2016) A Notch-Gli2 axis sustains Hedgehog responsiveness of late neural progenitors and Müller glia. Dev. Biol. 411, 85-100.

Ringuette, R., Wang, Y., Atkins, M., Mears, A. J., Yan, K., and Wallace, V. A. (2014) Combinatorial Hedgehog and mitogen signaling promotes the in vitro expansion but not retinal differentiation potential of retinal progenitor cells. Invest. Ophthalmol. Vis. Sci. 55, 43-54.

Voronova A, Yuzwa SA, Wang B, Zahr SK, Syal C, Wang J, Kaplan DR, Miller FD. (2017). Migrating interneurons secrete fractalkine to promote oligodendrocyte formation in the developing mammalian brain. Neuron. In Press.

Yang G, Cancino I, Zahr SK, Guskjolen A, Voronova A, Gallagher D, Frankland P, Miller F, Kaplan D. (2016). A Glo1-methylglyoxal pathway that is perturbed in maternal diabetes regulates embryonic and adult neural stem cell pools in offspring. Cell Reports. 17, 1022-1036.

Yuzwa S, Yang G, Borrett M, Clarke G, Cancino I, Zahr SK, Zandstra P, Kaplan D, Miller F. (2016). Proneurogenic ligands defined by modeling developing cortex growth factor communication networks. Neuron. 91, 988-1004.

Rodrigues DC, Kim DS, Yang G, Zaslavsky K, Ha K, Mok RSF, Ross PJ, Zhao M, Piekna A, Wei W, Blencowe BJ, Morris Q, Ellis J (2016). MECP2 is post-transcriptionally regulated during human neurodevelopment by combinatorial action of RNA-binding proteins and miRNAs. Cell Reports 17(3): 720-734

Khattak S, Brimble E, Zhang W, Zaslavsky K, Hendry J, Ross PJ, Mital S, Salter MW, Osborn LR, Ellis J (2015). Human induced pluripotent stem cell derived neurons as a model for Williams-Beuren syndrome. Mol Brain 8(1):77

Kim DS, Ross PJ, Zaslavsky K, Ellis J (2014). Optimizing neuronal differentiation from induced pluripotent stem cells to model ASD. Front Cell Neurosci 8:109.

Stone SS, Teixeira CM, Devito LM, Zaslavsky K, Josselyn SA, Lozano AM, Frankland PW (2011). Stimulation of entorhinal cortex promotes adult neurogenesis and facilitates spatial memory. J Neurosci 31(38): 13469-84.

Stone SSD, Teixeira CM, Zaslavsky K, Wheeler AL, Martinez-Canabal A, Wang AH, Sakaguchi M, Lozano AM and Frankland PW (2011). Functional convergence of developmentally- and adult-generated granule cells in dentate gyrus circuits supporting hippocampus-dependent memory. Hippocampus 21(12): 1348-62.  

Textbooks / Chapters

Dey, A., Nicholas, M., Vu, T., Carette, S., & Gakhal, N. (2017). Rheumatology. In Mukovozov &

Kim (Eds.), Toronto Notes 2017 (pp RH1-RH32). Toronto: Toronto Notes for Medical Students


Dey, A., Stadnick, H., Goldlist, B. (2016). Geriatric Medicine. In Merali & Woodfine (Eds.),

Toronto Notes 2016 (pp GM1-GM25). Toronto: Toronto Notes for Medical Students Inc.  

Dey, A., Samuel, N. Guolla, L., Hunyh, A., Hunyh, J., Hu, T, Bui, E., Murray, B., Tang-Wai, D. (2015). Neurology. In Hall & Premji (Eds.), Toronto Notes 2015 (pp N1-N55). Toronto: Toronto Notes for Medical Students Inc.    

Dey, A., Woodland, C., Lala, P., & Battistella, M. (2013). Commonly used drugs. In J. Hall, K. Piggott, M. Vojvodic & K. Zaslavsky (Eds.), Essentials of Clinical Examination Handbook (7 ed., pp. 585-599). Toronto: Thieme.

A. F. Khan, Bioengineering for Surgery: The Critical Engineer-Surgeon Interface - Chapter 8: Virtual Simulation - Abdomen. Elsevier, 2016.

Le Foll, B., Ng, E., Trigo, J. M., & Di Ciano, P. (2015). The Self-medication Hypothesis in Schizophrenia: What Have We Learned from Animal Models? In T. V Lipina & J. C. Roder (Eds.), Drug discovery for schizophrenia (pp. 70–88). Cambridge, UK: Royal Society of Chemistry. doi:10.1039/9781782622499-00070

Rennie, M. Y., Mu, J., Rahman, A., Qu, D., Whiteley, K. J., Sled, J. G., & Adamson, S. L. (2014). The Uteroplacental, Fetoplacental, and Yolk Sac Circulations in the Mouse. In Croy, B. A., Yamada, A. T., DeMayo, F. J., & Adamson, S. L. (Eds.). (2014), The guide to investigation of mouse pregnancy (pp. 201-210). Academic Press.

Vi L, Wu Y, Gan BS, and O’Gorman DB. Primary Dupuytren’s Disease cell interactions with the extra-cellular environment: a link to disease progression? Dupuytren’s Disease and Related Hyperproliferative Disorders – Principles, Research, and Clinical Perspectives, 2012: 151-159.

Wilcox JT, Fehlings MG (2011) The acute clip contusion-compression model of cervical spinal cord injury in the rat. In: Janowski M (ed) Neuromethods, Springer, Humana Press.

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