PM06: KNOWLEDGE BASE TREATMENT MONITOR-KBTM BASED ON GA-ANFIS ALGORITHM

Functions & goal

Model  KBTM (Figure1) uses inputs from: (a) gene expression (new clinical microarray data about over-expressions and under-expressions), and (b) therapy parameters.

Methods

With the application of genetic optimized Adaptive Neuro Fuzzy System (ANFIS), and ensemble methods - Figure 1, model generates an output signal called "success of one treatment phase (therapy)".  

Figure 1. KBTM  structure