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| A | B | C | D | E | F | |
|---|---|---|---|---|---|---|
1 | Parameter | Source | Comments | Value | ||
2 | YLL burden of cancer | Charts at http://www.plosone.org/article/info:doi/10.1371/journal.pone.0034569 | Excludes overseas burden, non-mortality burden | 10000000 | ||
3 | Expected reduction of burden attributable to research | See note | 0.5 | |||
4 | Yearly YLL saved | Calculation | 5000000 | |||
5 | Yearly research spend | http://report.nih.gov/categorical_spending.aspx | Excludes private and overseas funding | 5000000000 | ||
6 | Time delay to get benefits | Assumption | 50 | |||
7 | Discount rate | Assumption | 0.03 | |||
8 | Pop growth | http://blogs.census.gov/2012/12/12/what-a-difference-four-years-make-u-s-population-projected-to-grow-at-a-slower-pace-over-the-next-five-decades/ | 0.00655031784 | |||
9 | Net benefit discount rate | Calculation | 0.9772333183 | |||
10 | Total spend | Calculation | 132508284636 | |||
11 | Discount applied to total benefits | Calculation | 0.3161646283 | |||
12 | Total benefits | Calculation | 47482667.63 | |||
13 | Cost per YLL | Calculation | 2790.66639 | |||
14 | Ratio to DALYs saved by bednets | Calculation | Based on $76.21/DALY from spreadsheet at http://www.givewell.org/international/technical/programs/insecticide-treated-nets#HowcosteffectiveisLLINdistribution | 36.61811297 | ||
15 | Equiv cost per SSA child saved | Calculation | Based on ~30 DALYs per SSA child saved | 83719.99169 | ||
16 | Value of YLL at $5mm per life | Calculation | 62500 | |||
17 | ROI at $5mm per life | Calculation | 22.3960844 | |||
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