Lesson 4.2 Teacher’s Guide

Below are the learning targets you are expected to master for this unit. Under each learning target is a number 1-4. As a pre-assessment, before the lesson begins, please circle the number that describes your current understanding of the learning target. Before the formative assessment, please draw a triangle around the number that describes your understanding of the learning target. Before the summative assessment, please draw a square around the number that describes your understanding of the learning target.

Learning Targets for Lesson 4.2

My self-assessment

1 - I have never seen this learning target before.

2 - I have seen this learning target, but I don't know what it means.

3 - I have seen this learning target, and I think I know what it means

4 - I can explain this learning target to another student.

I can describe the role of DNA and RNA is assembling protein molecules.

1 2 3 4

Lesson 4.2 Vocabulary

Below are the terms you are expected to master for this unit. Under each term is a number 1-4. As a pre- assessment, before the lesson begins, please circle the number that describes your current understanding of the terms. Before the summative assessment, please draw a square around the number that describes your understanding of the terms.

As you go through the lesson, write a definition (in your own words) in the middle column, and complete the Extra Practice column according to the key.

Term

1 - I have never seen this term before.

2 - I have seen this term, but I don't know what it means.

3- I have seen this term, and I think I know what it means

4- I can explain this term and its meaning to another student.

Definition

Extra practice (see key below)

Prefixes and Suffixes: Find out what the word parts mean, then put them together.

Sentence: Use the term properly in a complete sentence.

Sketch: Draw a sketch of the term

Examples: Give examples of the term.

On your own: Choose another option or write an alternative definition using your prior knowledge.

1. Ribonucleic acid (RNA)

1 2 3 4

On your own:

2. Transcription

1 2 3 4

Prefixes and Suffixes:

3. Translation

1 2 3 4

Prefixes and Suffixes:

4. Messenger RNA (mRNA)

1 2 3 4

5. . RNA (rRNA)

1 2 3 4

6. Transfer RNA (tRNA)

1 2 3 4

label amino acid, tRNA, anticodon

7. Protein

1 2 3 4

EXAMPLES:

8. Protein synthesis

1 2 3 4

FILL IN THE BLANK:

The work of the cell is carried out primarily by ______________.

Protein function depends on the _____________ sequence and the shape it takes as a consequence of the interactions between those amino acids.

Lesson 4.2 Activities:

Click on the link below for all Lesson 4.2 activities

Lesson 4.2 Activities

Additional online Activities:

What is a protein? (requires Flash; will not run natively on iOS devices)

Transcribe and Translate a Gene (requires Flash; will not run natively on iOS devices)

A Science Odyssey: You Try It: DNA Workshop (requires Shockwave; will not run natively on iOS devices)

Links to Relatively Recent Research for Lesson 4.2

Ribosome regulates viral protein synthesis, revealing ...

Discovering the Relationship Between DNA and Protein ...

Protein synthesis is a novel determinant of aging in …

Protein synthesis studied in stem cells for the first time

Links to information on a scientist for Lesson 4.2

ORNL's Unsung Discovery

The Discovery of Messenger RNA

Lesson 4.2 Formative Assessment

Multiple Choice Questions:

____ 1. Unlike DNA, RNA contains

a.	adenine.
b.	uracil.
c.	phosphate groups.
d.	thymine.

____ 2. Which type of RNA brings the information in the genetic code from the nucleus to other parts of the cell?

a.	rRNA
b.	tRNA
c.	mRNA
d.	RNA polymerase

____ 3. What happens during translation?

a.	Messenger RNA is made from a DNA code.
b.	The cell uses a messenger RNA code to make proteins.
c.	Transfer RNA is made from a messenger RNA code.
d.	Copies of DNA molecules are made.

____ 4. Genes contain instructions for assembling

a.	DNA
b.	RNA
c.	proteins.
d.	mutagens.

____ 5. Which is the correct sequence of the transfer of information in most organisms?

a.	protein to DNA to RNA
b.	RNA to DNA to protein
c.	DNA to RNA to protein
d.	RNA to protein to DNA

____ 6. In cells with a nucleus,

a.	Transcription takes place in the cytoplasm, and translation takes place in the nucleus.
b.	Transcription takes place in the nucleus, and translation takes place at the ribosome in the cytoplasm.
c.	Transcription and translation both take place in the nucleus.
d.	Transcription and translation both take place at the ribosomes in the cytoplasm.

Short Answer questions

7. A gene has the following base sequence;

GAC AAG TCC ACA ATC

Write the sequence of the mRNA molecule transcribed from this gene.

_____________________________________________________

Use the chart below to write the amino acid sequence of the protein.

_____________________________________________________

Codons_aminoacids_table by Onie / CC BY-SA 3.0

Lesson 4.2 Formative Assessment Key

1. B

2. C

3. B

4. C

5. C

6. B

Short Answer:

7. CUG UUC AGG UGU UAG

Leu-Phe-Arg-Cys-stop