2015 Cancer Biology Student     Organization Publications

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The N-terminus of the Rb Protein Inhibits DNA Replication Via a Bipartite Mechanism Disrupted In Partially Penetrant Retinoblastomas.

Borysov SI, Nepon-Sixt BS, Alexandrow MG.

Mol Cell Biol. 2015 Dec 28. pii: MCB.00636-15. [Epub ahead of print]

Chemoproteomics Reveals Novel Protein and Lipid Kinase Targets of Clinical CDK4/6 Inhibitors in Lung Cancer.

Sumi NJ, Kuenzi BM, Knezevic CE, Remsing Rix LL, Rix U.

ACS Chem Biol. 2015 Dec 18;10(12):2680-6. doi: 10.1021/acschembio.5b00368. Epub 2015 Oct 5.

Clostridium perfringens enterotoxin C-terminal domain labeled to fluorescent dyes for in vivo visualization of micrometastatic chemotherapy-resistant ovarian cancer.

Cocco E, Shapiro EM, Gasparrini S, Lopez S, Schwab CL, Bellone S, Bortolomai I, Sumi NJ, Bonazzoli E, Nicoletti R, Deng Y, Saltzman WM, Zeiss CJ, Centritto F, Black JD, Silasi DA, Ratner E, Azodi M, Rutherford TJ, Schwartz PE, Pecorelli S, Santin AD.

Int J Cancer. 2015 Dec 1;137(11):2618-29. doi: 10.1002/ijc.29632. Epub 2015 Aug 18.

Identification of Synergistic, Clinically Achievable, Combination Therapies for Osteosarcoma.

Yu D, Kahen E, Cubitt CL, McGuire J, Kreahling J, Lee J, Altiok S, Lynch CC, Sullivan DM, Reed DR.

Sci Rep. 2015 Nov 25;5:16991. doi: 10.1038/srep16991.

Neutralization of tumor acidity improves antitumor responses to immunotherapeutic interventions.

Pilon-Thomas S, Kodumudi KN, El-Kenawi AE, Russell S, Weber AM, Luddy K, Damaghi M, Wojtkowiak JW, Mulé JJ, Ibrahim-Hashim A, Gillies RJ.

Cancer Res. 2015 Dec 30. pii: canres.1743.2015. [Epub ahead of print]

Suppression of Reserve MCM Complexes Chemosensitizes to Gemcitabine and 5-Fluorouracil.

Bryant VL, Elias RM, McCarthy SM, Yeatman TJ, Alexandrow MG.

Mol Cancer Res. 2015 Sep;13(9):1296-305. doi: 10.1158/1541-7786.MCR-14-0464. Epub 2015 Jun 10.

Analysis of DNA replication associated chromatin decondensation: in vivo assay for understanding chromatin remodeling mechanisms of selected proteins.

Borysov S, Bryant VL, Alexandrow MG.

Methods Mol Biol. 2015;1288:289-303. doi: 10.1007/978-1-4939-2474-5_16.

TP53 and MDM2 single nucleotide polymorphisms influence survival in non-del(5q) myelodysplastic syndromes.

McGraw KL, Cluzeau T, Sallman DA, Basiorka AA, Irvine BA, Zhang L, Epling-Burnette PK, Rollison DE, Mallo M, Sokol L, Solé F, Maciejewski J, List AF.

Oncotarget. 2015 Oct 27;6(33):34437-45. doi: 10.18632/oncotarget.5255.

The relationship of TP53 R72P polymorphism to disease outcome and TP53 mutation in myelodysplastic syndromes.

McGraw KL, Zhang LM, Rollison DE, Basiorka AA, Fulp W, Rawal B, Jerez A, Billingsley DL, Lin HY, Kurtin SE, Yoder S, Zhang Y, Guinta K, Mallo M, Solé F, Calasanz MJ, Cervera J, Such E, González T, Nevill TJ, Haferlach T, Smith AE, Kulasekararaj A, Mufti G, Karsan A, Maciejewski JP, Sokol L, Epling-Burnette PK, Wei S, List AF.

Blood Cancer J. 2015 Mar 13;5:e291. doi: 10.1038/bcj.2015.11.

Evaluating kinase ATP uptake and tyrosine phosphorylation using multiplexed quantification of chemically labeled and post-translationally modified peptides.

Fang B, Hoffman MA, Mirza AS, Mishall KM, Li J, Peterman SM, Smalley KS, Shain KH, Weinberger PM, Wu J, Rix U, Haura EB, Koomen JM.

Methods. 2015 Jun 15;81:41-9. doi: 10.1016/j.ymeth.2015.03.006. Epub 2015 Mar 14.

The Role of nAChR and Calcium Signaling in Pancreatic Cancer Initiation and Progression.

Schaal C, Padmanabhan J, Chellappan S.

Cancers (Basel). 2015 Jul 31;7(3):1447-71. doi: 10.3390/cancers7030845. Review.

YAP1 Regulates OCT4 Activity and SOX2 Expression to Facilitate Self-Renewal and Vascular Mimicry of Stem-Like Cells.

Bora-Singhal N, Nguyen J, Schaal C, Perumal D, Singh S, Coppola D, Chellappan S.

Stem Cells. 2015 Jun;33(6):1705-18. doi: 10.1002/stem.1993.

Current and emerging therapies for bone metastatic castration-resistant prostate cancer.

Frieling JS, Basanta D, Lynch CC.

Cancer Control. 2015 Jan;22(1):109-20. Review.

Disseminating Melanoma Cells Surf on Calcium Waves.

Sun J, Lin S, Keeley T, Yang S.

Mol Cell Oncol. 2015;2(4). pii: e1002714.

Long non-coding RNAs (LncRNA) regulated by transforming growth factor (TGF) β: LncRNA-hit-mediated TGFβ-induced epithelial to mesenchymal transition in mammary epithelia.

Richards EJ, Zhang G, Li ZP, Permuth-Wey J, Challa S, Li Y, Kong W, Dan S, Bui MM, Coppola D, Mao WM, Sellers TA, Cheng JQ.

J Biol Chem. 2015 Mar 13;290(11):6857-67. doi: 10.1074/jbc.M114.610915. Epub 2015 Jan 20.

The gene pair PRR11 and SKA2 shares a NF-Y-regulated bidirectional promoter and contributes to lung cancer development.

Wang Y, Zhang Y, Zhang C, Weng H, Li Y, Cai W, Xie M, Long Y, Ai Q, Liu Z, Du G, Wang S, Niu Y, Song F, Ozaki T, Bu Y.

Biochim Biophys Acta. 2015 Sep;1849(9):1133-44. doi: 10.1016/j.bbagrm.2015.07.002. Epub 2015 Jul 8.

HDAC Inhibition Upregulates PD-1 Ligands in Melanoma and Augments Immunotherapy with PD-1Blockade.

Woods DM, Sodré AL, Villagra A, Sarnaik A, Sotomayor EM, Weber J.

Cancer Immunol Res. 2015 Dec;3(12):1375-85. doi: 10.1158/2326-6066.CIR-15-0077-T. Epub 2015 Aug 21.

A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer.

Richards EJ, Permuth-Wey J, Li Y, Chen YA, Coppola D, Reid BM, Lin HY, Teer JK, Berchuck A, Birrer MJ, Lawrenson K, Monteiro AN, Schildkraut JM, Goode EL, Gayther SA, Sellers TA, Cheng JQ.

Oncotarget. 2015 Oct 27;6(33):34745-57. doi: 10.18632/oncotarget.5784.

Differential association of STK11 and TP53 with KRAS mutation-associated gene expression, proliferation and immune surveillance in lung adenocarcinoma.

Schabath MB, Welsh EA, Fulp WJ, Chen L, Teer JK, Thompson ZJ, Engel BE, Xie M, Berglund AE, Creelan BC, Antonia SJ, Gray JE, Eschrich SA, Chen DT, Cress WD, Haura EB, Beg AA.

Oncogene. 2015 Oct 19. doi: 10.1038/onc.2015.375. [Epub ahead of print]

The Retinoblastoma Tumor Suppressor Transcriptionally Represses Pak1 in Osteoblasts.

Sosa-García B, Vázquez-Rivera V, González-Flores JN, Engel BE, Cress WD, Santiago-Cardona PG.

PLoS One. 2015 Nov 10;10(11):e0142406. doi: 10.1371/journal.pone.0142406. eCollection 2015.

GOLPH3L is a Novel Prognostic Biomarker for Epithelial Ovarian Cancer.

Feng Y, He F, Wu H, Huang H, Zhang L, Han X, Liu J.

J Cancer. 2015 Jul 27;6(9):893-900. doi: 10.7150/jca.11865. eCollection 2015.