Jurriaan Plesman, BA (Psych), Post Grad Dip Clin Nutr


In considering the multiplicity of factors in dealing with mood disorders, scientists now agree that nutrition plays a foremost role in the mood disorders. Hence, the emphasis on vitamins and minerals etc etc. They often overlook, however, that in order to convert the nutrients in our food to feel good neurotransmitters and hormones you need biological energy called adenosine-triphosphate (ATP). Without ATP we cannot produce the necessary feel-good chemicals needed[1]. Now it just happens to be the case that about 90% of people with some some sort personality disorder suffer from either hypoglycemia[2] or pre-diabetes which is a disease marked by a faulty insulin hormone, that interferes with the production of ATP.

This illness can be treated without resorts to drugs by the adoption of the hypoglycemic diet.

Hence from a practical point of view, this is the first factor to consider if you are dealing with a mood disorder. In fact, hypoglycemia is the forerunner of diabetes and diabetes which in turn is the forerunner of all sorts of immune disorders, each with its own set of psychological effects.

It is not enough to say that treatment of mood disorders is a COMPLEX matter. You need to PRIORITISE your multiple factors from the most common to the less frequent.

In my practice,  I know from experience that 1) the most common factor is insulin resistance,  hypoglycemia and diabetes. This is followed by 2) heavy metal intoxication and such things as allergies, Celiac disease, hypothyroidism, Crohn's Disease,  Colitis and various other digestive disorders.  Here you really find a plethora of factors that makes mood disorders indeed a complex matter. (See: Silent Diseases and Mood Disorders and Notes on Hypoglycia and Pyroluria.). All of these factors may interferes with your gut's ability to convert nutrients in the necessary neurotransmitters and hormones. You also need to take into account the unique biochemical individuality[3] of the person, where we find no two people with let us say PTSD, anxiety or schizophrenia are the same.

Most people can help themselves with category 1) and 2) above, provided they are prepared to read and study the topics at hand.

Beyond this, you need the assistance of professional experts in the field of clinical nutrition, or nutritional biochemistry or medicine, who are able to test for nutritional abnormal factors responsible for the problem at hand.

Try to develop a "method" to overcome the complexity of mood disorders from the simple to the more complex.  Then last of all, you need to consider the psychological factors.  Again this can be done by the person himself by studying Self-Help Psychotherapy Course.

This course is also available at: Nine weeks Psychotherapy Course or

In Getting off the Hook (freely available at the internet) starting at Page 36


[1] “An active cell requires more than 2 million ATP molecules per second. The store of ATP in a human body is sufficient to satisfy a person’s needs for only a few seconds, therefore, the store needs to be continuously replenished.” here.and Here

[2] Stephen Gyland study

[3] See Roger Williams at Wikipedia