Drug Screening Program results - Chordoma Foundation
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TargetDrugModelStudy #% TGIP-value
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CDK4/6Palbociclib
SF8894 (1)
CF4590.0001
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CDK4/6Palbociclib
SF8894 (2)
CF8340.5669
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CDK4/6Palbociclib
SF8894 (3)
CF19490.0019
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CDK4/6PalbociclibU-CH1CF11000.0106
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CDK4/6PalbociclibCF365CF15870.0001
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CDK4/6PalbociclibCF322CF16710.0071
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CDK4/6PalbociclibCH22CF17610.0029
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CDK4/6PalbociclibCF359CF18540.0662
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CDK4/6RibociclibSF8894CF8240.813
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EGFRAfatinib*U-CH1CF11000.0067
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EGFRAfatinib*U-CH1CF3870.0051
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EGFRAfatinib*SF8894CF4780.0001
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EGFRAfatinibU-CH1CF3930.003
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EGFRAfatinibSF8894CF4870.0001
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EGFRAfatinibSF8894CF8850.0156
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EGFRAfatinibSF8894CF13680.0037
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EGFRAfatinibU-CH1CF141000.0007
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EGFRAfatinibCF365CF151000.0001
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EGFRAfatinibCF322CF16920.0007
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EGFRAfatinibCH22CF17560.0066
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EGFRAfatinibCF359BCF18330.3843
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EGFRCetuximabSF8894CF4600.0001
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EGFRCetuximabU-CH1CF11000.0044
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EGFRLapatinibSF8894CF8250.8029
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EGFROsimertinibCF365CF15410.0049
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EGFR + CDK4/6
Cetuximab + Palbociclib
SF8894CF4780.0001
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FGFRARQ087SF8894CF700.8824
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FGFRARQ087U-CH1CF500.9938
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HDACPanobinostatSF8894CF130
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HDACPanobinostatU-CH1CF141
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HDACVorinostatSF8894CF13460.0705
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HDACVorinostatU-CH1CF14280.4157
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PDGFRImatinibCF365CF15230.2457
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PDGFRImatinibCF322CF1600.5505
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PDGFRImatinibCH22CF1700.8271
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PDGFRImatinibCF359CF18230.682
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ProteasomeBortezomibSF8894CF770.9908
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ProteasomeBortezomibU-CH1CF6140.8528
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Proteasome + Topoisomerase
Bortezomib +Topotecan
SF8894CF7660.0018
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Proteasome + Topoisomerase
Bortezomib +Topotecan
U-CH1CF6550.1505
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STAT3NapabucasinSF8894CF13450.061
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STAT3NapabucasinUCH1CF1400.6327
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